Drug Manufacturers - Specialty & Generic
Compare Stocks
5 / 10Stock Comparison
TXMD vs PGNY vs DARE vs ANIP vs EVAX
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Healthcare Information Services
Biotechnology
Drug Manufacturers - Specialty & Generic
Biotechnology
TXMD vs PGNY vs DARE vs ANIP vs EVAX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Medical - Healthcare Information Services | Biotechnology | Drug Manufacturers - Specialty & Generic | Biotechnology |
| Market Cap | $23M | $1.57B | $25M | $1.78B | $26M |
| Revenue (TTM) | $3M | $1.29B | $-57K | $883M | $8M |
| Net Income (TTM) | $302K | $68M | $-17M | $78M | $-8M |
| Gross Margin | 96.6% | 24.1% | -1461.1% | 69.1% | 99.7% |
| Operating Margin | -97.1% | 7.5% | -2396.9% | 12.6% | -122.7% |
| Forward P/E | — | 16.4x | — | 9.2x | — |
| Total Debt | $7M | $24M | $1M | $325M | $8M |
| Cash & Equiv. | $5M | $112M | $16M | $286M | $23M |
TXMD vs PGNY vs DARE vs ANIP vs EVAX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| TherapeuticsMD, Inc. (TXMD) | 100 | 2.6 | -97.4% |
| Progyny, Inc. (PGNY) | 100 | 45.5 | -54.5% |
| Daré Bioscience, In… (DARE) | 100 | 13.0 | -87.0% |
| ANI Pharmaceuticals… (ANIP) | 100 | 288.4 | +188.4% |
| Evaxion Biotech A/S (EVAX) | 100 | 1.2 | -98.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TXMD vs PGNY vs DARE vs ANIP vs EVAX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TXMD ranks third and is worth considering specifically for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.51
- Lower volatility, beta 0.51, Low D/E 26.2%, current ratio 1.92x
- 10.8% margin vs DARE's -414.3%
PGNY is the clearest fit if your priority is efficiency.
- 9.0% ROA vs DARE's -56.8%
DARE is the clearest fit if your priority is defensive.
- Beta 0.48, current ratio 0.85x
- Beta 0.48 vs EVAX's 1.29
ANIP has the current edge in this matchup, primarily because of its strength in growth exposure and long-term compounding.
- Rev growth 43.8%, EPS growth 419.2%, 3Y rev CAGR 40.8%
- 84.7% 10Y total return vs PGNY's 20.2%
- Better valuation composite
- 0.1% yield; the other 4 pay no meaningful dividend
EVAX is the #2 pick in this set and the best alternative if growth and momentum is your priority.
- 125.8% revenue growth vs DARE's -99.7%
- +175.0% vs PGNY's -18.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 125.8% revenue growth vs DARE's -99.7% | |
| Value | Better valuation composite | |
| Quality / Margins | 10.8% margin vs DARE's -414.3% | |
| Stability / Safety | Beta 0.48 vs EVAX's 1.29 | |
| Dividends | 0.1% yield; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +175.0% vs PGNY's -18.2% | |
| Efficiency (ROA) | 9.0% ROA vs DARE's -56.8% |
TXMD vs PGNY vs DARE vs ANIP vs EVAX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
TXMD vs PGNY vs DARE vs ANIP vs EVAX — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PGNY leads in 1 of 6 categories
ANIP leads 1 • TXMD leads 1 • DARE leads 0 • EVAX leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PGNY and DARE operate at a comparable scale, with $1.3B and -$57,130 in trailing revenue. TXMD is the more profitable business, keeping 10.8% of every revenue dollar as net income compared to DARE's -414.3%. On growth, TXMD holds the edge at +43.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $3M | $1.3B | -$57,130 | $883M | $8M |
| EBITDAEarnings before interest/tax | -$2M | $100M | -$16M | $203M | -$4M |
| Net IncomeAfter-tax profit | $302,000 | $68M | -$17M | $78M | -$8M |
| Free Cash FlowCash after capex | $2M | $181M | -$7M | $128M | -$7M |
| Gross MarginGross profit ÷ Revenue | +96.6% | +24.1% | -1461.1% | +69.1% | +99.7% |
| Operating MarginEBIT ÷ Revenue | -97.1% | +7.5% | -2396.9% | +12.6% | -122.7% |
| Net MarginNet income ÷ Revenue | +10.8% | +5.2% | -414.3% | +8.9% | -102.4% |
| FCF MarginFCF ÷ Revenue | +74.0% | +14.0% | +492.8% | +14.5% | -88.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +43.3% | +1.4% | -94.6% | +29.6% | -81.9% |
| EPS Growth (YoY)Latest quarter vs prior year | +118.9% | +70.6% | +49.2% | +3.1% | +73.8% |
Valuation Metrics
Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.
Valuation Metrics
At 25.3x trailing earnings, ANIP trades at a 14% valuation discount to PGNY's 29.5x P/E. On an enterprise value basis, ANIP's 9.0x EV/EBITDA is more attractive than PGNY's 16.4x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $23M | $1.6B | $25M | $1.8B | $26M |
| Enterprise ValueMkt cap + debt − cash | $25M | $1.5B | $11M | $1.8B | $10M |
| Trailing P/EPrice ÷ TTM EPS | -10.58x | 29.48x | -6.06x | 25.27x | -3.36x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 16.39x | — | 9.25x | — |
| PEG RatioP/E ÷ EPS growth rate | — | 4.40x | — | — | — |
| EV / EBITDAEnterprise value multiple | — | 16.41x | — | 8.99x | — |
| Price / SalesMarket cap ÷ Revenue | 13.21x | 1.22x | 2587.71x | 2.02x | 3.40x |
| Price / BookPrice ÷ Book value/share | 0.85x | 3.32x | — | 3.29x | 1.53x |
| Price / FCFMarket cap ÷ FCF | 31.78x | 8.18x | 5.25x | 9.62x | — |
Profitability & Efficiency
PGNY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
ANIP delivers a 14.5% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-6 for DARE. PGNY carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to ANIP's 0.60x. On the Piotroski fundamental quality scale (0–9), TXMD scores 6/9 vs EVAX's 4/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +1.1% | +13.3% | -6.1% | +14.5% | -61.6% |
| ROA (TTM)Return on assets | +0.8% | +9.0% | -56.8% | +5.4% | -29.2% |
| ROICReturn on invested capital | -11.4% | +18.1% | — | +11.2% | -3.0% |
| ROCEReturn on capital employed | -13.6% | +17.4% | -36.2% | +9.9% | -57.4% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 6 | 4 | 6 | 4 |
| Debt / EquityFinancial leverage | 0.26x | 0.05x | — | 0.60x | 0.44x |
| Net DebtTotal debt minus cash | $2M | -$88M | -$14M | $40M | -$16M |
| Cash & Equiv.Liquid assets | $5M | $112M | $16M | $286M | $23M |
| Total DebtShort + long-term debt | $7M | $24M | $1M | $325M | $8M |
| Interest CoverageEBIT ÷ Interest expense | -194.43x | — | -35.60x | 1.82x | -10.54x |
Total Returns (Dividends Reinvested)
ANIP leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ANIP five years ago would be worth $21,738 today (with dividends reinvested), compared to $123 for EVAX. Over the past 12 months, EVAX leads with a +175.0% total return vs PGNY's -18.2%. The 3-year compound annual growth rate (CAGR) favors ANIP at 25.4% vs EVAX's -62.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +21.8% | -25.6% | +49.2% | +7.0% | -13.6% |
| 1-Year ReturnPast 12 months | +45.7% | -18.2% | +0.7% | +18.5% | +175.0% |
| 3-Year ReturnCumulative with dividends | -48.2% | -45.0% | -75.8% | +97.1% | -94.5% |
| 5-Year ReturnCumulative with dividends | -96.3% | -62.9% | -82.4% | +117.4% | -98.8% |
| 10-Year ReturnCumulative with dividends | -99.5% | +20.2% | -99.0% | +84.7% | -99.2% |
| CAGR (3Y)Annualised 3-year return | -19.7% | -18.1% | -37.6% | +25.4% | -62.0% |
Risk & Volatility
Evenly matched — DARE and ANIP each lead in 1 of 2 comparable metrics.
Risk & Volatility
DARE is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than EVAX's 1.29 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ANIP currently trades 84.3% from its 52-week high vs DARE's 31.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 0.71x | 0.48x | 0.63x | 1.29x |
| 52-Week HighHighest price in past year | $2.95 | $28.75 | $9.19 | $99.50 | $12.15 |
| 52-Week LowLowest price in past year | $0.98 | $16.10 | $1.27 | $56.71 | $1.43 |
| % of 52W HighCurrent price vs 52-week peak | +68.1% | +66.6% | +31.7% | +84.3% | +33.5% |
| RSI (14)Momentum oscillator 0–100 | 43.3 | 57.6 | 70.2 | 64.4 | 56.5 |
| Avg Volume (50D)Average daily shares traded | 21K | 1.5M | 581K | 328K | 32K |
Analyst Outlook
TXMD leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: PGNY as "Buy", ANIP as "Buy". Consensus price targets imply 60.8% upside for PGNY (target: $31) vs 47.8% for ANIP (target: $124).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | — | Buy | — |
| Price TargetConsensus 12-month target | — | $30.80 | — | $124.00 | — |
| # AnalystsCovering analysts | — | 20 | — | 10 | — |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.1% | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | 0 | — |
| Dividend / ShareAnnual DPS | — | — | — | $0.05 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.2% | 0.0% | +0.7% | 0.0% |
PGNY leads in 1 of 6 categories (Profitability & Efficiency). ANIP leads in 1 (Total Returns). 3 tied.
TXMD vs PGNY vs DARE vs ANIP vs EVAX: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TXMD or PGNY or DARE or ANIP or EVAX a better buy right now?
For growth investors, Evaxion Biotech A/S (EVAX) is the stronger pick with 125.
8% revenue growth year-over-year, versus -99. 7% for Daré Bioscience, Inc. (DARE). ANI Pharmaceuticals, Inc. (ANIP) offers the better valuation at 25. 3x trailing P/E (9. 2x forward), making it the more compelling value choice. Analysts rate Progyny, Inc. (PGNY) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TXMD or PGNY or DARE or ANIP or EVAX?
On trailing P/E, ANI Pharmaceuticals, Inc.
(ANIP) is the cheapest at 25. 3x versus Progyny, Inc. at 29. 5x. On forward P/E, ANI Pharmaceuticals, Inc. is actually cheaper at 9. 2x.
03Which is the better long-term investment — TXMD or PGNY or DARE or ANIP or EVAX?
Over the past 5 years, ANI Pharmaceuticals, Inc.
(ANIP) delivered a total return of +117. 4%, compared to -98. 8% for Evaxion Biotech A/S (EVAX). Over 10 years, the gap is even starker: ANIP returned +84. 7% versus TXMD's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TXMD or PGNY or DARE or ANIP or EVAX?
By beta (market sensitivity over 5 years), Daré Bioscience, Inc.
(DARE) is the lower-risk stock at 0. 48β versus Evaxion Biotech A/S's 1. 29β — meaning EVAX is approximately 168% more volatile than DARE relative to the S&P 500. On balance sheet safety, Progyny, Inc. (PGNY) carries a lower debt/equity ratio of 5% versus 60% for ANI Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — TXMD or PGNY or DARE or ANIP or EVAX?
By revenue growth (latest reported year), Evaxion Biotech A/S (EVAX) is pulling ahead at 125.
8% versus -99. 7% for Daré Bioscience, Inc. (DARE). On earnings-per-share growth, the picture is similar: ANI Pharmaceuticals, Inc. grew EPS 419. 2% year-over-year, compared to 14. 0% for Progyny, Inc.. Over a 3-year CAGR, ANIP leads at 40. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TXMD or PGNY or DARE or ANIP or EVAX?
ANI Pharmaceuticals, Inc.
(ANIP) is the more profitable company, earning 8. 9% net margin versus -414. 3% for Daré Bioscience, Inc. — meaning it keeps 8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ANIP leads at 12. 6% versus -2396. 9% for DARE. At the gross margin level — before operating expenses — TXMD leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TXMD or PGNY or DARE or ANIP or EVAX more undervalued right now?
On forward earnings alone, ANI Pharmaceuticals, Inc.
(ANIP) trades at 9. 2x forward P/E versus 16. 4x for Progyny, Inc. — 7. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PGNY: 60. 8% to $30. 80.
08Which pays a better dividend — TXMD or PGNY or DARE or ANIP or EVAX?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is TXMD or PGNY or DARE or ANIP or EVAX better for a retirement portfolio?
For long-horizon retirement investors, Daré Bioscience, Inc.
(DARE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48)). Both have compounded well over 10 years (DARE: -99. 0%, EVAX: -99. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TXMD and PGNY and DARE and ANIP and EVAX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TXMD is a small-cap high-growth stock; PGNY is a small-cap quality compounder stock; DARE is a small-cap quality compounder stock; ANIP is a small-cap high-growth stock; EVAX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.