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PLUR vs NTLA vs EDIT vs FATE
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
PLUR vs NTLA vs EDIT vs FATE — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $27M | $1.62B | $297M | $280M |
| Revenue (TTM) | $1M | $68M | $0.00 | $7M |
| Net Income (TTM) | $-26M | $-413M | $-160M | $-136M |
| Gross Margin | 21.3% | -25.6% | — | — |
| Operating Margin | -18.6% | -6.5% | — | -22.2% |
| Total Debt | $34M | $93M | $18M | $78M |
| Cash & Equiv. | $6M | $155M | $147M | $47M |
PLUR vs NTLA vs EDIT vs FATE — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Pluri Inc. (PLUR) | 100 | 5.2 | -94.8% |
| Intellia Therapeuti… (NTLA) | 100 | 78.3 | -21.7% |
| Editas Medicine, In… (EDIT) | 100 | 11.2 | -88.8% |
| Fate Therapeutics, … (FATE) | 100 | 7.5 | -92.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: PLUR vs NTLA vs EDIT vs FATE
Each card shows where this stock fits in a portfolio — not just who wins on paper.
PLUR carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.06
- Rev growth 309.8%, EPS growth 10.8%, 3Y rev CAGR 78.7%
- 309.8% revenue growth vs EDIT's -100.0%
- Beta 1.06 vs EDIT's 2.52
NTLA is the clearest fit if your priority is long-term compounding.
- -42.9% 10Y total return vs FATE's 40.5%
- -6.1% margin vs FATE's -20.5%
EDIT lags the leaders in this set but could rank higher in a more targeted comparison.
FATE is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 2.17, Low D/E 37.6%, current ratio 5.79x
- Beta 2.17, current ratio 5.79x
- +143.0% vs PLUR's -32.5%
- -42.7% ROA vs PLUR's -74.5%, ROIC -36.5% vs -59.9%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 309.8% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | -6.1% margin vs FATE's -20.5% | |
| Stability / Safety | Beta 1.06 vs EDIT's 2.52 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +143.0% vs PLUR's -32.5% | |
| Efficiency (ROA) | -42.7% ROA vs PLUR's -74.5%, ROIC -36.5% vs -59.9% |
PLUR vs NTLA vs EDIT vs FATE — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
PLUR vs NTLA vs EDIT vs FATE — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NTLA leads in 1 of 6 categories
FATE leads 1 • PLUR leads 0 • EDIT leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NTLA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NTLA and EDIT operate at a comparable scale, with $68M and $0 in trailing revenue. NTLA is the more profitable business, keeping -6.1% of every revenue dollar as net income compared to FATE's -20.5%. On growth, NTLA holds the edge at +78.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1M | $68M | $0 | $7M |
| EBITDAEarnings before interest/tax | -$24M | -$431M | $0 | -$148M |
| Net IncomeAfter-tax profit | -$26M | -$413M | -$160M | -$136M |
| Free Cash FlowCash after capex | -$22M | -$396M | -$166M | -$88M |
| Gross MarginGross profit ÷ Revenue | +21.3% | -25.6% | — | — |
| Operating MarginEBIT ÷ Revenue | -18.6% | -6.5% | — | -22.2% |
| Net MarginNet income ÷ Revenue | -19.5% | -6.1% | — | -20.5% |
| FCF MarginFCF ÷ Revenue | -16.4% | -5.8% | — | -13.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +7.0% | +78.8% | -151.6% | -26.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -34.0% | +34.6% | +105.5% | +38.6% |
Valuation Metrics
Evenly matched — PLUR and NTLA and FATE each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $27M | $1.6B | $297M | $280M |
| Enterprise ValueMkt cap + debt − cash | $55M | $1.6B | $168M | $312M |
| Trailing P/EPrice ÷ TTM EPS | -0.94x | -3.60x | -1.68x | -2.11x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 20.41x | 23.93x | — | 42.18x |
| Price / BookPrice ÷ Book value/share | — | 2.21x | 9.85x | 1.39x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — NTLA and FATE each lead in 3 of 8 comparable metrics.
Profitability & Efficiency
NTLA delivers a -56.6% return on equity — every $100 of shareholder capital generates $-57 in annual profit, vs $-10 for PLUR. NTLA carries lower financial leverage with a 0.14x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), NTLA scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -9.9% | -56.6% | -5.2% | -65.8% |
| ROA (TTM)Return on assets | -74.5% | -45.2% | -74.2% | -42.7% |
| ROICReturn on invested capital | -59.9% | -44.0% | — | -36.5% |
| ROCEReturn on capital employed | -107.1% | -48.5% | — | -43.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 4 | 1 | 2 |
| Debt / EquityFinancial leverage | — | 0.14x | 0.66x | 0.38x |
| Net DebtTotal debt minus cash | $28M | -$62M | -$129M | $31M |
| Cash & Equiv.Liquid assets | $6M | $155M | $147M | $47M |
| Total DebtShort + long-term debt | $34M | $93M | $18M | $78M |
| Interest CoverageEBIT ÷ Interest expense | -29.30x | — | — | — |
Total Returns (Dividends Reinvested)
FATE leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NTLA five years ago would be worth $2,024 today (with dividends reinvested), compared to $318 for FATE. Over the past 12 months, FATE leads with a +143.0% total return vs PLUR's -32.5%. The 3-year compound annual growth rate (CAGR) favors PLUR at -23.2% vs EDIT's -32.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +11.7% | +48.9% | +47.8% | +145.5% |
| 1-Year ReturnPast 12 months | -32.5% | +88.1% | +127.8% | +143.0% |
| 3-Year ReturnCumulative with dividends | -54.6% | -68.3% | -68.5% | -55.4% |
| 5-Year ReturnCumulative with dividends | -89.4% | -79.8% | -91.1% | -96.8% |
| 10-Year ReturnCumulative with dividends | -97.3% | -42.9% | -90.0% | +40.5% |
| CAGR (3Y)Annualised 3-year return | -23.2% | -31.8% | -32.0% | -23.6% |
Risk & Volatility
Evenly matched — PLUR and FATE each lead in 1 of 2 comparable metrics.
Risk & Volatility
PLUR is the less volatile stock with a 1.06 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 98.6% from its 52-week high vs NTLA's 48.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.06x | 2.37x | 2.52x | 2.17x |
| 52-Week HighHighest price in past year | $6.10 | $28.25 | $4.54 | $2.46 |
| 52-Week LowLowest price in past year | $2.82 | $6.83 | $1.29 | $0.91 |
| % of 52W HighCurrent price vs 52-week peak | +54.8% | +48.5% | +66.7% | +98.6% |
| RSI (14)Momentum oscillator 0–100 | 46.4 | 50.4 | 57.5 | 81.0 |
| Avg Volume (50D)Average daily shares traded | 6K | 5.3M | 1.6M | 1.9M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: NTLA as "Buy", EDIT as "Buy", FATE as "Buy". Consensus price targets imply 1525.5% upside for FATE (target: $40) vs 52.3% for NTLA (target: $21).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $12.00 | $20.88 | $6.00 | $39.50 |
| # AnalystsCovering analysts | — | 39 | 25 | 31 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
NTLA leads in 1 of 6 categories (Income & Cash Flow). FATE leads in 1 (Total Returns). 3 tied.
PLUR vs NTLA vs EDIT vs FATE: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is PLUR or NTLA or EDIT or FATE a better buy right now?
For growth investors, Pluri Inc.
(PLUR) is the stronger pick with 309. 8% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Intellia Therapeutics, Inc. (NTLA) a "Buy" — based on 39 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — PLUR or NTLA or EDIT or FATE?
Over the past 5 years, Intellia Therapeutics, Inc.
(NTLA) delivered a total return of -79. 8%, compared to -96. 8% for Fate Therapeutics, Inc. (FATE). Over 10 years, the gap is even starker: FATE returned +40. 5% versus PLUR's -97. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — PLUR or NTLA or EDIT or FATE?
By beta (market sensitivity over 5 years), Pluri Inc.
(PLUR) is the lower-risk stock at 1. 06β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 138% more volatile than PLUR relative to the S&P 500. On balance sheet safety, Intellia Therapeutics, Inc. (NTLA) carries a lower debt/equity ratio of 14% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — PLUR or NTLA or EDIT or FATE?
By revenue growth (latest reported year), Pluri Inc.
(PLUR) is pulling ahead at 309. 8% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to 10. 8% for Pluri Inc.. Over a 3-year CAGR, PLUR leads at 78. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — PLUR or NTLA or EDIT or FATE?
Editas Medicine, Inc.
(EDIT) is the more profitable company, earning 0. 0% net margin versus -20. 5% for Fate Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -22. 2% for FATE. At the gross margin level — before operating expenses — NTLA leads at 76. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — PLUR or NTLA or EDIT or FATE?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is PLUR or NTLA or EDIT or FATE better for a retirement portfolio?
For long-horizon retirement investors, Pluri Inc.
(PLUR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 06)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PLUR: -97. 3%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between PLUR and NTLA and EDIT and FATE?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: PLUR is a small-cap high-growth stock; NTLA is a small-cap high-growth stock; EDIT is a small-cap quality compounder stock; FATE is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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