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Stock Comparison

OFIX vs XTNT vs NVCR vs ATEC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
OFIX
Orthofix Medical Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$488M
5Y Perf.-64.6%
XTNT
Xtant Medical Holdings, Inc.

Medical - Devices

HealthcareAMEX • US
Market Cap$80M
5Y Perf.-53.7%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-75.0%
ATEC
Alphatec Holdings, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.17B
5Y Perf.+74.2%

OFIX vs XTNT vs NVCR vs ATEC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
OFIX logoOFIX
XTNT logoXTNT
NVCR logoNVCR
ATEC logoATEC
IndustryMedical - DevicesMedical - DevicesMedical - Instruments & SuppliesMedical - Devices
Market Cap$488M$80M$1.92B$1.17B
Revenue (TTM)$825M$133M$674M$595M
Net Income (TTM)$-60M$2M$-173M$-125M
Gross Margin69.0%62.0%75.2%89.6%
Operating Margin-4.0%4.8%-27.2%-9.6%
Forward P/E27.1x
Total Debt$229M$35M$290M$620M
Cash & Equiv.$82M$6M$103M$161M

OFIX vs XTNT vs NVCR vs ATECLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

OFIX
XTNT
NVCR
ATEC
StockMay 20May 26Return
Orthofix Medical In… (OFIX)10035.4-64.6%
Xtant Medical Holdi… (XTNT)10046.3-53.7%
NovoCure Limited (NVCR)10025.0-75.0%
Alphatec Holdings, … (ATEC)100174.2+74.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: OFIX vs XTNT vs NVCR vs ATEC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: XTNT leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
OFIX
Orthofix Medical Inc.
The Specific-Use Pick

In this particular matchup, OFIX is outpaced on most metrics by others in the set.

Best for: healthcare exposure
XTNT
Xtant Medical Holdings, Inc.
The Income Pick

XTNT carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.69
  • Rev growth 28.4%, EPS growth 107.7%, 3Y rev CAGR 28.5%
  • Lower volatility, beta 0.69, Low D/E 81.8%, current ratio 2.35x
  • Beta 0.69, current ratio 2.35x
Best for: income & stability and growth exposure
NVCR
NovoCure Limited
The Specific-Use Pick

NVCR plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
ATEC
Alphatec Holdings, Inc.
The Long-Run Compounder

ATEC is the clearest fit if your priority is long-term compounding.

  • 225.4% 10Y total return vs NVCR's 30.3%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthXTNT logoXTNT28.4% revenue growth vs OFIX's 2.9%
Quality / MarginsXTNT logoXTNT1.3% margin vs NVCR's -25.7%
Stability / SafetyXTNT logoXTNTBeta 0.69 vs NVCR's 2.20, lower leverage
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)XTNT logoXTNT+10.0% vs ATEC's -37.8%
Efficiency (ROA)XTNT logoXTNT1.8% ROA vs NVCR's -16.5%, ROIC -12.8% vs -16.4%

OFIX vs XTNT vs NVCR vs ATEC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

OFIXOrthofix Medical Inc.
FY 2025
Global Spine
100.0%$688M
XTNTXtant Medical Holdings, Inc.
FY 2024
Orthobiologics
56.6%$66M
Spinal Implant
42.1%$49M
License Revenue
1.3%$2M
NVCRNovoCure Limited

Segment breakdown not available.

ATECAlphatec Holdings, Inc.
FY 2025
Products And Services
100.0%$764M

OFIX vs XTNT vs NVCR vs ATEC — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLXTNTLAGGINGATEC

Income & Cash Flow (Last 12 Months)

XTNT leads this category, winning 5 of 6 comparable metrics.

OFIX is the larger business by revenue, generating $825M annually — 6.2x XTNT's $133M. XTNT is the more profitable business, keeping 1.3% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, XTNT holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
RevenueTrailing 12 months$825M$133M$674M$595M
EBITDAEarnings before interest/tax$102M$11M-$165M$4M
Net IncomeAfter-tax profit-$60M$2M-$173M-$125M
Free Cash FlowCash after capex-$4M$5M-$48M$7M
Gross MarginGross profit ÷ Revenue+69.0%+62.0%+75.2%+89.6%
Operating MarginEBIT ÷ Revenue-4.0%+4.8%-27.2%-9.6%
Net MarginNet income ÷ Revenue-7.3%+1.3%-25.7%-21.1%
FCF MarginFCF ÷ Revenue-0.4%+3.9%-7.1%+1.2%
Rev. Growth (YoY)Latest quarter vs prior year+1.6%+19.0%+12.3%-100.0%
EPS Growth (YoY)Latest quarter vs prior year+61.5%+123.7%-100.0%+37.1%
XTNT leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

OFIX leads this category, winning 2 of 3 comparable metrics.
MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
Market CapShares × price$488M$80M$1.9B$1.2B
Enterprise ValueMkt cap + debt − cash$635M$109M$2.1B$1.6B
Trailing P/EPrice ÷ TTM EPS-5.29x-4.75x-13.80x-8.07x
Forward P/EPrice ÷ next-FY EPS est.27.09x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple3752.09x
Price / SalesMarket cap ÷ Revenue0.59x0.68x2.92x1.54x
Price / BookPrice ÷ Book value/share1.07x1.77x5.51x32.28x
Price / FCFMarket cap ÷ FCF422.56x
OFIX leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

XTNT leads this category, winning 5 of 9 comparable metrics.

XTNT delivers a 3.8% return on equity — every $100 of shareholder capital generates $4 in annual profit, vs $-4 for ATEC. OFIX carries lower financial leverage with a 0.51x debt-to-equity ratio, signaling a more conservative balance sheet compared to ATEC's 17.21x. On the Piotroski fundamental quality scale (0–9), ATEC scores 6/9 vs XTNT's 2/9, reflecting solid financial health.

MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
ROE (TTM)Return on equity-13.4%+3.8%-50.8%-4.4%
ROA (TTM)Return on assets-7.0%+1.8%-16.5%-15.8%
ROICReturn on invested capital-8.6%-12.8%-16.4%-12.6%
ROCEReturn on capital employed-9.7%-17.9%-28.9%-13.7%
Piotroski ScoreFundamental quality 0–94256
Debt / EquityFinancial leverage0.51x0.82x0.85x17.21x
Net DebtTotal debt minus cash$147M$29M$187M$459M
Cash & Equiv.Liquid assets$82M$6M$103M$161M
Total DebtShort + long-term debt$229M$35M$290M$620M
Interest CoverageEBIT ÷ Interest expense-4.97x1.55x-96.80x-3.29x
XTNT leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

XTNT leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ATEC five years ago would be worth $5,129 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, XTNT leads with a +10.0% total return vs ATEC's -37.8%. The 3-year compound annual growth rate (CAGR) favors XTNT at -4.3% vs NVCR's -37.6% — a key indicator of consistent wealth creation.

MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
YTD ReturnYear-to-date-18.7%-24.0%+28.3%-62.7%
1-Year ReturnPast 12 months+0.4%+10.0%+1.1%-37.8%
3-Year ReturnCumulative with dividends-35.1%-12.3%-75.7%-47.8%
5-Year ReturnCumulative with dividends-72.7%-66.1%-91.3%-48.7%
10-Year ReturnCumulative with dividends-72.0%-97.8%+30.3%+225.4%
CAGR (3Y)Annualised 3-year return-13.4%-4.3%-37.6%-19.5%
XTNT leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — XTNT and NVCR each lead in 1 of 2 comparable metrics.

XTNT is the less volatile stock with a 0.69 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NVCR currently trades 83.9% from its 52-week high vs ATEC's 33.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
Beta (5Y)Sensitivity to S&P 5001.21x0.69x2.20x1.13x
52-Week HighHighest price in past year$16.99$0.95$20.06$23.29
52-Week LowLowest price in past year$10.24$0.44$9.82$6.85
% of 52W HighCurrent price vs 52-week peak+71.0%+60.0%+83.9%+33.3%
RSI (14)Momentum oscillator 0–10050.460.969.826.8
Avg Volume (50D)Average daily shares traded274K142K1.5M3.0M
Evenly matched — XTNT and NVCR each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: OFIX as "Hold", NVCR as "Buy", ATEC as "Buy". Consensus price targets imply 222.6% upside for ATEC (target: $25) vs 49.1% for OFIX (target: $18).

MetricOFIX logoOFIXOrthofix Medical …XTNT logoXTNTXtant Medical Hol…NVCR logoNVCRNovoCure LimitedATEC logoATECAlphatec Holdings…
Analyst RatingConsensus buy/hold/sellHoldBuyBuy
Price TargetConsensus 12-month target$18.00$33.50$25.00
# AnalystsCovering analysts171516
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

XTNT leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). OFIX leads in 1 (Valuation Metrics). 1 tied.

Best OverallXtant Medical Holdings, Inc. (XTNT)Leads 3 of 6 categories
Loading custom metrics...

OFIX vs XTNT vs NVCR vs ATEC: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is OFIX or XTNT or NVCR or ATEC a better buy right now?

For growth investors, Xtant Medical Holdings, Inc.

(XTNT) is the stronger pick with 28. 4% revenue growth year-over-year, versus 2. 9% for Orthofix Medical Inc. (OFIX). Analysts rate NovoCure Limited (NVCR) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — OFIX or XTNT or NVCR or ATEC?

Over the past 5 years, Alphatec Holdings, Inc.

(ATEC) delivered a total return of -48. 7%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: ATEC returned +225. 4% versus XTNT's -97. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — OFIX or XTNT or NVCR or ATEC?

By beta (market sensitivity over 5 years), Xtant Medical Holdings, Inc.

(XTNT) is the lower-risk stock at 0. 69β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 220% more volatile than XTNT relative to the S&P 500. On balance sheet safety, Orthofix Medical Inc. (OFIX) carries a lower debt/equity ratio of 51% versus 17% for Alphatec Holdings, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — OFIX or XTNT or NVCR or ATEC?

By revenue growth (latest reported year), Xtant Medical Holdings, Inc.

(XTNT) is pulling ahead at 28. 4% versus 2. 9% for Orthofix Medical Inc. (OFIX). On earnings-per-share growth, the picture is similar: Orthofix Medical Inc. grew EPS 30. 9% year-over-year, compared to 15. 0% for Alphatec Holdings, Inc.. Over a 3-year CAGR, ATEC leads at 29. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — OFIX or XTNT or NVCR or ATEC?

Orthofix Medical Inc.

(OFIX) is the more profitable company, earning -11. 2% net margin versus -20. 8% for NovoCure Limited — meaning it keeps -11. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: OFIX leads at -8. 3% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is OFIX or XTNT or NVCR or ATEC more undervalued right now?

Analyst consensus price targets imply the most upside for ATEC: 222.

6% to $25. 00.

07

Which pays a better dividend — OFIX or XTNT or NVCR or ATEC?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is OFIX or XTNT or NVCR or ATEC better for a retirement portfolio?

For long-horizon retirement investors, Xtant Medical Holdings, Inc.

(XTNT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 69)). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (XTNT: -97. 8%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between OFIX and XTNT and NVCR and ATEC?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: OFIX is a small-cap quality compounder stock; XTNT is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; ATEC is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

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OFIX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 41%
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XTNT

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
  • Gross Margin > 37%
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NVCR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 45%
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ATEC

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 53%
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Beat Both

Find stocks that outperform OFIX and XTNT and NVCR and ATEC on the metrics below

Revenue Growth>
%
(OFIX: 1.6% · XTNT: 19.0%)

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