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Stock Comparison

OCUL vs KALA vs RCKT vs LNTH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
OCUL
Ocular Therapeutix, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.12B
5Y Perf.+37.5%
KALA
KALA BIO, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$618K
5Y Perf.-100.0%
RCKT
Rocket Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$398M
5Y Perf.-80.5%
LNTH
Lantheus Holdings, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$5.92B
5Y Perf.+562.8%

OCUL vs KALA vs RCKT vs LNTH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
OCUL logoOCUL
KALA logoKALA
RCKT logoRCKT
LNTH logoLNTH
IndustryBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - Specialty & Generic
Market Cap$2.12B$618K$398M$5.92B
Revenue (TTM)$52M$254K$0.00$1.55B
Net Income (TTM)$-290M$-36M$-223M$279M
Gross Margin87.2%-3.1%60.5%
Operating Margin-5.8%-150.6%18.8%
Forward P/E17.5x
Total Debt$80M$32M$25M$738K
Cash & Equiv.$737M$51M$78M$359M

OCUL vs KALA vs RCKT vs LNTHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

OCUL
KALA
RCKT
LNTH
StockMay 20May 26Return
Ocular Therapeutix,… (OCUL)100137.5+37.5%
KALA BIO, Inc. (KALA)1000.0-100.0%
Rocket Pharmaceutic… (RCKT)10019.5-80.5%
Lantheus Holdings, … (LNTH)100662.8+562.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: OCUL vs KALA vs RCKT vs LNTH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LNTH leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Ocular Therapeutix, Inc. is the stronger pick specifically for recent price momentum and sentiment. KALA also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
OCUL
Ocular Therapeutix, Inc.
The Defensive Pick

OCUL is the #2 pick in this set and the best alternative if defensive is your priority.

  • Beta 1.27, current ratio 15.39x
  • +37.3% vs KALA's -97.6%
Best for: defensive
KALA
KALA BIO, Inc.
The Growth Play

KALA is the clearest fit if your priority is growth exposure.

  • Rev growth 262.9%, EPS growth 59.8%
  • 262.9% revenue growth vs OCUL's -18.7%
Best for: growth exposure
RCKT
Rocket Pharmaceuticals, Inc.
The Secondary Option

RCKT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
LNTH
Lantheus Holdings, Inc.
The Income Pick

LNTH carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 0 yrs, beta 0.47
  • 41.9% 10Y total return vs OCUL's -10.6%
  • Lower volatility, beta 0.47, Low D/E 0.1%, current ratio 2.70x
  • 18.0% margin vs KALA's -141.1%
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthKALA logoKALA262.9% revenue growth vs OCUL's -18.7%
Quality / MarginsLNTH logoLNTH18.0% margin vs KALA's -141.1%
Stability / SafetyLNTH logoLNTHBeta 0.47 vs KALA's 2.09, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)OCUL logoOCUL+37.3% vs KALA's -97.6%
Efficiency (ROA)LNTH logoLNTH12.4% ROA vs KALA's -143.2%

OCUL vs KALA vs RCKT vs LNTH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

OCULOcular Therapeutix, Inc.
FY 2025
Product
99.8%$52M
Collaboration revenue
0.2%$128,000
KALAKALA BIO, Inc.

Segment breakdown not available.

RCKTRocket Pharmaceuticals, Inc.

Segment breakdown not available.

LNTHLantheus Holdings, Inc.
FY 2025
Product
33.4%$1.5B
Radiopharmaceutical Oncology
21.9%$989M
PYLARIFY
21.9%$989M
Total Precision Diagnostics
10.9%$493M
DEFINITY
7.3%$330M
Techne Lite
1.9%$87M
Strategic Partnerships And Other
1.3%$59M
Other (2)
1.3%$59M

OCUL vs KALA vs RCKT vs LNTH — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLNTHLAGGINGRCKT

Income & Cash Flow (Last 12 Months)

LNTH leads this category, winning 5 of 6 comparable metrics.

LNTH and RCKT operate at a comparable scale, with $1.5B and $0 in trailing revenue. LNTH is the more profitable business, keeping 18.0% of every revenue dollar as net income compared to KALA's -141.1%.

MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
RevenueTrailing 12 months$52M$254,000$0$1.5B
EBITDAEarnings before interest/tax-$295M-$38M-$232M$347M
Net IncomeAfter-tax profit-$290M-$36M-$223M$279M
Free Cash FlowCash after capex-$241M-$32M-$190M$372M
Gross MarginGross profit ÷ Revenue+87.2%-3.1%+60.5%
Operating MarginEBIT ÷ Revenue-5.8%-150.6%+18.8%
Net MarginNet income ÷ Revenue-5.6%-141.1%+18.0%
FCF MarginFCF ÷ Revenue-4.6%-126.3%+24.0%
Rev. Growth (YoY)Latest quarter vs prior year+0.8%+1.2%
EPS Growth (YoY)Latest quarter vs prior year-5.3%+44.6%+38.7%+76.5%
LNTH leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — OCUL and KALA and LNTH each lead in 1 of 3 comparable metrics.
MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
Market CapShares × price$2.1B$617,676$398M$5.9B
Enterprise ValueMkt cap + debt − cash$1.5B-$18M$345M$5.6B
Trailing P/EPrice ÷ TTM EPS-6.82x-0.01x-1.83x26.69x
Forward P/EPrice ÷ next-FY EPS est.17.52x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple14.61x
Price / SalesMarket cap ÷ Revenue40.90x3.84x
Price / BookPrice ÷ Book value/share2.77x0.04x1.47x5.72x
Price / FCFMarket cap ÷ FCF16.73x
Evenly matched — OCUL and KALA and LNTH each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

LNTH leads this category, winning 8 of 9 comparable metrics.

LNTH delivers a 24.3% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-4 for KALA. LNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KALA's 2.62x. On the Piotroski fundamental quality scale (0–9), LNTH scores 5/9 vs RCKT's 1/9, reflecting solid financial health.

MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
ROE (TTM)Return on equity-64.6%-3.9%-80.5%+24.3%
ROA (TTM)Return on assets-48.4%-143.2%-67.5%+12.4%
ROICReturn on invested capital-63.2%+30.6%
ROCEReturn on capital employed-46.0%-95.2%-58.9%+17.1%
Piotroski ScoreFundamental quality 0–94215
Debt / EquityFinancial leverage0.12x2.62x0.09x0.00x
Net DebtTotal debt minus cash-$657M-$19M-$53M-$358M
Cash & Equiv.Liquid assets$737M$51M$78M$359M
Total DebtShort + long-term debt$80M$32M$25M$738,000
Interest CoverageEBIT ÷ Interest expense-24.63x-6.92x11.72x
LNTH leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — OCUL and LNTH each lead in 3 of 6 comparable metrics.

A $10,000 investment in LNTH five years ago would be worth $41,420 today (with dividends reinvested), compared to $3 for KALA. Over the past 12 months, OCUL leads with a +37.3% total return vs KALA's -97.6%. The 3-year compound annual growth rate (CAGR) favors OCUL at 14.8% vs KALA's -82.6% — a key indicator of consistent wealth creation.

MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
YTD ReturnYear-to-date-18.1%-86.6%+6.1%+35.3%
1-Year ReturnPast 12 months+37.3%-97.6%-45.2%+13.1%
3-Year ReturnCumulative with dividends+51.2%-99.5%-82.8%-4.0%
5-Year ReturnCumulative with dividends-40.4%-100.0%-91.6%+314.2%
10-Year ReturnCumulative with dividends-10.6%-100.0%-91.3%+4192.5%
CAGR (3Y)Annualised 3-year return+14.8%-82.6%-44.4%-1.4%
Evenly matched — OCUL and LNTH each lead in 3 of 6 comparable metrics.

Risk & Volatility

LNTH leads this category, winning 2 of 2 comparable metrics.

LNTH is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than KALA's 2.09 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LNTH currently trades 97.8% from its 52-week high vs KALA's 0.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
Beta (5Y)Sensitivity to S&P 5001.27x2.09x1.31x0.47x
52-Week HighHighest price in past year$16.44$20.60$7.39$93.00
52-Week LowLowest price in past year$6.23$0.08$2.19$47.25
% of 52W HighCurrent price vs 52-week peak+58.9%+0.4%+49.7%+97.8%
RSI (14)Momentum oscillator 0–10058.330.154.461.2
Avg Volume (50D)Average daily shares traded4.0M9.2M3.5M886K
LNTH leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: OCUL as "Buy", KALA as "Buy", RCKT as "Buy", LNTH as "Buy". Consensus price targets imply 21861.5% upside for KALA (target: $18) vs 11.0% for LNTH (target: $101).

MetricOCUL logoOCULOcular Therapeuti…KALA logoKALAKALA BIO, Inc.RCKT logoRCKTRocket Pharmaceut…LNTH logoLNTHLantheus Holdings…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$25.50$18.25$5.00$101.00
# AnalystsCovering analysts1891917
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+5.1%
Insufficient data to determine a leader in this category.
Key Takeaway

LNTH leads in 3 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 2 categories are tied.

Best OverallLantheus Holdings, Inc. (LNTH)Leads 3 of 6 categories
Loading custom metrics...

OCUL vs KALA vs RCKT vs LNTH: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is OCUL or KALA or RCKT or LNTH a better buy right now?

For growth investors, Lantheus Holdings, Inc.

(LNTH) is the stronger pick with 0. 5% revenue growth year-over-year, versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). Lantheus Holdings, Inc. (LNTH) offers the better valuation at 26. 7x trailing P/E (17. 5x forward), making it the more compelling value choice. Analysts rate Ocular Therapeutix, Inc. (OCUL) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — OCUL or KALA or RCKT or LNTH?

Over the past 5 years, Lantheus Holdings, Inc.

(LNTH) delivered a total return of +314. 2%, compared to -100. 0% for KALA BIO, Inc. (KALA). Over 10 years, the gap is even starker: LNTH returned +41. 9% versus KALA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — OCUL or KALA or RCKT or LNTH?

By beta (market sensitivity over 5 years), Lantheus Holdings, Inc.

(LNTH) is the lower-risk stock at 0. 47β versus KALA BIO, Inc. 's 2. 09β — meaning KALA is approximately 346% more volatile than LNTH relative to the S&P 500. On balance sheet safety, Lantheus Holdings, Inc. (LNTH) carries a lower debt/equity ratio of 0% versus 3% for KALA BIO, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — OCUL or KALA or RCKT or LNTH?

By revenue growth (latest reported year), Lantheus Holdings, Inc.

(LNTH) is pulling ahead at 0. 5% versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). On earnings-per-share growth, the picture is similar: KALA BIO, Inc. grew EPS 59. 8% year-over-year, compared to -21. 8% for Lantheus Holdings, Inc.. Over a 3-year CAGR, LNTH leads at 18. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — OCUL or KALA or RCKT or LNTH?

Lantheus Holdings, Inc.

(LNTH) is the more profitable company, earning 15. 2% net margin versus -141. 1% for KALA BIO, Inc. — meaning it keeps 15. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LNTH leads at 20. 2% versus -150. 6% for KALA. At the gross margin level — before operating expenses — OCUL leads at 87. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is OCUL or KALA or RCKT or LNTH more undervalued right now?

Analyst consensus price targets imply the most upside for KALA: 21861.

5% to $18. 25.

07

Which pays a better dividend — OCUL or KALA or RCKT or LNTH?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is OCUL or KALA or RCKT or LNTH better for a retirement portfolio?

For long-horizon retirement investors, Lantheus Holdings, Inc.

(LNTH) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 47)). KALA BIO, Inc. (KALA) carries a higher beta of 2. 09 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LNTH: +41. 9%, KALA: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between OCUL and KALA and RCKT and LNTH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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OCUL

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  • Market Cap > $100B
  • Gross Margin > 52%
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