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NNNN vs QDEL vs HOLX vs BIO vs TMO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NNNN
Anbio Biotechnology Class A Ordinary Shares

Medical - Instruments & Supplies

HealthcareNASDAQ • DE
Market Cap$1.13B
5Y Perf.+286.2%
QDEL
QuidelOrtho Corporation

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$737M
5Y Perf.-72.9%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+19.2%
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.87B
5Y Perf.-4.1%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$172.80B
5Y Perf.-12.1%

NNNN vs QDEL vs HOLX vs BIO vs TMO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NNNN logoNNNN
QDEL logoQDEL
HOLX logoHOLX
BIO logoBIO
TMO logoTMO
IndustryMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - DevicesMedical - Diagnostics & Research
Market Cap$1.13B$737M$16.97B$6.87B$172.80B
Revenue (TTM)$16M$2.66B$4.13B$2.59B$45.20B
Net Income (TTM)$5M$-1.21B$544M$169M$6.86B
Gross Margin62.1%56.6%52.8%51.9%39.4%
Operating Margin26.5%-37.0%17.5%9.2%17.8%
Forward P/E461.4x6.0x17.2x27.4x18.7x
Total Debt$0.00$2.80B$2.63B$1.53B$40.85B
Cash & Equiv.$12M$170M$1.96B$532M$9.86B

NNNN vs QDEL vs HOLX vs BIO vs TMOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NNNN
QDEL
HOLX
BIO
TMO
StockFeb 25May 26Return
Anbio Biotechnology… (NNNN)100386.2+286.2%
QuidelOrtho Corpora… (QDEL)10027.1-72.9%
Hologic, Inc. (HOLX)100119.2+19.2%
Bio-Rad Laboratorie… (BIO)10095.9-4.1%
Thermo Fisher Scien… (TMO)10087.9-12.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: NNNN vs QDEL vs HOLX vs BIO vs TMO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NNNN leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. QuidelOrtho Corporation is the stronger pick specifically for valuation and capital efficiency. HOLX and TMO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
NNNN
Anbio Biotechnology Class A Ordinary Shares
The Growth Play

NNNN carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 21.9%, EPS growth 366.7%, 3Y rev CAGR 22.7%
  • 347.8% 10Y total return vs TMO's 222.6%
  • Beta 0.46, current ratio 10.71x
  • 21.9% revenue growth vs QDEL's -1.9%
Best for: growth exposure and long-term compounding
QDEL
QuidelOrtho Corporation
The Value Play

QDEL is the #2 pick in this set and the best alternative if value is your priority.

  • Lower P/E (6.0x vs 18.7x)
Best for: value
HOLX
Hologic, Inc.
The Defensive Pick

HOLX ranks third and is worth considering specifically for sleep-well-at-night.

  • Lower volatility, beta 0.45, Low D/E 52.0%, current ratio 3.75x
  • Beta 0.45 vs QDEL's 2.28, lower leverage
Best for: sleep-well-at-night
BIO
Bio-Rad Laboratories, Inc.
The Healthcare Pick

Among these 5 stocks, BIO doesn't own a clear edge in any measured category.

Best for: healthcare exposure
TMO
Thermo Fisher Scientific Inc.
The Income Pick

TMO is the clearest fit if your priority is income & stability.

  • Dividend streak 8 yrs, beta 1.07, yield 0.4%
  • 0.4% yield; 8-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthNNNN logoNNNN21.9% revenue growth vs QDEL's -1.9%
ValueQDEL logoQDELLower P/E (6.0x vs 18.7x)
Quality / MarginsNNNN logoNNNN31.0% margin vs QDEL's -45.6%
Stability / SafetyHOLX logoHOLXBeta 0.45 vs QDEL's 2.28, lower leverage
DividendsTMO logoTMO0.4% yield; 8-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)NNNN logoNNNN+289.7% vs QDEL's -70.3%
Efficiency (ROA)NNNN logoNNNN26.4% ROA vs QDEL's -20.7%, ROIC 28.3% vs -13.6%

NNNN vs QDEL vs HOLX vs BIO vs TMO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NNNNAnbio Biotechnology Class A Ordinary Shares

Segment breakdown not available.

QDELQuidelOrtho Corporation
FY 2023
Other
100.0%$483M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B

NNNN vs QDEL vs HOLX vs BIO vs TMO — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNNNNLAGGINGBIO

Income & Cash Flow (Last 12 Months)

NNNN leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 2805.9x NNNN's $16M. NNNN is the more profitable business, keeping 31.0% of every revenue dollar as net income compared to QDEL's -45.6%. On growth, TMO holds the edge at +6.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
RevenueTrailing 12 months$16M$2.7B$4.1B$2.6B$45.2B
EBITDAEarnings before interest/tax$5M-$649M$974M-$315M$10.5B
Net IncomeAfter-tax profit$5M-$1.2B$544M$169M$6.9B
Free Cash FlowCash after capex$3M-$75M$1000M$357M$6.7B
Gross MarginGross profit ÷ Revenue+62.1%+56.6%+52.8%+51.9%+39.4%
Operating MarginEBIT ÷ Revenue+26.5%-37.0%+17.5%+9.2%+17.8%
Net MarginNet income ÷ Revenue+31.0%-45.6%+13.2%+6.5%+15.2%
FCF MarginFCF ÷ Revenue+20.0%-2.8%+24.2%+13.8%+14.9%
Rev. Growth (YoY)Latest quarter vs prior year-36.0%-10.5%+2.5%+1.1%+6.2%
EPS Growth (YoY)Latest quarter vs prior year-2.7%-6.1%-9.2%-9.5%+11.3%
NNNN leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

QDEL leads this category, winning 4 of 6 comparable metrics.

At 9.1x trailing earnings, BIO trades at a 98% valuation discount to NNNN's 461.4x P/E. On an enterprise value basis, BIO's 16.5x EV/EBITDA is more attractive than NNNN's 437.3x.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
Market CapShares × price$1.1B$737M$17.0B$6.9B$172.8B
Enterprise ValueMkt cap + debt − cash$1.1B$3.4B$17.6B$7.9B$203.8B
Trailing P/EPrice ÷ TTM EPS461.43x-0.65x30.53x9.13x26.21x
Forward P/EPrice ÷ next-FY EPS est.5.96x17.21x27.40x18.71x
PEG RatioP/E ÷ EPS growth rate12.41x
EV / EBITDAEnterprise value multiple437.29x17.39x16.53x18.72x
Price / SalesMarket cap ÷ Revenue138.56x0.27x4.14x2.66x3.88x
Price / BookPrice ÷ Book value/share63.57x0.38x3.43x0.93x3.27x
Price / FCFMarket cap ÷ FCF545.16x18.44x18.33x27.46x
QDEL leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

NNNN leads this category, winning 6 of 9 comparable metrics.

NNNN delivers a 29.1% return on equity — every $100 of shareholder capital generates $29 in annual profit, vs $-56 for QDEL. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to QDEL's 1.46x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs BIO's 5/9, reflecting strong financial health.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
ROE (TTM)Return on equity+29.1%-56.3%+11.0%+2.4%+13.2%
ROA (TTM)Return on assets+26.4%-20.7%+6.1%+2.2%+6.4%
ROICReturn on invested capital+28.3%-13.6%+9.4%+2.6%+7.5%
ROCEReturn on capital employed+12.5%-18.0%+8.8%+2.9%+9.1%
Piotroski ScoreFundamental quality 0–956756
Debt / EquityFinancial leverage1.46x0.52x0.21x0.76x
Net DebtTotal debt minus cash-$12M$2.6B$667M$999M$31.0B
Cash & Equiv.Liquid assets$12M$170M$2.0B$532M$9.9B
Total DebtShort + long-term debt$0$2.8B$2.6B$1.5B$40.9B
Interest CoverageEBIT ÷ Interest expense-5.18x8.00x-2.49x5.89x
NNNN leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NNNN leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in NNNN five years ago would be worth $44,783 today (with dividends reinvested), compared to $930 for QDEL. Over the past 12 months, NNNN leads with a +289.7% total return vs QDEL's -70.3%. The 3-year compound annual growth rate (CAGR) favors NNNN at 64.8% vs QDEL's -50.3% — a key indicator of consistent wealth creation.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
YTD ReturnYear-to-date-12.3%-62.4%+1.9%-16.7%-21.4%
1-Year ReturnPast 12 months+289.7%-70.3%+35.3%+5.5%+13.6%
3-Year ReturnCumulative with dividends+347.8%-87.7%-8.5%-32.8%-13.4%
5-Year ReturnCumulative with dividends+347.8%-90.7%+16.8%-57.9%+1.9%
10-Year ReturnCumulative with dividends+347.8%-34.6%+124.3%+79.3%+222.6%
CAGR (3Y)Annualised 3-year return+64.8%-50.3%-2.9%-12.4%-4.7%
NNNN leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.45 beta — it tends to amplify market swings less than QDEL's 2.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs QDEL's 27.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
Beta (5Y)Sensitivity to S&P 5000.46x2.28x0.45x0.91x1.07x
52-Week HighHighest price in past year$55.65$38.99$76.04$343.12$643.99
52-Week LowLowest price in past year$6.34$10.22$53.62$211.43$385.46
% of 52W HighCurrent price vs 52-week peak+46.4%+27.8%+100.0%+74.1%+72.2%
RSI (14)Momentum oscillator 0–10044.134.569.136.143.9
Avg Volume (50D)Average daily shares traded34K2.2M10.3M304K1.9M
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

TMO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: QDEL as "Hold", HOLX as "Hold", BIO as "Buy", TMO as "Buy". Consensus price targets imply 40.8% upside for TMO (target: $655) vs 3.9% for HOLX (target: $79). TMO is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.

MetricNNNN logoNNNNAnbio Biotechnolo…QDEL logoQDELQuidelOrtho Corpo…HOLX logoHOLXHologic, Inc.BIO logoBIOBio-Rad Laborator…TMO logoTMOThermo Fisher Sci…
Analyst RatingConsensus buy/hold/sellHoldHoldBuyBuy
Price TargetConsensus 12-month target$12.25$79.00$312.50$654.67
# AnalystsCovering analysts15421442
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises08
Dividend / ShareAnnual DPS$1.69
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+4.4%+4.3%+1.7%
TMO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

NNNN leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). QDEL leads in 1 (Valuation Metrics).

Best OverallAnbio Biotechnology Class A… (NNNN)Leads 3 of 6 categories
Loading custom metrics...

NNNN vs QDEL vs HOLX vs BIO vs TMO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NNNN or QDEL or HOLX or BIO or TMO a better buy right now?

For growth investors, Anbio Biotechnology Class A Ordinary Shares (NNNN) is the stronger pick with 21.

9% revenue growth year-over-year, versus -1. 9% for QuidelOrtho Corporation (QDEL). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 1x trailing P/E (27. 4x forward), making it the more compelling value choice. Analysts rate Bio-Rad Laboratories, Inc. (BIO) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NNNN or QDEL or HOLX or BIO or TMO?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 1x versus Anbio Biotechnology Class A Ordinary Shares at 461. 4x. On forward P/E, QuidelOrtho Corporation is actually cheaper at 6. 0x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — NNNN or QDEL or HOLX or BIO or TMO?

Over the past 5 years, Anbio Biotechnology Class A Ordinary Shares (NNNN) delivered a total return of +347.

8%, compared to -90. 7% for QuidelOrtho Corporation (QDEL). Over 10 years, the gap is even starker: NNNN returned +347. 8% versus QDEL's -34. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NNNN or QDEL or HOLX or BIO or TMO?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 45β versus QuidelOrtho Corporation's 2. 28β — meaning QDEL is approximately 403% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 146% for QuidelOrtho Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — NNNN or QDEL or HOLX or BIO or TMO?

By revenue growth (latest reported year), Anbio Biotechnology Class A Ordinary Shares (NNNN) is pulling ahead at 21.

9% versus -1. 9% for QuidelOrtho Corporation (QDEL). On earnings-per-share growth, the picture is similar: Anbio Biotechnology Class A Ordinary Shares grew EPS 366. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, NNNN leads at 22. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NNNN or QDEL or HOLX or BIO or TMO?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus -41. 5% for QuidelOrtho Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NNNN leads at 24. 4% versus -33. 7% for QDEL. At the gross margin level — before operating expenses — NNNN leads at 71. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NNNN or QDEL or HOLX or BIO or TMO more undervalued right now?

On forward earnings alone, QuidelOrtho Corporation (QDEL) trades at 6.

0x forward P/E versus 27. 4x for Bio-Rad Laboratories, Inc. — 21. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for TMO: 40. 8% to $654. 67.

08

Which pays a better dividend — NNNN or QDEL or HOLX or BIO or TMO?

In this comparison, TMO (0.

4% yield) pays a dividend. NNNN, QDEL, HOLX, BIO do not pay a meaningful dividend and should not be held primarily for income.

09

Is NNNN or QDEL or HOLX or BIO or TMO better for a retirement portfolio?

For long-horizon retirement investors, Anbio Biotechnology Class A Ordinary Shares (NNNN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

46), +347. 8% 10Y return). QuidelOrtho Corporation (QDEL) carries a higher beta of 2. 28 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NNNN: +347. 8%, QDEL: -34. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NNNN and QDEL and HOLX and BIO and TMO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: NNNN is a small-cap high-growth stock; QDEL is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock; TMO is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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NNNN

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 18%
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QDEL

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 33%
Run This Screen
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HOLX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 7%
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BIO

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
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TMO

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 9%
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Revenue Growth>
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(NNNN: -36.0% · QDEL: -10.5%)

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