Biotechnology
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TOVX vs NKTR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
TOVX vs NKTR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $13M | $1.69B |
| Revenue (TTM) | $0.00 | $55M |
| Net Income (TTM) | $-23M | $-164M |
| Gross Margin | — | 99.6% |
| Operating Margin | — | -237.9% |
| Total Debt | $3M | $149M |
| Cash & Equiv. | $13M | $15M |
TOVX vs NKTR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Theriva Biologics, … (TOVX) | 100 | 0.4 | -99.6% |
| Nektar Therapeutics (NKTR) | 100 | 25.6 | -74.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TOVX vs NKTR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TOVX is the clearest fit if your priority is growth exposure.
- EPS growth 89.1%
- 7.4% revenue growth vs NKTR's -43.9%
- 0.8% margin vs NKTR's -297.1%
NKTR carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.85
- -59.1% 10Y total return vs TOVX's -100.0%
- Lower volatility, beta 1.85, current ratio 4.97x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 7.4% revenue growth vs NKTR's -43.9% | |
| Quality / Margins | 0.8% margin vs NKTR's -297.1% | |
| Stability / Safety | Beta 1.85 vs TOVX's 2.08 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +8.2% vs TOVX's -55.6% | |
| Efficiency (ROA) | -62.8% ROA vs TOVX's -64.2%, ROIC -57.2% vs -161.2% |
TOVX vs NKTR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
TOVX vs NKTR — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
TOVX leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
NKTR and TOVX operate at a comparable scale, with $55M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $55M |
| EBITDAEarnings before interest/tax | -$13M | -$130M |
| Net IncomeAfter-tax profit | -$23M | -$164M |
| Free Cash FlowCash after capex | -$14M | -$209M |
| Gross MarginGross profit ÷ Revenue | — | +99.6% |
| Operating MarginEBIT ÷ Revenue | — | -2.4% |
| Net MarginNet income ÷ Revenue | — | -3.0% |
| FCF MarginFCF ÷ Revenue | — | -3.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -25.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +96.8% | -4.5% |
Valuation Metrics
Evenly matched — TOVX and NKTR each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $13M | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $2M | $1.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.17x | -8.57x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 30.64x |
| Price / BookPrice ÷ Book value/share | 0.28x | 15.66x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
TOVX leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
TOVX delivers a -190.8% return on equity — every $100 of shareholder capital generates $-191 in annual profit, vs $-4 for NKTR. TOVX carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), NKTR scores 2/9 vs TOVX's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -190.8% | -4.0% |
| ROA (TTM)Return on assets | -64.2% | -62.8% |
| ROICReturn on invested capital | -161.2% | -57.2% |
| ROCEReturn on capital employed | -53.7% | -55.7% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 |
| Debt / EquityFinancial leverage | 0.17x | 1.66x |
| Net DebtTotal debt minus cash | -$10M | $134M |
| Cash & Equiv.Liquid assets | $13M | $15M |
| Total DebtShort + long-term debt | $3M | $149M |
| Interest CoverageEBIT ÷ Interest expense | — | -4.74x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NKTR five years ago would be worth $2,765 today (with dividends reinvested), compared to $28 for TOVX. Over the past 12 months, NKTR leads with a +818.2% total return vs TOVX's -55.6%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs TOVX's -73.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +38.5% | +92.0% |
| 1-Year ReturnPast 12 months | -55.6% | +818.2% |
| 3-Year ReturnCumulative with dividends | -98.0% | +621.8% |
| 5-Year ReturnCumulative with dividends | -99.7% | -72.3% |
| 10-Year ReturnCumulative with dividends | -100.0% | -59.1% |
| CAGR (3Y)Annualised 3-year return | -73.0% | +93.3% |
Risk & Volatility
NKTR leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
NKTR is the less volatile stock with a 1.85 beta — it tends to amplify market swings less than TOVX's 2.08 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NKTR currently trades 76.5% from its 52-week high vs TOVX's 24.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.08x | 1.85x |
| 52-Week HighHighest price in past year | $1.45 | $109.00 |
| 52-Week LowLowest price in past year | $0.16 | $7.99 |
| % of 52W HighCurrent price vs 52-week peak | +24.8% | +76.5% |
| RSI (14)Momentum oscillator 0–100 | 60.0 | 53.4 |
| Avg Volume (50D)Average daily shares traded | 22.9M | 991K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $132.83 |
| # AnalystsCovering analysts | — | 33 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
TOVX leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NKTR leads in 2 (Total Returns, Risk & Volatility). 1 tied.
TOVX vs NKTR: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is TOVX or NKTR a better buy right now?
Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison.
The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — TOVX or NKTR?
Over the past 5 years, Nektar Therapeutics (NKTR) delivered a total return of -72.
3%, compared to -99. 7% for Theriva Biologics, Inc. (TOVX). Over 10 years, the gap is even starker: NKTR returned -59. 1% versus TOVX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — TOVX or NKTR?
By beta (market sensitivity over 5 years), Nektar Therapeutics (NKTR) is the lower-risk stock at 1.
85β versus Theriva Biologics, Inc. 's 2. 08β — meaning TOVX is approximately 13% more volatile than NKTR relative to the S&P 500. On balance sheet safety, Theriva Biologics, Inc. (TOVX) carries a lower debt/equity ratio of 17% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.
04Which is growing faster — TOVX or NKTR?
On earnings-per-share growth, the picture is similar: Theriva Biologics, Inc.
grew EPS 89. 1% year-over-year, compared to -12. 1% for Nektar Therapeutics. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — TOVX or NKTR?
Theriva Biologics, Inc.
(TOVX) is the more profitable company, earning 0. 0% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TOVX leads at 0. 0% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — TOVX or NKTR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is TOVX or NKTR better for a retirement portfolio?
For long-horizon retirement investors, Nektar Therapeutics (NKTR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.
Theriva Biologics, Inc. (TOVX) carries a higher beta of 2. 08 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NKTR: -59. 1%, TOVX: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between TOVX and NKTR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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