Biotechnology
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4 / 10Stock Comparison
RPRX vs DBVT vs REGN vs ABBV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
RPRX vs DBVT vs REGN vs ABBV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General |
| Market Cap | $21.52B | $1712.35T | $73.68B | $358.42B |
| Revenue (TTM) | $2.44B | $0.00 | $14.92B | $61.16B |
| Net Income (TTM) | $828M | $-168M | $4.42B | $4.23B |
| Gross Margin | 74.1% | — | 84.5% | 70.2% |
| Operating Margin | 65.1% | — | 24.3% | 26.7% |
| Forward P/E | 10.3x | — | 15.3x | 14.3x |
| Total Debt | $8.95B | $22M | $2.71B | $69.07B |
| Cash & Equiv. | $619M | $194M | $3.12B | $5.23B |
RPRX vs DBVT vs REGN vs ABBV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | May 26 | Return |
|---|---|---|---|
| Royalty Pharma plc (RPRX) | 100 | 103.4 | +3.4% |
| DBV Technologies S.… (DBVT) | 100 | 45.5 | -54.5% |
| Regeneron Pharmaceu… (REGN) | 100 | 113.7 | +13.7% |
| AbbVie Inc. (ABBV) | 100 | 206.4 | +106.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: RPRX vs DBVT vs REGN vs ABBV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
RPRX is the #2 pick in this set and the best alternative if valuation efficiency is your priority.
- PEG 1.45 vs REGN's 2.43
- Lower P/E (10.3x vs 14.3x)
- 33.9% margin vs DBVT's 0.3%
DBVT is the clearest fit if your priority is momentum.
- +110.4% vs ABBV's +11.3%
REGN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- 11.1% ROA vs DBVT's -89.0%
ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
- 295.5% 10Y total return vs REGN's 90.0%
- Beta 0.34, yield 3.2%, current ratio 0.67x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (10.3x vs 14.3x) | |
| Quality / Margins | 33.9% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.34 vs DBVT's 1.26 | |
| Dividends | 3.2% yield, 13-year raise streak, vs RPRX's 1.3%, (1 stock pays no dividend) | |
| Momentum (1Y) | +110.4% vs ABBV's +11.3% | |
| Efficiency (ROA) | 11.1% ROA vs DBVT's -89.0% |
RPRX vs DBVT vs REGN vs ABBV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
RPRX vs DBVT vs REGN vs ABBV — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ABBV leads in 2 of 6 categories
RPRX leads 1 • DBVT leads 0 • REGN leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RPRX leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV and DBVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. RPRX is the more profitable business, keeping 33.9% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $2.4B | $0 | $14.9B | $61.2B |
| EBITDAEarnings before interest/tax | $1.5B | -$112M | $4.2B | $24.5B |
| Net IncomeAfter-tax profit | $828M | -$168M | $4.4B | $4.2B |
| Free Cash FlowCash after capex | $2.6B | -$151M | $4.2B | $18.7B |
| Gross MarginGross profit ÷ Revenue | +74.1% | — | +84.5% | +70.2% |
| Operating MarginEBIT ÷ Revenue | +65.1% | — | +24.3% | +26.7% |
| Net MarginNet income ÷ Revenue | +33.9% | — | +29.6% | +6.9% |
| FCF MarginFCF ÷ Revenue | +107.0% | — | +27.9% | +30.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | +11.0% | — | +19.0% | +10.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -100.0% | +91.5% | -7.2% | +57.4% |
Valuation Metrics
Evenly matched — RPRX and DBVT and REGN each lead in 2 of 7 comparable metrics.
Valuation Metrics
At 17.1x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), REGN offers better value at 2.70x vs RPRX's 3.95x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $21.5B | $1712.35T | $73.7B | $358.4B |
| Enterprise ValueMkt cap + debt − cash | $29.9B | $1712.35T | $73.3B | $422.3B |
| Trailing P/EPrice ÷ TTM EPS | 27.89x | -0.76x | 17.09x | 85.50x |
| Forward P/EPrice ÷ next-FY EPS est. | 10.26x | — | 15.35x | 14.28x |
| PEG RatioP/E ÷ EPS growth rate | 3.95x | — | 2.70x | — |
| EV / EBITDAEnterprise value multiple | 19.09x | — | 17.78x | 14.96x |
| Price / SalesMarket cap ÷ Revenue | 9.05x | — | 5.14x | 5.86x |
| Price / BookPrice ÷ Book value/share | 2.89x | 0.66x | 2.46x | — |
| Price / FCFMarket cap ÷ FCF | 8.64x | — | 18.06x | 20.12x |
Profitability & Efficiency
Evenly matched — REGN and ABBV each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to RPRX's 0.92x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs DBVT's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +8.5% | -130.2% | +14.3% | +62.1% |
| ROA (TTM)Return on assets | +4.3% | -89.0% | +11.1% | +3.1% |
| ROICReturn on invested capital | +6.7% | — | +8.9% | +23.9% |
| ROCEReturn on capital employed | +8.7% | -145.7% | +10.2% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 5 | 6 |
| Debt / EquityFinancial leverage | 0.92x | 0.13x | 0.09x | — |
| Net DebtTotal debt minus cash | $8.3B | -$172M | -$412M | $63.8B |
| Cash & Equiv.Liquid assets | $619M | $194M | $3.1B | $5.2B |
| Total DebtShort + long-term debt | $9.0B | $22M | $2.7B | $69.1B |
| Interest CoverageEBIT ÷ Interest expense | 3.37x | -189.82x | 108.44x | 3.28x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs REGN's -1.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +29.8% | +4.9% | -8.5% | -10.1% |
| 1-Year ReturnPast 12 months | +56.0% | +110.4% | +27.1% | +11.3% |
| 3-Year ReturnCumulative with dividends | +48.5% | +19.7% | -5.1% | +50.4% |
| 5-Year ReturnCumulative with dividends | +32.4% | -69.1% | +43.6% | +101.3% |
| 10-Year ReturnCumulative with dividends | +22.9% | -87.0% | +90.0% | +295.5% |
| CAGR (3Y)Annualised 3-year return | +14.1% | +6.2% | -1.7% | +14.6% |
Risk & Volatility
Evenly matched — RPRX and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. RPRX currently trades 97.2% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.45x | 1.26x | 0.81x | 0.34x |
| 52-Week HighHighest price in past year | $51.65 | $26.18 | $821.11 | $244.81 |
| 52-Week LowLowest price in past year | $32.15 | $7.53 | $476.49 | $176.57 |
| % of 52W HighCurrent price vs 52-week peak | +97.2% | +76.3% | +86.4% | +82.8% |
| RSI (14)Momentum oscillator 0–100 | 66.3 | 48.1 | 44.9 | 46.8 |
| Avg Volume (50D)Average daily shares traded | 3.0M | 252K | 631K | 5.8M |
Analyst Outlook
ABBV leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: RPRX as "Buy", DBVT as "Buy", REGN as "Buy", ABBV as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 7.1% for RPRX (target: $54). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $53.75 | $46.33 | $865.68 | $256.64 |
| # AnalystsCovering analysts | 11 | 15 | 48 | 41 |
| Dividend YieldAnnual dividend ÷ price | +1.3% | — | +0.5% | +3.2% |
| Dividend StreakConsecutive years of raises | 2 | 0 | 1 | 13 |
| Dividend / ShareAnnual DPS | $0.68 | — | $3.41 | $6.57 |
| Buyback YieldShare repurchases ÷ mkt cap | +5.7% | 0.0% | +5.4% | +0.3% |
ABBV leads in 2 of 6 categories (Total Returns, Analyst Outlook). RPRX leads in 1 (Income & Cash Flow). 3 tied.
RPRX vs DBVT vs REGN vs ABBV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is RPRX or DBVT or REGN or ABBV a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Royalty Pharma plc (RPRX) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — RPRX or DBVT or REGN or ABBV?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 1x versus AbbVie Inc. at 85. 5x. On forward P/E, Royalty Pharma plc is actually cheaper at 10. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Royalty Pharma plc wins at 1. 45x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — RPRX or DBVT or REGN or ABBV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — RPRX or DBVT or REGN or ABBV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 272% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 92% for Royalty Pharma plc — giving it more financial flexibility in a downturn.
05Which is growing faster — RPRX or DBVT or REGN or ABBV?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — RPRX or DBVT or REGN or ABBV?
Royalty Pharma plc (RPRX) is the more profitable company, earning 32.
4% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 32. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RPRX leads at 65. 6% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — RPRX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is RPRX or DBVT or REGN or ABBV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Royalty Pharma plc (RPRX) is the more undervalued stock at a PEG of 1. 45x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Royalty Pharma plc (RPRX) trades at 10. 3x forward P/E versus 15. 3x for Regeneron Pharmaceuticals, Inc. — 5. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — RPRX or DBVT or REGN or ABBV?
In this comparison, ABBV (3.
2% yield), RPRX (1. 3% yield), REGN (0. 5% yield) pay a dividend. DBVT does not pay a meaningful dividend and should not be held primarily for income.
09Is RPRX or DBVT or REGN or ABBV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between RPRX and DBVT and REGN and ABBV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: RPRX is a mid-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; REGN is a mid-cap deep-value stock; ABBV is a large-cap income-oriented stock. RPRX, ABBV pay a dividend while DBVT, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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