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Stock Comparison

PRFX vs PCRX vs PRGO vs BHC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PRFX
PainReform Ltd.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • IL
Market Cap$862K
5Y Perf.-99.9%
PCRX
Pacira BioSciences, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$930M
5Y Perf.-61.5%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.61B
5Y Perf.-74.5%
BHC
Bausch Health Companies Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • CA
Market Cap$2.14B
5Y Perf.-63.0%

PRFX vs PCRX vs PRGO vs BHC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PRFX logoPRFX
PCRX logoPCRX
PRGO logoPRGO
BHC logoBHC
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic
Market Cap$862K$930M$1.61B$2.14B
Revenue (TTM)$0.00$735M$4.18B$10.55B
Net Income (TTM)$-4M$9M$-1.82B$-1.19B
Gross Margin60.2%34.2%61.7%
Operating Margin3.4%-4.1%22.9%
Forward P/E8.1x5.5x1.3x
Total Debt$45K$454M$3.97B$21.21B
Cash & Equiv.$4M$159M$532M$1.32B

PRFX vs PCRX vs PRGO vs BHCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PRFX
PCRX
PRGO
BHC
StockSep 20May 26Return
PainReform Ltd. (PRFX)1000.1-99.9%
Pacira BioSciences,… (PCRX)10038.5-61.5%
Perrigo Company plc (PRGO)10025.5-74.5%
Bausch Health Compa… (BHC)10037.0-63.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: PRFX vs PCRX vs PRGO vs BHC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PRFX and PCRX are tied at the top with 2 categories each — the right choice depends on your priorities. Pacira BioSciences, Inc. is the stronger pick specifically for capital preservation and lower volatility and operational efficiency and capital deployment. BHC and PRGO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
PRFX
PainReform Ltd.
The Growth Leader

PRFX has the current edge in this matchup, primarily because of its strength in growth and quality.

  • 77.9% revenue growth vs PRGO's -2.8%
  • 1.9% margin vs PRGO's -43.5%
Best for: growth and quality
PCRX
Pacira BioSciences, Inc.
The Long-Run Compounder

PCRX is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.

  • -51.2% 10Y total return vs PRGO's -77.7%
  • Lower volatility, beta 0.47, Low D/E 65.6%, current ratio 4.54x
  • Beta 0.47, current ratio 4.54x
  • Beta 0.47 vs PRFX's 1.73
Best for: long-term compounding and sleep-well-at-night
PRGO
Perrigo Company plc
The Income Pick

PRGO is the clearest fit if your priority is income & stability.

  • Dividend streak 10 yrs, beta 1.18, yield 9.8%
  • 9.8% yield; 10-year raise streak; the other 3 pay no meaningful dividend
Best for: income & stability
BHC
Bausch Health Companies Inc.
The Growth Play

BHC is the clearest fit if your priority is growth exposure.

  • Rev growth 8.5%, EPS growth 430.8%, 3Y rev CAGR 8.7%
  • Lower P/E (1.3x vs 5.5x)
  • +21.8% vs PRFX's -82.1%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthPRFX logoPRFX77.9% revenue growth vs PRGO's -2.8%
ValueBHC logoBHCLower P/E (1.3x vs 5.5x)
Quality / MarginsPRFX logoPRFX1.9% margin vs PRGO's -43.5%
Stability / SafetyPCRX logoPCRXBeta 0.47 vs PRFX's 1.73
DividendsPRGO logoPRGO9.8% yield; 10-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)BHC logoBHC+21.8% vs PRFX's -82.1%
Efficiency (ROA)PCRX logoPCRX0.7% ROA vs PRFX's -36.6%

PRFX vs PCRX vs PRGO vs BHC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

PRFXPainReform Ltd.

Segment breakdown not available.

PCRXPacira BioSciences, Inc.
FY 2025
Product
50.9%$723M
EXPAREL
40.5%$575M
ZILRETTA
8.2%$117M
Bupivacaine Liposome Injectable Suspension
0.5%$7M
PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
BHCBausch Health Companies Inc.
FY 2025
Product
49.5%$10.2B
Pharmaceutical Products
23.1%$4.7B
Device Products
11.9%$2.4B
Over the Counter Products
9.8%$2.0B
Branded and Other Generic Products
4.7%$962M
Other Revenues
0.5%$110M
Product and Service, Other
0.5%$110M

PRFX vs PCRX vs PRGO vs BHC — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBHCLAGGINGPRFX

Income & Cash Flow (Last 12 Months)

BHC leads this category, winning 3 of 6 comparable metrics.

BHC and PRFX operate at a comparable scale, with $10.6B and $0 in trailing revenue. PCRX is the more profitable business, keeping 1.3% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, BHC holds the edge at +10.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
RevenueTrailing 12 months$0$735M$4.2B$10.6B
EBITDAEarnings before interest/tax-$4M$95M$58M$3.6B
Net IncomeAfter-tax profit-$4M$9M-$1.8B-$1.2B
Free Cash FlowCash after capex-$6M$133M$108M$990M
Gross MarginGross profit ÷ Revenue+60.2%+34.2%+61.7%
Operating MarginEBIT ÷ Revenue+3.4%-4.1%+22.9%
Net MarginNet income ÷ Revenue+1.3%-43.5%-11.3%
FCF MarginFCF ÷ Revenue+18.1%+2.6%+9.4%
Rev. Growth (YoY)Latest quarter vs prior year+5.0%-7.2%+10.5%
EPS Growth (YoY)Latest quarter vs prior year+98.9%-30.0%-56.4%-22.7%
BHC leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

BHC leads this category, winning 4 of 6 comparable metrics.

At 13.3x trailing earnings, BHC trades at a 91% valuation discount to PCRX's 147.8x P/E. On an enterprise value basis, BHC's 6.4x EV/EBITDA is more attractive than PCRX's 9.9x.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
Market CapShares × price$861,734$930M$1.6B$2.1B
Enterprise ValueMkt cap + debt − cash-$3M$1.2B$5.1B$22.0B
Trailing P/EPrice ÷ TTM EPS-0.06x147.75x-1.14x13.31x
Forward P/EPrice ÷ next-FY EPS est.8.13x5.53x1.33x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple9.86x7.42x6.38x
Price / SalesMarket cap ÷ Revenue1.28x0.38x0.20x
Price / BookPrice ÷ Book value/share0.47x1.54x0.55x5.71x
Price / FCFMarket cap ÷ FCF6.80x11.12x2.13x
BHC leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

Evenly matched — PRFX and PCRX and BHC each lead in 3 of 9 comparable metrics.

BHC delivers a 5.9% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-51 for PRGO. PRFX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to BHC's 56.36x. On the Piotroski fundamental quality scale (0–9), PCRX scores 9/9 vs PRFX's 1/9, reflecting strong financial health.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
ROE (TTM)Return on equity-48.4%+1.3%-50.7%+5.9%
ROA (TTM)Return on assets-36.6%+0.7%-19.8%-4.5%
ROICReturn on invested capital+2.3%+3.7%+8.2%
ROCEReturn on capital employed-3.1%+2.8%+4.3%+10.6%
Piotroski ScoreFundamental quality 0–91947
Debt / EquityFinancial leverage0.02x0.66x1.35x56.36x
Net DebtTotal debt minus cash-$4M$296M$3.4B$19.9B
Cash & Equiv.Liquid assets$4M$159M$532M$1.3B
Total DebtShort + long-term debt$45,000$454M$4.0B$21.2B
Interest CoverageEBIT ÷ Interest expense-1048.07x2.37x-7.20x1.43x
Evenly matched — PRFX and PCRX and BHC each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

BHC leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in PRGO five years ago would be worth $3,986 today (with dividends reinvested), compared to $23 for PRFX. Over the past 12 months, BHC leads with a +21.8% total return vs PRFX's -82.1%. The 3-year compound annual growth rate (CAGR) favors BHC at -1.5% vs PRFX's -78.7% — a key indicator of consistent wealth creation.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
YTD ReturnYear-to-date-45.6%-3.4%-13.5%-20.6%
1-Year ReturnPast 12 months-82.1%-6.1%-51.2%+21.8%
3-Year ReturnCumulative with dividends-99.0%-44.1%-58.1%-4.4%
5-Year ReturnCumulative with dividends-99.8%-62.6%-60.1%-79.6%
10-Year ReturnCumulative with dividends-99.9%-51.2%-77.7%-79.6%
CAGR (3Y)Annualised 3-year return-78.7%-17.6%-25.2%-1.5%
BHC leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

PCRX leads this category, winning 2 of 2 comparable metrics.

PCRX is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than PRFX's 1.73 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PCRX currently trades 85.5% from its 52-week high vs PRFX's 10.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
Beta (5Y)Sensitivity to S&P 5001.69x0.41x1.21x0.96x
52-Week HighHighest price in past year$17.95$27.64$28.44$8.69
52-Week LowLowest price in past year$0.77$18.80$9.23$4.41
% of 52W HighCurrent price vs 52-week peak+10.6%+85.5%+41.2%+65.9%
RSI (14)Momentum oscillator 0–10035.045.960.952.3
Avg Volume (50D)Average daily shares traded622K695K3.4M1.8M
PCRX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

PRGO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: PCRX as "Hold", PRGO as "Hold", BHC as "Buy". Consensus price targets imply 208.9% upside for PRGO (target: $36) vs 24.8% for PCRX (target: $30). PRGO is the only dividend payer here at 9.81% yield — a key consideration for income-focused portfolios.

MetricPRFX logoPRFXPainReform Ltd.PCRX logoPCRXPacira BioScience…PRGO logoPRGOPerrigo Company p…BHC logoBHCBausch Health Com…
Analyst RatingConsensus buy/hold/sellHoldHoldBuy
Price TargetConsensus 12-month target$29.50$36.20$8.00
# AnalystsCovering analysts363638
Dividend YieldAnnual dividend ÷ price+9.8%
Dividend StreakConsecutive years of raises102
Dividend / ShareAnnual DPS$1.15
Buyback YieldShare repurchases ÷ mkt cap0.0%+16.0%0.0%0.0%
PRGO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

BHC leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). PCRX leads in 1 (Risk & Volatility). 1 tied.

Best OverallBausch Health Companies Inc. (BHC)Leads 3 of 6 categories
Loading custom metrics...

PRFX vs PCRX vs PRGO vs BHC: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is PRFX or PCRX or PRGO or BHC a better buy right now?

For growth investors, Bausch Health Companies Inc.

(BHC) is the stronger pick with 8. 5% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Bausch Health Companies Inc. (BHC) offers the better valuation at 13. 3x trailing P/E (1. 3x forward), making it the more compelling value choice. Analysts rate Bausch Health Companies Inc. (BHC) a "Buy" — based on 38 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — PRFX or PCRX or PRGO or BHC?

On trailing P/E, Bausch Health Companies Inc.

(BHC) is the cheapest at 13. 3x versus Pacira BioSciences, Inc. at 147. 8x. On forward P/E, Bausch Health Companies Inc. is actually cheaper at 1. 3x.

03

Which is the better long-term investment — PRFX or PCRX or PRGO or BHC?

Over the past 5 years, Perrigo Company plc (PRGO) delivered a total return of -60.

1%, compared to -99. 8% for PainReform Ltd. (PRFX). Over 10 years, the gap is even starker: PCRX returned -52. 2% versus PRFX's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — PRFX or PCRX or PRGO or BHC?

By beta (market sensitivity over 5 years), Pacira BioSciences, Inc.

(PCRX) is the lower-risk stock at 0. 41β versus PainReform Ltd. 's 1. 69β — meaning PRFX is approximately 310% more volatile than PCRX relative to the S&P 500. On balance sheet safety, PainReform Ltd. (PRFX) carries a lower debt/equity ratio of 2% versus 56% for Bausch Health Companies Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — PRFX or PCRX or PRGO or BHC?

By revenue growth (latest reported year), Bausch Health Companies Inc.

(BHC) is pulling ahead at 8. 5% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Bausch Health Companies Inc. grew EPS 430. 8% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, BHC leads at 8. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — PRFX or PCRX or PRGO or BHC?

Bausch Health Companies Inc.

(BHC) is the more profitable company, earning 1. 5% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 1. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BHC leads at 21. 3% versus 0. 0% for PRFX. At the gross margin level — before operating expenses — PCRX leads at 79. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is PRFX or PCRX or PRGO or BHC more undervalued right now?

On forward earnings alone, Bausch Health Companies Inc.

(BHC) trades at 1. 3x forward P/E versus 8. 1x for Pacira BioSciences, Inc. — 6. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 208. 9% to $36. 20.

08

Which pays a better dividend — PRFX or PCRX or PRGO or BHC?

In this comparison, PRGO (9.

8% yield) pays a dividend. PRFX, PCRX, BHC do not pay a meaningful dividend and should not be held primarily for income.

09

Is PRFX or PCRX or PRGO or BHC better for a retirement portfolio?

For long-horizon retirement investors, Pacira BioSciences, Inc.

(PCRX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 41)). PainReform Ltd. (PRFX) carries a higher beta of 1. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PCRX: -52. 2%, PRFX: -99. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between PRFX and PCRX and PRGO and BHC?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: PRFX is a small-cap quality compounder stock; PCRX is a small-cap quality compounder stock; PRGO is a small-cap income-oriented stock; BHC is a small-cap deep-value stock. PRGO pays a dividend while PRFX, PCRX, BHC do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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PRFX

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  • Sector: Healthcare
  • Market Cap > $100B
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  • Market Cap > $100B
  • Revenue Growth > 5%
  • Gross Margin > 36%
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  • Market Cap > $100B
  • Gross Margin > 20%
  • Dividend Yield > 3.9%
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BHC

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  • Sector: Healthcare
  • Market Cap > $100B
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  • Gross Margin > 37%
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