Medical - Instruments & Supplies
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5 / 10Stock Comparison
NNNN vs QDEL vs HOLX vs BIO vs TMO
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Medical - Instruments & Supplies
Medical - Devices
Medical - Diagnostics & Research
NNNN vs QDEL vs HOLX vs BIO vs TMO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Devices | Medical - Diagnostics & Research |
| Market Cap | $1.13B | $737M | $16.97B | $6.87B | $172.80B |
| Revenue (TTM) | $16M | $2.66B | $4.13B | $2.59B | $45.20B |
| Net Income (TTM) | $5M | $-1.21B | $544M | $169M | $6.86B |
| Gross Margin | 62.1% | 56.6% | 52.8% | 51.9% | 39.4% |
| Operating Margin | 26.5% | -37.0% | 17.5% | 9.2% | 17.8% |
| Forward P/E | 461.4x | 6.0x | 17.2x | 27.4x | 18.7x |
| Total Debt | $0.00 | $2.80B | $2.63B | $1.53B | $40.85B |
| Cash & Equiv. | $12M | $170M | $1.96B | $532M | $9.86B |
NNNN vs QDEL vs HOLX vs BIO vs TMO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 25 | May 26 | Return |
|---|---|---|---|
| Anbio Biotechnology… (NNNN) | 100 | 386.2 | +286.2% |
| QuidelOrtho Corpora… (QDEL) | 100 | 27.1 | -72.9% |
| Hologic, Inc. (HOLX) | 100 | 119.2 | +19.2% |
| Bio-Rad Laboratorie… (BIO) | 100 | 95.9 | -4.1% |
| Thermo Fisher Scien… (TMO) | 100 | 87.9 | -12.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NNNN vs QDEL vs HOLX vs BIO vs TMO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NNNN carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 21.9%, EPS growth 366.7%, 3Y rev CAGR 22.7%
- 347.8% 10Y total return vs TMO's 222.6%
- Beta 0.46, current ratio 10.71x
- 21.9% revenue growth vs QDEL's -1.9%
QDEL is the #2 pick in this set and the best alternative if value is your priority.
- Lower P/E (6.0x vs 18.7x)
HOLX ranks third and is worth considering specifically for sleep-well-at-night.
- Lower volatility, beta 0.45, Low D/E 52.0%, current ratio 3.75x
- Beta 0.45 vs QDEL's 2.28, lower leverage
Among these 5 stocks, BIO doesn't own a clear edge in any measured category.
TMO is the clearest fit if your priority is income & stability.
- Dividend streak 8 yrs, beta 1.07, yield 0.4%
- 0.4% yield; 8-year raise streak; the other 4 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 21.9% revenue growth vs QDEL's -1.9% | |
| Value | Lower P/E (6.0x vs 18.7x) | |
| Quality / Margins | 31.0% margin vs QDEL's -45.6% | |
| Stability / Safety | Beta 0.45 vs QDEL's 2.28, lower leverage | |
| Dividends | 0.4% yield; 8-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +289.7% vs QDEL's -70.3% | |
| Efficiency (ROA) | 26.4% ROA vs QDEL's -20.7%, ROIC 28.3% vs -13.6% |
NNNN vs QDEL vs HOLX vs BIO vs TMO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
NNNN vs QDEL vs HOLX vs BIO vs TMO — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NNNN leads in 3 of 6 categories
QDEL leads 1 • HOLX leads 1 • TMO leads 1 • BIO leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
NNNN leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
TMO is the larger business by revenue, generating $45.2B annually — 2805.9x NNNN's $16M. NNNN is the more profitable business, keeping 31.0% of every revenue dollar as net income compared to QDEL's -45.6%. On growth, TMO holds the edge at +6.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $16M | $2.7B | $4.1B | $2.6B | $45.2B |
| EBITDAEarnings before interest/tax | $5M | -$649M | $974M | -$315M | $10.5B |
| Net IncomeAfter-tax profit | $5M | -$1.2B | $544M | $169M | $6.9B |
| Free Cash FlowCash after capex | $3M | -$75M | $1000M | $357M | $6.7B |
| Gross MarginGross profit ÷ Revenue | +62.1% | +56.6% | +52.8% | +51.9% | +39.4% |
| Operating MarginEBIT ÷ Revenue | +26.5% | -37.0% | +17.5% | +9.2% | +17.8% |
| Net MarginNet income ÷ Revenue | +31.0% | -45.6% | +13.2% | +6.5% | +15.2% |
| FCF MarginFCF ÷ Revenue | +20.0% | -2.8% | +24.2% | +13.8% | +14.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | -36.0% | -10.5% | +2.5% | +1.1% | +6.2% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.7% | -6.1% | -9.2% | -9.5% | +11.3% |
Valuation Metrics
QDEL leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 9.1x trailing earnings, BIO trades at a 98% valuation discount to NNNN's 461.4x P/E. On an enterprise value basis, BIO's 16.5x EV/EBITDA is more attractive than NNNN's 437.3x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.1B | $737M | $17.0B | $6.9B | $172.8B |
| Enterprise ValueMkt cap + debt − cash | $1.1B | $3.4B | $17.6B | $7.9B | $203.8B |
| Trailing P/EPrice ÷ TTM EPS | 461.43x | -0.65x | 30.53x | 9.13x | 26.21x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 5.96x | 17.21x | 27.40x | 18.71x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 12.41x |
| EV / EBITDAEnterprise value multiple | 437.29x | — | 17.39x | 16.53x | 18.72x |
| Price / SalesMarket cap ÷ Revenue | 138.56x | 0.27x | 4.14x | 2.66x | 3.88x |
| Price / BookPrice ÷ Book value/share | 63.57x | 0.38x | 3.43x | 0.93x | 3.27x |
| Price / FCFMarket cap ÷ FCF | 545.16x | — | 18.44x | 18.33x | 27.46x |
Profitability & Efficiency
NNNN leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
NNNN delivers a 29.1% return on equity — every $100 of shareholder capital generates $29 in annual profit, vs $-56 for QDEL. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to QDEL's 1.46x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs BIO's 5/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +29.1% | -56.3% | +11.0% | +2.4% | +13.2% |
| ROA (TTM)Return on assets | +26.4% | -20.7% | +6.1% | +2.2% | +6.4% |
| ROICReturn on invested capital | +28.3% | -13.6% | +9.4% | +2.6% | +7.5% |
| ROCEReturn on capital employed | +12.5% | -18.0% | +8.8% | +2.9% | +9.1% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 6 | 7 | 5 | 6 |
| Debt / EquityFinancial leverage | — | 1.46x | 0.52x | 0.21x | 0.76x |
| Net DebtTotal debt minus cash | -$12M | $2.6B | $667M | $999M | $31.0B |
| Cash & Equiv.Liquid assets | $12M | $170M | $2.0B | $532M | $9.9B |
| Total DebtShort + long-term debt | $0 | $2.8B | $2.6B | $1.5B | $40.9B |
| Interest CoverageEBIT ÷ Interest expense | — | -5.18x | 8.00x | -2.49x | 5.89x |
Total Returns (Dividends Reinvested)
NNNN leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NNNN five years ago would be worth $44,783 today (with dividends reinvested), compared to $930 for QDEL. Over the past 12 months, NNNN leads with a +289.7% total return vs QDEL's -70.3%. The 3-year compound annual growth rate (CAGR) favors NNNN at 64.8% vs QDEL's -50.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -12.3% | -62.4% | +1.9% | -16.7% | -21.4% |
| 1-Year ReturnPast 12 months | +289.7% | -70.3% | +35.3% | +5.5% | +13.6% |
| 3-Year ReturnCumulative with dividends | +347.8% | -87.7% | -8.5% | -32.8% | -13.4% |
| 5-Year ReturnCumulative with dividends | +347.8% | -90.7% | +16.8% | -57.9% | +1.9% |
| 10-Year ReturnCumulative with dividends | +347.8% | -34.6% | +124.3% | +79.3% | +222.6% |
| CAGR (3Y)Annualised 3-year return | +64.8% | -50.3% | -2.9% | -12.4% | -4.7% |
Risk & Volatility
HOLX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HOLX is the less volatile stock with a 0.45 beta — it tends to amplify market swings less than QDEL's 2.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs QDEL's 27.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.46x | 2.28x | 0.45x | 0.91x | 1.07x |
| 52-Week HighHighest price in past year | $55.65 | $38.99 | $76.04 | $343.12 | $643.99 |
| 52-Week LowLowest price in past year | $6.34 | $10.22 | $53.62 | $211.43 | $385.46 |
| % of 52W HighCurrent price vs 52-week peak | +46.4% | +27.8% | +100.0% | +74.1% | +72.2% |
| RSI (14)Momentum oscillator 0–100 | 44.1 | 34.5 | 69.1 | 36.1 | 43.9 |
| Avg Volume (50D)Average daily shares traded | 34K | 2.2M | 10.3M | 304K | 1.9M |
Analyst Outlook
TMO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: QDEL as "Hold", HOLX as "Hold", BIO as "Buy", TMO as "Buy". Consensus price targets imply 40.8% upside for TMO (target: $655) vs 3.9% for HOLX (target: $79). TMO is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Hold | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $12.25 | $79.00 | $312.50 | $654.67 |
| # AnalystsCovering analysts | — | 15 | 42 | 14 | 42 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +0.4% |
| Dividend StreakConsecutive years of raises | — | 0 | — | — | 8 |
| Dividend / ShareAnnual DPS | — | — | — | — | $1.69 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +4.4% | +4.3% | +1.7% |
NNNN leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). QDEL leads in 1 (Valuation Metrics).
NNNN vs QDEL vs HOLX vs BIO vs TMO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is NNNN or QDEL or HOLX or BIO or TMO a better buy right now?
For growth investors, Anbio Biotechnology Class A Ordinary Shares (NNNN) is the stronger pick with 21.
9% revenue growth year-over-year, versus -1. 9% for QuidelOrtho Corporation (QDEL). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 1x trailing P/E (27. 4x forward), making it the more compelling value choice. Analysts rate Bio-Rad Laboratories, Inc. (BIO) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — NNNN or QDEL or HOLX or BIO or TMO?
On trailing P/E, Bio-Rad Laboratories, Inc.
(BIO) is the cheapest at 9. 1x versus Anbio Biotechnology Class A Ordinary Shares at 461. 4x. On forward P/E, QuidelOrtho Corporation is actually cheaper at 6. 0x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — NNNN or QDEL or HOLX or BIO or TMO?
Over the past 5 years, Anbio Biotechnology Class A Ordinary Shares (NNNN) delivered a total return of +347.
8%, compared to -90. 7% for QuidelOrtho Corporation (QDEL). Over 10 years, the gap is even starker: NNNN returned +347. 8% versus QDEL's -34. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — NNNN or QDEL or HOLX or BIO or TMO?
By beta (market sensitivity over 5 years), Hologic, Inc.
(HOLX) is the lower-risk stock at 0. 45β versus QuidelOrtho Corporation's 2. 28β — meaning QDEL is approximately 403% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 146% for QuidelOrtho Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — NNNN or QDEL or HOLX or BIO or TMO?
By revenue growth (latest reported year), Anbio Biotechnology Class A Ordinary Shares (NNNN) is pulling ahead at 21.
9% versus -1. 9% for QuidelOrtho Corporation (QDEL). On earnings-per-share growth, the picture is similar: Anbio Biotechnology Class A Ordinary Shares grew EPS 366. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, NNNN leads at 22. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — NNNN or QDEL or HOLX or BIO or TMO?
Bio-Rad Laboratories, Inc.
(BIO) is the more profitable company, earning 29. 4% net margin versus -41. 5% for QuidelOrtho Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NNNN leads at 24. 4% versus -33. 7% for QDEL. At the gross margin level — before operating expenses — NNNN leads at 71. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is NNNN or QDEL or HOLX or BIO or TMO more undervalued right now?
On forward earnings alone, QuidelOrtho Corporation (QDEL) trades at 6.
0x forward P/E versus 27. 4x for Bio-Rad Laboratories, Inc. — 21. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for TMO: 40. 8% to $654. 67.
08Which pays a better dividend — NNNN or QDEL or HOLX or BIO or TMO?
In this comparison, TMO (0.
4% yield) pays a dividend. NNNN, QDEL, HOLX, BIO do not pay a meaningful dividend and should not be held primarily for income.
09Is NNNN or QDEL or HOLX or BIO or TMO better for a retirement portfolio?
For long-horizon retirement investors, Anbio Biotechnology Class A Ordinary Shares (NNNN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
46), +347. 8% 10Y return). QuidelOrtho Corporation (QDEL) carries a higher beta of 2. 28 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NNNN: +347. 8%, QDEL: -34. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between NNNN and QDEL and HOLX and BIO and TMO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: NNNN is a small-cap high-growth stock; QDEL is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock; TMO is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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