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SCLX vs HRMY vs PAHC vs PRGO vs MCK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SCLX
Scilex Holding Company

Drug Manufacturers - General

HealthcareNASDAQ • US
Market Cap$56M
5Y Perf.-97.7%
HRMY
Harmony Biosciences Holdings, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.82B
5Y Perf.-6.2%
PAHC
Phibro Animal Health Corporation

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.75B
5Y Perf.+63.9%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.61B
5Y Perf.-71.1%
MCK
McKesson Corporation

Medical - Distribution

HealthcareNYSE • US
Market Cap$92.15B
5Y Perf.+277.6%

SCLX vs HRMY vs PAHC vs PRGO vs MCK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SCLX logoSCLX
HRMY logoHRMY
PAHC logoPAHC
PRGO logoPRGO
MCK logoMCK
IndustryDrug Manufacturers - GeneralBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericMedical - Distribution
Market Cap$56M$1.82B$1.75B$1.61B$92.15B
Revenue (TTM)$40M$899M$1.46B$4.18B$403.43B
Net Income (TTM)$-376M$146M$92M$-1.82B$4.76B
Gross Margin68.6%76.5%31.9%34.2%3.6%
Operating Margin-6.5%21.1%11.6%-4.1%1.5%
Forward P/E2.5x8.6x13.1x5.5x16.7x
Total Debt$38M$240M$762M$3.97B$7.39B
Cash & Equiv.$3M$753M$68M$532M$5.69B

SCLX vs HRMY vs PAHC vs PRGO vs MCKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SCLX
HRMY
PAHC
PRGO
MCK
StockMar 21May 26Return
Scilex Holding Comp… (SCLX)1002.3-97.7%
Harmony Biosciences… (HRMY)10093.8-6.2%
Phibro Animal Healt… (PAHC)100163.9+63.9%
Perrigo Company plc (PRGO)10028.9-71.1%
McKesson Corporation (MCK)100377.6+277.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: SCLX vs HRMY vs PAHC vs PRGO vs MCK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HRMY and PAHC are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Phibro Animal Health Corporation is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. SCLX, PRGO, and MCK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
SCLX
Scilex Holding Company
The Value Play

SCLX ranks third and is worth considering specifically for value.

  • Lower P/E (2.5x vs 5.5x)
Best for: value
HRMY
Harmony Biosciences Holdings, Inc.
The Defensive Pick

HRMY has the current edge in this matchup, primarily because of its strength in sleep-well-at-night.

  • Lower volatility, beta 0.79, Low D/E 27.5%, current ratio 3.60x
  • 16.2% margin vs SCLX's -9.3%
  • 12.0% ROA vs SCLX's -136.2%
Best for: sleep-well-at-night
PAHC
Phibro Animal Health Corporation
The Growth Play

PAHC is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 27.4%, EPS growth 18.8%, 3Y rev CAGR 11.2%
  • 27.4% revenue growth vs PRGO's -2.8%
  • +125.1% vs PRGO's -51.2%
Best for: growth exposure
PRGO
Perrigo Company plc
The Income Pick

PRGO is the clearest fit if your priority is income & stability and defensive.

  • Dividend streak 10 yrs, beta 1.18, yield 9.8%
  • Beta 1.18, yield 9.8%, current ratio 2.76x
  • 9.8% yield, 10-year raise streak, vs MCK's 0.4%, (2 stocks pay no dividend)
Best for: income & stability and defensive
MCK
McKesson Corporation
The Long-Run Compounder

MCK is the clearest fit if your priority is long-term compounding and valuation efficiency.

  • 348.1% 10Y total return vs PAHC's 128.6%
  • PEG 0.43 vs PAHC's 1.75
  • Beta 0.04 vs SCLX's 2.50
Best for: long-term compounding and valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthPAHC logoPAHC27.4% revenue growth vs PRGO's -2.8%
ValueSCLX logoSCLXLower P/E (2.5x vs 5.5x)
Quality / MarginsHRMY logoHRMY16.2% margin vs SCLX's -9.3%
Stability / SafetyMCK logoMCKBeta 0.04 vs SCLX's 2.50
DividendsPRGO logoPRGO9.8% yield, 10-year raise streak, vs MCK's 0.4%, (2 stocks pay no dividend)
Momentum (1Y)PAHC logoPAHC+125.1% vs PRGO's -51.2%
Efficiency (ROA)HRMY logoHRMY12.0% ROA vs SCLX's -136.2%

SCLX vs HRMY vs PAHC vs PRGO vs MCK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SCLXScilex Holding Company

Segment breakdown not available.

HRMYHarmony Biosciences Holdings, Inc.

Segment breakdown not available.

PAHCPhibro Animal Health Corporation
FY 2025
Vaccines
100.0%$137M
PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
MCKMcKesson Corporation
FY 2025
U.S. Pharmaceutical Segment
91.3%$327.7B
International Segment
4.1%$14.7B
Medical-Surgical Solutions Segment
3.2%$11.4B
Prescription Technology Solutions
1.5%$5.2B

SCLX vs HRMY vs PAHC vs PRGO vs MCK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHRMYLAGGINGPRGO

Income & Cash Flow (Last 12 Months)

HRMY leads this category, winning 3 of 6 comparable metrics.

MCK is the larger business by revenue, generating $403.4B annually — 9995.8x SCLX's $40M. HRMY is the more profitable business, keeping 16.2% of every revenue dollar as net income compared to SCLX's -9.3%. On growth, PAHC holds the edge at +20.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
RevenueTrailing 12 months$40M$899M$1.5B$4.2B$403.4B
EBITDAEarnings before interest/tax-$259M$209M$220M$58M$6.8B
Net IncomeAfter-tax profit-$376M$146M$92M-$1.8B$4.8B
Free Cash FlowCash after capex$24M$342M$47M$108M$6.0B
Gross MarginGross profit ÷ Revenue+68.6%+76.5%+31.9%+34.2%+3.6%
Operating MarginEBIT ÷ Revenue-6.5%+21.1%+11.6%-4.1%+1.5%
Net MarginNet income ÷ Revenue-9.3%+16.2%+6.3%-43.5%+1.2%
FCF MarginFCF ÷ Revenue+59.0%+38.0%+3.2%+2.6%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year-26.8%+16.6%+20.9%-7.2%+6.0%
EPS Growth (YoY)Latest quarter vs prior year-17.3%-29.5%+7.4%-56.4%+37.0%
HRMY leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — SCLX and PRGO and MCK each lead in 2 of 7 comparable metrics.

At 11.6x trailing earnings, HRMY trades at a 68% valuation discount to PAHC's 36.3x P/E. Adjusting for growth (PEG ratio), MCK offers better value at 0.75x vs PAHC's 4.85x — a lower PEG means you pay less per unit of expected earnings growth.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
Market CapShares × price$56M$1.8B$1.7B$1.6B$92.1B
Enterprise ValueMkt cap + debt − cash$91M$1.3B$2.4B$5.1B$93.8B
Trailing P/EPrice ÷ TTM EPS-0.41x11.59x36.27x-1.14x29.25x
Forward P/EPrice ÷ next-FY EPS est.2.51x8.62x13.10x5.53x16.66x
PEG RatioP/E ÷ EPS growth rate4.85x0.75x
EV / EBITDAEnterprise value multiple5.58x15.65x7.42x18.74x
Price / SalesMarket cap ÷ Revenue0.99x2.09x1.35x0.38x0.26x
Price / BookPrice ÷ Book value/share2.11x6.15x0.55x
Price / FCFMarket cap ÷ FCF2.89x5.23x41.82x11.12x17.63x
Evenly matched — SCLX and PRGO and MCK each lead in 2 of 7 comparable metrics.

Profitability & Efficiency

MCK leads this category, winning 5 of 9 comparable metrics.

MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $-51 for PRGO. HRMY carries lower financial leverage with a 0.28x debt-to-equity ratio, signaling a more conservative balance sheet compared to PAHC's 2.67x. On the Piotroski fundamental quality scale (0–9), SCLX scores 6/9 vs PRGO's 4/9, reflecting solid financial health.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
ROE (TTM)Return on equity+17.2%+30.8%-50.7%+3.0%
ROA (TTM)Return on assets-136.2%+12.0%+6.7%-19.8%+5.7%
ROICReturn on invested capital+42.0%+9.8%+3.7%+5.4%
ROCEReturn on capital employed+22.6%+12.0%+4.3%+30.5%
Piotroski ScoreFundamental quality 0–964546
Debt / EquityFinancial leverage0.28x2.67x1.35x
Net DebtTotal debt minus cash$35M-$513M$694M$3.4B$1.7B
Cash & Equiv.Liquid assets$3M$753M$68M$532M$5.7B
Total DebtShort + long-term debt$38M$240M$762M$4.0B$7.4B
Interest CoverageEBIT ÷ Interest expense-39.55x21.78x3.64x-7.20x33.79x
MCK leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PAHC leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $231 for SCLX. Over the past 12 months, PAHC leads with a +125.1% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors PAHC at 45.9% vs SCLX's -64.5% — a key indicator of consistent wealth creation.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
YTD ReturnYear-to-date-38.6%-15.9%+16.0%-13.5%-8.5%
1-Year ReturnPast 12 months+74.4%-6.0%+125.1%-51.2%+4.6%
3-Year ReturnCumulative with dividends-95.5%-12.8%+210.4%-58.1%+106.4%
5-Year ReturnCumulative with dividends-97.7%+13.3%+66.0%-60.1%+286.9%
10-Year ReturnCumulative with dividends-97.7%-15.1%+128.6%-77.7%+348.1%
CAGR (3Y)Annualised 3-year return-64.5%-4.5%+45.9%-25.2%+27.3%
PAHC leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — HRMY and MCK each lead in 1 of 2 comparable metrics.

MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than SCLX's 2.50 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HRMY currently trades 76.9% from its 52-week high vs SCLX's 23.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
Beta (5Y)Sensitivity to S&P 5002.30x0.81x1.35x1.21x-0.02x
52-Week HighHighest price in past year$34.27$40.87$60.08$28.44$999.00
52-Week LowLowest price in past year$3.92$25.52$19.00$9.23$637.00
% of 52W HighCurrent price vs 52-week peak+23.5%+76.9%+71.8%+41.2%+75.3%
RSI (14)Momentum oscillator 0–10059.367.660.360.916.2
Avg Volume (50D)Average daily shares traded55K791K302K3.4M757K
Evenly matched — HRMY and MCK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — PRGO and MCK each lead in 1 of 2 comparable metrics.

Analyst consensus: SCLX as "Buy", HRMY as "Buy", PAHC as "Buy", PRGO as "Hold", MCK as "Buy". Consensus price targets imply 208.9% upside for PRGO (target: $36) vs 13.5% for PAHC (target: $49). For income investors, PRGO offers the higher dividend yield at 9.81% vs MCK's 0.36%.

MetricSCLX logoSCLXScilex Holding Co…HRMY logoHRMYHarmony Bioscienc…PAHC logoPAHCPhibro Animal Hea…PRGO logoPRGOPerrigo Company p…MCK logoMCKMcKesson Corporat…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldBuy
Price TargetConsensus 12-month target$46.80$49.00$36.20$994.86
# AnalystsCovering analysts213133631
Dividend YieldAnnual dividend ÷ price+1.1%+9.8%+0.4%
Dividend StreakConsecutive years of raises01017
Dividend / ShareAnnual DPS$0.48$1.15$2.69
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+3.4%
Evenly matched — PRGO and MCK each lead in 1 of 2 comparable metrics.
Key Takeaway

HRMY leads in 1 of 6 categories (Income & Cash Flow). MCK leads in 1 (Profitability & Efficiency). 3 tied.

Best OverallHarmony Biosciences Holding… (HRMY)Leads 1 of 6 categories
Loading custom metrics...

SCLX vs HRMY vs PAHC vs PRGO vs MCK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is SCLX or HRMY or PAHC or PRGO or MCK a better buy right now?

For growth investors, Phibro Animal Health Corporation (PAHC) is the stronger pick with 27.

4% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Harmony Biosciences Holdings, Inc. (HRMY) offers the better valuation at 11. 6x trailing P/E (8. 6x forward), making it the more compelling value choice. Analysts rate Scilex Holding Company (SCLX) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — SCLX or HRMY or PAHC or PRGO or MCK?

On trailing P/E, Harmony Biosciences Holdings, Inc.

(HRMY) is the cheapest at 11. 6x versus Phibro Animal Health Corporation at 36. 3x. On forward P/E, Scilex Holding Company is actually cheaper at 2. 5x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: McKesson Corporation wins at 0. 43x versus Phibro Animal Health Corporation's 1. 75x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — SCLX or HRMY or PAHC or PRGO or MCK?

Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.

9%, compared to -97. 7% for Scilex Holding Company (SCLX). Over 10 years, the gap is even starker: MCK returned +339. 0% versus SCLX's -97. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — SCLX or HRMY or PAHC or PRGO or MCK?

By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at -0.

02β versus Scilex Holding Company's 2. 30β — meaning SCLX is approximately -14122% more volatile than MCK relative to the S&P 500. On balance sheet safety, Harmony Biosciences Holdings, Inc. (HRMY) carries a lower debt/equity ratio of 28% versus 3% for Phibro Animal Health Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — SCLX or HRMY or PAHC or PRGO or MCK?

By revenue growth (latest reported year), Phibro Animal Health Corporation (PAHC) is pulling ahead at 27.

4% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Phibro Animal Health Corporation grew EPS 1883% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HRMY leads at 25. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — SCLX or HRMY or PAHC or PRGO or MCK?

Harmony Biosciences Holdings, Inc.

(HRMY) is the more profitable company, earning 18. 3% net margin versus -128. 7% for Scilex Holding Company — meaning it keeps 18. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HRMY leads at 24. 0% versus -147. 4% for SCLX. At the gross margin level — before operating expenses — HRMY leads at 77. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is SCLX or HRMY or PAHC or PRGO or MCK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, McKesson Corporation (MCK) is the more undervalued stock at a PEG of 0. 43x versus Phibro Animal Health Corporation's 1. 75x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Scilex Holding Company (SCLX) trades at 2. 5x forward P/E versus 16. 7x for McKesson Corporation — 14. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 208. 9% to $36. 20.

08

Which pays a better dividend — SCLX or HRMY or PAHC or PRGO or MCK?

In this comparison, PRGO (9.

8% yield), PAHC (1. 1% yield), MCK (0. 4% yield) pay a dividend. SCLX, HRMY do not pay a meaningful dividend and should not be held primarily for income.

09

Is SCLX or HRMY or PAHC or PRGO or MCK better for a retirement portfolio?

For long-horizon retirement investors, McKesson Corporation (MCK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

02), +339. 0% 10Y return). Scilex Holding Company (SCLX) carries a higher beta of 2. 30 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (MCK: +339. 0%, SCLX: -97. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between SCLX and HRMY and PAHC and PRGO and MCK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: SCLX is a small-cap high-growth stock; HRMY is a small-cap high-growth stock; PAHC is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; MCK is a mid-cap high-growth stock. PAHC, PRGO pay a dividend while SCLX, HRMY, MCK do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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SCLX

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 41%
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HRMY

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 8%
  • Net Margin > 9%
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PAHC

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 10%
  • Net Margin > 5%
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PRGO

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 20%
  • Dividend Yield > 3.9%
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MCK

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Dividend Yield > 0.5%
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(SCLX: -26.8% · HRMY: 16.6%)

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