Biotechnology
Compare Stocks
5 / 10Stock Comparison
TELO vs TARA vs ADTX vs NKTR vs ICLR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Medical - Diagnostics & Research
TELO vs TARA vs ADTX vs NKTR vs ICLR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Medical - Diagnostics & Research |
| Market Cap | $45M | $288M | $60K | $1.69B | $9.54B |
| Revenue (TTM) | $0.00 | $0.00 | $6K | $55M | $8.10B |
| Net Income (TTM) | $-10M | $-57M | $-42M | $-164M | $599M |
| Gross Margin | — | — | -34.1% | 99.6% | 26.9% |
| Operating Margin | — | — | -3457.1% | -237.9% | 12.2% |
| Forward P/E | — | — | — | — | 10.5x |
| Total Debt | $0.00 | $3M | $7M | $149M | $3.60B |
| Cash & Equiv. | $7M | $50M | $833K | $15M | $539M |
TELO vs TARA vs ADTX vs NKTR vs ICLR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 24 | May 26 | Return |
|---|---|---|---|
| Telomir Pharmaceuti… (TELO) | 100 | 14.6 | -85.4% |
| Protara Therapeutic… (TARA) | 100 | 117.8 | +17.8% |
| Aditxt, Inc. (ADTX) | 100 | 0.0 | -100.0% |
| Nektar Therapeutics (NKTR) | 100 | 782.8 | +682.8% |
| ICON Public Limited… (ICLR) | 100 | 39.0 | -61.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TELO vs TARA vs ADTX vs NKTR vs ICLR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TELO is the #2 pick in this set and the best alternative if growth is your priority.
- 102.8% revenue growth vs ADTX's -79.2%
TARA ranks third and is worth considering specifically for income & stability and sleep-well-at-night.
- beta 1.16
- Lower volatility, beta 1.16, Low D/E 1.7%, current ratio 14.58x
- Beta 1.16, current ratio 14.58x
- Beta 1.16 vs TELO's 1.91
Among these 5 stocks, ADTX doesn't own a clear edge in any measured category.
NKTR is the clearest fit if your priority is momentum.
- +8.2% vs ADTX's -100.0%
ICLR carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 2.0%, EPS growth 28.8%, 3Y rev CAGR 14.8%
- 91.0% 10Y total return vs NKTR's -59.1%
- 7.4% margin vs ADTX's -7.1K%
- 3.6% ROA vs TELO's -259.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 102.8% revenue growth vs ADTX's -79.2% | |
| Quality / Margins | 7.4% margin vs ADTX's -7.1K% | |
| Stability / Safety | Beta 1.16 vs TELO's 1.91 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +8.2% vs ADTX's -100.0% | |
| Efficiency (ROA) | 3.6% ROA vs TELO's -259.3% |
TELO vs TARA vs ADTX vs NKTR vs ICLR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
TELO vs TARA vs ADTX vs NKTR vs ICLR — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ICLR leads in 2 of 6 categories
ADTX leads 1 • NKTR leads 1 • TELO leads 0 • TARA leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ICLR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ICLR and TARA operate at a comparable scale, with $8.1B and $0 in trailing revenue. ICLR is the more profitable business, keeping 7.4% of every revenue dollar as net income compared to ADTX's -7105.0%. On growth, ICLR holds the edge at +0.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $5,945 | $55M | $8.1B |
| EBITDAEarnings before interest/tax | -$10M | -$64M | -$20M | -$130M | $1.4B |
| Net IncomeAfter-tax profit | -$10M | -$57M | -$42M | -$164M | $599M |
| Free Cash FlowCash after capex | -$4M | -$56M | -$23M | -$209M | $996M |
| Gross MarginGross profit ÷ Revenue | — | — | -34.1% | +99.6% | +26.9% |
| Operating MarginEBIT ÷ Revenue | — | — | -3457.1% | -2.4% | +12.2% |
| Net MarginNet income ÷ Revenue | — | — | -7105.0% | -3.0% | +7.4% |
| FCF MarginFCF ÷ Revenue | — | — | -3799.8% | -3.8% | +12.3% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | -89.1% | -25.3% | +0.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +38.8% | +20.8% | +100.0% | -4.5% | -98.7% |
Valuation Metrics
ADTX leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $45M | $288M | $60,382 | $1.7B | $9.5B |
| Enterprise ValueMkt cap + debt − cash | $38M | $241M | $6M | $1.8B | $12.6B |
| Trailing P/EPrice ÷ TTM EPS | -4.00x | -4.01x | 0.00x | -8.57x | 13.12x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 10.53x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 1.87x |
| EV / EBITDAEnterprise value multiple | — | — | — | — | 7.95x |
| Price / SalesMarket cap ÷ Revenue | — | — | 0.45x | 30.64x | 1.15x |
| Price / BookPrice ÷ Book value/share | 7.07x | 1.17x | 0.00x | 15.66x | 1.09x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 8.53x |
Profitability & Efficiency
ICLR leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
ICLR delivers a 6.3% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-6 for ADTX. TARA carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), ICLR scores 7/9 vs NKTR's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.2% | -36.4% | -6.2% | -4.0% | +6.3% |
| ROA (TTM)Return on assets | -2.6% | -33.8% | -156.6% | -62.8% | +3.6% |
| ROICReturn on invested capital | — | -60.9% | -86.1% | -57.2% | +6.5% |
| ROCEReturn on capital employed | -3.2% | -35.0% | -2.0% | -55.7% | +7.8% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 3 | 4 | 2 | 7 |
| Debt / EquityFinancial leverage | — | 0.02x | 0.84x | 1.66x | 0.38x |
| Net DebtTotal debt minus cash | -$7M | -$46M | $6M | $134M | $3.1B |
| Cash & Equiv.Liquid assets | $7M | $50M | $833,031 | $15M | $539M |
| Total DebtShort + long-term debt | $0 | $3M | $7M | $149M | $3.6B |
| Interest CoverageEBIT ÷ Interest expense | -2574.32x | -40.98x | -19.48x | -4.74x | 3.96x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in TARA five years ago would be worth $5,463 today (with dividends reinvested), compared to $0 for ADTX. Over the past 12 months, NKTR leads with a +818.2% total return vs ADTX's -100.0%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs TELO's -42.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -1.5% | -0.2% | -98.4% | +92.0% | -33.7% |
| 1-Year ReturnPast 12 months | -47.0% | +60.3% | -100.0% | +818.2% | -10.0% |
| 3-Year ReturnCumulative with dividends | -81.1% | +73.8% | -100.0% | +621.8% | -34.1% |
| 5-Year ReturnCumulative with dividends | -81.1% | -45.4% | -100.0% | -72.3% | -45.4% |
| 10-Year ReturnCumulative with dividends | -81.1% | -98.3% | -100.0% | -59.1% | +91.0% |
| CAGR (3Y)Annualised 3-year return | -42.7% | +20.2% | — | +93.3% | -13.0% |
Risk & Volatility
Evenly matched — TARA and NKTR each lead in 1 of 2 comparable metrics.
Risk & Volatility
TARA is the less volatile stock with a 1.16 beta — it tends to amplify market swings less than TELO's 1.91 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NKTR currently trades 76.5% from its 52-week high vs ADTX's 0.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.91x | 1.16x | 1.71x | 1.85x | 1.60x |
| 52-Week HighHighest price in past year | $3.10 | $7.82 | $1979.76 | $109.00 | $211.00 |
| 52-Week LowLowest price in past year | $1.05 | $2.77 | $0.10 | $7.99 | $66.57 |
| % of 52W HighCurrent price vs 52-week peak | +42.6% | +68.7% | +0.0% | +76.5% | +59.2% |
| RSI (14)Momentum oscillator 0–100 | 48.4 | 60.1 | 16.7 | 53.4 | 62.1 |
| Avg Volume (50D)Average daily shares traded | 140K | 741K | 1.9M | 991K | 1.1M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: TARA as "Buy", NKTR as "Buy", ICLR as "Buy". Consensus price targets imply 123.5% upside for TARA (target: $12) vs 19.7% for ICLR (target: $150).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | — | Buy | Buy |
| Price TargetConsensus 12-month target | — | $12.00 | — | $132.83 | $149.63 |
| # AnalystsCovering analysts | — | 5 | — | 33 | 30 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +100.0% | 0.0% | +5.2% |
ICLR leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ADTX leads in 1 (Valuation Metrics). 1 tied.
TELO vs TARA vs ADTX vs NKTR vs ICLR: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is TELO or TARA or ADTX or NKTR or ICLR a better buy right now?
For growth investors, ICON Public Limited Company (ICLR) is the stronger pick with 2.
0% revenue growth year-over-year, versus -79. 2% for Aditxt, Inc. (ADTX). ICON Public Limited Company (ICLR) offers the better valuation at 13. 1x trailing P/E (10. 5x forward), making it the more compelling value choice. Analysts rate Protara Therapeutics, Inc. (TARA) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — TELO or TARA or ADTX or NKTR or ICLR?
Over the past 5 years, Protara Therapeutics, Inc.
(TARA) delivered a total return of -45. 4%, compared to -100. 0% for Aditxt, Inc. (ADTX). Over 10 years, the gap is even starker: ICLR returned +91. 0% versus ADTX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — TELO or TARA or ADTX or NKTR or ICLR?
By beta (market sensitivity over 5 years), Protara Therapeutics, Inc.
(TARA) is the lower-risk stock at 1. 16β versus Telomir Pharmaceuticals, Inc. Common Stock's 1. 91β — meaning TELO is approximately 64% more volatile than TARA relative to the S&P 500. On balance sheet safety, Protara Therapeutics, Inc. (TARA) carries a lower debt/equity ratio of 2% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — TELO or TARA or ADTX or NKTR or ICLR?
By revenue growth (latest reported year), ICON Public Limited Company (ICLR) is pulling ahead at 2.
0% versus -79. 2% for Aditxt, Inc. (ADTX). On earnings-per-share growth, the picture is similar: Telomir Pharmaceuticals, Inc. Common Stock grew EPS 41. 1% year-over-year, compared to -38. 6% for Aditxt, Inc.. Over a 3-year CAGR, ICLR leads at 14. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — TELO or TARA or ADTX or NKTR or ICLR?
ICON Public Limited Company (ICLR) is the more profitable company, earning 9.
6% net margin versus -257. 1% for Aditxt, Inc. — meaning it keeps 9. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ICLR leads at 13. 3% versus -208. 0% for ADTX. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is TELO or TARA or ADTX or NKTR or ICLR more undervalued right now?
Analyst consensus price targets imply the most upside for TARA: 123.
5% to $12. 00.
07Which pays a better dividend — TELO or TARA or ADTX or NKTR or ICLR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is TELO or TARA or ADTX or NKTR or ICLR better for a retirement portfolio?
For long-horizon retirement investors, Protara Therapeutics, Inc.
(TARA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 16)). Telomir Pharmaceuticals, Inc. Common Stock (TELO) carries a higher beta of 1. 91 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TARA: -98. 3%, TELO: -81. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between TELO and TARA and ADTX and NKTR and ICLR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TELO is a small-cap quality compounder stock; TARA is a small-cap quality compounder stock; ADTX is a small-cap quality compounder stock; NKTR is a small-cap quality compounder stock; ICLR is a small-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.