Drug Manufacturers - Specialty & Generic
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RMTI vs DBVT vs PRGO vs HALO vs INVA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Biotechnology
Biotechnology
RMTI vs DBVT vs PRGO vs HALO vs INVA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology |
| Market Cap | $31M | $1712.35T | $1.61B | $7.68B | $1.93B |
| Revenue (TTM) | $17.39B | $0.00 | $4.18B | $1.40B | $424M |
| Net Income (TTM) | $-1.61B | $-168M | $-1.82B | $317M | $504M |
| Gross Margin | 16.7% | — | 34.2% | 81.9% | 76.2% |
| Operating Margin | -8.5% | — | -4.1% | 58.4% | 14.8% |
| Forward P/E | — | — | 5.6x | 8.1x | 11.9x |
| Total Debt | $12M | $22M | $3.97B | $0.00 | $269M |
| Cash & Equiv. | $16M | $194M | $532M | $134M | $551M |
RMTI vs DBVT vs PRGO vs HALO vs INVA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Rockwell Medical, I… (RMTI) | 100 | 3.3 | -96.7% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Perrigo Company plc (PRGO) | 100 | 21.4 | -78.6% |
| Halozyme Therapeuti… (HALO) | 100 | 268.6 | +168.6% |
| Innoviva, Inc. (INVA) | 100 | 163.2 | +63.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RMTI vs DBVT vs PRGO vs HALO vs INVA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 5 stocks, RMTI doesn't own a clear edge in any measured category.
DBVT ranks third and is worth considering specifically for momentum.
- +110.4% vs PRGO's -51.2%
PRGO is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Better valuation composite
- 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend
HALO is the clearest fit if your priority is growth exposure and long-term compounding.
- Rev growth 37.6%, EPS growth -25.4%, 3Y rev CAGR 28.4%
- 5.7% 10Y total return vs INVA's 94.9%
- PEG 0.35 vs INVA's 1.15
- 37.6% revenue growth vs DBVT's -100.0%
INVA carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.
- Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
- 118.9% margin vs PRGO's -43.5%
- Beta 0.13 vs DBVT's 1.26
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 37.6% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 118.9% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.13 vs DBVT's 1.26 | |
| Dividends | 9.8% yield; 10-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs PRGO's -51.2% | |
| Efficiency (ROA) | 32.4% ROA vs RMTI's -28.6%, ROIC 14.2% vs -11.0% |
RMTI vs DBVT vs PRGO vs HALO vs INVA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
RMTI vs DBVT vs PRGO vs HALO vs INVA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
PRGO leads 2 • INVA leads 1 • RMTI leads 0 • DBVT leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RMTI and DBVT operate at a comparable scale, with $17.4B and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, RMTI holds the edge at +915.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $17.4B | $0 | $4.2B | $1.4B | $424M |
| EBITDAEarnings before interest/tax | -$1.5B | -$112M | $58M | $945M | $86M |
| Net IncomeAfter-tax profit | -$1.6B | -$168M | -$1.8B | $317M | $504M |
| Free Cash FlowCash after capex | $2M | -$151M | $108M | $645M | $181M |
| Gross MarginGross profit ÷ Revenue | +16.7% | — | +34.2% | +81.9% | +76.2% |
| Operating MarginEBIT ÷ Revenue | -8.5% | — | -4.1% | +58.4% | +14.8% |
| Net MarginNet income ÷ Revenue | -9.3% | — | -43.5% | +22.7% | +118.9% |
| FCF MarginFCF ÷ Revenue | +0.0% | — | +2.6% | +46.2% | +42.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | +915.6% | — | -7.2% | +51.6% | +10.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +9.9% | +91.5% | -56.4% | -2.1% | +4.0% |
Valuation Metrics
PRGO leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 73% valuation discount to HALO's 25.5x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs HALO's 1.11x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $31M | $1712.35T | $1.6B | $7.7B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $28M | $1712.35T | $5.1B | $7.5B | $1.7B |
| Trailing P/EPrice ÷ TTM EPS | -5.21x | -0.76x | -1.14x | 25.46x | 6.91x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 5.56x | 8.09x | 11.91x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 1.11x | 0.67x |
| EV / EBITDAEnterprise value multiple | — | — | 7.42x | 8.34x | 8.10x |
| Price / SalesMarket cap ÷ Revenue | 0.44x | — | 0.38x | 5.50x | 4.55x |
| Price / BookPrice ÷ Book value/share | 0.76x | 0.66x | 0.55x | 165.47x | 1.65x |
| Price / FCFMarket cap ÷ FCF | — | — | 11.12x | 11.91x | 9.88x |
Profitability & Efficiency
HALO leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-46 for RMTI. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs RMTI's 3/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -45.9% | -130.2% | -50.7% | +6.5% | +46.5% |
| ROA (TTM)Return on assets | -28.6% | -89.0% | -19.8% | +12.5% | +32.4% |
| ROICReturn on invested capital | -11.0% | — | +3.7% | +73.4% | +14.2% |
| ROCEReturn on capital employed | -10.1% | -145.7% | +4.3% | +38.2% | +12.4% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 4 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.34x | 0.13x | 1.35x | — | 0.23x |
| Net DebtTotal debt minus cash | -$3M | -$172M | $3.4B | -$134M | -$282M |
| Cash & Equiv.Liquid assets | $16M | $194M | $532M | $134M | $551M |
| Total DebtShort + long-term debt | $12M | $22M | $4.0B | $0 | $269M |
| Interest CoverageEBIT ÷ Interest expense | -0.01x | -189.82x | -7.20x | 46.08x | 63.45x |
Total Returns (Dividends Reinvested)
HALO leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $763 for RMTI. Over the past 12 months, DBVT leads with a +110.4% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs RMTI's -35.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -9.2% | +4.9% | -13.5% | -7.3% | +14.7% |
| 1-Year ReturnPast 12 months | -30.3% | +110.4% | -51.2% | -7.1% | +21.7% |
| 3-Year ReturnCumulative with dividends | -72.8% | +19.7% | -58.1% | +115.3% | +95.2% |
| 5-Year ReturnCumulative with dividends | -92.4% | -69.1% | -60.1% | +37.0% | +94.4% |
| 10-Year ReturnCumulative with dividends | -99.0% | -87.0% | -77.7% | +570.7% | +94.9% |
| CAGR (3Y)Annualised 3-year return | -35.2% | +6.2% | -25.2% | +29.1% | +25.0% |
Risk & Volatility
INVA leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs RMTI's 37.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.22x | 1.26x | 1.18x | 0.56x | 0.13x |
| 52-Week HighHighest price in past year | $2.10 | $26.18 | $28.44 | $82.22 | $25.15 |
| 52-Week LowLowest price in past year | $0.74 | $7.53 | $9.23 | $47.50 | $16.52 |
| % of 52W HighCurrent price vs 52-week peak | +37.2% | +76.3% | +41.2% | +79.3% | +90.7% |
| RSI (14)Momentum oscillator 0–100 | 35.7 | 48.1 | 60.9 | 52.4 | 39.9 |
| Avg Volume (50D)Average daily shares traded | 259K | 252K | 3.4M | 1.4M | 621K |
Analyst Outlook
PRGO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", PRGO as "Hold", HALO as "Buy", INVA as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 20.2% for HALO (target: $78). PRGO is the only dividend payer here at 9.81% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $20.00 | $78.33 | $37.67 |
| # AnalystsCovering analysts | — | 15 | 36 | 27 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.8% | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 10 | — | 0 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +4.5% | +0.2% |
HALO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRGO leads in 2 (Valuation Metrics, Analyst Outlook).
RMTI vs DBVT vs PRGO vs HALO vs INVA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is RMTI or DBVT or PRGO or HALO or INVA a better buy right now?
For growth investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus -31. 8% for Rockwell Medical, Inc. (RMTI). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — RMTI or DBVT or PRGO or HALO or INVA?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Halozyme Therapeutics, Inc. at 25. 5x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Innoviva, Inc. 's 1. 15x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — RMTI or DBVT or PRGO or HALO or INVA?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -92. 4% for Rockwell Medical, Inc. (RMTI). Over 10 years, the gap is even starker: HALO returned +570. 7% versus RMTI's -99. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — RMTI or DBVT or PRGO or HALO or INVA?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 897% more volatile than INVA relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — RMTI or DBVT or PRGO or HALO or INVA?
By revenue growth (latest reported year), Halozyme Therapeutics, Inc.
(HALO) is pulling ahead at 37. 6% versus -31. 8% for Rockwell Medical, Inc. (RMTI). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — RMTI or DBVT or PRGO or HALO or INVA?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -6. 8% for RMTI. At the gross margin level — before operating expenses — HALO leads at 78. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is RMTI or DBVT or PRGO or HALO or INVA more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Innoviva, Inc. 's 1. 15x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 6x forward P/E versus 11. 9x for Innoviva, Inc. — 6. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — RMTI or DBVT or PRGO or HALO or INVA?
In this comparison, PRGO (9.
8% yield) pays a dividend. RMTI, DBVT, HALO, INVA do not pay a meaningful dividend and should not be held primarily for income.
09Is RMTI or DBVT or PRGO or HALO or INVA better for a retirement portfolio?
For long-horizon retirement investors, Innoviva, Inc.
(INVA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 13)). Both have compounded well over 10 years (INVA: +94. 9%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between RMTI and DBVT and PRGO and HALO and INVA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RMTI is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; PRGO is a small-cap income-oriented stock; HALO is a small-cap high-growth stock; INVA is a small-cap high-growth stock. PRGO pays a dividend while RMTI, DBVT, HALO, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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