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Stock Comparison

TVTX vs PTCT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TVTX
Travere Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.97B
5Y Perf.+172.0%
PTCT
PTC Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.35B
5Y Perf.+27.2%

TVTX vs PTCT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TVTX logoTVTX
PTCT logoPTCT
IndustryBiotechnologyBiotechnology
Market Cap$3.97B$5.35B
Revenue (TTM)$536M$827M
Net Income (TTM)$-21M$-187M
Gross Margin75.2%49.7%
Operating Margin-10.6%-8.3%
Forward P/E152.9x8.3x
Total Debt$329M$492M
Cash & Equiv.$93M$985M

TVTX vs PTCTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TVTX
PTCT
StockMay 20May 26Return
Travere Therapeutic… (TVTX)100272.0+172.0%
PTC Therapeutics, I… (PTCT)100127.2+27.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: TVTX vs PTCT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TVTX and PTCT are tied at the top with 3 categories each — the right choice depends on your priorities. PTC Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
TVTX
Travere Therapeutics, Inc.
The Quality Compounder

TVTX has the current edge in this matchup, primarily because of its strength in quality and momentum.

  • -4.0% margin vs PTCT's -22.6%
  • +110.9% vs PTCT's +58.2%
  • -3.8% ROA vs PTCT's -6.8%
Best for: quality and momentum
PTCT
PTC Therapeutics, Inc.
The Income Pick

PTCT is the clearest fit if your priority is income & stability and growth exposure.

  • beta 1.13
  • Rev growth 114.5%, EPS growth 264.5%, 3Y rev CAGR 35.3%
  • 7.3% 10Y total return vs TVTX's 179.0%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthPTCT logoPTCT114.5% revenue growth vs TVTX's 110.5%
ValuePTCT logoPTCTLower P/E (8.3x vs 152.9x)
Quality / MarginsTVTX logoTVTX-4.0% margin vs PTCT's -22.6%
Stability / SafetyPTCT logoPTCTBeta 1.13 vs TVTX's 1.81
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)TVTX logoTVTX+110.9% vs PTCT's +58.2%
Efficiency (ROA)TVTX logoTVTX-3.8% ROA vs PTCT's -6.8%

TVTX vs PTCT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TVTXTravere Therapeutics, Inc.
FY 2025
Product
83.6%$410M
License
16.4%$80M
PTCTPTC Therapeutics, Inc.
FY 2025
Collaboration and License Revenue
54.6%$998M
Product
32.1%$587M
Royalty
13.4%$244M

TVTX vs PTCT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTVTXLAGGINGPTCT

Income & Cash Flow (Last 12 Months)

TVTX leads this category, winning 5 of 6 comparable metrics.

PTCT is the larger business by revenue, generating $827M annually — 1.5x TVTX's $536M. TVTX is the more profitable business, keeping -4.0% of every revenue dollar as net income compared to PTCT's -22.6%. On growth, TVTX holds the edge at +55.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
RevenueTrailing 12 months$536M$827M
EBITDAEarnings before interest/tax-$9M-$37M
Net IncomeAfter-tax profit-$21M-$187M
Free Cash FlowCash after capex$17M-$229M
Gross MarginGross profit ÷ Revenue+75.2%+49.7%
Operating MarginEBIT ÷ Revenue-10.6%-8.3%
Net MarginNet income ÷ Revenue-4.0%-22.6%
FCF MarginFCF ÷ Revenue+3.3%-27.7%
Rev. Growth (YoY)Latest quarter vs prior year+55.6%-76.8%
EPS Growth (YoY)Latest quarter vs prior year+14.9%-100.3%
TVTX leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PTCT leads this category, winning 2 of 3 comparable metrics.
MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
Market CapShares × price$4.0B$5.3B
Enterprise ValueMkt cap + debt − cash$4.2B$4.9B
Trailing P/EPrice ÷ TTM EPS-76.18x8.29x
Forward P/EPrice ÷ next-FY EPS est.152.90x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple5.42x
Price / SalesMarket cap ÷ Revenue8.08x3.09x
Price / BookPrice ÷ Book value/share33.14x
Price / FCFMarket cap ÷ FCF104.99x7.61x
PTCT leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

TVTX leads this category, winning 3 of 5 comparable metrics.
MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
ROE (TTM)Return on equity-26.8%
ROA (TTM)Return on assets-3.8%-6.8%
ROICReturn on invested capital-12.5%
ROCEReturn on capital employed-15.0%+55.9%
Piotroski ScoreFundamental quality 0–977
Debt / EquityFinancial leverage2.86x
Net DebtTotal debt minus cash$236M-$492M
Cash & Equiv.Liquid assets$93M$985M
Total DebtShort + long-term debt$329M$492M
Interest CoverageEBIT ÷ Interest expense-0.03x-1.67x
TVTX leads this category, winning 3 of 5 comparable metrics.

Total Returns (Dividends Reinvested)

TVTX leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in TVTX five years ago would be worth $21,319 today (with dividends reinvested), compared to $16,026 for PTCT. Over the past 12 months, TVTX leads with a +110.9% total return vs PTCT's +58.2%. The 3-year compound annual growth rate (CAGR) favors TVTX at 36.6% vs PTCT's 5.1% — a key indicator of consistent wealth creation.

MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
YTD ReturnYear-to-date+7.9%-16.0%
1-Year ReturnPast 12 months+110.9%+58.2%
3-Year ReturnCumulative with dividends+154.8%+16.1%
5-Year ReturnCumulative with dividends+113.2%+60.3%
10-Year ReturnCumulative with dividends+179.0%+733.2%
CAGR (3Y)Annualised 3-year return+36.6%+5.1%
TVTX leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — TVTX and PTCT each lead in 1 of 2 comparable metrics.

PTCT is the less volatile stock with a 1.13 beta — it tends to amplify market swings less than TVTX's 1.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TVTX currently trades 87.9% from its 52-week high vs PTCT's 73.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
Beta (5Y)Sensitivity to S&P 5001.81x1.13x
52-Week HighHighest price in past year$48.52$87.50
52-Week LowLowest price in past year$13.88$37.94
% of 52W HighCurrent price vs 52-week peak+87.9%+73.7%
RSI (14)Momentum oscillator 0–10072.145.3
Avg Volume (50D)Average daily shares traded2.0M1.0M
Evenly matched — TVTX and PTCT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates TVTX as "Buy" and PTCT as "Buy". Consensus price targets imply 39.0% upside for PTCT (target: $90) vs 20.7% for TVTX (target: $52).

MetricTVTX logoTVTXTravere Therapeut…PTCT logoPTCTPTC Therapeutics,…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$51.50$89.67
# AnalystsCovering analysts1826
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

TVTX leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PTCT leads in 1 (Valuation Metrics). 1 tied.

Best OverallTravere Therapeutics, Inc. (TVTX)Leads 3 of 6 categories
Loading custom metrics...

TVTX vs PTCT: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is TVTX or PTCT a better buy right now?

For growth investors, PTC Therapeutics, Inc.

(PTCT) is the stronger pick with 114. 5% revenue growth year-over-year, versus 110. 5% for Travere Therapeutics, Inc. (TVTX). PTC Therapeutics, Inc. (PTCT) offers the better valuation at 8. 3x trailing P/E, making it the more compelling value choice. Analysts rate Travere Therapeutics, Inc. (TVTX) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — TVTX or PTCT?

Over the past 5 years, Travere Therapeutics, Inc.

(TVTX) delivered a total return of +113. 2%, compared to +60. 3% for PTC Therapeutics, Inc. (PTCT). Over 10 years, the gap is even starker: PTCT returned +733. 2% versus TVTX's +179. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — TVTX or PTCT?

By beta (market sensitivity over 5 years), PTC Therapeutics, Inc.

(PTCT) is the lower-risk stock at 1. 13β versus Travere Therapeutics, Inc. 's 1. 81β — meaning TVTX is approximately 59% more volatile than PTCT relative to the S&P 500.

04

Which is growing faster — TVTX or PTCT?

By revenue growth (latest reported year), PTC Therapeutics, Inc.

(PTCT) is pulling ahead at 114. 5% versus 110. 5% for Travere Therapeutics, Inc. (TVTX). On earnings-per-share growth, the picture is similar: PTC Therapeutics, Inc. grew EPS 264. 5% year-over-year, compared to 86. 3% for Travere Therapeutics, Inc.. Over a 3-year CAGR, TVTX leads at 64. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — TVTX or PTCT?

PTC Therapeutics, Inc.

(PTCT) is the more profitable company, earning 39. 4% net margin versus -5. 2% for Travere Therapeutics, Inc. — meaning it keeps 39. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PTCT leads at 49. 5% versus -12. 8% for TVTX. At the gross margin level — before operating expenses — TVTX leads at 97. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is TVTX or PTCT more undervalued right now?

Analyst consensus price targets imply the most upside for PTCT: 39.

0% to $89. 67.

07

Which pays a better dividend — TVTX or PTCT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is TVTX or PTCT better for a retirement portfolio?

For long-horizon retirement investors, PTC Therapeutics, Inc.

(PTCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 13), +733. 2% 10Y return). Travere Therapeutics, Inc. (TVTX) carries a higher beta of 1. 81 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PTCT: +733. 2%, TVTX: +179. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between TVTX and PTCT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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TVTX

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 27%
  • Gross Margin > 45%
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PTCT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 29%
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Revenue Growth>
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(TVTX: 55.6% · PTCT: -76.8%)

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