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SPRY vs DBVT vs ADMA vs HALO vs ABBV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SPRY
ARS Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$868M
5Y Perf.-81.1%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1690.08T
5Y Perf.-24.7%
ADMA
ADMA Biologics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.89B
5Y Perf.+319.0%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.55B
5Y Perf.+50.1%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$356.49B
5Y Perf.+88.1%

SPRY vs DBVT vs ADMA vs HALO vs ABBV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SPRY logoSPRY
DBVT logoDBVT
ADMA logoADMA
HALO logoHALO
ABBV logoABBV
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$868M$1690.08T$1.89B$7.55B$356.49B
Revenue (TTM)$84M$0.00$510M$1.40B$61.16B
Net Income (TTM)$-171M$-168M$165M$317M$4.23B
Gross Margin54.4%61.3%81.9%70.2%
Operating Margin-212.9%42.1%58.4%26.7%
Forward P/E9.7x8.0x14.2x
Total Debt$0.00$22M$80M$0.00$69.07B
Cash & Equiv.$41M$194M$88M$134M$5.23B

SPRY vs DBVT vs ADMA vs HALO vs ABBVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SPRY
DBVT
ADMA
HALO
ABBV
StockDec 20May 26Return
ARS Pharmaceuticals… (SPRY)10018.9-81.1%
DBV Technologies S.… (DBVT)10075.3-24.7%
ADMA Biologics, Inc. (ADMA)100419.0+319.0%
Halozyme Therapeuti… (HALO)100150.1+50.1%
AbbVie Inc. (ABBV)100188.1+88.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: SPRY vs DBVT vs ADMA vs HALO vs ABBV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ADMA and HALO are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Halozyme Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. ABBV and DBVT also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
SPRY
ARS Pharmaceuticals, Inc.
The Healthcare Pick

Among these 5 stocks, SPRY doesn't own a clear edge in any measured category.

Best for: healthcare exposure
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT is the clearest fit if your priority is momentum.

  • +100.5% vs ADMA's -61.5%
Best for: momentum
ADMA
ADMA Biologics, Inc.
The Defensive Pick

ADMA has the current edge in this matchup, primarily because of its strength in sleep-well-at-night.

  • Lower volatility, beta 1.25, Low D/E 16.7%, current ratio 6.71x
  • 32.4% margin vs SPRY's -203.3%
  • 27.4% ROA vs DBVT's -89.0%
Best for: sleep-well-at-night
HALO
Halozyme Therapeutics, Inc.
The Growth Play

HALO is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 37.6%, EPS growth -25.4%, 3Y rev CAGR 28.4%
  • 5.6% 10Y total return vs ABBV's 293.8%
  • Beta 0.51, current ratio 4.66x
  • 37.6% revenue growth vs DBVT's -100.0%
Best for: growth exposure and long-term compounding
ABBV
AbbVie Inc.
The Income Pick

ABBV ranks third and is worth considering specifically for income & stability.

  • Dividend streak 13 yrs, beta 0.28, yield 3.3%
  • Beta 0.28 vs SPRY's 1.47
  • 3.3% yield; 13-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthHALO logoHALO37.6% revenue growth vs DBVT's -100.0%
ValueHALO logoHALOLower P/E (8.0x vs 14.2x)
Quality / MarginsADMA logoADMA32.4% margin vs SPRY's -203.3%
Stability / SafetyABBV logoABBVBeta 0.28 vs SPRY's 1.47
DividendsABBV logoABBV3.3% yield; 13-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)DBVT logoDBVT+100.5% vs ADMA's -61.5%
Efficiency (ROA)ADMA logoADMA27.4% ROA vs DBVT's -89.0%

SPRY vs DBVT vs ADMA vs HALO vs ABBV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SPRYARS Pharmaceuticals, Inc.
FY 2025
Product
100.0%$72M
DBVTDBV Technologies S.A.

Segment breakdown not available.

ADMAADMA Biologics, Inc.
FY 2024
ADMA BioManufacturing Segment
97.4%$416M
Plasma Collection Centers Segment
2.6%$11M
HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B

SPRY vs DBVT vs ADMA vs HALO vs ABBV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLADMALAGGINGDBVT

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 4 of 6 comparable metrics.

ABBV and DBVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to SPRY's -2.0%. On growth, HALO holds the edge at +51.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
RevenueTrailing 12 months$84M$0$510M$1.4B$61.2B
EBITDAEarnings before interest/tax-$178M-$112M$221M$945M$24.5B
Net IncomeAfter-tax profit-$171M-$168M$165M$317M$4.2B
Free Cash FlowCash after capex-$171M-$151M$108M$645M$18.7B
Gross MarginGross profit ÷ Revenue+54.4%+61.3%+81.9%+70.2%
Operating MarginEBIT ÷ Revenue-2.1%+42.1%+58.4%+26.7%
Net MarginNet income ÷ Revenue-2.0%+32.4%+22.7%+6.9%
FCF MarginFCF ÷ Revenue-2.0%+21.2%+46.2%+30.6%
Rev. Growth (YoY)Latest quarter vs prior year-67.6%-0.3%+51.6%+10.0%
EPS Growth (YoY)Latest quarter vs prior year-180.4%+91.5%+72.7%-2.1%+57.4%
HALO leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

HALO leads this category, winning 3 of 6 comparable metrics.

At 13.6x trailing earnings, ADMA trades at a 84% valuation discount to ABBV's 85.0x P/E. On an enterprise value basis, HALO's 8.2x EV/EBITDA is more attractive than ABBV's 14.9x.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
Market CapShares × price$868M$1690.08T$1.9B$7.6B$356.5B
Enterprise ValueMkt cap + debt − cash$826M$1690.08T$1.9B$7.4B$420.3B
Trailing P/EPrice ÷ TTM EPS-5.02x-0.75x13.62x25.05x85.04x
Forward P/EPrice ÷ next-FY EPS est.9.69x7.96x14.17x
PEG RatioP/E ÷ EPS growth rate1.09x
EV / EBITDAEnterprise value multiple9.45x8.20x14.89x
Price / SalesMarket cap ÷ Revenue10.30x3.71x5.41x5.83x
Price / BookPrice ÷ Book value/share7.54x0.65x4.19x162.76x
Price / FCFMarket cap ÷ FCF68.06x11.72x20.01x
HALO leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

ADMA leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADMA's 0.17x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs SPRY's 3/9, reflecting solid financial health.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
ROE (TTM)Return on equity-100.3%-130.2%+39.0%+6.5%+62.1%
ROA (TTM)Return on assets-51.1%-89.0%+27.4%+12.5%+3.1%
ROICReturn on invested capital-96.5%+36.0%+73.4%+23.9%
ROCEReturn on capital employed-58.2%-145.7%+38.8%+38.2%+21.5%
Piotroski ScoreFundamental quality 0–934556
Debt / EquityFinancial leverage0.13x0.17x
Net DebtTotal debt minus cash-$41M-$172M-$8M-$134M$63.8B
Cash & Equiv.Liquid assets$41M$194M$88M$134M$5.2B
Total DebtShort + long-term debt$0$22M$80M$0$69.1B
Interest CoverageEBIT ÷ Interest expense-189.82x50.85x46.08x3.28x
ADMA leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ADMA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ADMA five years ago would be worth $48,922 today (with dividends reinvested), compared to $3,172 for DBVT. Over the past 12 months, DBVT leads with a +100.5% total return vs ADMA's -61.5%. The 3-year compound annual growth rate (CAGR) favors ADMA at 32.7% vs DBVT's 5.7% — a key indicator of consistent wealth creation.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
YTD ReturnYear-to-date-23.9%+3.6%-54.3%-8.8%-10.6%
1-Year ReturnPast 12 months-35.2%+100.5%-61.5%-5.3%+12.2%
3-Year ReturnCumulative with dividends+45.4%+18.1%+133.4%+111.8%+49.7%
5-Year ReturnCumulative with dividends-67.0%-68.3%+389.2%+39.1%+99.6%
10-Year ReturnCumulative with dividends-65.0%-87.1%+34.8%+559.7%+293.8%
CAGR (3Y)Annualised 3-year return+13.3%+5.7%+32.7%+28.4%+14.4%
ADMA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

ABBV leads this category, winning 2 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.28 beta — it tends to amplify market swings less than SPRY's 1.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABBV currently trades 82.3% from its 52-week high vs ADMA's 35.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
Beta (5Y)Sensitivity to S&P 5001.47x1.26x1.25x0.51x0.28x
52-Week HighHighest price in past year$18.90$26.18$22.73$82.22$244.81
52-Week LowLowest price in past year$6.66$7.53$7.21$47.50$176.57
% of 52W HighCurrent price vs 52-week peak+46.2%+75.3%+35.9%+78.0%+82.3%
RSI (14)Momentum oscillator 0–10059.947.426.047.743.9
Avg Volume (50D)Average daily shares traded1.6M252K7.4M1.4M5.8M
ABBV leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: SPRY as "Hold", DBVT as "Buy", ADMA as "Buy", HALO as "Buy", ABBV as "Buy". Consensus price targets imply 191.8% upside for SPRY (target: $26) vs 17.9% for HALO (target: $76). ABBV is the only dividend payer here at 3.26% yield — a key consideration for income-focused portfolios.

MetricSPRY logoSPRYARS Pharmaceutica…DBVT logoDBVTDBV Technologies …ADMA logoADMAADMA Biologics, I…HALO logoHALOHalozyme Therapeu…ABBV logoABBVAbbVie Inc.
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuyBuy
Price TargetConsensus 12-month target$25.50$46.33$21.00$75.60$256.69
# AnalystsCovering analysts1015102741
Dividend YieldAnnual dividend ÷ price+3.3%
Dividend StreakConsecutive years of raises0113
Dividend / ShareAnnual DPS$6.57
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+1.7%+4.5%+0.3%
ABBV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

HALO leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). ADMA leads in 2 (Profitability & Efficiency, Total Returns).

Best OverallADMA Biologics, Inc. (ADMA)Leads 2 of 6 categories
Loading custom metrics...

SPRY vs DBVT vs ADMA vs HALO vs ABBV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is SPRY or DBVT or ADMA or HALO or ABBV a better buy right now?

For growth investors, Halozyme Therapeutics, Inc.

(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus -5. 5% for ARS Pharmaceuticals, Inc. (SPRY). ADMA Biologics, Inc. (ADMA) offers the better valuation at 13. 6x trailing P/E (9. 7x forward), making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — SPRY or DBVT or ADMA or HALO or ABBV?

On trailing P/E, ADMA Biologics, Inc.

(ADMA) is the cheapest at 13. 6x versus AbbVie Inc. at 85. 0x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — SPRY or DBVT or ADMA or HALO or ABBV?

Over the past 5 years, ADMA Biologics, Inc.

(ADMA) delivered a total return of +389. 2%, compared to -68. 3% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: HALO returned +559. 7% versus DBVT's -87. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — SPRY or DBVT or ADMA or HALO or ABBV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 28β versus ARS Pharmaceuticals, Inc. 's 1. 47β — meaning SPRY is approximately 433% more volatile than ABBV relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 17% for ADMA Biologics, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — SPRY or DBVT or ADMA or HALO or ABBV?

By revenue growth (latest reported year), Halozyme Therapeutics, Inc.

(HALO) is pulling ahead at 37. 6% versus -5. 5% for ARS Pharmaceuticals, Inc. (SPRY). On earnings-per-share growth, the picture is similar: AbbVie Inc. grew EPS -0. 8% year-over-year, compared to -23. 3% for ARS Pharmaceuticals, Inc.. Over a 3-year CAGR, SPRY leads at 300. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — SPRY or DBVT or ADMA or HALO or ABBV?

ADMA Biologics, Inc.

(ADMA) is the more profitable company, earning 28. 8% net margin versus -203. 3% for ARS Pharmaceuticals, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -212. 9% for SPRY. At the gross margin level — before operating expenses — HALO leads at 78. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is SPRY or DBVT or ADMA or HALO or ABBV more undervalued right now?

On forward earnings alone, Halozyme Therapeutics, Inc.

(HALO) trades at 8. 0x forward P/E versus 14. 2x for AbbVie Inc. — 6. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for SPRY: 191. 8% to $25. 50.

08

Which pays a better dividend — SPRY or DBVT or ADMA or HALO or ABBV?

In this comparison, ABBV (3.

3% yield) pays a dividend. SPRY, DBVT, ADMA, HALO do not pay a meaningful dividend and should not be held primarily for income.

09

Is SPRY or DBVT or ADMA or HALO or ABBV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 28), 3. 3% yield, +293. 8% 10Y return). Both have compounded well over 10 years (ABBV: +293. 8%, SPRY: -65. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between SPRY and DBVT and ADMA and HALO and ABBV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: SPRY is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; ADMA is a small-cap high-growth stock; HALO is a small-cap high-growth stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while SPRY, DBVT, ADMA, HALO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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