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Stock Comparison

NUWE vs DBVT vs ALKS vs NVCR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NUWE
Nuwellis, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-100.0%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-59.3%
ALKS
Alkermes plc

Biotechnology

HealthcareNASDAQ • IE
Market Cap$5.90B
5Y Perf.+113.9%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-73.5%

NUWE vs DBVT vs ALKS vs NVCR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NUWE logoNUWE
DBVT logoDBVT
ALKS logoALKS
NVCR logoNVCR
IndustryMedical - DevicesBiotechnologyBiotechnologyMedical - Instruments & Supplies
Market Cap$2M$1712.35T$5.90B$1.92B
Revenue (TTM)$8M$0.00$1.56B$674M
Net Income (TTM)$-18M$-168M$153M$-173M
Gross Margin62.0%65.4%75.2%
Operating Margin-134.3%12.3%-27.2%
Forward P/E24.8x
Total Debt$328K$22M$70M$290M
Cash & Equiv.$1M$194M$1.12B$103M

NUWE vs DBVT vs ALKS vs NVCRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NUWE
DBVT
ALKS
NVCR
StockMay 20May 26Return
Nuwellis, Inc. (NUWE)1000.0-100.0%
DBV Technologies S.… (DBVT)10040.7-59.3%
Alkermes plc (ALKS)100213.9+113.9%
NovoCure Limited (NVCR)10026.5-73.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: NUWE vs DBVT vs ALKS vs NVCR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ALKS leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. DBV Technologies S.A. is the stronger pick specifically for recent price momentum and sentiment. NVCR also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
NUWE
Nuwellis, Inc.
The Secondary Option

NUWE lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
DBVT
DBV Technologies S.A.
The Income Pick

DBVT is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 0 yrs, beta 1.26
  • +110.4% vs NUWE's -97.2%
Best for: income & stability
ALKS
Alkermes plc
The Long-Run Compounder

ALKS carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.

  • -11.0% 10Y total return vs NVCR's 30.3%
  • Lower volatility, beta 1.06, Low D/E 3.8%, current ratio 3.55x
  • Beta 1.06, current ratio 3.55x
  • 9.8% margin vs NUWE's -211.9%
Best for: long-term compounding and sleep-well-at-night
NVCR
NovoCure Limited
The Growth Play

NVCR is the clearest fit if your priority is growth exposure.

  • Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
  • 8.3% revenue growth vs DBVT's -100.0%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNVCR logoNVCR8.3% revenue growth vs DBVT's -100.0%
Quality / MarginsALKS logoALKS9.8% margin vs NUWE's -211.9%
Stability / SafetyALKS logoALKSBeta 1.06 vs NVCR's 2.20, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)DBVT logoDBVT+110.4% vs NUWE's -97.2%
Efficiency (ROA)ALKS logoALKS5.4% ROA vs NUWE's -231.2%, ROIC 18.9% vs -433.0%

NUWE vs DBVT vs ALKS vs NVCR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NUWENuwellis, Inc.

Segment breakdown not available.

DBVTDBV Technologies S.A.

Segment breakdown not available.

ALKSAlkermes plc
FY 2025
Vivitrol
39.8%$468M
Aristada And Aristada Initio
31.5%$370M
Manufactured Product And Royalty
24.8%$291M
Manufacturing Revenue
3.9%$46M
NVCRNovoCure Limited

Segment breakdown not available.

NUWE vs DBVT vs ALKS vs NVCR — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLALKSLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

ALKS leads this category, winning 4 of 6 comparable metrics.

ALKS and DBVT operate at a comparable scale, with $1.6B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to NUWE's -2.1%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
RevenueTrailing 12 months$8M$0$1.6B$674M
EBITDAEarnings before interest/tax-$8M-$112M$212M-$165M
Net IncomeAfter-tax profit-$18M-$168M$153M-$173M
Free Cash FlowCash after capex-$11M-$151M$392M-$48M
Gross MarginGross profit ÷ Revenue+62.0%+65.4%+75.2%
Operating MarginEBIT ÷ Revenue-134.3%+12.3%-27.2%
Net MarginNet income ÷ Revenue-2.1%+9.8%-25.7%
FCF MarginFCF ÷ Revenue-131.8%+25.1%-7.1%
Rev. Growth (YoY)Latest quarter vs prior year+4.4%+28.2%+12.3%
EPS Growth (YoY)Latest quarter vs prior year-2.4%+91.5%-4.1%-100.0%
ALKS leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — NUWE and DBVT and NVCR each lead in 1 of 3 comparable metrics.
MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
Market CapShares × price$2M$1712.35T$5.9B$1.9B
Enterprise ValueMkt cap + debt − cash$1M$1712.35T$4.9B$2.1B
Trailing P/EPrice ÷ TTM EPS-0.04x-0.76x24.76x-13.80x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple17.25x
Price / SalesMarket cap ÷ Revenue0.22x4.00x2.92x
Price / BookPrice ÷ Book value/share2.89x0.66x3.28x5.51x
Price / FCFMarket cap ÷ FCF12.28x
Evenly matched — NUWE and DBVT and NVCR each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

ALKS leads this category, winning 8 of 9 comparable metrics.

ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-60 for NUWE. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs NUWE's 3/9, reflecting strong financial health.

MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
ROE (TTM)Return on equity-60.5%-130.2%+8.8%-50.8%
ROA (TTM)Return on assets-2.3%-89.0%+5.4%-16.5%
ROICReturn on invested capital-4.3%+18.9%-16.4%
ROCEReturn on capital employed-2.1%-145.7%+14.2%-28.9%
Piotroski ScoreFundamental quality 0–93475
Debt / EquityFinancial leverage0.13x0.13x0.04x0.85x
Net DebtTotal debt minus cash-$757,000-$172M-$1.0B$187M
Cash & Equiv.Liquid assets$1M$194M$1.1B$103M
Total DebtShort + long-term debt$328,000$22M$70M$290M
Interest CoverageEBIT ÷ Interest expense-0.75x-189.82x32.30x-96.80x
ALKS leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

DBVT leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ALKS five years ago would be worth $16,091 today (with dividends reinvested), compared to $0 for NUWE. Over the past 12 months, DBVT leads with a +110.4% total return vs NUWE's -97.2%. The 3-year compound annual growth rate (CAGR) favors DBVT at 6.2% vs NUWE's -94.5% — a key indicator of consistent wealth creation.

MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
YTD ReturnYear-to-date-39.2%+4.9%+25.3%+28.3%
1-Year ReturnPast 12 months-97.2%+110.4%+16.5%+1.1%
3-Year ReturnCumulative with dividends-100.0%+19.7%+14.5%-75.7%
5-Year ReturnCumulative with dividends-100.0%-69.1%+60.9%-91.3%
10-Year ReturnCumulative with dividends-100.0%-87.0%-11.0%+30.3%
CAGR (3Y)Annualised 3-year return-94.5%+6.2%+4.6%-37.6%
DBVT leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

ALKS leads this category, winning 2 of 2 comparable metrics.

ALKS is the less volatile stock with a 1.06 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs NUWE's 2.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
Beta (5Y)Sensitivity to S&P 5001.00x1.26x1.00x2.15x
52-Week HighHighest price in past year$43.26$26.18$36.60$20.06
52-Week LowLowest price in past year$0.96$7.53$25.17$9.82
% of 52W HighCurrent price vs 52-week peak+2.5%+76.3%+96.7%+83.9%
RSI (14)Momentum oscillator 0–10041.848.160.269.8
Avg Volume (50D)Average daily shares traded61K252K2.3M1.5M
ALKS leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: DBVT as "Buy", ALKS as "Buy", NVCR as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 29.9% for ALKS (target: $46).

MetricNUWE logoNUWENuwellis, Inc.DBVT logoDBVTDBV Technologies …ALKS logoALKSAlkermes plcNVCR logoNVCRNovoCure Limited
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$46.33$46.00$33.50
# AnalystsCovering analysts152815
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.5%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ALKS leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). DBVT leads in 1 (Total Returns). 1 tied.

Best OverallAlkermes plc (ALKS)Leads 3 of 6 categories
Loading custom metrics...

NUWE vs DBVT vs ALKS vs NVCR: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is NUWE or DBVT or ALKS or NVCR a better buy right now?

For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.

3% revenue growth year-over-year, versus -5. 4% for Nuwellis, Inc. (NUWE). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — NUWE or DBVT or ALKS or NVCR?

Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +60.

9%, compared to -100. 0% for Nuwellis, Inc. (NUWE). Over 10 years, the gap is even starker: NVCR returned +38. 5% versus NUWE's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — NUWE or DBVT or ALKS or NVCR?

By beta (market sensitivity over 5 years), Alkermes plc (ALKS) is the lower-risk stock at 1.

00β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 115% more volatile than ALKS relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.

04

Which is growing faster — NUWE or DBVT or ALKS or NVCR?

By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.

3% versus -5. 4% for Nuwellis, Inc. (NUWE). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALKS leads at 9. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — NUWE or DBVT or ALKS or NVCR?

Alkermes plc (ALKS) is the more profitable company, earning 16.

4% net margin versus -211. 8% for Nuwellis, Inc. — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALKS leads at 17. 2% versus -134. 3% for NUWE. At the gross margin level — before operating expenses — ALKS leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — NUWE or DBVT or ALKS or NVCR?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is NUWE or DBVT or ALKS or NVCR better for a retirement portfolio?

For long-horizon retirement investors, Alkermes plc (ALKS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.

00)). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ALKS: -12. 0%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between NUWE and DBVT and ALKS and NVCR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.

Stocks Like

NUWE

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 37%
Run This Screen
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DBVT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
Run This Screen
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ALKS

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 14%
  • Net Margin > 5%
Run This Screen
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NVCR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 45%
Run This Screen

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