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Stock Comparison

TNYA vs RCKT vs CRSP vs EDIT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TNYA
Tenaya Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$184M
5Y Perf.-94.5%
RCKT
Rocket Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$398M
5Y Perf.-89.8%
CRSP
CRISPR Therapeutics AG

Biotechnology

HealthcareNASDAQ • CH
Market Cap$5.06B
5Y Perf.-56.7%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-92.8%

TNYA vs RCKT vs CRSP vs EDIT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TNYA logoTNYA
RCKT logoRCKT
CRSP logoCRSP
EDIT logoEDIT
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$184M$398M$5.06B$297M
Revenue (TTM)$0.00$0.00$4M$0.00
Net Income (TTM)$-91M$-223M$-569M$-160M
Gross Margin-41.7%
Operating Margin-134.1%
Total Debt$11M$25M$395M$18M
Cash & Equiv.$101M$78M$355M$147M

TNYA vs RCKT vs CRSP vs EDITLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TNYA
RCKT
CRSP
EDIT
StockJul 21May 26Return
Tenaya Therapeutics… (TNYA)1005.5-94.5%
Rocket Pharmaceutic… (RCKT)10010.2-89.8%
CRISPR Therapeutics… (CRSP)10043.3-56.7%
Editas Medicine, In… (EDIT)1007.2-92.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: TNYA vs RCKT vs CRSP vs EDIT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TNYA leads in 2 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Rocket Pharmaceuticals, Inc. is the stronger pick specifically for capital preservation and lower volatility. CRSP and EDIT also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TNYA
Tenaya Therapeutics, Inc.
The Growth Leader

TNYA carries the broadest edge in this set and is the clearest fit for growth and quality.

  • 11.8% revenue growth vs EDIT's -100.0%
  • 1.8% margin vs CRSP's -138.6%
Best for: growth and quality
RCKT
Rocket Pharmaceuticals, Inc.
The Income Pick

RCKT is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 1.31
  • Lower volatility, beta 1.31, Low D/E 9.0%, current ratio 6.38x
  • Beta 1.31 vs TNYA's 2.80
Best for: income & stability and sleep-well-at-night
CRSP
CRISPR Therapeutics AG
The Growth Play

CRSP is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth -90.0%, EPS growth -49.1%, 3Y rev CAGR 100.4%
  • 272.0% 10Y total return vs EDIT's -90.0%
  • Beta 1.93, current ratio 13.32x
  • -24.5% ROA vs EDIT's -74.2%
Best for: growth exposure and long-term compounding
EDIT
Editas Medicine, Inc.
The Momentum Pick

EDIT is the clearest fit if your priority is momentum.

  • +127.8% vs RCKT's -45.2%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthTNYA logoTNYA11.8% revenue growth vs EDIT's -100.0%
Quality / MarginsTNYA logoTNYA1.8% margin vs CRSP's -138.6%
Stability / SafetyRCKT logoRCKTBeta 1.31 vs TNYA's 2.80
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)EDIT logoEDIT+127.8% vs RCKT's -45.2%
Efficiency (ROA)CRSP logoCRSP-24.5% ROA vs EDIT's -74.2%

TNYA vs RCKT vs CRSP vs EDIT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TNYATenaya Therapeutics, Inc.

Segment breakdown not available.

RCKTRocket Pharmaceuticals, Inc.

Segment breakdown not available.

CRSPCRISPR Therapeutics AG
FY 2025
Grant
100.0%$4M
EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M

TNYA vs RCKT vs CRSP vs EDIT — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCRSPLAGGINGEDIT

Income & Cash Flow (Last 12 Months)

Evenly matched — CRSP and EDIT each lead in 1 of 2 comparable metrics.

CRSP and EDIT operate at a comparable scale, with $4M and $0 in trailing revenue. On growth, CRSP holds the edge at +68.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
RevenueTrailing 12 months$0$0$4M$0
EBITDAEarnings before interest/tax-$93M-$232M-$535M$0
Net IncomeAfter-tax profit-$91M-$223M-$569M-$160M
Free Cash FlowCash after capex-$69M-$190M-$401M-$166M
Gross MarginGross profit ÷ Revenue-41.7%
Operating MarginEBIT ÷ Revenue-134.1%
Net MarginNet income ÷ Revenue-138.6%
FCF MarginFCF ÷ Revenue-97.8%
Rev. Growth (YoY)Latest quarter vs prior year+68.6%-151.6%
EPS Growth (YoY)Latest quarter vs prior year+57.1%+38.7%+19.0%+105.5%
Evenly matched — CRSP and EDIT each lead in 1 of 2 comparable metrics.

Valuation Metrics

Evenly matched — TNYA and CRSP each lead in 1 of 2 comparable metrics.
MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Market CapShares × price$184M$398M$5.1B$297M
Enterprise ValueMkt cap + debt − cash$94M$345M$5.1B$168M
Trailing P/EPrice ÷ TTM EPS-1.44x-1.83x-8.10x-1.68x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue1440.41x
Price / BookPrice ÷ Book value/share1.05x1.47x2.45x9.85x
Price / FCFMarket cap ÷ FCF
Evenly matched — TNYA and CRSP each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

CRSP leads this category, winning 4 of 8 comparable metrics.

CRSP delivers a -30.9% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-5 for EDIT. TNYA carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), TNYA scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.

MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
ROE (TTM)Return on equity-85.2%-80.5%-30.9%-5.2%
ROA (TTM)Return on assets-70.0%-67.5%-24.5%-74.2%
ROICReturn on invested capital-103.2%-63.2%-22.3%
ROCEReturn on capital employed-79.3%-58.9%-26.6%
Piotroski ScoreFundamental quality 0–94111
Debt / EquityFinancial leverage0.09x0.09x0.21x0.66x
Net DebtTotal debt minus cash-$90M-$53M$40M-$129M
Cash & Equiv.Liquid assets$101M$78M$355M$147M
Total DebtShort + long-term debt$11M$25M$395M$18M
Interest CoverageEBIT ÷ Interest expense
CRSP leads this category, winning 4 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

CRSP leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in CRSP five years ago would be worth $4,867 today (with dividends reinvested), compared to $553 for TNYA. Over the past 12 months, EDIT leads with a +127.8% total return vs RCKT's -45.2%. The 3-year compound annual growth rate (CAGR) favors CRSP at -2.2% vs TNYA's -49.0% — a key indicator of consistent wealth creation.

MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
YTD ReturnYear-to-date+15.4%+6.1%-2.5%+47.8%
1-Year ReturnPast 12 months+88.6%-45.2%+53.1%+127.8%
3-Year ReturnCumulative with dividends-86.7%-82.8%-6.3%-68.5%
5-Year ReturnCumulative with dividends-94.5%-91.6%-51.3%-91.1%
10-Year ReturnCumulative with dividends-94.5%-91.3%+272.0%-90.0%
CAGR (3Y)Annualised 3-year return-49.0%-44.4%-2.2%-32.0%
CRSP leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — RCKT and CRSP each lead in 1 of 2 comparable metrics.

RCKT is the less volatile stock with a 1.31 beta — it tends to amplify market swings less than TNYA's 2.80 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CRSP currently trades 66.8% from its 52-week high vs TNYA's 36.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Beta (5Y)Sensitivity to S&P 5002.80x1.31x1.93x2.52x
52-Week HighHighest price in past year$2.35$7.39$78.48$4.54
52-Week LowLowest price in past year$0.36$2.19$33.50$1.29
% of 52W HighCurrent price vs 52-week peak+36.1%+49.7%+66.8%+66.7%
RSI (14)Momentum oscillator 0–10057.354.455.557.5
Avg Volume (50D)Average daily shares traded4.2M3.5M2.0M1.6M
Evenly matched — RCKT and CRSP each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: TNYA as "Buy", RCKT as "Buy", CRSP as "Buy", EDIT as "Buy". Consensus price targets imply 174.6% upside for TNYA (target: $2) vs 20.2% for CRSP (target: $63).

MetricTNYA logoTNYATenaya Therapeuti…RCKT logoRCKTRocket Pharmaceut…CRSP logoCRSPCRISPR Therapeuti…EDIT logoEDITEditas Medicine, …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$2.33$5.00$63.00$6.00
# AnalystsCovering analysts6193825
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

CRSP leads in 2 of 6 categories — strongest in Profitability & Efficiency and Total Returns. 3 categories are tied.

Best OverallCRISPR Therapeutics AG (CRSP)Leads 2 of 6 categories
Loading custom metrics...

TNYA vs RCKT vs CRSP vs EDIT: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is TNYA or RCKT or CRSP or EDIT a better buy right now?

For growth investors, CRISPR Therapeutics AG (CRSP) is the stronger pick with -90.

0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Tenaya Therapeutics, Inc. (TNYA) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — TNYA or RCKT or CRSP or EDIT?

Over the past 5 years, CRISPR Therapeutics AG (CRSP) delivered a total return of -51.

3%, compared to -94. 5% for Tenaya Therapeutics, Inc. (TNYA). Over 10 years, the gap is even starker: CRSP returned +272. 0% versus TNYA's -94. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — TNYA or RCKT or CRSP or EDIT?

By beta (market sensitivity over 5 years), Rocket Pharmaceuticals, Inc.

(RCKT) is the lower-risk stock at 1. 31β versus Tenaya Therapeutics, Inc. 's 2. 80β — meaning TNYA is approximately 113% more volatile than RCKT relative to the S&P 500. On balance sheet safety, Tenaya Therapeutics, Inc. (TNYA) carries a lower debt/equity ratio of 9% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — TNYA or RCKT or CRSP or EDIT?

By revenue growth (latest reported year), CRISPR Therapeutics AG (CRSP) is pulling ahead at -90.

0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Tenaya Therapeutics, Inc. grew EPS 55. 0% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — TNYA or RCKT or CRSP or EDIT?

Tenaya Therapeutics, Inc.

(TNYA) is the more profitable company, earning 0. 0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TNYA leads at 0. 0% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — TNYA leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — TNYA or RCKT or CRSP or EDIT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is TNYA or RCKT or CRSP or EDIT better for a retirement portfolio?

For long-horizon retirement investors, Rocket Pharmaceuticals, Inc.

(RCKT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Tenaya Therapeutics, Inc. (TNYA) carries a higher beta of 2. 80 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RCKT: -91. 3%, TNYA: -94. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between TNYA and RCKT and CRSP and EDIT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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