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PRPH vs TMO vs DHR vs A

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PRPH
ProPhase Labs, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$5M
5Y Perf.-96.2%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$176.36B
5Y Perf.+35.9%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$124.33B
5Y Perf.+18.9%
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$33.58B
5Y Perf.+34.6%

PRPH vs TMO vs DHR vs A — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PRPH logoPRPH
TMO logoTMO
DHR logoDHR
A logoA
IndustryDrug Manufacturers - Specialty & GenericMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$5M$176.36B$124.33B$33.58B
Revenue (TTM)$1M$45.20B$24.78B$7.07B
Net Income (TTM)$-42M$6.86B$3.69B$1.29B
Gross Margin191.4%39.4%60.7%38.8%
Operating Margin-25.0%17.8%21.0%20.6%
Forward P/E19.1x20.8x19.9x
Total Debt$25M$40.85B$18.42B$3.35B
Cash & Equiv.$678K$9.86B$4.62B$1.79B

PRPH vs TMO vs DHR vs ALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PRPH
TMO
DHR
A
StockMay 20May 26Return
ProPhase Labs, Inc. (PRPH)1003.8-96.2%
Thermo Fisher Scien… (TMO)100135.9+35.9%
Danaher Corporation (DHR)100118.9+18.9%
Agilent Technologie… (A)100134.6+34.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: PRPH vs TMO vs DHR vs A

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: A leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Thermo Fisher Scientific Inc. is the stronger pick specifically for valuation and capital efficiency and recent price momentum and sentiment. DHR also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
PRPH
ProPhase Labs, Inc.
The Secondary Option

PRPH lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 229.1% 10Y total return vs DHR's 219.3%
  • Better valuation composite
  • +16.8% vs PRPH's -58.0%
Best for: long-term compounding
DHR
Danaher Corporation
The Defensive Pick

DHR is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.94, Low D/E 35.1%, current ratio 1.87x
  • Beta 0.94 vs PRPH's 2.28, lower leverage
Best for: sleep-well-at-night
A
Agilent Technologies, Inc.
The Income Pick

A carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 10 yrs, beta 1.23, yield 0.8%
  • Rev growth 6.7%, EPS growth 3.2%, 3Y rev CAGR 0.5%
  • PEG 1.35 vs DHR's 34.35
  • Beta 1.23, yield 0.8%, current ratio 1.96x
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthA logoA6.7% revenue growth vs PRPH's -84.7%
ValueTMO logoTMOBetter valuation composite
Quality / MarginsA logoA18.3% margin vs PRPH's -38.7%
Stability / SafetyDHR logoDHRBeta 0.94 vs PRPH's 2.28, lower leverage
DividendsA logoA0.8% yield, 10-year raise streak, vs TMO's 0.4%, (1 stock pays no dividend)
Momentum (1Y)TMO logoTMO+16.8% vs PRPH's -58.0%
Efficiency (ROA)A logoA10.1% ROA vs PRPH's -63.5%, ROIC 13.5% vs -59.4%

PRPH vs TMO vs DHR vs A — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

PRPHProPhase Labs, Inc.
FY 2024
Consumer Products
100.0%$7M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B
AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B

PRPH vs TMO vs DHR vs A — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLALAGGINGDHR

Income & Cash Flow (Last 12 Months)

Evenly matched — PRPH and DHR and A each lead in 2 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 41965.6x PRPH's $1M. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to PRPH's -38.7%. On growth, A holds the edge at +7.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
RevenueTrailing 12 months$1M$45.2B$24.8B$7.1B
EBITDAEarnings before interest/tax-$22M$10.5B$7.2B$1.7B
Net IncomeAfter-tax profit-$42M$6.9B$3.7B$1.3B
Free Cash FlowCash after capex-$23M$6.7B$5.3B$993M
Gross MarginGross profit ÷ Revenue+191.4%+39.4%+60.7%+38.8%
Operating MarginEBIT ÷ Revenue-25.0%+17.8%+21.0%+20.6%
Net MarginNet income ÷ Revenue-38.7%+15.2%+14.9%+18.3%
FCF MarginFCF ÷ Revenue-21.1%+14.9%+21.4%+14.1%
Rev. Growth (YoY)Latest quarter vs prior year-71.9%+6.2%+3.7%+7.0%
EPS Growth (YoY)Latest quarter vs prior year+54.3%+11.3%+9.8%-3.6%
Evenly matched — PRPH and DHR and A each lead in 2 of 6 comparable metrics.

Valuation Metrics

PRPH leads this category, winning 3 of 7 comparable metrics.

At 26.0x trailing earnings, A trades at a 26% valuation discount to DHR's 34.9x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.76x vs DHR's 34.35x — a lower PEG means you pay less per unit of expected earnings growth.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
Market CapShares × price$5M$176.4B$124.3B$33.6B
Enterprise ValueMkt cap + debt − cash$29M$207.4B$138.1B$35.1B
Trailing P/EPrice ÷ TTM EPS-0.05x26.75x34.85x25.96x
Forward P/EPrice ÷ next-FY EPS est.19.11x20.82x19.87x
PEG RatioP/E ÷ EPS growth rate12.67x34.35x1.76x
EV / EBITDAEnterprise value multiple19.04x18.21x19.89x
Price / SalesMarket cap ÷ Revenue0.74x3.96x5.06x4.83x
Price / BookPrice ÷ Book value/share0.31x3.34x2.38x5.00x
Price / FCFMarket cap ÷ FCF28.02x23.64x29.15x
PRPH leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

A leads this category, winning 5 of 9 comparable metrics.

A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $-6 for PRPH. DHR carries lower financial leverage with a 0.35x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRPH's 3.34x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs PRPH's 1/9, reflecting strong financial health.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
ROE (TTM)Return on equity-6.1%+13.2%+7.1%+18.7%
ROA (TTM)Return on assets-63.5%+6.4%+4.5%+10.1%
ROICReturn on invested capital-59.4%+7.5%+5.9%+13.5%
ROCEReturn on capital employed-75.6%+9.1%+7.0%+14.5%
Piotroski ScoreFundamental quality 0–91675
Debt / EquityFinancial leverage3.34x0.76x0.35x0.50x
Net DebtTotal debt minus cash$24M$31.0B$13.8B$1.6B
Cash & Equiv.Liquid assets$678,000$9.9B$4.6B$1.8B
Total DebtShort + long-term debt$25M$40.9B$18.4B$3.4B
Interest CoverageEBIT ÷ Interest expense-7.96x5.89x18.13x19.53x
A leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — TMO and A each lead in 3 of 6 comparable metrics.

A $10,000 investment in TMO five years ago would be worth $10,283 today (with dividends reinvested), compared to $3,682 for PRPH. Over the past 12 months, TMO leads with a +16.8% total return vs PRPH's -58.0%. The 3-year compound annual growth rate (CAGR) favors A at -2.8% vs PRPH's -69.4% — a key indicator of consistent wealth creation.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
YTD ReturnYear-to-date-66.7%-19.8%-23.6%-13.6%
1-Year ReturnPast 12 months-58.0%+16.8%-8.3%+11.3%
3-Year ReturnCumulative with dividends-97.1%-11.7%-15.5%-8.2%
5-Year ReturnCumulative with dividends-63.2%+2.8%-21.1%-8.0%
10-Year ReturnCumulative with dividends+37.5%+229.1%+219.3%+205.7%
CAGR (3Y)Annualised 3-year return-69.4%-4.0%-5.5%-2.8%
Evenly matched — TMO and A each lead in 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DHR and A each lead in 1 of 2 comparable metrics.

DHR is the less volatile stock with a 0.94 beta — it tends to amplify market swings less than PRPH's 2.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. A currently trades 74.0% from its 52-week high vs PRPH's 6.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
Beta (5Y)Sensitivity to S&P 5002.28x1.10x0.94x1.23x
52-Week HighHighest price in past year$1.84$643.99$242.80$160.27
52-Week LowLowest price in past year$0.07$385.46$172.06$104.79
% of 52W HighCurrent price vs 52-week peak+6.5%+73.7%+72.3%+74.0%
RSI (14)Momentum oscillator 0–10056.843.133.052.5
Avg Volume (50D)Average daily shares traded105K1.9M4.2M2.0M
Evenly matched — DHR and A each lead in 1 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: TMO as "Buy", DHR as "Buy", A as "Buy". Consensus price targets imply 40.6% upside for DHR (target: $247) vs 38.0% for TMO (target: $655). For income investors, A offers the higher dividend yield at 0.84% vs TMO's 0.36%.

MetricPRPH logoPRPHProPhase Labs, In…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$654.67$247.00$166.00
# AnalystsCovering analysts424238
Dividend YieldAnnual dividend ÷ price+0.4%+0.7%+0.8%
Dividend StreakConsecutive years of raises18110
Dividend / ShareAnnual DPS$1.69$1.23$0.99
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%+2.5%+1.3%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

A leads in 2 of 6 categories (Profitability & Efficiency, Analyst Outlook). PRPH leads in 1 (Valuation Metrics). 3 tied.

Best OverallAgilent Technologies, Inc. (A)Leads 2 of 6 categories
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PRPH vs TMO vs DHR vs A: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is PRPH or TMO or DHR or A a better buy right now?

For growth investors, Agilent Technologies, Inc.

(A) is the stronger pick with 6. 7% revenue growth year-over-year, versus -84. 7% for ProPhase Labs, Inc. (PRPH). Agilent Technologies, Inc. (A) offers the better valuation at 26. 0x trailing P/E (19. 9x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — PRPH or TMO or DHR or A?

On trailing P/E, Agilent Technologies, Inc.

(A) is the cheapest at 26. 0x versus Danaher Corporation at 34. 9x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 19. 1x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 35x versus Danaher Corporation's 34. 35x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — PRPH or TMO or DHR or A?

Over the past 5 years, Thermo Fisher Scientific Inc.

(TMO) delivered a total return of +2. 8%, compared to -63. 2% for ProPhase Labs, Inc. (PRPH). Over 10 years, the gap is even starker: TMO returned +229. 1% versus PRPH's +37. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — PRPH or TMO or DHR or A?

By beta (market sensitivity over 5 years), Danaher Corporation (DHR) is the lower-risk stock at 0.

94β versus ProPhase Labs, Inc. 's 2. 28β — meaning PRPH is approximately 142% more volatile than DHR relative to the S&P 500. On balance sheet safety, Danaher Corporation (DHR) carries a lower debt/equity ratio of 35% versus 3% for ProPhase Labs, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — PRPH or TMO or DHR or A?

By revenue growth (latest reported year), Agilent Technologies, Inc.

(A) is pulling ahead at 6. 7% versus -84. 7% for ProPhase Labs, Inc. (PRPH). On earnings-per-share growth, the picture is similar: Thermo Fisher Scientific Inc. grew EPS 7. 3% year-over-year, compared to -166. 3% for ProPhase Labs, Inc.. Over a 3-year CAGR, A leads at 0. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — PRPH or TMO or DHR or A?

Agilent Technologies, Inc.

(A) is the more profitable company, earning 18. 8% net margin versus -788. 2% for ProPhase Labs, Inc. — meaning it keeps 18. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: A leads at 21. 3% versus -570. 6% for PRPH. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is PRPH or TMO or DHR or A more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 35x versus Danaher Corporation's 34. 35x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 19. 1x forward P/E versus 20. 8x for Danaher Corporation — 1. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DHR: 40. 6% to $247. 00.

08

Which pays a better dividend — PRPH or TMO or DHR or A?

In this comparison, A (0.

8% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. PRPH does not pay a meaningful dividend and should not be held primarily for income.

09

Is PRPH or TMO or DHR or A better for a retirement portfolio?

For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

94), 0. 7% yield, +219. 3% 10Y return). ProPhase Labs, Inc. (PRPH) carries a higher beta of 2. 28 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (DHR: +219. 3%, PRPH: +37. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between PRPH and TMO and DHR and A?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

DHR, A pay a dividend while PRPH, TMO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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(PRPH: -71.9% · TMO: 6.2%)

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