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Stock Comparison

SPRY vs HALO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SPRY
ARS Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$894M
5Y Perf.-81.1%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.68B
5Y Perf.+50.1%

SPRY vs HALO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SPRY logoSPRY
HALO logoHALO
IndustryBiotechnologyBiotechnology
Market Cap$894M$7.68B
Revenue (TTM)$84M$1.40B
Net Income (TTM)$-171M$317M
Gross Margin54.4%81.9%
Operating Margin-212.9%58.4%
Forward P/E8.0x
Total Debt$0.00$0.00
Cash & Equiv.$41M$134M

SPRY vs HALOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SPRY
HALO
StockDec 20May 26Return
ARS Pharmaceuticals… (SPRY)10018.9-81.1%
Halozyme Therapeuti… (HALO)100150.1+50.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: SPRY vs HALO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HALO leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
SPRY
ARS Pharmaceuticals, Inc.
The Specific-Use Pick

In this particular matchup, SPRY is outpaced on most metrics by others in the set.

Best for: healthcare exposure
HALO
Halozyme Therapeutics, Inc.
The Income Pick

HALO carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.56
  • Rev growth 37.6%, EPS growth -25.4%, 3Y rev CAGR 28.4%
  • 5.7% 10Y total return vs SPRY's -64.0%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthHALO logoHALO37.6% revenue growth vs SPRY's -5.5%
Quality / MarginsHALO logoHALO22.7% margin vs SPRY's -203.3%
Stability / SafetyHALO logoHALOBeta 0.56 vs SPRY's 1.47
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)HALO logoHALO-7.1% vs SPRY's -33.3%
Efficiency (ROA)HALO logoHALO12.5% ROA vs SPRY's -51.1%, ROIC 73.4% vs -96.5%

SPRY vs HALO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SPRYARS Pharmaceuticals, Inc.
FY 2025
Product
100.0%$72M
HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M

SPRY vs HALO — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGSPRY

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 5 of 6 comparable metrics.

HALO is the larger business by revenue, generating $1.4B annually — 16.6x SPRY's $84M. HALO is the more profitable business, keeping 22.7% of every revenue dollar as net income compared to SPRY's -2.0%. On growth, HALO holds the edge at +51.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
RevenueTrailing 12 months$84M$1.4B
EBITDAEarnings before interest/tax-$178M$945M
Net IncomeAfter-tax profit-$171M$317M
Free Cash FlowCash after capex-$171M$645M
Gross MarginGross profit ÷ Revenue+54.4%+81.9%
Operating MarginEBIT ÷ Revenue-2.1%+58.4%
Net MarginNet income ÷ Revenue-2.0%+22.7%
FCF MarginFCF ÷ Revenue-2.0%+46.2%
Rev. Growth (YoY)Latest quarter vs prior year-67.6%+51.6%
EPS Growth (YoY)Latest quarter vs prior year-180.4%-2.1%
HALO leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

SPRY leads this category, winning 2 of 3 comparable metrics.
MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
Market CapShares × price$894M$7.7B
Enterprise ValueMkt cap + debt − cash$852M$7.5B
Trailing P/EPrice ÷ TTM EPS-5.17x25.46x
Forward P/EPrice ÷ next-FY EPS est.7.96x
PEG RatioP/E ÷ EPS growth rate1.11x
EV / EBITDAEnterprise value multiple8.34x
Price / SalesMarket cap ÷ Revenue10.60x5.50x
Price / BookPrice ÷ Book value/share7.76x165.47x
Price / FCFMarket cap ÷ FCF11.91x
SPRY leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

HALO leads this category, winning 6 of 6 comparable metrics.

HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-100 for SPRY. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs SPRY's 3/9, reflecting solid financial health.

MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
ROE (TTM)Return on equity-100.3%+6.5%
ROA (TTM)Return on assets-51.1%+12.5%
ROICReturn on invested capital-96.5%+73.4%
ROCEReturn on capital employed-58.2%+38.2%
Piotroski ScoreFundamental quality 0–935
Debt / EquityFinancial leverage
Net DebtTotal debt minus cash-$41M-$134M
Cash & Equiv.Liquid assets$41M$134M
Total DebtShort + long-term debt$0$0
Interest CoverageEBIT ÷ Interest expense46.08x
HALO leads this category, winning 6 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

HALO leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in HALO five years ago would be worth $13,704 today (with dividends reinvested), compared to $3,196 for SPRY. Over the past 12 months, HALO leads with a -7.1% total return vs SPRY's -33.3%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs SPRY's 14.4% — a key indicator of consistent wealth creation.

MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
YTD ReturnYear-to-date-21.7%-7.3%
1-Year ReturnPast 12 months-33.3%-7.1%
3-Year ReturnCumulative with dividends+49.8%+115.3%
5-Year ReturnCumulative with dividends-68.0%+37.0%
10-Year ReturnCumulative with dividends-64.0%+570.7%
CAGR (3Y)Annualised 3-year return+14.4%+29.1%
HALO leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

HALO leads this category, winning 2 of 2 comparable metrics.

HALO is the less volatile stock with a 0.56 beta — it tends to amplify market swings less than SPRY's 1.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HALO currently trades 79.3% from its 52-week high vs SPRY's 47.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
Beta (5Y)Sensitivity to S&P 5001.47x0.51x
52-Week HighHighest price in past year$18.90$82.22
52-Week LowLowest price in past year$6.66$47.50
% of 52W HighCurrent price vs 52-week peak+47.6%+79.3%
RSI (14)Momentum oscillator 0–10066.152.4
Avg Volume (50D)Average daily shares traded1.5M1.4M
HALO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates SPRY as "Hold" and HALO as "Buy". Consensus price targets imply 183.3% upside for SPRY (target: $26) vs 16.0% for HALO (target: $76).

MetricSPRY logoSPRYARS Pharmaceutica…HALO logoHALOHalozyme Therapeu…
Analyst RatingConsensus buy/hold/sellHoldBuy
Price TargetConsensus 12-month target$25.50$75.60
# AnalystsCovering analysts1027
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+4.5%
Insufficient data to determine a leader in this category.
Key Takeaway

HALO leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). SPRY leads in 1 (Valuation Metrics).

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 4 of 6 categories
Loading custom metrics...

SPRY vs HALO: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is SPRY or HALO a better buy right now?

For growth investors, Halozyme Therapeutics, Inc.

(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus -5. 5% for ARS Pharmaceuticals, Inc. (SPRY). Halozyme Therapeutics, Inc. (HALO) offers the better valuation at 25. 5x trailing P/E (8. 0x forward), making it the more compelling value choice. Analysts rate Halozyme Therapeutics, Inc. (HALO) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — SPRY or HALO?

Over the past 5 years, Halozyme Therapeutics, Inc.

(HALO) delivered a total return of +37. 0%, compared to -68. 0% for ARS Pharmaceuticals, Inc. (SPRY). Over 10 years, the gap is even starker: HALO returned +559. 7% versus SPRY's -65. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — SPRY or HALO?

By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.

(HALO) is the lower-risk stock at 0. 51β versus ARS Pharmaceuticals, Inc. 's 1. 47β — meaning SPRY is approximately 187% more volatile than HALO relative to the S&P 500.

04

Which is growing faster — SPRY or HALO?

By revenue growth (latest reported year), Halozyme Therapeutics, Inc.

(HALO) is pulling ahead at 37. 6% versus -5. 5% for ARS Pharmaceuticals, Inc. (SPRY). On earnings-per-share growth, the picture is similar: Halozyme Therapeutics, Inc. grew EPS -25. 4% year-over-year, compared to -23. 3% for ARS Pharmaceuticals, Inc.. Over a 3-year CAGR, SPRY leads at 300. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — SPRY or HALO?

Halozyme Therapeutics, Inc.

(HALO) is the more profitable company, earning 22. 7% net margin versus -203. 3% for ARS Pharmaceuticals, Inc. — meaning it keeps 22. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -212. 9% for SPRY. At the gross margin level — before operating expenses — HALO leads at 78. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is SPRY or HALO more undervalued right now?

Analyst consensus price targets imply the most upside for SPRY: 183.

3% to $25. 50.

07

Which pays a better dividend — SPRY or HALO?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is SPRY or HALO better for a retirement portfolio?

For long-horizon retirement investors, Halozyme Therapeutics, Inc.

(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 51), +559. 7% 10Y return). Both have compounded well over 10 years (HALO: +559. 7%, SPRY: -65. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between SPRY and HALO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: SPRY is a small-cap quality compounder stock; HALO is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Stocks Like

SPRY

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 32%
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HALO

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 25%
  • Net Margin > 13%
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Revenue Growth>
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(SPRY: -67.6% · HALO: 51.6%)

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