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Stock Comparison

STE vs CNMD vs HOLX vs MMSI

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
STE
STERIS plc

Medical - Devices

HealthcareNYSE • IE
Market Cap$21.00B
5Y Perf.+28.8%
CNMD
CONMED Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$1.17B
5Y Perf.-48.1%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
MMSI
Merit Medical Systems, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$3.72B
5Y Perf.+38.5%

STE vs CNMD vs HOLX vs MMSI — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
STE logoSTE
CNMD logoCNMD
HOLX logoHOLX
MMSI logoMMSI
IndustryMedical - DevicesMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$21.00B$1.17B$16.97B$3.72B
Revenue (TTM)$5.83B$1.37B$4.13B$1.54B
Net Income (TTM)$708M$55M$544M$139M
Gross Margin44.1%53.6%52.8%48.7%
Operating Margin17.2%11.3%17.5%12.2%
Forward P/E21.0x8.7x17.2x15.5x
Total Debt$2.20B$835M$2.63B$898M
Cash & Equiv.$172M$41M$1.96B$449M

STE vs CNMD vs HOLX vs MMSILong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

STE
CNMD
HOLX
MMSI
StockMay 20May 26Return
STERIS plc (STE)100128.8+28.8%
CONMED Corporation (CNMD)10051.9-48.1%
Hologic, Inc. (HOLX)100142.6+42.6%
Merit Medical Syste… (MMSI)100138.5+38.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: STE vs CNMD vs HOLX vs MMSI

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HOLX leads in 3 of 7 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. STERIS plc is the stronger pick specifically for dividend income and shareholder returns and operational efficiency and capital deployment. CNMD and MMSI also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
STE
STERIS plc
The Income Pick

STE is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.

  • Dividend streak 14 yrs, beta 0.69, yield 1.0%
  • 220.0% 10Y total return vs HOLX's 124.3%
  • 1.0% yield, 14-year raise streak, vs CNMD's 2.1%, (2 stocks pay no dividend)
  • 6.7% ROA vs CNMD's 2.4%, ROIC 7.2% vs 5.8%
Best for: income & stability and long-term compounding
CNMD
CONMED Corporation
The Value Pick

CNMD is the clearest fit if your priority is valuation efficiency.

  • PEG 0.24 vs STE's 3.86
  • Lower P/E (8.7x vs 15.5x)
Best for: valuation efficiency
HOLX
Hologic, Inc.
The Defensive Pick

HOLX carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
  • Beta 0.41, current ratio 3.75x
  • 13.2% margin vs CNMD's 4.0%
  • Beta 0.41 vs CNMD's 1.34, lower leverage
Best for: sleep-well-at-night and defensive
MMSI
Merit Medical Systems, Inc.
The Growth Play

MMSI is the clearest fit if your priority is growth exposure.

  • Rev growth 11.7%, EPS growth 4.9%, 3Y rev CAGR 9.6%
  • 11.7% revenue growth vs HOLX's 1.7%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthMMSI logoMMSI11.7% revenue growth vs HOLX's 1.7%
ValueCNMD logoCNMDLower P/E (8.7x vs 15.5x)
Quality / MarginsHOLX logoHOLX13.2% margin vs CNMD's 4.0%
Stability / SafetyHOLX logoHOLXBeta 0.41 vs CNMD's 1.34, lower leverage
DividendsSTE logoSTE1.0% yield, 14-year raise streak, vs CNMD's 2.1%, (2 stocks pay no dividend)
Momentum (1Y)HOLX logoHOLX+37.1% vs MMSI's -33.8%
Efficiency (ROA)STE logoSTE6.7% ROA vs CNMD's 2.4%, ROIC 7.2% vs 5.8%

STE vs CNMD vs HOLX vs MMSI — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

STESTERIS plc
FY 2025
Product
52.6%$2.9B
Service
47.4%$2.6B
CNMDCONMED Corporation
FY 2025
General Surgery
58.2%$800M
Orthopedic Surgery
41.8%$575M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
MMSIMerit Medical Systems, Inc.
FY 2025
Cardiovascular
95.2%$1.4B
Endoscopy
4.8%$73M

STE vs CNMD vs HOLX vs MMSI — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHOLXLAGGINGMMSI

Income & Cash Flow (Last 12 Months)

HOLX leads this category, winning 3 of 6 comparable metrics.

STE is the larger business by revenue, generating $5.8B annually — 4.2x CNMD's $1.4B. HOLX is the more profitable business, keeping 13.2% of every revenue dollar as net income compared to CNMD's 4.0%. On growth, STE holds the edge at +9.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
RevenueTrailing 12 months$5.8B$1.4B$4.1B$1.5B
EBITDAEarnings before interest/tax$1.4B$219M$974M$290M
Net IncomeAfter-tax profit$708M$55M$544M$139M
Free Cash FlowCash after capex$917M$124M$1000M$274M
Gross MarginGross profit ÷ Revenue+44.1%+53.6%+52.8%+48.7%
Operating MarginEBIT ÷ Revenue+17.2%+11.3%+17.5%+12.2%
Net MarginNet income ÷ Revenue+12.1%+4.0%+13.2%+9.0%
FCF MarginFCF ÷ Revenue+15.7%+9.0%+24.2%+17.8%
Rev. Growth (YoY)Latest quarter vs prior year+9.2%-0.7%+2.5%+7.8%
EPS Growth (YoY)Latest quarter vs prior year+12.0%+136.8%-9.2%+38.8%
HOLX leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

CNMD leads this category, winning 7 of 7 comparable metrics.

At 25.2x trailing earnings, CNMD trades at a 27% valuation discount to STE's 34.5x P/E. Adjusting for growth (PEG ratio), CNMD offers better value at 0.69x vs STE's 6.35x — a lower PEG means you pay less per unit of expected earnings growth.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
Market CapShares × price$21.0B$1.2B$17.0B$3.7B
Enterprise ValueMkt cap + debt − cash$23.0B$2.0B$17.6B$4.2B
Trailing P/EPrice ÷ TTM EPS34.46x25.22x30.53x29.26x
Forward P/EPrice ÷ next-FY EPS est.20.95x8.71x17.21x15.46x
PEG RatioP/E ÷ EPS growth rate6.35x0.69x
EV / EBITDAEnterprise value multiple17.15x10.17x17.39x13.06x
Price / SalesMarket cap ÷ Revenue3.85x0.85x4.14x2.45x
Price / BookPrice ÷ Book value/share3.20x1.15x3.43x2.38x
Price / FCFMarket cap ÷ FCF27.00x7.78x18.44x17.24x
CNMD leads this category, winning 7 of 7 comparable metrics.

Profitability & Efficiency

STE leads this category, winning 5 of 9 comparable metrics.

HOLX delivers a 11.0% return on equity — every $100 of shareholder capital generates $11 in annual profit, vs $5 for CNMD. STE carries lower financial leverage with a 0.33x debt-to-equity ratio, signaling a more conservative balance sheet compared to CNMD's 0.81x. On the Piotroski fundamental quality scale (0–9), STE scores 8/9 vs CNMD's 5/9, reflecting strong financial health.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
ROE (TTM)Return on equity+9.9%+5.4%+11.0%+8.9%
ROA (TTM)Return on assets+6.7%+2.4%+6.1%+5.2%
ROICReturn on invested capital+7.2%+5.8%+9.4%+7.2%
ROCEReturn on capital employed+9.0%+7.0%+8.8%+7.9%
Piotroski ScoreFundamental quality 0–98576
Debt / EquityFinancial leverage0.33x0.81x0.52x0.57x
Net DebtTotal debt minus cash$2.0B$794M$667M$450M
Cash & Equiv.Liquid assets$172M$41M$2.0B$449M
Total DebtShort + long-term debt$2.2B$835M$2.6B$898M
Interest CoverageEBIT ÷ Interest expense15.94x5.20x8.00x10.74x
STE leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — STE and HOLX each lead in 3 of 6 comparable metrics.

A $10,000 investment in HOLX five years ago would be worth $11,582 today (with dividends reinvested), compared to $2,902 for CNMD. Over the past 12 months, HOLX leads with a +37.1% total return vs MMSI's -33.8%. The 3-year compound annual growth rate (CAGR) favors STE at 5.3% vs CNMD's -31.1% — a key indicator of consistent wealth creation.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
YTD ReturnYear-to-date-14.3%-6.0%+1.9%-27.9%
1-Year ReturnPast 12 months-3.9%-31.3%+37.1%-33.8%
3-Year ReturnCumulative with dividends+16.6%-67.3%-8.5%-26.5%
5-Year ReturnCumulative with dividends+5.9%-71.0%+15.8%-3.6%
10-Year ReturnCumulative with dividends+220.0%+6.6%+124.3%+214.6%
CAGR (3Y)Annualised 3-year return+5.3%-31.1%-2.9%-9.8%
Evenly matched — STE and HOLX each lead in 3 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than CNMD's 1.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs MMSI's 62.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
Beta (5Y)Sensitivity to S&P 5000.69x1.34x0.41x0.71x
52-Week HighHighest price in past year$269.44$61.08$76.04$100.19
52-Week LowLowest price in past year$204.81$33.21$52.81$59.74
% of 52W HighCurrent price vs 52-week peak+79.3%+62.4%+100.0%+62.2%
RSI (14)Momentum oscillator 0–10041.249.669.134.9
Avg Volume (50D)Average daily shares traded710K406K10.0M769K
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — STE and CNMD each lead in 1 of 2 comparable metrics.

Analyst consensus: STE as "Buy", CNMD as "Hold", HOLX as "Hold", MMSI as "Buy". Consensus price targets imply 104.8% upside for CNMD (target: $78) vs 3.9% for HOLX (target: $79). For income investors, CNMD offers the higher dividend yield at 2.09% vs STE's 1.04%.

MetricSTE logoSTESTERIS plcCNMD logoCNMDCONMED CorporationHOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…
Analyst RatingConsensus buy/hold/sellBuyHoldHoldBuy
Price TargetConsensus 12-month target$256.67$78.00$79.00$95.00
# AnalystsCovering analysts13214213
Dividend YieldAnnual dividend ÷ price+1.0%+2.1%
Dividend StreakConsecutive years of raises142
Dividend / ShareAnnual DPS$2.22$0.79
Buyback YieldShare repurchases ÷ mkt cap+1.0%0.0%+4.4%0.0%
Evenly matched — STE and CNMD each lead in 1 of 2 comparable metrics.
Key Takeaway

HOLX leads in 2 of 6 categories (Income & Cash Flow, Risk & Volatility). CNMD leads in 1 (Valuation Metrics). 2 tied.

Best OverallHologic, Inc. (HOLX)Leads 2 of 6 categories
Loading custom metrics...

STE vs CNMD vs HOLX vs MMSI: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is STE or CNMD or HOLX or MMSI a better buy right now?

For growth investors, Merit Medical Systems, Inc.

(MMSI) is the stronger pick with 11. 7% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). CONMED Corporation (CNMD) offers the better valuation at 25. 2x trailing P/E (8. 7x forward), making it the more compelling value choice. Analysts rate STERIS plc (STE) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — STE or CNMD or HOLX or MMSI?

On trailing P/E, CONMED Corporation (CNMD) is the cheapest at 25.

2x versus STERIS plc at 34. 5x. On forward P/E, CONMED Corporation is actually cheaper at 8. 7x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: CONMED Corporation wins at 0. 24x versus STERIS plc's 3. 86x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — STE or CNMD or HOLX or MMSI?

Over the past 5 years, Hologic, Inc.

(HOLX) delivered a total return of +15. 8%, compared to -71. 0% for CONMED Corporation (CNMD). Over 10 years, the gap is even starker: STE returned +220. 0% versus CNMD's +6. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — STE or CNMD or HOLX or MMSI?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 41β versus CONMED Corporation's 1. 34β — meaning CNMD is approximately 225% more volatile than HOLX relative to the S&P 500. On balance sheet safety, STERIS plc (STE) carries a lower debt/equity ratio of 33% versus 81% for CONMED Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — STE or CNMD or HOLX or MMSI?

By revenue growth (latest reported year), Merit Medical Systems, Inc.

(MMSI) is pulling ahead at 11. 7% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: STERIS plc grew EPS 62. 7% year-over-year, compared to -64. 6% for CONMED Corporation. Over a 3-year CAGR, MMSI leads at 9. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — STE or CNMD or HOLX or MMSI?

Hologic, Inc.

(HOLX) is the more profitable company, earning 13. 8% net margin versus 3. 4% for CONMED Corporation — meaning it keeps 13. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus 10. 3% for CNMD. At the gross margin level — before operating expenses — HOLX leads at 61. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is STE or CNMD or HOLX or MMSI more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, CONMED Corporation (CNMD) is the more undervalued stock at a PEG of 0. 24x versus STERIS plc's 3. 86x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, CONMED Corporation (CNMD) trades at 8. 7x forward P/E versus 21. 0x for STERIS plc — 12. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CNMD: 104. 8% to $78. 00.

08

Which pays a better dividend — STE or CNMD or HOLX or MMSI?

In this comparison, CNMD (2.

1% yield), STE (1. 0% yield) pay a dividend. HOLX, MMSI do not pay a meaningful dividend and should not be held primarily for income.

09

Is STE or CNMD or HOLX or MMSI better for a retirement portfolio?

For long-horizon retirement investors, STERIS plc (STE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

69), 1. 0% yield, +220. 0% 10Y return). Both have compounded well over 10 years (STE: +220. 0%, CNMD: +6. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between STE and CNMD and HOLX and MMSI?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

STE, CNMD pay a dividend while HOLX, MMSI do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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STE

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 32%
  • Dividend Yield > 0.8%
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HOLX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 7%
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MMSI

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 5%
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Custom Screen

Beat Both

Find stocks that outperform STE and CNMD and HOLX and MMSI on the metrics below

Revenue Growth>
%
(STE: 9.2% · CNMD: -0.7%)
Net Margin>
%
(STE: 12.1% · CNMD: 4.0%)
P/E Ratio<
x
(STE: 34.5x · CNMD: 25.2x)

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