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RPRX vs DBVT vs REGN vs ABBV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
RPRX
Royalty Pharma plc

Biotechnology

HealthcareNASDAQ • US
Market Cap$21.52B
5Y Perf.+3.4%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-54.5%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$73.68B
5Y Perf.+13.7%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+106.4%

RPRX vs DBVT vs REGN vs ABBV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
RPRX logoRPRX
DBVT logoDBVT
REGN logoREGN
ABBV logoABBV
IndustryBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$21.52B$1712.35T$73.68B$358.42B
Revenue (TTM)$2.44B$0.00$14.92B$61.16B
Net Income (TTM)$828M$-168M$4.42B$4.23B
Gross Margin74.1%84.5%70.2%
Operating Margin65.1%24.3%26.7%
Forward P/E10.3x15.3x14.3x
Total Debt$8.95B$22M$2.71B$69.07B
Cash & Equiv.$619M$194M$3.12B$5.23B

RPRX vs DBVT vs REGN vs ABBVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

RPRX
DBVT
REGN
ABBV
StockJun 20May 26Return
Royalty Pharma plc (RPRX)100103.4+3.4%
DBV Technologies S.… (DBVT)10045.5-54.5%
Regeneron Pharmaceu… (REGN)100113.7+13.7%
AbbVie Inc. (ABBV)100206.4+106.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: RPRX vs DBVT vs REGN vs ABBV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV leads in 3 of 7 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Royalty Pharma plc is the stronger pick specifically for valuation and capital efficiency and profitability and margin quality. DBVT and REGN also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
RPRX
Royalty Pharma plc
The Value Pick

RPRX is the #2 pick in this set and the best alternative if valuation efficiency is your priority.

  • PEG 1.45 vs REGN's 2.43
  • Lower P/E (10.3x vs 14.3x)
  • 33.9% margin vs DBVT's 0.3%
Best for: valuation efficiency
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT is the clearest fit if your priority is momentum.

  • +110.4% vs ABBV's +11.3%
Best for: momentum
REGN
Regeneron Pharmaceuticals, Inc.
The Defensive Pick

REGN is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
  • 11.1% ROA vs DBVT's -89.0%
Best for: sleep-well-at-night
ABBV
AbbVie Inc.
The Income Pick

ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 13 yrs, beta 0.34, yield 3.2%
  • Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
  • 295.5% 10Y total return vs REGN's 90.0%
  • Beta 0.34, yield 3.2%, current ratio 0.67x
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs DBVT's -100.0%
ValueRPRX logoRPRXLower P/E (10.3x vs 14.3x)
Quality / MarginsRPRX logoRPRX33.9% margin vs DBVT's 0.3%
Stability / SafetyABBV logoABBVBeta 0.34 vs DBVT's 1.26
DividendsABBV logoABBV3.2% yield, 13-year raise streak, vs RPRX's 1.3%, (1 stock pays no dividend)
Momentum (1Y)DBVT logoDBVT+110.4% vs ABBV's +11.3%
Efficiency (ROA)REGN logoREGN11.1% ROA vs DBVT's -89.0%

RPRX vs DBVT vs REGN vs ABBV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

RPRXRoyalty Pharma plc
FY 2025
Financial Royalty Assets
95.1%$2.3B
Royalty Income, Other
4.9%$117M
DBVTDBV Technologies S.A.

Segment breakdown not available.

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B

RPRX vs DBVT vs REGN vs ABBV — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABBVLAGGINGREGN

Income & Cash Flow (Last 12 Months)

RPRX leads this category, winning 3 of 6 comparable metrics.

ABBV and DBVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. RPRX is the more profitable business, keeping 33.9% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
RevenueTrailing 12 months$2.4B$0$14.9B$61.2B
EBITDAEarnings before interest/tax$1.5B-$112M$4.2B$24.5B
Net IncomeAfter-tax profit$828M-$168M$4.4B$4.2B
Free Cash FlowCash after capex$2.6B-$151M$4.2B$18.7B
Gross MarginGross profit ÷ Revenue+74.1%+84.5%+70.2%
Operating MarginEBIT ÷ Revenue+65.1%+24.3%+26.7%
Net MarginNet income ÷ Revenue+33.9%+29.6%+6.9%
FCF MarginFCF ÷ Revenue+107.0%+27.9%+30.6%
Rev. Growth (YoY)Latest quarter vs prior year+11.0%+19.0%+10.0%
EPS Growth (YoY)Latest quarter vs prior year-100.0%+91.5%-7.2%+57.4%
RPRX leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — RPRX and DBVT and REGN each lead in 2 of 7 comparable metrics.

At 17.1x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), REGN offers better value at 2.70x vs RPRX's 3.95x — a lower PEG means you pay less per unit of expected earnings growth.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
Market CapShares × price$21.5B$1712.35T$73.7B$358.4B
Enterprise ValueMkt cap + debt − cash$29.9B$1712.35T$73.3B$422.3B
Trailing P/EPrice ÷ TTM EPS27.89x-0.76x17.09x85.50x
Forward P/EPrice ÷ next-FY EPS est.10.26x15.35x14.28x
PEG RatioP/E ÷ EPS growth rate3.95x2.70x
EV / EBITDAEnterprise value multiple19.09x17.78x14.96x
Price / SalesMarket cap ÷ Revenue9.05x5.14x5.86x
Price / BookPrice ÷ Book value/share2.89x0.66x2.46x
Price / FCFMarket cap ÷ FCF8.64x18.06x20.12x
Evenly matched — RPRX and DBVT and REGN each lead in 2 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — REGN and ABBV each lead in 4 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to RPRX's 0.92x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs DBVT's 4/9, reflecting solid financial health.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
ROE (TTM)Return on equity+8.5%-130.2%+14.3%+62.1%
ROA (TTM)Return on assets+4.3%-89.0%+11.1%+3.1%
ROICReturn on invested capital+6.7%+8.9%+23.9%
ROCEReturn on capital employed+8.7%-145.7%+10.2%+21.5%
Piotroski ScoreFundamental quality 0–94456
Debt / EquityFinancial leverage0.92x0.13x0.09x
Net DebtTotal debt minus cash$8.3B-$172M-$412M$63.8B
Cash & Equiv.Liquid assets$619M$194M$3.1B$5.2B
Total DebtShort + long-term debt$9.0B$22M$2.7B$69.1B
Interest CoverageEBIT ÷ Interest expense3.37x-189.82x108.44x3.28x
Evenly matched — REGN and ABBV each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, DBVT leads with a +110.4% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs REGN's -1.7% — a key indicator of consistent wealth creation.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
YTD ReturnYear-to-date+29.8%+4.9%-8.5%-10.1%
1-Year ReturnPast 12 months+56.0%+110.4%+27.1%+11.3%
3-Year ReturnCumulative with dividends+48.5%+19.7%-5.1%+50.4%
5-Year ReturnCumulative with dividends+32.4%-69.1%+43.6%+101.3%
10-Year ReturnCumulative with dividends+22.9%-87.0%+90.0%+295.5%
CAGR (3Y)Annualised 3-year return+14.1%+6.2%-1.7%+14.6%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — RPRX and ABBV each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. RPRX currently trades 97.2% from its 52-week high vs DBVT's 76.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
Beta (5Y)Sensitivity to S&P 5000.45x1.26x0.81x0.34x
52-Week HighHighest price in past year$51.65$26.18$821.11$244.81
52-Week LowLowest price in past year$32.15$7.53$476.49$176.57
% of 52W HighCurrent price vs 52-week peak+97.2%+76.3%+86.4%+82.8%
RSI (14)Momentum oscillator 0–10066.348.144.946.8
Avg Volume (50D)Average daily shares traded3.0M252K631K5.8M
Evenly matched — RPRX and ABBV each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: RPRX as "Buy", DBVT as "Buy", REGN as "Buy", ABBV as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 7.1% for RPRX (target: $54). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.

MetricRPRX logoRPRXRoyalty Pharma plcDBVT logoDBVTDBV Technologies …REGN logoREGNRegeneron Pharmac…ABBV logoABBVAbbVie Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$53.75$46.33$865.68$256.64
# AnalystsCovering analysts11154841
Dividend YieldAnnual dividend ÷ price+1.3%+0.5%+3.2%
Dividend StreakConsecutive years of raises20113
Dividend / ShareAnnual DPS$0.68$3.41$6.57
Buyback YieldShare repurchases ÷ mkt cap+5.7%0.0%+5.4%+0.3%
ABBV leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ABBV leads in 2 of 6 categories (Total Returns, Analyst Outlook). RPRX leads in 1 (Income & Cash Flow). 3 tied.

Best OverallAbbVie Inc. (ABBV)Leads 2 of 6 categories
Loading custom metrics...

RPRX vs DBVT vs REGN vs ABBV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is RPRX or DBVT or REGN or ABBV a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Royalty Pharma plc (RPRX) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — RPRX or DBVT or REGN or ABBV?

On trailing P/E, Regeneron Pharmaceuticals, Inc.

(REGN) is the cheapest at 17. 1x versus AbbVie Inc. at 85. 5x. On forward P/E, Royalty Pharma plc is actually cheaper at 10. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Royalty Pharma plc wins at 1. 45x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — RPRX or DBVT or REGN or ABBV?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +101. 3%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — RPRX or DBVT or REGN or ABBV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 272% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 92% for Royalty Pharma plc — giving it more financial flexibility in a downturn.

05

Which is growing faster — RPRX or DBVT or REGN or ABBV?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — RPRX or DBVT or REGN or ABBV?

Royalty Pharma plc (RPRX) is the more profitable company, earning 32.

4% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 32. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RPRX leads at 65. 6% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — RPRX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is RPRX or DBVT or REGN or ABBV more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Royalty Pharma plc (RPRX) is the more undervalued stock at a PEG of 1. 45x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Royalty Pharma plc (RPRX) trades at 10. 3x forward P/E versus 15. 3x for Regeneron Pharmaceuticals, Inc. — 5. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.

08

Which pays a better dividend — RPRX or DBVT or REGN or ABBV?

In this comparison, ABBV (3.

2% yield), RPRX (1. 3% yield), REGN (0. 5% yield) pay a dividend. DBVT does not pay a meaningful dividend and should not be held primarily for income.

09

Is RPRX or DBVT or REGN or ABBV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between RPRX and DBVT and REGN and ABBV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: RPRX is a mid-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; REGN is a mid-cap deep-value stock; ABBV is a large-cap income-oriented stock. RPRX, ABBV pay a dividend while DBVT, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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