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Stock Comparison

TBPH vs PRGO vs JNJ vs HLN vs MCK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TBPH
Theravance Biopharma, Inc.

Biotechnology

HealthcareNASDAQ • KY
Market Cap$862M
5Y Perf.+93.6%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.61B
5Y Perf.-72.0%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$536.23B
5Y Perf.+27.5%
HLN
Haleon plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • GB
Market Cap$41.45B
5Y Perf.+32.4%
MCK
McKesson Corporation

Medical - Distribution

HealthcareNYSE • US
Market Cap$92.15B
5Y Perf.+120.2%

TBPH vs PRGO vs JNJ vs HLN vs MCK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TBPH logoTBPH
PRGO logoPRGO
JNJ logoJNJ
HLN logoHLN
MCK logoMCK
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralDrug Manufacturers - Specialty & GenericMedical - Distribution
Market Cap$862M$1.61B$536.23B$41.45B$92.15B
Revenue (TTM)$80M$4.18B$92.15B$22.01B$403.43B
Net Income (TTM)$29M$-1.82B$25.12B$3.18B$4.76B
Gross Margin62.6%34.2%68.1%63.9%3.6%
Operating Margin-40.9%-4.1%26.1%21.4%1.5%
Forward P/E6.7x5.6x19.2x22.2x19.3x
Total Debt$50M$3.97B$36.63B$8.59B$7.39B
Cash & Equiv.$38M$532M$24.11B$1.32B$5.69B

TBPH vs PRGO vs JNJ vs HLN vs MCKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TBPH
PRGO
JNJ
HLN
MCK
StockJul 22May 26Return
Theravance Biopharm… (TBPH)100193.6+93.6%
Perrigo Company plc (PRGO)10028.0-72.0%
Johnson & Johnson (JNJ)100127.5+27.5%
Haleon plc (HLN)100132.4+32.4%
McKesson Corporation (MCK)100220.2+120.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: TBPH vs PRGO vs JNJ vs HLN vs MCK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TBPH and PRGO are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Perrigo Company plc is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. MCK and JNJ also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TBPH
Theravance Biopharma, Inc.
The Quality Compounder

TBPH has the current edge in this matchup, primarily because of its strength in quality and momentum.

  • 36.5% margin vs PRGO's -43.5%
  • +70.4% vs PRGO's -51.2%
Best for: quality and momentum
PRGO
Perrigo Company plc
The Value Play

PRGO is the #2 pick in this set and the best alternative if value and dividends is your priority.

  • Lower P/E (5.6x vs 22.2x)
  • 9.8% yield, 10-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Best for: value and dividends
JNJ
Johnson & Johnson
The Income Pick

JNJ is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • Dividend streak 36 yrs, beta 0.06, yield 2.2%
  • Lower volatility, beta 0.06, Low D/E 51.2%, current ratio 1.11x
  • Beta 0.06, yield 2.2%, current ratio 1.11x
  • 13.0% ROA vs PRGO's -19.8%, ROIC 20.7% vs 3.7%
Best for: income & stability and sleep-well-at-night
HLN
Haleon plc
The Lower-Volatility Pick

Among these 5 stocks, HLN doesn't own a clear edge in any measured category.

Best for: healthcare exposure
MCK
McKesson Corporation
The Growth Play

MCK ranks third and is worth considering specifically for growth exposure and long-term compounding.

  • Rev growth 16.2%, EPS growth 14.9%, 3Y rev CAGR 10.8%
  • 348.1% 10Y total return vs JNJ's 132.3%
  • PEG 0.49 vs JNJ's 34.17
  • 16.2% revenue growth vs HLN's -4.0%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthMCK logoMCK16.2% revenue growth vs HLN's -4.0%
ValuePRGO logoPRGOLower P/E (5.6x vs 22.2x)
Quality / MarginsTBPH logoTBPH36.5% margin vs PRGO's -43.5%
Stability / SafetyMCK logoMCKBeta 0.04 vs PRGO's 1.18
DividendsPRGO logoPRGO9.8% yield, 10-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Momentum (1Y)TBPH logoTBPH+70.4% vs PRGO's -51.2%
Efficiency (ROA)JNJ logoJNJ13.0% ROA vs PRGO's -19.8%, ROIC 20.7% vs 3.7%

TBPH vs PRGO vs JNJ vs HLN vs MCK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TBPHTheravance Biopharma, Inc.
FY 2024
YUPELRI Monotherapy
56.5%$84M
Collaboration revenue
43.5%$64M
PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
HLNHaleon plc
FY 2022
Respiratory Health
100.0%$1.6B
MCKMcKesson Corporation
FY 2025
U.S. Pharmaceutical Segment
91.3%$327.7B
International Segment
4.1%$14.7B
Medical-Surgical Solutions Segment
3.2%$11.4B
Prescription Technology Solutions
1.5%$5.2B

TBPH vs PRGO vs JNJ vs HLN vs MCK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTBPHLAGGINGHLN

Income & Cash Flow (Last 12 Months)

TBPH leads this category, winning 4 of 6 comparable metrics.

MCK is the larger business by revenue, generating $403.4B annually — 5022.3x TBPH's $80M. TBPH is the more profitable business, keeping 36.5% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, TBPH holds the edge at +18.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
RevenueTrailing 12 months$80M$4.2B$92.1B$22.0B$403.4B
EBITDAEarnings before interest/tax-$31M$58M$31.4B$5.3B$6.8B
Net IncomeAfter-tax profit$29M-$1.8B$25.1B$3.2B$4.8B
Free Cash FlowCash after capex$243M$108M$19.1B$3.1B$6.0B
Gross MarginGross profit ÷ Revenue+62.6%+34.2%+68.1%+63.9%+3.6%
Operating MarginEBIT ÷ Revenue-40.9%-4.1%+26.1%+21.4%+1.5%
Net MarginNet income ÷ Revenue+36.5%-43.5%+27.3%+14.5%+1.2%
FCF MarginFCF ÷ Revenue+3.0%+2.6%+20.7%+14.2%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year+18.5%-7.2%+6.8%-0.4%+6.0%
EPS Growth (YoY)Latest quarter vs prior year+126.9%-56.4%+91.0%+18.8%+37.0%
TBPH leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

PRGO leads this category, winning 4 of 7 comparable metrics.

At 19.0x trailing earnings, HLN trades at a 51% valuation discount to JNJ's 38.4x P/E. Adjusting for growth (PEG ratio), MCK offers better value at 0.75x vs JNJ's 34.17x — a lower PEG means you pay less per unit of expected earnings growth.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
Market CapShares × price$862M$1.6B$536.2B$41.4B$92.1B
Enterprise ValueMkt cap + debt − cash$874M$5.1B$548.8B$51.3B$93.8B
Trailing P/EPrice ÷ TTM EPS-14.80x-1.14x38.43x19.01x29.25x
Forward P/EPrice ÷ next-FY EPS est.6.69x5.56x19.20x22.22x19.28x
PEG RatioP/E ÷ EPS growth rate34.17x2.25x0.75x
EV / EBITDAEnterprise value multiple7.42x18.61x13.62x18.74x
Price / SalesMarket cap ÷ Revenue13.40x0.38x6.04x2.83x0.26x
Price / BookPrice ÷ Book value/share4.74x0.55x7.56x1.87x
Price / FCFMarket cap ÷ FCF11.12x27.02x15.47x17.63x
PRGO leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — TBPH and MCK each lead in 3 of 9 comparable metrics.

MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $-51 for PRGO. TBPH carries lower financial leverage with a 0.28x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), HLN scores 8/9 vs PRGO's 4/9, reflecting strong financial health.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
ROE (TTM)Return on equity+14.7%-50.7%+31.7%+19.9%+3.0%
ROA (TTM)Return on assets+7.6%-19.8%+13.0%+10.0%+5.7%
ROICReturn on invested capital-17.2%+3.7%+20.7%+7.6%+5.4%
ROCEReturn on capital employed-13.8%+4.3%+17.6%+8.6%+30.5%
Piotroski ScoreFundamental quality 0–944586
Debt / EquityFinancial leverage0.28x1.35x0.51x0.52x
Net DebtTotal debt minus cash$12M$3.4B$12.5B$7.3B$1.7B
Cash & Equiv.Liquid assets$38M$532M$24.1B$1.3B$5.7B
Total DebtShort + long-term debt$50M$4.0B$36.6B$8.6B$7.4B
Interest CoverageEBIT ÷ Interest expense-11.01x-7.20x48.23x7.80x33.79x
Evenly matched — TBPH and MCK each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

MCK leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $3,986 for PRGO. Over the past 12 months, TBPH leads with a +70.4% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors MCK at 27.3% vs PRGO's -25.2% — a key indicator of consistent wealth creation.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
YTD ReturnYear-to-date-6.2%-13.5%+7.9%-5.6%-8.5%
1-Year ReturnPast 12 months+70.4%-51.2%+44.8%-11.7%+4.6%
3-Year ReturnCumulative with dividends+50.2%-58.1%+46.3%+10.4%+106.4%
5-Year ReturnCumulative with dividends-13.8%-60.1%+46.1%+31.7%+286.9%
10-Year ReturnCumulative with dividends-8.6%-77.7%+132.3%+31.7%+348.1%
CAGR (3Y)Annualised 3-year return+14.5%-25.2%+13.5%+3.4%+27.3%
MCK leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — JNJ and MCK each lead in 1 of 2 comparable metrics.

MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than PRGO's 1.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. JNJ currently trades 88.4% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
Beta (5Y)Sensitivity to S&P 5000.89x1.18x0.06x0.06x0.04x
52-Week HighHighest price in past year$21.03$28.44$251.71$11.42$999.00
52-Week LowLowest price in past year$8.33$9.23$146.12$8.71$637.00
% of 52W HighCurrent price vs 52-week peak+80.9%+41.2%+88.4%+81.5%+75.3%
RSI (14)Momentum oscillator 0–10058.460.937.136.016.2
Avg Volume (50D)Average daily shares traded626K3.4M7.0M8.0M757K
Evenly matched — JNJ and MCK each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — PRGO and JNJ each lead in 1 of 2 comparable metrics.

Analyst consensus: TBPH as "Hold", PRGO as "Hold", JNJ as "Buy", HLN as "Buy", MCK as "Buy". Consensus price targets imply 70.6% upside for PRGO (target: $20) vs 9.6% for HLN (target: $10). For income investors, PRGO offers the higher dividend yield at 9.81% vs MCK's 0.36%.

MetricTBPH logoTBPHTheravance Biopha…PRGO logoPRGOPerrigo Company p…JNJ logoJNJJohnson & JohnsonHLN logoHLNHaleon plcMCK logoMCKMcKesson Corporat…
Analyst RatingConsensus buy/hold/sellHoldHoldBuyBuyBuy
Price TargetConsensus 12-month target$27.00$20.00$249.27$10.20$1006.50
# AnalystsCovering analysts163640431
Dividend YieldAnnual dividend ÷ price+9.8%+2.2%+1.9%+0.4%
Dividend StreakConsecutive years of raises1036217
Dividend / ShareAnnual DPS$1.15$4.87$0.13$2.69
Buyback YieldShare repurchases ÷ mkt cap+0.4%0.0%+0.5%+2.1%+3.4%
Evenly matched — PRGO and JNJ each lead in 1 of 2 comparable metrics.
Key Takeaway

TBPH leads in 1 of 6 categories (Income & Cash Flow). PRGO leads in 1 (Valuation Metrics). 3 tied.

Best OverallTheravance Biopharma, Inc. (TBPH)Leads 1 of 6 categories
Loading custom metrics...

TBPH vs PRGO vs JNJ vs HLN vs MCK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TBPH or PRGO or JNJ or HLN or MCK a better buy right now?

For growth investors, McKesson Corporation (MCK) is the stronger pick with 16.

2% revenue growth year-over-year, versus -4. 0% for Haleon plc (HLN). Haleon plc (HLN) offers the better valuation at 19. 0x trailing P/E (22. 2x forward), making it the more compelling value choice. Analysts rate Johnson & Johnson (JNJ) a "Buy" — based on 40 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TBPH or PRGO or JNJ or HLN or MCK?

On trailing P/E, Haleon plc (HLN) is the cheapest at 19.

0x versus Johnson & Johnson at 38. 4x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: McKesson Corporation wins at 0. 49x versus Johnson & Johnson's 34. 17x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — TBPH or PRGO or JNJ or HLN or MCK?

Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.

9%, compared to -60. 1% for Perrigo Company plc (PRGO). Over 10 years, the gap is even starker: MCK returned +348. 1% versus PRGO's -77. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TBPH or PRGO or JNJ or HLN or MCK?

By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at 0.

04β versus Perrigo Company plc's 1. 18β — meaning PRGO is approximately 2641% more volatile than MCK relative to the S&P 500. On balance sheet safety, Theravance Biopharma, Inc. (TBPH) carries a lower debt/equity ratio of 28% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.

05

Which is growing faster — TBPH or PRGO or JNJ or HLN or MCK?

By revenue growth (latest reported year), McKesson Corporation (MCK) is pulling ahead at 16.

2% versus -4. 0% for Haleon plc (HLN). On earnings-per-share growth, the picture is similar: McKesson Corporation grew EPS 14. 9% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, MCK leads at 10. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TBPH or PRGO or JNJ or HLN or MCK?

Johnson & Johnson (JNJ) is the more profitable company, earning 15.

8% net margin versus -87. 6% for Theravance Biopharma, Inc. — meaning it keeps 15. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JNJ leads at 24. 9% versus -72. 9% for TBPH. At the gross margin level — before operating expenses — TBPH leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TBPH or PRGO or JNJ or HLN or MCK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, McKesson Corporation (MCK) is the more undervalued stock at a PEG of 0. 49x versus Johnson & Johnson's 34. 17x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 6x forward P/E versus 22. 2x for Haleon plc — 16. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 70. 6% to $20. 00.

08

Which pays a better dividend — TBPH or PRGO or JNJ or HLN or MCK?

In this comparison, PRGO (9.

8% yield), JNJ (2. 2% yield), HLN (1. 9% yield), MCK (0. 4% yield) pay a dividend. TBPH does not pay a meaningful dividend and should not be held primarily for income.

09

Is TBPH or PRGO or JNJ or HLN or MCK better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

06), 2. 2% yield, +132. 3% 10Y return). Both have compounded well over 10 years (JNJ: +132. 3%, TBPH: -8. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TBPH and PRGO and JNJ and HLN and MCK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TBPH is a small-cap quality compounder stock; PRGO is a small-cap income-oriented stock; JNJ is a large-cap quality compounder stock; HLN is a mid-cap quality compounder stock; MCK is a mid-cap high-growth stock. PRGO, JNJ, HLN pay a dividend while TBPH, MCK do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Revenue Growth > 5%
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Revenue Growth>
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(TBPH: 18.5% · PRGO: -7.2%)

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