Drug Manufacturers - Specialty & Generic
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TXMD vs EVAX vs PGNY vs NEON vs HIMS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Healthcare Information Services
Hardware, Equipment & Parts
Medical - Equipment & Services
TXMD vs EVAX vs PGNY vs NEON vs HIMS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Medical - Healthcare Information Services | Hardware, Equipment & Parts | Medical - Equipment & Services |
| Market Cap | $23M | $26M | $1.57B | $31M | $6.63B |
| Revenue (TTM) | $3M | $8M | $1.29B | $2M | $2.35B |
| Net Income (TTM) | $302K | $-8M | $68M | $8M | $128M |
| Gross Margin | 96.6% | 99.7% | 24.1% | 98.7% | 69.7% |
| Operating Margin | -97.1% | -122.7% | 7.5% | -391.5% | 4.6% |
| Forward P/E | — | — | 16.4x | 3.6x | 51.5x |
| Total Debt | $7M | $8M | $24M | $371K | $1.12B |
| Cash & Equiv. | $5M | $23M | $112M | $25M | $229M |
TXMD vs EVAX vs PGNY vs NEON vs HIMS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| TherapeuticsMD, Inc. (TXMD) | 100 | 2.6 | -97.4% |
| Evaxion Biotech A/S (EVAX) | 100 | 1.2 | -98.8% |
| Progyny, Inc. (PGNY) | 100 | 45.5 | -54.5% |
| Neonode Inc. (NEON) | 100 | 23.1 | -76.9% |
| Hims & Hers Health,… (HIMS) | 100 | 176.1 | +76.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TXMD vs EVAX vs PGNY vs NEON vs HIMS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TXMD ranks third and is worth considering specifically for income & stability.
- Dividend streak 1 yrs, beta 0.51
- Beta 0.51 vs HIMS's 2.40, lower leverage
EVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 125.8%, EPS growth 87.7%
- 125.8% revenue growth vs NEON's -33.7%
- +175.0% vs NEON's -83.7%
PGNY lags the leaders in this set but could rank higher in a more targeted comparison.
NEON carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.
- Lower volatility, beta 0.94, Low D/E 1.5%, current ratio 12.05x
- Beta 0.94, current ratio 12.05x
- Lower P/E (3.6x vs 51.5x)
- 411.9% margin vs EVAX's -102.4%
HIMS is the clearest fit if your priority is long-term compounding.
- 161.9% 10Y total return vs PGNY's 20.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 125.8% revenue growth vs NEON's -33.7% | |
| Value | Lower P/E (3.6x vs 51.5x) | |
| Quality / Margins | 411.9% margin vs EVAX's -102.4% | |
| Stability / Safety | Beta 0.51 vs HIMS's 2.40, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +175.0% vs NEON's -83.7% | |
| Efficiency (ROA) | 37.0% ROA vs EVAX's -29.2%, ROIC -46.0% vs -295.2% |
TXMD vs EVAX vs PGNY vs NEON vs HIMS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
TXMD vs EVAX vs PGNY vs NEON vs HIMS — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
TXMD leads in 3 of 6 categories
PGNY leads 1 • HIMS leads 1 • EVAX leads 0 • NEON leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
TXMD leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
HIMS is the larger business by revenue, generating $2.3B annually — 1138.5x NEON's $2M. NEON is the more profitable business, keeping 4.1% of every revenue dollar as net income compared to EVAX's -102.4%. On growth, TXMD holds the edge at +43.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $3M | $8M | $1.3B | $2M | $2.3B |
| EBITDAEarnings before interest/tax | -$2M | -$4M | $100M | -$8M | $164M |
| Net IncomeAfter-tax profit | $302,000 | -$8M | $68M | $8M | $128M |
| Free Cash FlowCash after capex | $2M | -$7M | $181M | -$10M | $73M |
| Gross MarginGross profit ÷ Revenue | +96.6% | +99.7% | +24.1% | +98.7% | +69.7% |
| Operating MarginEBIT ÷ Revenue | -97.1% | -122.7% | +7.5% | -3.9% | +4.6% |
| Net MarginNet income ÷ Revenue | +10.8% | -102.4% | +5.2% | +4.1% | +5.5% |
| FCF MarginFCF ÷ Revenue | +74.0% | -88.2% | +14.0% | -5.0% | +3.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +43.3% | -81.9% | +1.4% | -20.6% | +28.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +118.9% | +73.8% | +70.6% | -25.9% | -27.3% |
Valuation Metrics
PGNY leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 3.6x trailing earnings, NEON trades at a 93% valuation discount to HIMS's 50.3x P/E. On an enterprise value basis, PGNY's 16.4x EV/EBITDA is more attractive than HIMS's 42.7x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $23M | $26M | $1.6B | $31M | $6.6B |
| Enterprise ValueMkt cap + debt − cash | $25M | $10M | $1.5B | $6M | $7.5B |
| Trailing P/EPrice ÷ TTM EPS | -10.58x | -3.36x | 29.48x | 3.57x | 50.32x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 16.39x | — | 51.51x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 4.40x | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 16.41x | — | 42.68x |
| Price / SalesMarket cap ÷ Revenue | 13.21x | 3.40x | 1.22x | 14.81x | 2.82x |
| Price / BookPrice ÷ Book value/share | 0.85x | 1.53x | 3.32x | 1.24x | 12.25x |
| Price / FCFMarket cap ÷ FCF | 31.78x | — | 8.18x | — | 89.61x |
Profitability & Efficiency
Evenly matched — PGNY and NEON each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
NEON delivers a 43.2% return on equity — every $100 of shareholder capital generates $43 in annual profit, vs $-62 for EVAX. NEON carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to HIMS's 2.07x. On the Piotroski fundamental quality scale (0–9), TXMD scores 6/9 vs HIMS's 4/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +1.1% | -61.6% | +13.3% | +43.2% | +23.7% |
| ROA (TTM)Return on assets | +0.8% | -29.2% | +9.0% | +37.0% | +6.0% |
| ROICReturn on invested capital | -11.4% | -3.0% | +18.1% | -46.0% | +10.7% |
| ROCEReturn on capital employed | -13.6% | -57.4% | +17.4% | -38.9% | +10.9% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 4 | 6 | 5 | 4 |
| Debt / EquityFinancial leverage | 0.26x | 0.44x | 0.05x | 0.02x | 2.07x |
| Net DebtTotal debt minus cash | $2M | -$16M | -$88M | -$25M | $892M |
| Cash & Equiv.Liquid assets | $5M | $23M | $112M | $25M | $229M |
| Total DebtShort + long-term debt | $7M | $8M | $24M | $371,000 | $1.1B |
| Interest CoverageEBIT ÷ Interest expense | -194.43x | -10.54x | — | — | — |
Total Returns (Dividends Reinvested)
HIMS leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in HIMS five years ago would be worth $23,764 today (with dividends reinvested), compared to $123 for EVAX. Over the past 12 months, EVAX leads with a +175.0% total return vs NEON's -83.7%. The 3-year compound annual growth rate (CAGR) favors HIMS at 29.4% vs EVAX's -62.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +21.8% | -13.6% | -25.6% | 0.0% | -23.2% |
| 1-Year ReturnPast 12 months | +45.7% | +175.0% | -18.2% | -83.7% | -51.0% |
| 3-Year ReturnCumulative with dividends | -48.2% | -94.5% | -45.0% | -74.8% | +116.6% |
| 5-Year ReturnCumulative with dividends | -96.3% | -98.8% | -62.9% | -78.3% | +137.6% |
| 10-Year ReturnCumulative with dividends | -99.5% | -99.2% | +20.2% | -91.1% | +161.9% |
| CAGR (3Y)Annualised 3-year return | -19.7% | -62.0% | -18.1% | -36.9% | +29.4% |
Risk & Volatility
TXMD leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
TXMD is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than HIMS's 2.40 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TXMD currently trades 68.1% from its 52-week high vs NEON's 6.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 1.29x | 0.71x | 0.94x | 2.40x |
| 52-Week HighHighest price in past year | $2.95 | $12.15 | $28.75 | $29.90 | $70.43 |
| 52-Week LowLowest price in past year | $0.98 | $1.43 | $16.10 | $1.27 | $13.74 |
| % of 52W HighCurrent price vs 52-week peak | +68.1% | +33.5% | +66.6% | +6.1% | +36.4% |
| RSI (14)Momentum oscillator 0–100 | 43.3 | 56.5 | 57.6 | 62.4 | 54.5 |
| Avg Volume (50D)Average daily shares traded | 21K | 32K | 1.5M | 103K | 34.9M |
Analyst Outlook
TXMD leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: PGNY as "Buy", HIMS as "Hold". Consensus price targets imply 60.8% upside for PGNY (target: $31) vs 15.6% for HIMS (target: $30).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | — | Buy | — | Hold |
| Price TargetConsensus 12-month target | — | — | $30.80 | — | $29.67 |
| # AnalystsCovering analysts | — | — | 20 | — | 19 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | 0 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +5.2% | 0.0% | +1.4% |
TXMD leads in 3 of 6 categories (Income & Cash Flow, Risk & Volatility). PGNY leads in 1 (Valuation Metrics). 1 tied.
TXMD vs EVAX vs PGNY vs NEON vs HIMS: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TXMD or EVAX or PGNY or NEON or HIMS a better buy right now?
For growth investors, Evaxion Biotech A/S (EVAX) is the stronger pick with 125.
8% revenue growth year-over-year, versus -33. 7% for Neonode Inc. (NEON). Neonode Inc. (NEON) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Progyny, Inc. (PGNY) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TXMD or EVAX or PGNY or NEON or HIMS?
On trailing P/E, Neonode Inc.
(NEON) is the cheapest at 3. 6x versus Hims & Hers Health, Inc. at 50. 3x. On forward P/E, Progyny, Inc. is actually cheaper at 16. 4x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — TXMD or EVAX or PGNY or NEON or HIMS?
Over the past 5 years, Hims & Hers Health, Inc.
(HIMS) delivered a total return of +137. 6%, compared to -98. 8% for Evaxion Biotech A/S (EVAX). Over 10 years, the gap is even starker: HIMS returned +161. 9% versus TXMD's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TXMD or EVAX or PGNY or NEON or HIMS?
By beta (market sensitivity over 5 years), TherapeuticsMD, Inc.
(TXMD) is the lower-risk stock at 0. 51β versus Hims & Hers Health, Inc. 's 2. 40β — meaning HIMS is approximately 368% more volatile than TXMD relative to the S&P 500. On balance sheet safety, Neonode Inc. (NEON) carries a lower debt/equity ratio of 2% versus 2% for Hims & Hers Health, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — TXMD or EVAX or PGNY or NEON or HIMS?
By revenue growth (latest reported year), Evaxion Biotech A/S (EVAX) is pulling ahead at 125.
8% versus -33. 7% for Neonode Inc. (NEON). On earnings-per-share growth, the picture is similar: Neonode Inc. grew EPS 224. 4% year-over-year, compared to -3. 8% for Hims & Hers Health, Inc.. Over a 3-year CAGR, HIMS leads at 64. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TXMD or EVAX or PGNY or NEON or HIMS?
Neonode Inc.
(NEON) is the more profitable company, earning 411. 9% net margin versus -123. 9% for TherapeuticsMD, Inc. — meaning it keeps 411. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PGNY leads at 6. 6% versus -391. 5% for NEON. At the gross margin level — before operating expenses — TXMD leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TXMD or EVAX or PGNY or NEON or HIMS more undervalued right now?
On forward earnings alone, Progyny, Inc.
(PGNY) trades at 16. 4x forward P/E versus 51. 5x for Hims & Hers Health, Inc. — 35. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PGNY: 60. 8% to $30. 80.
08Which pays a better dividend — TXMD or EVAX or PGNY or NEON or HIMS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is TXMD or EVAX or PGNY or NEON or HIMS better for a retirement portfolio?
For long-horizon retirement investors, TherapeuticsMD, Inc.
(TXMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 51)). Hims & Hers Health, Inc. (HIMS) carries a higher beta of 2. 40 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TXMD: -99. 5%, HIMS: +161. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TXMD and EVAX and PGNY and NEON and HIMS?
These companies operate in different sectors (TXMD (Healthcare) and EVAX (Healthcare) and PGNY (Healthcare) and NEON (Technology) and HIMS (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: TXMD is a small-cap high-growth stock; EVAX is a small-cap high-growth stock; PGNY is a small-cap quality compounder stock; NEON is a small-cap deep-value stock; HIMS is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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