Medical - Devices
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4 / 10Stock Comparison
OFIX vs GMED vs SYK vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Medical - Devices
Medical - Instruments & Supplies
OFIX vs GMED vs SYK vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Devices | Medical - Devices | Medical - Devices | Medical - Instruments & Supplies |
| Market Cap | $488M | $11.51B | $112.69B | $1.92B |
| Revenue (TTM) | $825M | $3.10B | $25.12B | $674M |
| Net Income (TTM) | $-60M | $587M | $3.25B | $-173M |
| Gross Margin | 69.0% | 50.9% | 63.5% | 75.2% |
| Operating Margin | -4.0% | 17.2% | 22.4% | -27.2% |
| Forward P/E | — | 19.0x | 19.6x | — |
| Total Debt | $229M | $119M | $14.86B | $290M |
| Cash & Equiv. | $82M | $526M | $4.01B | $103M |
OFIX vs GMED vs SYK vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Orthofix Medical In… (OFIX) | 100 | 35.4 | -64.6% |
| Globus Medical, Inc. (GMED) | 100 | 155.7 | +55.7% |
| Stryker Corporation (SYK) | 100 | 150.3 | +50.3% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OFIX vs GMED vs SYK vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
OFIX plays a supporting role in this comparison — it may shine differently against other peers.
GMED carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 16.7%, EPS growth 422.7%, 3Y rev CAGR 42.2%
- 264.4% 10Y total return vs SYK's 187.1%
- Lower volatility, beta 1.29, Low D/E 2.6%, current ratio 4.26x
- PEG 0.61 vs SYK's 1.32
SYK is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 34 yrs, beta 0.55, yield 1.1%
- Beta 0.55 vs NVCR's 2.20, lower leverage
- 1.1% yield; 34-year raise streak; the other 3 pay no meaningful dividend
NVCR lags the leaders in this set but could rank higher in a more targeted comparison.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 16.7% revenue growth vs OFIX's 2.9% | |
| Value | Better valuation composite | |
| Quality / Margins | 18.9% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 0.55 vs NVCR's 2.20, lower leverage | |
| Dividends | 1.1% yield; 34-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +19.0% vs SYK's -22.5% | |
| Efficiency (ROA) | 11.3% ROA vs NVCR's -16.5%, ROIC 8.9% vs -16.4% |
OFIX vs GMED vs SYK vs NVCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
OFIX vs GMED vs SYK vs NVCR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
GMED leads in 4 of 6 categories
OFIX leads 0 • SYK leads 0 • NVCR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
GMED leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SYK is the larger business by revenue, generating $25.1B annually — 37.2x NVCR's $674M. GMED is the more profitable business, keeping 18.9% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, GMED holds the edge at +27.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $825M | $3.1B | $25.1B | $674M |
| EBITDAEarnings before interest/tax | $102M | $745M | $6.3B | -$165M |
| Net IncomeAfter-tax profit | -$60M | $587M | $3.2B | -$173M |
| Free Cash FlowCash after capex | -$4M | $605M | $4.3B | -$48M |
| Gross MarginGross profit ÷ Revenue | +69.0% | +50.9% | +63.5% | +75.2% |
| Operating MarginEBIT ÷ Revenue | -4.0% | +17.2% | +22.4% | -27.2% |
| Net MarginNet income ÷ Revenue | -7.3% | +18.9% | +12.9% | -25.7% |
| FCF MarginFCF ÷ Revenue | -0.4% | +19.5% | +17.1% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +1.6% | +27.0% | +11.4% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +61.5% | +66.7% | +56.0% | -100.0% |
Valuation Metrics
GMED leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 21.7x trailing earnings, GMED trades at a 38% valuation discount to SYK's 35.0x P/E. Adjusting for growth (PEG ratio), GMED offers better value at 0.70x vs SYK's 2.36x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $488M | $11.5B | $112.7B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $635M | $11.1B | $123.5B | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | -5.29x | 21.70x | 35.03x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 19.03x | 19.62x | — |
| PEG RatioP/E ÷ EPS growth rate | — | 0.70x | 2.36x | — |
| EV / EBITDAEnterprise value multiple | — | 18.51x | 20.31x | — |
| Price / SalesMarket cap ÷ Revenue | 0.59x | 3.92x | 4.49x | 2.92x |
| Price / BookPrice ÷ Book value/share | 1.07x | 2.55x | 5.02x | 5.51x |
| Price / FCFMarket cap ÷ FCF | — | 19.54x | 26.31x | — |
Profitability & Efficiency
GMED leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
SYK delivers a 15.0% return on equity — every $100 of shareholder capital generates $15 in annual profit, vs $-51 for NVCR. GMED carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), GMED scores 9/9 vs OFIX's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -13.4% | +13.0% | +15.0% | -50.8% |
| ROA (TTM)Return on assets | -7.0% | +11.3% | +6.9% | -16.5% |
| ROICReturn on invested capital | -8.6% | +8.9% | +11.4% | -16.4% |
| ROCEReturn on capital employed | -9.7% | +10.4% | +13.0% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 9 | 6 | 5 |
| Debt / EquityFinancial leverage | 0.51x | 0.03x | 0.66x | 0.85x |
| Net DebtTotal debt minus cash | $147M | -$408M | $10.8B | $187M |
| Cash & Equiv.Liquid assets | $82M | $526M | $4.0B | $103M |
| Total DebtShort + long-term debt | $229M | $119M | $14.9B | $290M |
| Interest CoverageEBIT ÷ Interest expense | -4.97x | 81.13x | 6.72x | -96.80x |
Total Returns (Dividends Reinvested)
GMED leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in SYK five years ago would be worth $12,152 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, GMED leads with a +19.0% total return vs SYK's -22.5%. The 3-year compound annual growth rate (CAGR) favors GMED at 13.5% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -18.7% | -2.5% | -15.2% | +28.3% |
| 1-Year ReturnPast 12 months | +0.4% | +19.0% | -22.5% | +1.1% |
| 3-Year ReturnCumulative with dividends | -35.1% | +46.3% | +5.5% | -75.7% |
| 5-Year ReturnCumulative with dividends | -72.7% | +16.1% | +21.5% | -91.3% |
| 10-Year ReturnCumulative with dividends | -72.0% | +264.4% | +187.1% | +30.3% |
| CAGR (3Y)Annualised 3-year return | -13.4% | +13.5% | +1.8% | -37.6% |
Risk & Volatility
Evenly matched — GMED and SYK each lead in 1 of 2 comparable metrics.
Risk & Volatility
SYK is the less volatile stock with a 0.55 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GMED currently trades 83.9% from its 52-week high vs OFIX's 71.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.21x | 1.29x | 0.55x | 2.20x |
| 52-Week HighHighest price in past year | $16.99 | $101.40 | $404.87 | $20.06 |
| 52-Week LowLowest price in past year | $10.24 | $51.79 | $289.91 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +71.0% | +83.9% | +72.7% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 50.4 | 45.0 | 24.3 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 274K | 998K | 2.1M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: OFIX as "Hold", GMED as "Buy", SYK as "Buy", NVCR as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 30.1% for GMED (target: $111). SYK is the only dividend payer here at 1.14% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $18.00 | $110.67 | $403.69 | $33.50 |
| # AnalystsCovering analysts | 17 | 36 | 50 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — | +1.1% | — |
| Dividend StreakConsecutive years of raises | — | — | 34 | — |
| Dividend / ShareAnnual DPS | — | — | $3.36 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +2.6% | 0.0% | 0.0% |
GMED leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.
OFIX vs GMED vs SYK vs NVCR: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is OFIX or GMED or SYK or NVCR a better buy right now?
For growth investors, Globus Medical, Inc.
(GMED) is the stronger pick with 16. 7% revenue growth year-over-year, versus 2. 9% for Orthofix Medical Inc. (OFIX). Globus Medical, Inc. (GMED) offers the better valuation at 21. 7x trailing P/E (19. 0x forward), making it the more compelling value choice. Analysts rate Globus Medical, Inc. (GMED) a "Buy" — based on 36 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — OFIX or GMED or SYK or NVCR?
On trailing P/E, Globus Medical, Inc.
(GMED) is the cheapest at 21. 7x versus Stryker Corporation at 35. 0x. On forward P/E, Globus Medical, Inc. is actually cheaper at 19. 0x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Globus Medical, Inc. wins at 0. 61x versus Stryker Corporation's 1. 32x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — OFIX or GMED or SYK or NVCR?
Over the past 5 years, Stryker Corporation (SYK) delivered a total return of +21.
5%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: GMED returned +264. 4% versus OFIX's -72. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — OFIX or GMED or SYK or NVCR?
By beta (market sensitivity over 5 years), Stryker Corporation (SYK) is the lower-risk stock at 0.
55β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 303% more volatile than SYK relative to the S&P 500. On balance sheet safety, Globus Medical, Inc. (GMED) carries a lower debt/equity ratio of 3% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — OFIX or GMED or SYK or NVCR?
By revenue growth (latest reported year), Globus Medical, Inc.
(GMED) is pulling ahead at 16. 7% versus 2. 9% for Orthofix Medical Inc. (OFIX). On earnings-per-share growth, the picture is similar: Globus Medical, Inc. grew EPS 422. 7% year-over-year, compared to 8. 2% for Stryker Corporation. Over a 3-year CAGR, GMED leads at 42. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — OFIX or GMED or SYK or NVCR?
Globus Medical, Inc.
(GMED) is the more profitable company, earning 18. 3% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 18. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SYK leads at 19. 5% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is OFIX or GMED or SYK or NVCR more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Globus Medical, Inc. (GMED) is the more undervalued stock at a PEG of 0. 61x versus Stryker Corporation's 1. 32x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Globus Medical, Inc. (GMED) trades at 19. 0x forward P/E versus 19. 6x for Stryker Corporation — 0. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.
08Which pays a better dividend — OFIX or GMED or SYK or NVCR?
In this comparison, SYK (1.
1% yield) pays a dividend. OFIX, GMED, NVCR do not pay a meaningful dividend and should not be held primarily for income.
09Is OFIX or GMED or SYK or NVCR better for a retirement portfolio?
For long-horizon retirement investors, Stryker Corporation (SYK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
55), 1. 1% yield, +187. 1% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SYK: +187. 1%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between OFIX and GMED and SYK and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: OFIX is a small-cap quality compounder stock; GMED is a mid-cap high-growth stock; SYK is a mid-cap quality compounder stock; NVCR is a small-cap quality compounder stock. SYK pays a dividend while OFIX, GMED, NVCR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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