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RGEN vs FTRE vs NTRA vs AZTA vs BRKR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
RGEN
Repligen Corporation

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$7.13B
5Y Perf.-10.6%
FTRE
Fortrea Holdings Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.47B
5Y Perf.-54.2%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$31.16B
5Y Perf.+351.7%
AZTA
Azenta, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$855M
5Y Perf.-60.2%
BRKR
Bruker Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$6.66B
5Y Perf.-40.8%

RGEN vs FTRE vs NTRA vs AZTA vs BRKR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
RGEN logoRGEN
FTRE logoFTRE
NTRA logoNTRA
AZTA logoAZTA
BRKR logoBRKR
IndustryMedical - Instruments & SuppliesBiotechnologyMedical - Diagnostics & ResearchMedical - Instruments & SuppliesMedical - Devices
Market Cap$7.13B$1.47B$31.16B$855M$6.66B
Revenue (TTM)$763M$2.71B$2.31B$597M$3.46B
Net Income (TTM)$51M$-447M$-208M$-178M$-12M
Gross Margin51.5%12.1%64.8%44.6%45.3%
Operating Margin8.7%-1.1%-13.4%-26.4%4.9%
Forward P/E64.3x23.0x23.7x20.7x
Total Debt$690M$68M$214M$111M$2.04B
Cash & Equiv.$566M$175M$1.08B$280M$299M

RGEN vs FTRE vs NTRA vs AZTA vs BRKRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

RGEN
FTRE
NTRA
AZTA
BRKR
StockJun 23May 26Return
Repligen Corporation (RGEN)10089.4-10.6%
Fortrea Holdings In… (FTRE)10045.8-54.2%
Natera, Inc. (NTRA)100451.7+351.7%
Azenta, Inc. (AZTA)10039.8-60.2%
Bruker Corporation (BRKR)10059.2-40.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: RGEN vs FTRE vs NTRA vs AZTA vs BRKR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RGEN and NTRA are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Natera, Inc. is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. BRKR and FTRE also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
RGEN
Repligen Corporation
The Quality Compounder

RGEN has the current edge in this matchup, primarily because of its strength in quality and efficiency.

  • 6.7% margin vs AZTA's -29.9%
  • 1.8% ROA vs FTRE's -16.3%, ROIC 2.2% vs -1.6%
Best for: quality and efficiency
FTRE
Fortrea Holdings Inc.
The Momentum Pick

FTRE is the clearest fit if your priority is momentum.

  • +176.6% vs AZTA's -26.5%
Best for: momentum
NTRA
Natera, Inc.
The Growth Play

NTRA is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 20.9% 10Y total return vs RGEN's 369.1%
  • Lower volatility, beta 1.26, Low D/E 12.5%, current ratio 3.39x
  • Beta 1.26, current ratio 3.39x
Best for: growth exposure and long-term compounding
AZTA
Azenta, Inc.
The Income Pick

AZTA is the clearest fit if your priority is income & stability.

  • Dividend streak 0 yrs, beta 2.17
Best for: income & stability
BRKR
Bruker Corporation
The Value Play

BRKR ranks third and is worth considering specifically for value and dividends.

  • Lower P/E (20.7x vs 23.7x)
  • 0.3% yield; the other 4 pay no meaningful dividend
Best for: value and dividends
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs FTRE's 1.0%
ValueBRKR logoBRKRLower P/E (20.7x vs 23.7x)
Quality / MarginsRGEN logoRGEN6.7% margin vs AZTA's -29.9%
Stability / SafetyNTRA logoNTRABeta 1.26 vs FTRE's 2.35
DividendsBRKR logoBRKR0.3% yield; the other 4 pay no meaningful dividend
Momentum (1Y)FTRE logoFTRE+176.6% vs AZTA's -26.5%
Efficiency (ROA)RGEN logoRGEN1.8% ROA vs FTRE's -16.3%, ROIC 2.2% vs -1.6%

RGEN vs FTRE vs NTRA vs AZTA vs BRKR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

RGENRepligen Corporation
FY 2025
Product
50.0%$738M
Filtration Products
27.3%$403M
Chromatography Products
10.4%$153M
Proteins Products
6.6%$97M
Process Analytics Products
5.5%$81M
Other products
0.2%$3M
FTREFortrea Holdings Inc.
FY 2025
Clinical Services Segment
100.0%$2.7B
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M
AZTAAzenta, Inc.
FY 2025
Service
70.8%$421M
Product
29.2%$173M
BRKRBruker Corporation
FY 2025
Product
80.5%$2.8B
Product and Service, Other
19.5%$670M

RGEN vs FTRE vs NTRA vs AZTA vs BRKR — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNTRALAGGINGBRKR

Income & Cash Flow (Last 12 Months)

Evenly matched — RGEN and NTRA each lead in 3 of 6 comparable metrics.

BRKR is the larger business by revenue, generating $3.5B annually — 5.8x AZTA's $597M. RGEN is the more profitable business, keeping 6.7% of every revenue dollar as net income compared to AZTA's -29.9%. On growth, NTRA holds the edge at +39.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
RevenueTrailing 12 months$763M$2.7B$2.3B$597M$3.5B
EBITDAEarnings before interest/tax$155M$48M-$310M-$115M$397M
Net IncomeAfter-tax profit$51M-$447M-$208M-$178M-$12M
Free Cash FlowCash after capex$104M$215M$97M$29M$51M
Gross MarginGross profit ÷ Revenue+51.5%+12.1%+64.8%+44.6%+45.3%
Operating MarginEBIT ÷ Revenue+8.7%-1.1%-13.4%-26.4%+4.9%
Net MarginNet income ÷ Revenue+6.7%-16.5%-9.0%-29.9%-0.3%
FCF MarginFCF ÷ Revenue+13.7%+8.0%+4.2%+4.8%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year+14.8%-2.3%+39.8%+1.0%+2.7%
EPS Growth (YoY)Latest quarter vs prior year+50.0%+95.9%+185.4%-3.0%-79.2%
Evenly matched — RGEN and NTRA each lead in 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — FTRE and AZTA and BRKR each lead in 2 of 6 comparable metrics.

On an enterprise value basis, AZTA's 13.8x EV/EBITDA is more attractive than RGEN's 52.4x.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
Market CapShares × price$7.1B$1.5B$31.2B$855M$6.7B
Enterprise ValueMkt cap + debt − cash$7.3B$1.4B$30.3B$687M$8.4B
Trailing P/EPrice ÷ TTM EPS147.01x-1.44x-144.62x-15.22x-291.53x
Forward P/EPrice ÷ next-FY EPS est.64.26x23.00x23.68x20.68x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple52.45x28.82x13.75x18.41x
Price / SalesMarket cap ÷ Revenue9.66x0.54x13.51x1.44x1.94x
Price / BookPrice ÷ Book value/share3.40x2.52x17.55x0.49x2.64x
Price / FCFMarket cap ÷ FCF75.94x16.68x285.53x22.32x153.73x
Evenly matched — FTRE and AZTA and BRKR each lead in 2 of 6 comparable metrics.

Profitability & Efficiency

RGEN leads this category, winning 4 of 9 comparable metrics.

RGEN delivers a 2.5% return on equity — every $100 of shareholder capital generates $2 in annual profit, vs $-79 for FTRE. AZTA carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to BRKR's 0.81x. On the Piotroski fundamental quality scale (0–9), RGEN scores 7/9 vs BRKR's 4/9, reflecting strong financial health.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
ROE (TTM)Return on equity+2.5%-79.1%-15.3%-10.7%-0.5%
ROA (TTM)Return on assets+1.8%-16.3%-10.6%-8.8%-0.2%
ROICReturn on invested capital+2.2%-1.6%-36.1%-0.5%+4.4%
ROCEReturn on capital employed+2.2%-1.4%-18.3%-0.6%+5.0%
Piotroski ScoreFundamental quality 0–974564
Debt / EquityFinancial leverage0.33x0.12x0.13x0.06x0.81x
Net DebtTotal debt minus cash$124M-$107M-$862M-$169M$1.7B
Cash & Equiv.Liquid assets$566M$175M$1.1B$280M$299M
Total DebtShort + long-term debt$690M$68M$214M$111M$2.0B
Interest CoverageEBIT ÷ Interest expense2.64x-7.33x-25.21x1.14x
RGEN leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $1,903 for AZTA. Over the past 12 months, FTRE leads with a +176.6% total return vs AZTA's -26.5%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs AZTA's -25.8% — a key indicator of consistent wealth creation.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
YTD ReturnYear-to-date-23.1%-7.4%-3.9%-44.4%-9.0%
1-Year ReturnPast 12 months-0.4%+176.6%+37.3%-26.5%+7.8%
3-Year ReturnCumulative with dividends-19.3%-51.3%+314.0%-59.1%-42.5%
5-Year ReturnCumulative with dividends-32.7%-51.3%+115.9%-81.0%-35.5%
10-Year ReturnCumulative with dividends+369.1%-51.3%+2089.4%+123.4%+67.1%
CAGR (3Y)Annualised 3-year return-6.9%-21.3%+60.6%-25.8%-16.9%
NTRA leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

NTRA leads this category, winning 2 of 2 comparable metrics.

NTRA is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than FTRE's 2.35 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 85.7% from its 52-week high vs AZTA's 44.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
Beta (5Y)Sensitivity to S&P 5001.76x2.35x1.26x2.17x1.59x
52-Week HighHighest price in past year$175.77$18.67$256.36$41.73$56.22
52-Week LowLowest price in past year$109.52$3.97$131.81$17.11$28.53
% of 52W HighCurrent price vs 52-week peak+71.9%+83.4%+85.7%+44.5%+77.8%
RSI (14)Momentum oscillator 0–10055.182.857.131.164.8
Avg Volume (50D)Average daily shares traded905K1.4M1.3M1.0M1.9M
NTRA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: RGEN as "Buy", FTRE as "Hold", NTRA as "Buy", AZTA as "Buy", BRKR as "Buy". Consensus price targets imply 140.5% upside for AZTA (target: $45) vs 19.2% for BRKR (target: $52). BRKR is the only dividend payer here at 0.34% yield — a key consideration for income-focused portfolios.

MetricRGEN logoRGENRepligen Corporat…FTRE logoFTREFortrea Holdings …NTRA logoNTRANatera, Inc.AZTA logoAZTAAzenta, Inc.BRKR logoBRKRBruker Corporation
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuyBuy
Price TargetConsensus 12-month target$168.00$18.83$262.50$44.67$52.13
# AnalystsCovering analysts2312271232
Dividend YieldAnnual dividend ÷ price+0.3%
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS$0.15
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

NTRA leads in 2 of 6 categories (Total Returns, Risk & Volatility). RGEN leads in 1 (Profitability & Efficiency). 2 tied.

Best OverallNatera, Inc. (NTRA)Leads 2 of 6 categories
Loading custom metrics...

RGEN vs FTRE vs NTRA vs AZTA vs BRKR: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is RGEN or FTRE or NTRA or AZTA or BRKR a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 1. 0% for Fortrea Holdings Inc. (FTRE). Repligen Corporation (RGEN) offers the better valuation at 147. 0x trailing P/E (64. 3x forward), making it the more compelling value choice. Analysts rate Repligen Corporation (RGEN) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — RGEN or FTRE or NTRA or AZTA or BRKR?

On forward P/E, Bruker Corporation is actually cheaper at 20.

7x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — RGEN or FTRE or NTRA or AZTA or BRKR?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +115. 9%, compared to -81. 0% for Azenta, Inc. (AZTA). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus FTRE's -51. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — RGEN or FTRE or NTRA or AZTA or BRKR?

By beta (market sensitivity over 5 years), Natera, Inc.

(NTRA) is the lower-risk stock at 1. 26β versus Fortrea Holdings Inc. 's 2. 35β — meaning FTRE is approximately 87% more volatile than NTRA relative to the S&P 500. On balance sheet safety, Azenta, Inc. (AZTA) carries a lower debt/equity ratio of 6% versus 81% for Bruker Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — RGEN or FTRE or NTRA or AZTA or BRKR?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus 1. 0% for Fortrea Holdings Inc. (FTRE). On earnings-per-share growth, the picture is similar: Repligen Corporation grew EPS 287. 0% year-over-year, compared to -194. 6% for Fortrea Holdings Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — RGEN or FTRE or NTRA or AZTA or BRKR?

Repligen Corporation (RGEN) is the more profitable company, earning 6.

6% net margin versus -36. 2% for Fortrea Holdings Inc. — meaning it keeps 6. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RGEN leads at 8. 1% versus -13. 4% for NTRA. At the gross margin level — before operating expenses — NTRA leads at 64. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is RGEN or FTRE or NTRA or AZTA or BRKR more undervalued right now?

On forward earnings alone, Bruker Corporation (BRKR) trades at 20.

7x forward P/E versus 64. 3x for Repligen Corporation — 43. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AZTA: 140. 5% to $44. 67.

08

Which pays a better dividend — RGEN or FTRE or NTRA or AZTA or BRKR?

In this comparison, BRKR (0.

3% yield) pays a dividend. RGEN, FTRE, NTRA, AZTA do not pay a meaningful dividend and should not be held primarily for income.

09

Is RGEN or FTRE or NTRA or AZTA or BRKR better for a retirement portfolio?

For long-horizon retirement investors, Natera, Inc.

(NTRA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 26)). Fortrea Holdings Inc. (FTRE) carries a higher beta of 2. 35 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NTRA: +20. 9%, FTRE: -51. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between RGEN and FTRE and NTRA and AZTA and BRKR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: RGEN is a small-cap high-growth stock; FTRE is a small-cap quality compounder stock; NTRA is a mid-cap high-growth stock; AZTA is a small-cap quality compounder stock; BRKR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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RGEN

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  • Market Cap > $100B
  • Revenue Growth > 7%
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  • Revenue Growth > 19%
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  • Sector: Healthcare
  • Market Cap > $100B
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(RGEN: 14.8% · FTRE: -2.3%)

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