Drug Manufacturers - Specialty & Generic
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TXMD vs ANIP vs TEVA vs MCK
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Medical - Distribution
TXMD vs ANIP vs TEVA vs MCK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Medical - Distribution |
| Market Cap | $23M | $1.78B | $41.93B | $92.15B |
| Revenue (TTM) | $3M | $883M | $17.35B | $403.43B |
| Net Income (TTM) | $302K | $78M | $1.56B | $4.76B |
| Gross Margin | 96.6% | 69.1% | 52.1% | 3.6% |
| Operating Margin | -97.1% | 12.6% | 13.2% | 1.5% |
| Forward P/E | — | 9.2x | 14.5x | 19.3x |
| Total Debt | $7M | $325M | $17.38B | $7.39B |
| Cash & Equiv. | $5M | $286M | $3.56B | $5.69B |
TXMD vs ANIP vs TEVA vs MCK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| TherapeuticsMD, Inc. (TXMD) | 100 | 3.6 | -96.4% |
| ANI Pharmaceuticals… (ANIP) | 100 | 270.2 | +170.2% |
| Teva Pharmaceutical… (TEVA) | 100 | 287.4 | +187.4% |
| McKesson Corporation (MCK) | 100 | 474.1 | +374.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TXMD vs ANIP vs TEVA vs MCK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TXMD is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.51, Low D/E 26.2%, current ratio 1.92x
- 10.8% margin vs MCK's 1.2%
ANIP is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 43.8%, EPS growth 419.2%, 3Y rev CAGR 40.8%
- 43.8% revenue growth vs TEVA's 4.3%
- Lower P/E (9.2x vs 19.3x)
TEVA is the clearest fit if your priority is momentum.
- +104.6% vs MCK's +4.6%
MCK carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- Dividend streak 17 yrs, beta 0.04, yield 0.4%
- 348.1% 10Y total return vs ANIP's 84.7%
- Beta 0.04, yield 0.4%, current ratio 0.90x
- Beta 0.04 vs TEVA's 1.13
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 43.8% revenue growth vs TEVA's 4.3% | |
| Value | Lower P/E (9.2x vs 19.3x) | |
| Quality / Margins | 10.8% margin vs MCK's 1.2% | |
| Stability / Safety | Beta 0.04 vs TEVA's 1.13 | |
| Dividends | 0.4% yield, 17-year raise streak, vs ANIP's 0.1%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +104.6% vs MCK's +4.6% | |
| Efficiency (ROA) | 5.7% ROA vs TXMD's 0.8%, ROIC 5.4% vs -11.4% |
TXMD vs ANIP vs TEVA vs MCK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
TXMD vs ANIP vs TEVA vs MCK — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MCK leads in 2 of 6 categories
TXMD leads 1 • ANIP leads 1 • TEVA leads 1 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
TXMD leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MCK is the larger business by revenue, generating $403.4B annually — 144288.3x TXMD's $3M. TXMD is the more profitable business, keeping 10.8% of every revenue dollar as net income compared to MCK's 1.2%. On growth, TXMD holds the edge at +43.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $3M | $883M | $17.3B | $403.4B |
| EBITDAEarnings before interest/tax | -$2M | $203M | $3.3B | $6.8B |
| Net IncomeAfter-tax profit | $302,000 | $78M | $1.6B | $4.8B |
| Free Cash FlowCash after capex | $2M | $128M | $1.2B | $6.0B |
| Gross MarginGross profit ÷ Revenue | +96.6% | +69.1% | +52.1% | +3.6% |
| Operating MarginEBIT ÷ Revenue | -97.1% | +12.6% | +13.2% | +1.5% |
| Net MarginNet income ÷ Revenue | +10.8% | +8.9% | +9.0% | +1.2% |
| FCF MarginFCF ÷ Revenue | +74.0% | +14.5% | +6.8% | +1.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | +43.3% | +29.6% | +2.3% | +6.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +118.9% | +3.1% | +72.2% | +37.0% |
Valuation Metrics
ANIP leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 25.3x trailing earnings, ANIP trades at a 16% valuation discount to TEVA's 30.0x P/E. On an enterprise value basis, ANIP's 9.0x EV/EBITDA is more attractive than MCK's 18.7x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $23M | $1.8B | $41.9B | $92.1B |
| Enterprise ValueMkt cap + debt − cash | $25M | $1.8B | $55.8B | $93.8B |
| Trailing P/EPrice ÷ TTM EPS | -10.58x | 25.27x | 30.01x | 29.25x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 9.25x | 14.55x | 19.28x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.75x |
| EV / EBITDAEnterprise value multiple | — | 8.99x | 17.65x | 18.74x |
| Price / SalesMarket cap ÷ Revenue | 13.21x | 2.02x | 2.43x | 0.26x |
| Price / BookPrice ÷ Book value/share | 0.85x | 3.29x | 5.34x | — |
| Price / FCFMarket cap ÷ FCF | 31.78x | 9.62x | 36.52x | 17.63x |
Profitability & Efficiency
MCK leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $1 for TXMD. TXMD carries lower financial leverage with a 0.26x debt-to-equity ratio, signaling a more conservative balance sheet compared to TEVA's 2.20x. On the Piotroski fundamental quality scale (0–9), TEVA scores 8/9 vs MCK's 6/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +1.1% | +14.5% | +20.7% | +3.0% |
| ROA (TTM)Return on assets | +0.8% | +5.4% | +3.9% | +5.7% |
| ROICReturn on invested capital | -11.4% | +11.2% | +7.7% | +5.4% |
| ROCEReturn on capital employed | -13.6% | +9.9% | +8.0% | +30.5% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 6 | 8 | 6 |
| Debt / EquityFinancial leverage | 0.26x | 0.60x | 2.20x | — |
| Net DebtTotal debt minus cash | $2M | $40M | $13.8B | $1.7B |
| Cash & Equiv.Liquid assets | $5M | $286M | $3.6B | $5.7B |
| Total DebtShort + long-term debt | $7M | $325M | $17.4B | $7.4B |
| Interest CoverageEBIT ÷ Interest expense | -194.43x | 1.82x | 2.51x | 33.79x |
Total Returns (Dividends Reinvested)
TEVA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $369 for TXMD. Over the past 12 months, TEVA leads with a +104.6% total return vs MCK's +4.6%. The 3-year compound annual growth rate (CAGR) favors TEVA at 58.4% vs TXMD's -19.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +21.8% | +7.0% | +16.3% | -8.5% |
| 1-Year ReturnPast 12 months | +45.7% | +18.5% | +104.6% | +4.6% |
| 3-Year ReturnCumulative with dividends | -48.2% | +97.1% | +297.5% | +106.4% |
| 5-Year ReturnCumulative with dividends | -96.3% | +117.4% | +246.2% | +286.9% |
| 10-Year ReturnCumulative with dividends | -99.5% | +84.7% | -28.3% | +348.1% |
| CAGR (3Y)Annualised 3-year return | -19.7% | +25.4% | +58.4% | +27.3% |
Risk & Volatility
Evenly matched — TEVA and MCK each lead in 1 of 2 comparable metrics.
Risk & Volatility
MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than TEVA's 1.13 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TEVA currently trades 96.4% from its 52-week high vs TXMD's 68.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 0.63x | 1.13x | 0.04x |
| 52-Week HighHighest price in past year | $2.95 | $99.50 | $37.35 | $999.00 |
| 52-Week LowLowest price in past year | $0.98 | $56.71 | $14.99 | $637.00 |
| % of 52W HighCurrent price vs 52-week peak | +68.1% | +84.3% | +96.4% | +75.3% |
| RSI (14)Momentum oscillator 0–100 | 43.3 | 64.4 | 73.5 | 16.2 |
| Avg Volume (50D)Average daily shares traded | 21K | 328K | 6.6M | 757K |
Analyst Outlook
MCK leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ANIP as "Buy", TEVA as "Buy", MCK as "Buy". Consensus price targets imply 47.8% upside for ANIP (target: $124) vs 8.3% for TEVA (target: $39). MCK is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $124.00 | $39.00 | $1006.50 |
| # AnalystsCovering analysts | — | 10 | 46 | 31 |
| Dividend YieldAnnual dividend ÷ price | — | +0.1% | — | +0.4% |
| Dividend StreakConsecutive years of raises | 1 | 0 | 1 | 17 |
| Dividend / ShareAnnual DPS | — | $0.05 | — | $2.69 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.7% | 0.0% | +3.4% |
MCK leads in 2 of 6 categories (Profitability & Efficiency, Analyst Outlook). TXMD leads in 1 (Income & Cash Flow). 1 tied.
TXMD vs ANIP vs TEVA vs MCK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TXMD or ANIP or TEVA or MCK a better buy right now?
For growth investors, ANI Pharmaceuticals, Inc.
(ANIP) is the stronger pick with 43. 8% revenue growth year-over-year, versus 4. 3% for Teva Pharmaceutical Industries Limited (TEVA). ANI Pharmaceuticals, Inc. (ANIP) offers the better valuation at 25. 3x trailing P/E (9. 2x forward), making it the more compelling value choice. Analysts rate ANI Pharmaceuticals, Inc. (ANIP) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TXMD or ANIP or TEVA or MCK?
On trailing P/E, ANI Pharmaceuticals, Inc.
(ANIP) is the cheapest at 25. 3x versus Teva Pharmaceutical Industries Limited at 30. 0x. On forward P/E, ANI Pharmaceuticals, Inc. is actually cheaper at 9. 2x.
03Which is the better long-term investment — TXMD or ANIP or TEVA or MCK?
Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.
9%, compared to -96. 3% for TherapeuticsMD, Inc. (TXMD). Over 10 years, the gap is even starker: MCK returned +348. 1% versus TXMD's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TXMD or ANIP or TEVA or MCK?
By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at 0.
04β versus Teva Pharmaceutical Industries Limited's 1. 13β — meaning TEVA is approximately 2525% more volatile than MCK relative to the S&P 500. On balance sheet safety, TherapeuticsMD, Inc. (TXMD) carries a lower debt/equity ratio of 26% versus 2% for Teva Pharmaceutical Industries Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — TXMD or ANIP or TEVA or MCK?
By revenue growth (latest reported year), ANI Pharmaceuticals, Inc.
(ANIP) is pulling ahead at 43. 8% versus 4. 3% for Teva Pharmaceutical Industries Limited (TEVA). On earnings-per-share growth, the picture is similar: ANI Pharmaceuticals, Inc. grew EPS 419. 2% year-over-year, compared to 14. 9% for McKesson Corporation. Over a 3-year CAGR, ANIP leads at 40. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TXMD or ANIP or TEVA or MCK?
ANI Pharmaceuticals, Inc.
(ANIP) is the more profitable company, earning 8. 9% net margin versus -123. 9% for TherapeuticsMD, Inc. — meaning it keeps 8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ANIP leads at 12. 6% versus -270. 3% for TXMD. At the gross margin level — before operating expenses — TXMD leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TXMD or ANIP or TEVA or MCK more undervalued right now?
On forward earnings alone, ANI Pharmaceuticals, Inc.
(ANIP) trades at 9. 2x forward P/E versus 19. 3x for McKesson Corporation — 10. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ANIP: 47. 8% to $124. 00.
08Which pays a better dividend — TXMD or ANIP or TEVA or MCK?
In this comparison, MCK (0.
4% yield) pays a dividend. TXMD, ANIP, TEVA do not pay a meaningful dividend and should not be held primarily for income.
09Is TXMD or ANIP or TEVA or MCK better for a retirement portfolio?
For long-horizon retirement investors, McKesson Corporation (MCK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
04), +348. 1% 10Y return). Both have compounded well over 10 years (MCK: +348. 1%, TEVA: -28. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TXMD and ANIP and TEVA and MCK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TXMD is a small-cap high-growth stock; ANIP is a small-cap high-growth stock; TEVA is a mid-cap quality compounder stock; MCK is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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