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Stock Comparison

SANA vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SANA
Sana Biotechnology, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$918M
5Y Perf.-88.6%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-93.1%

SANA vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SANA logoSANA
EDIT logoEDIT
IndustryBiotechnologyBiotechnology
Market Cap$918M$297M
Revenue (TTM)$0.00$0.00
Net Income (TTM)$-234M$-160M
Total Debt$94M$18M
Cash & Equiv.$128M$147M

SANA vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SANA
EDIT
StockFeb 21May 26Return
Sana Biotechnology,… (SANA)10011.4-88.6%
Editas Medicine, In… (EDIT)1006.9-93.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: SANA vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SANA and EDIT are tied at the top with 2 categories each — the right choice depends on your priorities. Editas Medicine, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
SANA
Sana Biotechnology, Inc.
The Growth Leader

SANA has the current edge in this matchup, primarily because of its strength in growth and efficiency.

  • 22.6% revenue growth vs EDIT's -100.0%
  • -53.8% ROA vs EDIT's -74.2%
Best for: growth and efficiency
EDIT
Editas Medicine, Inc.
The Income Pick

EDIT is the clearest fit if your priority is income & stability and growth exposure.

  • beta 2.52
  • Rev growth -100.0%, EPS growth 37.5%
  • -90.0% 10Y total return vs SANA's -90.0%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthSANA logoSANA22.6% revenue growth vs EDIT's -100.0%
Stability / SafetyEDIT logoEDITBeta 2.52 vs SANA's 2.69
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)EDIT logoEDIT+127.8% vs SANA's +105.9%
Efficiency (ROA)SANA logoSANA-53.8% ROA vs EDIT's -74.2%

SANA vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SANASana Biotechnology, Inc.

Segment breakdown not available.

EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

SANA vs EDIT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSANALAGGINGEDIT

Income & Cash Flow (Last 12 Months)

EDIT leads this category, winning 1 of 1 comparable metric.

SANA and EDIT operate at a comparable scale, with $0 and $0 in trailing revenue.

MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$0$0
EBITDAEarnings before interest/tax-$225M$0
Net IncomeAfter-tax profit-$234M-$160M
Free Cash FlowCash after capex-$159M-$166M
Gross MarginGross profit ÷ Revenue
Operating MarginEBIT ÷ Revenue
Net MarginNet income ÷ Revenue
FCF MarginFCF ÷ Revenue
Rev. Growth (YoY)Latest quarter vs prior year-151.6%
EPS Growth (YoY)Latest quarter vs prior year+36.0%+105.5%
EDIT leads this category, winning 1 of 1 comparable metric.

Valuation Metrics

SANA leads this category, winning 2 of 2 comparable metrics.
MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
Market CapShares × price$918M$297M
Enterprise ValueMkt cap + debt − cash$885M$168M
Trailing P/EPrice ÷ TTM EPS-3.02x-1.68x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue
Price / BookPrice ÷ Book value/share3.23x9.85x
Price / FCFMarket cap ÷ FCF
SANA leads this category, winning 2 of 2 comparable metrics.

Profitability & Efficiency

SANA leads this category, winning 4 of 6 comparable metrics.

SANA delivers a -120.0% return on equity — every $100 of shareholder capital generates $-120 in annual profit, vs $-5 for EDIT. SANA carries lower financial leverage with a 0.38x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), SANA scores 2/9 vs EDIT's 1/9, reflecting mixed financial health.

MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-120.0%-5.2%
ROA (TTM)Return on assets-53.8%-74.2%
ROICReturn on invested capital-86.1%
ROCEReturn on capital employed-57.0%
Piotroski ScoreFundamental quality 0–921
Debt / EquityFinancial leverage0.38x0.66x
Net DebtTotal debt minus cash-$33M-$129M
Cash & Equiv.Liquid assets$128M$147M
Total DebtShort + long-term debt$94M$18M
Interest CoverageEBIT ÷ Interest expense
SANA leads this category, winning 4 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — SANA and EDIT each lead in 3 of 6 comparable metrics.

A $10,000 investment in SANA five years ago would be worth $1,926 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, EDIT leads with a +127.8% total return vs SANA's +105.9%. The 3-year compound annual growth rate (CAGR) favors SANA at -14.2% vs EDIT's -32.0% — a key indicator of consistent wealth creation.

MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date-16.5%+47.8%
1-Year ReturnPast 12 months+105.9%+127.8%
3-Year ReturnCumulative with dividends-36.8%-68.5%
5-Year ReturnCumulative with dividends-80.7%-91.1%
10-Year ReturnCumulative with dividends-90.0%-90.0%
CAGR (3Y)Annualised 3-year return-14.2%-32.0%
Evenly matched — SANA and EDIT each lead in 3 of 6 comparable metrics.

Risk & Volatility

EDIT leads this category, winning 2 of 2 comparable metrics.

EDIT is the less volatile stock with a 2.52 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EDIT currently trades 66.7% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5002.69x2.52x
52-Week HighHighest price in past year$6.55$4.54
52-Week LowLowest price in past year$1.60$1.29
% of 52W HighCurrent price vs 52-week peak+53.4%+66.7%
RSI (14)Momentum oscillator 0–10059.057.5
Avg Volume (50D)Average daily shares traded3.1M1.6M
EDIT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates SANA as "Buy" and EDIT as "Buy". Consensus price targets imply 147.7% upside for SANA (target: $9) vs 98.0% for EDIT (target: $6).

MetricSANA logoSANASana Biotechnolog…EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$8.67$6.00
# AnalystsCovering analysts1125
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

EDIT leads in 2 of 6 categories (Income & Cash Flow, Risk & Volatility). SANA leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.

Best OverallSana Biotechnology, Inc. (SANA)Leads 2 of 6 categories
Loading custom metrics...

SANA vs EDIT: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is SANA or EDIT a better buy right now?

Analysts rate Sana Biotechnology, Inc.

(SANA) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — SANA or EDIT?

Over the past 5 years, Sana Biotechnology, Inc.

(SANA) delivered a total return of -80. 7%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: EDIT returned -90. 0% versus SANA's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — SANA or EDIT?

By beta (market sensitivity over 5 years), Editas Medicine, Inc.

(EDIT) is the lower-risk stock at 2. 52β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately 7% more volatile than EDIT relative to the S&P 500. On balance sheet safety, Sana Biotechnology, Inc. (SANA) carries a lower debt/equity ratio of 38% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — SANA or EDIT?

On earnings-per-share growth, the picture is similar: Editas Medicine, Inc.

grew EPS 37. 5% year-over-year, compared to 20. 5% for Sana Biotechnology, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — SANA or EDIT?

Sana Biotechnology, Inc.

(SANA) is the more profitable company, earning 0. 0% net margin versus 0. 0% for Editas Medicine, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SANA leads at 0. 0% versus 0. 0% for EDIT. At the gross margin level — before operating expenses — SANA leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — SANA or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is SANA or EDIT better for a retirement portfolio?

For long-horizon retirement investors, Editas Medicine, Inc.

(EDIT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Sana Biotechnology, Inc. (SANA) carries a higher beta of 2. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (EDIT: -90. 0%, SANA: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between SANA and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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