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Stock Comparison

REGN vs INCY

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$74.89B
5Y Perf.+17.6%
INCY
Incyte Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$19.95B
5Y Perf.-2.0%

REGN vs INCY — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
REGN logoREGN
INCY logoINCY
IndustryBiotechnologyBiotechnology
Market Cap$74.89B$19.95B
Revenue (TTM)$14.92B$5.36B
Net Income (TTM)$4.42B$1.43B
Gross Margin84.5%91.9%
Operating Margin24.3%26.8%
Forward P/E15.6x13.3x
Total Debt$2.71B$69M
Cash & Equiv.$3.12B$3.10B

REGN vs INCYLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

REGN
INCY
StockMay 20May 26Return
Regeneron Pharmaceu… (REGN)100117.6+17.6%
Incyte Corporation (INCY)10098.0-2.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: REGN vs INCY

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INCY leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Regeneron Pharmaceuticals, Inc. is the stronger pick specifically for profitability and margin quality and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
REGN
Regeneron Pharmaceuticals, Inc.
The Income Pick

REGN is the clearest fit if your priority is income & stability and long-term compounding.

  • Dividend streak 1 yrs, beta 0.81, yield 0.5%
  • 96.0% 10Y total return vs INCY's 41.3%
  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
Best for: income & stability and long-term compounding
INCY
Incyte Corporation
The Growth Play

INCY carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 21.2%, EPS growth 41.7%, 3Y rev CAGR 14.8%
  • 21.2% revenue growth vs REGN's 1.0%
  • Lower P/E (13.3x vs 15.6x)
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthINCY logoINCY21.2% revenue growth vs REGN's 1.0%
ValueINCY logoINCYLower P/E (13.3x vs 15.6x)
Quality / MarginsREGN logoREGN29.6% margin vs INCY's 26.7%
Stability / SafetyREGN logoREGNBeta 0.81 vs INCY's 0.87
DividendsREGN logoREGN0.5% yield; 1-year raise streak; the other pay no meaningful dividend
Momentum (1Y)INCY logoINCY+67.5% vs REGN's +29.7%
Efficiency (ROA)INCY logoINCY21.7% ROA vs REGN's 11.1%, ROIC 51.1% vs 8.9%

REGN vs INCY — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
INCYIncyte Corporation
FY 2025
J A K A F I
71.3%$3.6B
OPZELURA
13.6%$678M
Milestone And Contract Revenue
3.0%$150M
Olumiant Royalty
2.9%$145M
M I N J U V I
2.9%$145M
I C L U S I G
2.7%$134M
PEMAZYRE Royalty Revenues
1.7%$87M
Other (2)
1.9%$93M

REGN vs INCY — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINCYLAGGINGREGN

Income & Cash Flow (Last 12 Months)

INCY leads this category, winning 4 of 6 comparable metrics.

REGN is the larger business by revenue, generating $14.9B annually — 2.8x INCY's $5.4B. Profitability is closely matched — net margins range from 29.6% (REGN) to 26.7% (INCY).

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
RevenueTrailing 12 months$14.9B$5.4B
EBITDAEarnings before interest/tax$4.2B$1.5B
Net IncomeAfter-tax profit$4.4B$1.4B
Free Cash FlowCash after capex$4.2B$1.5B
Gross MarginGross profit ÷ Revenue+84.5%+91.9%
Operating MarginEBIT ÷ Revenue+24.3%+26.8%
Net MarginNet income ÷ Revenue+29.6%+26.7%
FCF MarginFCF ÷ Revenue+27.9%+27.1%
Rev. Growth (YoY)Latest quarter vs prior year+19.0%+20.9%
EPS Growth (YoY)Latest quarter vs prior year-7.2%+83.8%
INCY leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

INCY leads this category, winning 5 of 6 comparable metrics.

At 15.6x trailing earnings, INCY trades at a 10% valuation discount to REGN's 17.4x P/E. On an enterprise value basis, INCY's 11.8x EV/EBITDA is more attractive than REGN's 18.1x.

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
Market CapShares × price$74.9B$19.9B
Enterprise ValueMkt cap + debt − cash$74.5B$16.9B
Trailing P/EPrice ÷ TTM EPS17.38x15.58x
Forward P/EPrice ÷ next-FY EPS est.15.60x13.34x
PEG RatioP/E ÷ EPS growth rate2.75x
EV / EBITDAEnterprise value multiple18.07x11.78x
Price / SalesMarket cap ÷ Revenue5.22x3.88x
Price / BookPrice ÷ Book value/share2.50x3.88x
Price / FCFMarket cap ÷ FCF18.35x14.73x
INCY leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

INCY leads this category, winning 9 of 9 comparable metrics.

INCY delivers a 29.3% return on equity — every $100 of shareholder capital generates $29 in annual profit, vs $14 for REGN. INCY carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to REGN's 0.09x. On the Piotroski fundamental quality scale (0–9), INCY scores 7/9 vs REGN's 5/9, reflecting strong financial health.

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
ROE (TTM)Return on equity+14.3%+29.3%
ROA (TTM)Return on assets+11.1%+21.7%
ROICReturn on invested capital+8.9%+51.1%
ROCEReturn on capital employed+10.2%+29.0%
Piotroski ScoreFundamental quality 0–957
Debt / EquityFinancial leverage0.09x0.01x
Net DebtTotal debt minus cash-$412M-$3.0B
Cash & Equiv.Liquid assets$3.1B$3.1B
Total DebtShort + long-term debt$2.7B$69M
Interest CoverageEBIT ÷ Interest expense108.44x759.79x
INCY leads this category, winning 9 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INCY leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in REGN five years ago would be worth $14,543 today (with dividends reinvested), compared to $12,131 for INCY. Over the past 12 months, INCY leads with a +67.5% total return vs REGN's +29.7%. The 3-year compound annual growth rate (CAGR) favors INCY at 14.9% vs REGN's -1.2% — a key indicator of consistent wealth creation.

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
YTD ReturnYear-to-date-7.0%-1.5%
1-Year ReturnPast 12 months+29.7%+67.5%
3-Year ReturnCumulative with dividends-3.6%+51.8%
5-Year ReturnCumulative with dividends+45.4%+21.3%
10-Year ReturnCumulative with dividends+96.0%+41.3%
CAGR (3Y)Annualised 3-year return-1.2%+14.9%
INCY leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — REGN and INCY each lead in 1 of 2 comparable metrics.

REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than INCY's 0.87 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
Beta (5Y)Sensitivity to S&P 5000.81x0.87x
52-Week HighHighest price in past year$821.11$112.29
52-Week LowLowest price in past year$476.49$57.77
% of 52W HighCurrent price vs 52-week peak+87.8%+88.9%
RSI (14)Momentum oscillator 0–10037.953.7
Avg Volume (50D)Average daily shares traded634K1.5M
Evenly matched — REGN and INCY each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates REGN as "Buy" and INCY as "Buy". Consensus price targets imply 20.1% upside for REGN (target: $866) vs 9.7% for INCY (target: $110). REGN is the only dividend payer here at 0.47% yield — a key consideration for income-focused portfolios.

MetricREGN logoREGNRegeneron Pharmac…INCY logoINCYIncyte Corporation
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$865.68$109.50
# AnalystsCovering analysts4844
Dividend YieldAnnual dividend ÷ price+0.5%
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS$3.41
Buyback YieldShare repurchases ÷ mkt cap+5.3%+0.1%
Insufficient data to determine a leader in this category.
Key Takeaway

INCY leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.

Best OverallIncyte Corporation (INCY)Leads 4 of 6 categories
Loading custom metrics...

REGN vs INCY: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is REGN or INCY a better buy right now?

For growth investors, Incyte Corporation (INCY) is the stronger pick with 21.

2% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Incyte Corporation (INCY) offers the better valuation at 15. 6x trailing P/E (13. 3x forward), making it the more compelling value choice. Analysts rate Regeneron Pharmaceuticals, Inc. (REGN) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — REGN or INCY?

On trailing P/E, Incyte Corporation (INCY) is the cheapest at 15.

6x versus Regeneron Pharmaceuticals, Inc. at 17. 4x. On forward P/E, Incyte Corporation is actually cheaper at 13. 3x.

03

Which is the better long-term investment — REGN or INCY?

Over the past 5 years, Regeneron Pharmaceuticals, Inc.

(REGN) delivered a total return of +45. 4%, compared to +21. 3% for Incyte Corporation (INCY). Over 10 years, the gap is even starker: REGN returned +96. 0% versus INCY's +41. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — REGN or INCY?

By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.

(REGN) is the lower-risk stock at 0. 81β versus Incyte Corporation's 0. 87β — meaning INCY is approximately 9% more volatile than REGN relative to the S&P 500. On balance sheet safety, Incyte Corporation (INCY) carries a lower debt/equity ratio of 1% versus 9% for Regeneron Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — REGN or INCY?

By revenue growth (latest reported year), Incyte Corporation (INCY) is pulling ahead at 21.

2% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Incyte Corporation grew EPS 41. 7% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Over a 3-year CAGR, INCY leads at 14. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — REGN or INCY?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus 25. 0% for Incyte Corporation — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INCY leads at 26. 1% versus 24. 9% for REGN. At the gross margin level — before operating expenses — INCY leads at 91. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is REGN or INCY more undervalued right now?

On forward earnings alone, Incyte Corporation (INCY) trades at 13.

3x forward P/E versus 15. 6x for Regeneron Pharmaceuticals, Inc. — 2. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for REGN: 20. 1% to $865. 68.

08

Which pays a better dividend — REGN or INCY?

In this comparison, REGN (0.

5% yield) pays a dividend. INCY does not pay a meaningful dividend and should not be held primarily for income.

09

Is REGN or INCY better for a retirement portfolio?

For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.

(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Both have compounded well over 10 years (REGN: +96. 0%, INCY: +41. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between REGN and INCY?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: REGN is a mid-cap deep-value stock; INCY is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

Stocks Like

REGN

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
  • Net Margin > 17%
Run This Screen
Stocks Like

INCY

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 10%
  • Net Margin > 16%
Run This Screen
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Beat Both

Find stocks that outperform REGN and INCY on the metrics below

Revenue Growth>
%
(REGN: 19.0% · INCY: 20.9%)
Net Margin>
%
(REGN: 29.6% · INCY: 26.7%)
P/E Ratio<
x
(REGN: 17.4x · INCY: 15.6x)

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