Biotechnology
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OLMA vs DBVT vs AZN vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - General
Medical - Diagnostics & Research
OLMA vs DBVT vs AZN vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - General | Medical - Diagnostics & Research |
| Market Cap | $1.23B | $1712.35T | $282.96B | $30.32B |
| Revenue (TTM) | $0.00 | $0.00 | $60.44B | $16.63B |
| Net Income (TTM) | $-162M | $-168M | $10.39B | $1.39B |
| Gross Margin | — | — | 81.7% | 26.1% |
| Operating Margin | — | — | 23.7% | 13.9% |
| Forward P/E | — | — | 17.7x | 14.1x |
| Total Debt | $1M | $22M | $29.70B | $16.17B |
| Cash & Equiv. | $48M | $194M | $5.71B | $1.98B |
OLMA vs DBVT vs AZN vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 20 | May 26 | Return |
|---|---|---|---|
| Olema Pharmaceutica… (OLMA) | 100 | 29.7 | -70.3% |
| DBV Technologies S.… (DBVT) | 100 | 81.6 | -18.4% |
| AstraZeneca PLC (AZN) | 100 | 175.3 | +75.3% |
| IQVIA Holdings Inc. (IQV) | 100 | 105.7 | +5.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OLMA vs DBVT vs AZN vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
OLMA is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 1.18, Low D/E 0.2%, current ratio 9.95x
- Beta 1.18, current ratio 9.95x
- +226.8% vs IQV's +16.5%
DBVT lags the leaders in this set but could rank higher in a more targeted comparison.
AZN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 4 yrs, beta 0.67, yield 1.8%
- Rev growth 8.6%, EPS growth 190.7%, 3Y rev CAGR 9.8%
- 268.6% 10Y total return vs IQV's 166.5%
- 8.6% revenue growth vs DBVT's -100.0%
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.35 vs AZN's 0.81
- Lower P/E (14.1x vs 17.7x), PEG 0.35 vs 0.81
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (14.1x vs 17.7x), PEG 0.35 vs 0.81 | |
| Quality / Margins | 17.2% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.67 vs IQV's 1.33, lower leverage | |
| Dividends | 1.8% yield; 4-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +226.8% vs IQV's +16.5% | |
| Efficiency (ROA) | 9.1% ROA vs DBVT's -89.0% |
OLMA vs DBVT vs AZN vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
OLMA vs DBVT vs AZN vs IQV — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
AZN leads in 4 of 6 categories
IQV leads 1 • OLMA leads 1 • DBVT leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
AZN leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
AZN and DBVT operate at a comparable scale, with $60.4B and $0 in trailing revenue. AZN is the more profitable business, keeping 17.2% of every revenue dollar as net income compared to IQV's 8.3%. On growth, AZN holds the edge at +12.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $60.4B | $16.6B |
| EBITDAEarnings before interest/tax | -$178M | -$112M | $20.1B | $3.5B |
| Net IncomeAfter-tax profit | -$162M | -$168M | $10.4B | $1.4B |
| Free Cash FlowCash after capex | -$147M | -$151M | $9.1B | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | — | +81.7% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | — | +23.7% | +13.9% |
| Net MarginNet income ÷ Revenue | — | — | +17.2% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | — | +15.1% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +12.5% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +10.5% | +91.5% | +5.3% | +15.0% |
Valuation Metrics
IQV leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 22.8x trailing earnings, IQV trades at a 18% valuation discount to AZN's 27.9x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs AZN's 1.28x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.2B | $1712.35T | $283.0B | $30.3B |
| Enterprise ValueMkt cap + debt − cash | $1.2B | $1712.35T | $306.9B | $44.5B |
| Trailing P/EPrice ÷ TTM EPS | -8.09x | -0.76x | 27.91x | 22.79x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 17.74x | 14.06x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.28x | 0.56x |
| EV / EBITDAEnterprise value multiple | — | — | 15.76x | 12.97x |
| Price / SalesMarket cap ÷ Revenue | — | — | 4.82x | 1.86x |
| Price / BookPrice ÷ Book value/share | 2.75x | 0.66x | 5.85x | 4.67x |
| Price / FCFMarket cap ÷ FCF | — | — | 24.05x | 14.78x |
Profitability & Efficiency
AZN leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
AZN delivers a 22.2% return on equity — every $100 of shareholder capital generates $22 in annual profit, vs $-130 for DBVT. OLMA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), AZN scores 8/9 vs OLMA's 3/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -42.9% | -130.2% | +22.2% | +22.1% |
| ROA (TTM)Return on assets | -38.7% | -89.0% | +9.1% | +4.7% |
| ROICReturn on invested capital | -38.2% | — | +14.9% | +8.7% |
| ROCEReturn on capital employed | -40.1% | -145.7% | +17.2% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 8 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.13x | 0.61x | 2.44x |
| Net DebtTotal debt minus cash | -$47M | -$172M | $24.0B | $14.2B |
| Cash & Equiv.Liquid assets | $48M | $194M | $5.7B | $2.0B |
| Total DebtShort + long-term debt | $1M | $22M | $29.7B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | 8.43x | 3.10x |
Total Returns (Dividends Reinvested)
OLMA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in AZN five years ago would be worth $18,221 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, OLMA leads with a +226.8% total return vs IQV's +16.5%. The 3-year compound annual growth rate (CAGR) favors OLMA at 32.1% vs IQV's -2.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -40.2% | +4.9% | +1.1% | -20.7% |
| 1-Year ReturnPast 12 months | +226.8% | +110.4% | +33.9% | +16.5% |
| 3-Year ReturnCumulative with dividends | +130.3% | +19.7% | +30.4% | -5.9% |
| 5-Year ReturnCumulative with dividends | -30.0% | -69.1% | +82.2% | -23.8% |
| 10-Year ReturnCumulative with dividends | -69.1% | -87.0% | +268.6% | +166.5% |
| CAGR (3Y)Annualised 3-year return | +32.1% | +6.2% | +9.3% | -2.0% |
Risk & Volatility
AZN leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
AZN is the less volatile stock with a 0.67 beta — it tends to amplify market swings less than IQV's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. AZN currently trades 85.8% from its 52-week high vs OLMA's 41.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.18x | 1.26x | 0.67x | 1.33x |
| 52-Week HighHighest price in past year | $36.13 | $26.18 | $212.71 | $247.05 |
| 52-Week LowLowest price in past year | $3.89 | $7.53 | $91.44 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +41.9% | +76.3% | +85.8% | +72.3% |
| RSI (14)Momentum oscillator 0–100 | 45.7 | 48.1 | 39.1 | 58.5 |
| Avg Volume (50D)Average daily shares traded | 1.4M | 252K | 1.9M | 1.6M |
Analyst Outlook
AZN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: OLMA as "Buy", DBVT as "Buy", AZN as "Buy", IQV as "Buy". Consensus price targets imply 180.9% upside for OLMA (target: $43) vs 15.6% for AZN (target: $211). AZN is the only dividend payer here at 1.78% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $42.50 | $46.33 | $211.00 | $225.63 |
| # AnalystsCovering analysts | 8 | 15 | 41 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | — | +1.8% | — |
| Dividend StreakConsecutive years of raises | — | 0 | 4 | 2 |
| Dividend / ShareAnnual DPS | — | — | $3.25 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.3% | +4.1% |
AZN leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IQV leads in 1 (Valuation Metrics).
OLMA vs DBVT vs AZN vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is OLMA or DBVT or AZN or IQV a better buy right now?
For growth investors, AstraZeneca PLC (AZN) is the stronger pick with 8.
6% revenue growth year-over-year, versus 5. 9% for IQVIA Holdings Inc. (IQV). IQVIA Holdings Inc. (IQV) offers the better valuation at 22. 8x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Olema Pharmaceuticals, Inc. (OLMA) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — OLMA or DBVT or AZN or IQV?
On trailing P/E, IQVIA Holdings Inc.
(IQV) is the cheapest at 22. 8x versus AstraZeneca PLC at 27. 9x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus AstraZeneca PLC's 0. 81x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — OLMA or DBVT or AZN or IQV?
Over the past 5 years, AstraZeneca PLC (AZN) delivered a total return of +82.
2%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: AZN returned +268. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — OLMA or DBVT or AZN or IQV?
By beta (market sensitivity over 5 years), AstraZeneca PLC (AZN) is the lower-risk stock at 0.
67β versus IQVIA Holdings Inc. 's 1. 33β — meaning IQV is approximately 99% more volatile than AZN relative to the S&P 500. On balance sheet safety, Olema Pharmaceuticals, Inc. (OLMA) carries a lower debt/equity ratio of 0% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — OLMA or DBVT or AZN or IQV?
By revenue growth (latest reported year), AstraZeneca PLC (AZN) is pulling ahead at 8.
6% versus 5. 9% for IQVIA Holdings Inc. (IQV). On earnings-per-share growth, the picture is similar: AstraZeneca PLC grew EPS 190. 7% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, AZN leads at 9. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — OLMA or DBVT or AZN or IQV?
AstraZeneca PLC (AZN) is the more profitable company, earning 17.
5% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 17. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: AZN leads at 23. 4% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — AZN leads at 81. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is OLMA or DBVT or AZN or IQV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus AstraZeneca PLC's 0. 81x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 14. 1x forward P/E versus 17. 7x for AstraZeneca PLC — 3. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for OLMA: 180. 9% to $42. 50.
08Which pays a better dividend — OLMA or DBVT or AZN or IQV?
In this comparison, AZN (1.
8% yield) pays a dividend. OLMA, DBVT, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is OLMA or DBVT or AZN or IQV better for a retirement portfolio?
For long-horizon retirement investors, AstraZeneca PLC (AZN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
67), 1. 8% yield, +268. 6% 10Y return). Both have compounded well over 10 years (AZN: +268. 6%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between OLMA and DBVT and AZN and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
AZN pays a dividend while OLMA, DBVT, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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