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PainReform Ltd. (PRFX) Total Return Calculator with Dividends Reinvested

PainReform Ltd.

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The total return for PainReform Ltd. (PRFX) stock is -82.08% over the past 12 months. So far it's down 45.56% this year. The 5-year total return is -99.77%, meaning $10,000 invested in PRFX stock 5 years ago would be worth $23 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in PRFX 1 year ago, it would be worth $1,959 today — you'd have lost $8,041.

With Dividends Reinvested$1,959-80.41%

Price Only (No DRIP)$1,959-80.41%

Period2025-05-08 → 2026-05-07

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in PRFX

1Y$1,792-$8,208 (-82.1%)-82.1% CAGR

3Y$96-$9,904 (-99.0%)-78.7% CAGR

5Y$23-$9,977 (-99.8%)-70.3% CAGR

10Y$9-$9,991 (-99.9%)-50.2% CAGR

15Y$9-$9,991 (-99.9%)-37.2% CAGR

20Y$9-$9,991 (-99.9%)-29.4% CAGR

30Y$9-$9,991 (-99.9%)-20.7% CAGR

PainReform Ltd. did not pay dividends during this period. Total return = price return.

Loading PRFX total return...

As of 2026-05-08

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-45.56%	—	-45.56%	—	$5,444
1Y	-82.08%	-82.08%	-82.08%	—	$1,792
3Y	-99.04%	-78.75%	-99.04%	—	$96
5Y	-99.77%	-70.28%	-99.77%	—	$23
10Y	-99.91%	-50.19%	-99.91%	—	$9
15Y	-99.91%	-37.16%	-99.91%	—	$9
20Y	-99.91%	-29.42%	-99.91%	—	$9
30Y	-99.91%	-20.73%	-99.91%	—	$9

Risk & Highlights

Best Year-32.93%2023

Worst Year-80.19%2025

Max Drawdown-93.39%2025-08-19 → 2026-01-24

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-14.90%	-14.90%	—	+0.41%	-15.3pp
2025	-80.19%	-80.19%	—	+16.64%	-96.8pp
2024	-78.33%	-78.33%	—	+24.00%	-102.3pp
2023	-32.93%	-32.93%	—	+24.81%	-57.7pp
2022	-71.32%	-71.32%	—	-19.95%	-51.4pp

PRFX underperformed the S&P 500 by 112.45pp over the past year (-82.08% vs +30.37%).

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PRFX Peers' Total Return

Accurate peer set · 9 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
PRFXPainReform Ltd.	$861,734	-15.6%	-45.6%	-82.1%	—	-99.0%	-99.8%	-99.9%
PCRXPacira BioSciences, Inc.	$930M	+4.9%	-3.4%	-6.1%	—	-44.1%	-62.6%	-51.2%
ACRSAclaris Therapeutics, Inc.	$586M	+29.6%	+68.8%	+288.8%	—	-42.1%	-78.8%	-76.3%
NKTRNektar Therapeutics	$1.7B	+9.4%	+92.0%	+818.2%	—	+621.8%	-72.3%	-59.1%
XTLBXTL Biopharmaceuticals Ltd.	$293,767	+12.2%	+11.3%	-50.9%	—	-45.7%	-80.4%	-87.3%
BHCBausch Health Companies Inc.	$2.1B	+8.8%	-20.6%	+21.8%	—	-4.4%	-79.6%	-79.6%
PRGOPerrigo Company plc	$1.6B	+11.0%	-13.5%	-51.2%	+4.4pp	-58.1%	-60.1%	-77.7%
INVAInnoviva, Inc.	$1.9B	-2.1%	+14.7%	+21.7%	—	+95.2%	+94.4%	+94.9%
DAREDaré Bioscience, Inc.	$25M	+64.4%	+49.2%	+0.7%	—	-75.8%	-82.4%	-99.0%
COLLCollegium Pharmaceutical, Inc.	$1.3B	+20.0%	-13.6%	+45.4%	—	+67.9%	+71.0%	+153.1%

Compare:PRFX vs PCRX PRFX vs ACRS PRFX vs NKTR PRFX vs PCRX vs ACRS

About PRFX Dividend Returns

PainReform Ltd. (PRFX) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of PRFX over the past year?

PainReform Ltd. (PRFX) delivered a return of -82.08% over the past year. Since PRFX does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in PRFX be worth today?

A $10,000 investment in PainReform Ltd. one year ago would be worth $1,792 today, representing a loss of $8,208.

Q3Does PRFX pay dividends?

PainReform Ltd. (PRFX) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For PRFX, the total return equals the price-only return.

Q4Did PRFX beat the S&P 500?

No, PainReform Ltd. (PRFX) underperformed the S&P 500 by 112.45 percentage points over the past year. PRFX delivered a total return of -82.08%, compared to the S&P 500's 30.37%. This means a passive S&P 500 index fund outperformed PRFX by 112.45pp during this period.

Q5What is PRFX's worst drawdown?

PainReform Ltd. (PRFX) experienced a maximum drawdown of -93.39% over the past year, declining from its peak on 2025-08-19 to its trough on 2026-01-24. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is PRFX's long-term total return over 10, 20, or 30 years?

Here are PainReform Ltd. (PRFX)'s long-term returns with dividends reinvested. Over 10 years, the total return is -99.9% (-50.2% CAGR) — $10,000 would have grown to $9. Over 20 years: -99.9% total return (-29.4% CAGR) — $10,000 → $9. Over 30 years: -99.9% total return (-20.7% CAGR) — $10,000 → $9. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was PRFX's best and worst year?

PainReform Ltd.'s best calendar year was 2023 with a total return of -32.9%. Its worst year was 2025 with a total return of -80.2%. This range shows the volatility investors should expect — the difference between the best and worst year is 47.3 percentage points.