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Stock Comparison

TXMD vs PGNY vs DARE vs ANIP vs EVAX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TXMD
TherapeuticsMD, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$23M
5Y Perf.-97.4%
PGNY
Progyny, Inc.

Medical - Healthcare Information Services

HealthcareNASDAQ • US
Market Cap$1.57B
5Y Perf.-54.5%
DARE
Daré Bioscience, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$25M
5Y Perf.-87.0%
ANIP
ANI Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.78B
5Y Perf.+188.4%
EVAX
Evaxion Biotech A/S

Biotechnology

HealthcareNASDAQ • DK
Market Cap$26M
5Y Perf.-98.8%

TXMD vs PGNY vs DARE vs ANIP vs EVAX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TXMD logoTXMD
PGNY logoPGNY
DARE logoDARE
ANIP logoANIP
EVAX logoEVAX
IndustryDrug Manufacturers - Specialty & GenericMedical - Healthcare Information ServicesBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnology
Market Cap$23M$1.57B$25M$1.78B$26M
Revenue (TTM)$3M$1.29B$-57K$883M$8M
Net Income (TTM)$302K$68M$-17M$78M$-8M
Gross Margin96.6%24.1%-1461.1%69.1%99.7%
Operating Margin-97.1%7.5%-2396.9%12.6%-122.7%
Forward P/E16.4x9.2x
Total Debt$7M$24M$1M$325M$8M
Cash & Equiv.$5M$112M$16M$286M$23M

TXMD vs PGNY vs DARE vs ANIP vs EVAXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TXMD
PGNY
DARE
ANIP
EVAX
StockFeb 21May 26Return
TherapeuticsMD, Inc. (TXMD)1002.6-97.4%
Progyny, Inc. (PGNY)10045.5-54.5%
Daré Bioscience, In… (DARE)10013.0-87.0%
ANI Pharmaceuticals… (ANIP)100288.4+188.4%
Evaxion Biotech A/S (EVAX)1001.2-98.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: TXMD vs PGNY vs DARE vs ANIP vs EVAX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ANIP and EVAX are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Evaxion Biotech A/S is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. TXMD, PGNY, and DARE also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TXMD
TherapeuticsMD, Inc.
The Income Pick

TXMD ranks third and is worth considering specifically for income & stability and sleep-well-at-night.

  • Dividend streak 1 yrs, beta 0.51
  • Lower volatility, beta 0.51, Low D/E 26.2%, current ratio 1.92x
  • 10.8% margin vs DARE's -414.3%
Best for: income & stability and sleep-well-at-night
PGNY
Progyny, Inc.
The Niche Pick

PGNY is the clearest fit if your priority is efficiency.

  • 9.0% ROA vs DARE's -56.8%
Best for: efficiency
DARE
Daré Bioscience, Inc.
The Defensive Pick

DARE is the clearest fit if your priority is defensive.

  • Beta 0.48, current ratio 0.85x
  • Beta 0.48 vs EVAX's 1.29
Best for: defensive
ANIP
ANI Pharmaceuticals, Inc.
The Growth Play

ANIP has the current edge in this matchup, primarily because of its strength in growth exposure and long-term compounding.

  • Rev growth 43.8%, EPS growth 419.2%, 3Y rev CAGR 40.8%
  • 84.7% 10Y total return vs PGNY's 20.2%
  • Better valuation composite
  • 0.1% yield; the other 4 pay no meaningful dividend
Best for: growth exposure and long-term compounding
EVAX
Evaxion Biotech A/S
The Growth Leader

EVAX is the #2 pick in this set and the best alternative if growth and momentum is your priority.

  • 125.8% revenue growth vs DARE's -99.7%
  • +175.0% vs PGNY's -18.2%
Best for: growth and momentum
See the full category breakdown
CategoryWinnerWhy
GrowthEVAX logoEVAX125.8% revenue growth vs DARE's -99.7%
ValueANIP logoANIPBetter valuation composite
Quality / MarginsTXMD logoTXMD10.8% margin vs DARE's -414.3%
Stability / SafetyDARE logoDAREBeta 0.48 vs EVAX's 1.29
DividendsANIP logoANIP0.1% yield; the other 4 pay no meaningful dividend
Momentum (1Y)EVAX logoEVAX+175.0% vs PGNY's -18.2%
Efficiency (ROA)PGNY logoPGNY9.0% ROA vs DARE's -56.8%

TXMD vs PGNY vs DARE vs ANIP vs EVAX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TXMDTherapeuticsMD, Inc.
FY 2023
License
100.0%$1M
PGNYProgyny, Inc.
FY 2025
Fertility benefit services revenue
64.5%$831M
Pharmacy benefit services revenue
35.5%$458M
DAREDaré Bioscience, Inc.
FY 2024
License And Collaboration Revenues
99.8%$11M
Royalty Revenue
0.2%$18,000
ANIPANI Pharmaceuticals, Inc.
FY 2024
Total Sales of Generics and Other
52.1%$320M
Sales of rare disease pharmaceutical products
37.4%$230M
Sales of Established Brands
10.5%$65M
EVAXEvaxion Biotech A/S

Segment breakdown not available.

TXMD vs PGNY vs DARE vs ANIP vs EVAX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTXMDLAGGINGEVAX

Income & Cash Flow (Last 12 Months)

Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.

PGNY and DARE operate at a comparable scale, with $1.3B and -$57,130 in trailing revenue. TXMD is the more profitable business, keeping 10.8% of every revenue dollar as net income compared to DARE's -414.3%. On growth, TXMD holds the edge at +43.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
RevenueTrailing 12 months$3M$1.3B-$57,130$883M$8M
EBITDAEarnings before interest/tax-$2M$100M-$16M$203M-$4M
Net IncomeAfter-tax profit$302,000$68M-$17M$78M-$8M
Free Cash FlowCash after capex$2M$181M-$7M$128M-$7M
Gross MarginGross profit ÷ Revenue+96.6%+24.1%-1461.1%+69.1%+99.7%
Operating MarginEBIT ÷ Revenue-97.1%+7.5%-2396.9%+12.6%-122.7%
Net MarginNet income ÷ Revenue+10.8%+5.2%-414.3%+8.9%-102.4%
FCF MarginFCF ÷ Revenue+74.0%+14.0%+492.8%+14.5%-88.2%
Rev. Growth (YoY)Latest quarter vs prior year+43.3%+1.4%-94.6%+29.6%-81.9%
EPS Growth (YoY)Latest quarter vs prior year+118.9%+70.6%+49.2%+3.1%+73.8%
Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.

Valuation Metrics

Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.

At 25.3x trailing earnings, ANIP trades at a 14% valuation discount to PGNY's 29.5x P/E. On an enterprise value basis, ANIP's 9.0x EV/EBITDA is more attractive than PGNY's 16.4x.

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
Market CapShares × price$23M$1.6B$25M$1.8B$26M
Enterprise ValueMkt cap + debt − cash$25M$1.5B$11M$1.8B$10M
Trailing P/EPrice ÷ TTM EPS-10.58x29.48x-6.06x25.27x-3.36x
Forward P/EPrice ÷ next-FY EPS est.16.39x9.25x
PEG RatioP/E ÷ EPS growth rate4.40x
EV / EBITDAEnterprise value multiple16.41x8.99x
Price / SalesMarket cap ÷ Revenue13.21x1.22x2587.71x2.02x3.40x
Price / BookPrice ÷ Book value/share0.85x3.32x3.29x1.53x
Price / FCFMarket cap ÷ FCF31.78x8.18x5.25x9.62x
Evenly matched — TXMD and ANIP each lead in 2 of 6 comparable metrics.

Profitability & Efficiency

PGNY leads this category, winning 6 of 9 comparable metrics.

ANIP delivers a 14.5% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-6 for DARE. PGNY carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to ANIP's 0.60x. On the Piotroski fundamental quality scale (0–9), TXMD scores 6/9 vs EVAX's 4/9, reflecting solid financial health.

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
ROE (TTM)Return on equity+1.1%+13.3%-6.1%+14.5%-61.6%
ROA (TTM)Return on assets+0.8%+9.0%-56.8%+5.4%-29.2%
ROICReturn on invested capital-11.4%+18.1%+11.2%-3.0%
ROCEReturn on capital employed-13.6%+17.4%-36.2%+9.9%-57.4%
Piotroski ScoreFundamental quality 0–966464
Debt / EquityFinancial leverage0.26x0.05x0.60x0.44x
Net DebtTotal debt minus cash$2M-$88M-$14M$40M-$16M
Cash & Equiv.Liquid assets$5M$112M$16M$286M$23M
Total DebtShort + long-term debt$7M$24M$1M$325M$8M
Interest CoverageEBIT ÷ Interest expense-194.43x-35.60x1.82x-10.54x
PGNY leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ANIP leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ANIP five years ago would be worth $21,738 today (with dividends reinvested), compared to $123 for EVAX. Over the past 12 months, EVAX leads with a +175.0% total return vs PGNY's -18.2%. The 3-year compound annual growth rate (CAGR) favors ANIP at 25.4% vs EVAX's -62.0% — a key indicator of consistent wealth creation.

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
YTD ReturnYear-to-date+21.8%-25.6%+49.2%+7.0%-13.6%
1-Year ReturnPast 12 months+45.7%-18.2%+0.7%+18.5%+175.0%
3-Year ReturnCumulative with dividends-48.2%-45.0%-75.8%+97.1%-94.5%
5-Year ReturnCumulative with dividends-96.3%-62.9%-82.4%+117.4%-98.8%
10-Year ReturnCumulative with dividends-99.5%+20.2%-99.0%+84.7%-99.2%
CAGR (3Y)Annualised 3-year return-19.7%-18.1%-37.6%+25.4%-62.0%
ANIP leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DARE and ANIP each lead in 1 of 2 comparable metrics.

DARE is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than EVAX's 1.29 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ANIP currently trades 84.3% from its 52-week high vs DARE's 31.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
Beta (5Y)Sensitivity to S&P 5000.51x0.71x0.48x0.63x1.29x
52-Week HighHighest price in past year$2.95$28.75$9.19$99.50$12.15
52-Week LowLowest price in past year$0.98$16.10$1.27$56.71$1.43
% of 52W HighCurrent price vs 52-week peak+68.1%+66.6%+31.7%+84.3%+33.5%
RSI (14)Momentum oscillator 0–10043.357.670.264.456.5
Avg Volume (50D)Average daily shares traded21K1.5M581K328K32K
Evenly matched — DARE and ANIP each lead in 1 of 2 comparable metrics.

Analyst Outlook

TXMD leads this category, winning 1 of 1 comparable metric.

Analyst consensus: PGNY as "Buy", ANIP as "Buy". Consensus price targets imply 60.8% upside for PGNY (target: $31) vs 47.8% for ANIP (target: $124).

MetricTXMD logoTXMDTherapeuticsMD, I…PGNY logoPGNYProgyny, Inc.DARE logoDAREDaré Bioscience, …ANIP logoANIPANI Pharmaceutica…EVAX logoEVAXEvaxion Biotech A…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$30.80$124.00
# AnalystsCovering analysts2010
Dividend YieldAnnual dividend ÷ price+0.1%
Dividend StreakConsecutive years of raises10
Dividend / ShareAnnual DPS$0.05
Buyback YieldShare repurchases ÷ mkt cap0.0%+5.2%0.0%+0.7%0.0%
TXMD leads this category, winning 1 of 1 comparable metric.
Key Takeaway

PGNY leads in 1 of 6 categories (Profitability & Efficiency). ANIP leads in 1 (Total Returns). 3 tied.

Best OverallTherapeuticsMD, Inc. (TXMD)Leads 1 of 6 categories
Loading custom metrics...

TXMD vs PGNY vs DARE vs ANIP vs EVAX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TXMD or PGNY or DARE or ANIP or EVAX a better buy right now?

For growth investors, Evaxion Biotech A/S (EVAX) is the stronger pick with 125.

8% revenue growth year-over-year, versus -99. 7% for Daré Bioscience, Inc. (DARE). ANI Pharmaceuticals, Inc. (ANIP) offers the better valuation at 25. 3x trailing P/E (9. 2x forward), making it the more compelling value choice. Analysts rate Progyny, Inc. (PGNY) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TXMD or PGNY or DARE or ANIP or EVAX?

On trailing P/E, ANI Pharmaceuticals, Inc.

(ANIP) is the cheapest at 25. 3x versus Progyny, Inc. at 29. 5x. On forward P/E, ANI Pharmaceuticals, Inc. is actually cheaper at 9. 2x.

03

Which is the better long-term investment — TXMD or PGNY or DARE or ANIP or EVAX?

Over the past 5 years, ANI Pharmaceuticals, Inc.

(ANIP) delivered a total return of +117. 4%, compared to -98. 8% for Evaxion Biotech A/S (EVAX). Over 10 years, the gap is even starker: ANIP returned +84. 7% versus TXMD's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TXMD or PGNY or DARE or ANIP or EVAX?

By beta (market sensitivity over 5 years), Daré Bioscience, Inc.

(DARE) is the lower-risk stock at 0. 48β versus Evaxion Biotech A/S's 1. 29β — meaning EVAX is approximately 168% more volatile than DARE relative to the S&P 500. On balance sheet safety, Progyny, Inc. (PGNY) carries a lower debt/equity ratio of 5% versus 60% for ANI Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TXMD or PGNY or DARE or ANIP or EVAX?

By revenue growth (latest reported year), Evaxion Biotech A/S (EVAX) is pulling ahead at 125.

8% versus -99. 7% for Daré Bioscience, Inc. (DARE). On earnings-per-share growth, the picture is similar: ANI Pharmaceuticals, Inc. grew EPS 419. 2% year-over-year, compared to 14. 0% for Progyny, Inc.. Over a 3-year CAGR, ANIP leads at 40. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TXMD or PGNY or DARE or ANIP or EVAX?

ANI Pharmaceuticals, Inc.

(ANIP) is the more profitable company, earning 8. 9% net margin versus -414. 3% for Daré Bioscience, Inc. — meaning it keeps 8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ANIP leads at 12. 6% versus -2396. 9% for DARE. At the gross margin level — before operating expenses — TXMD leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TXMD or PGNY or DARE or ANIP or EVAX more undervalued right now?

On forward earnings alone, ANI Pharmaceuticals, Inc.

(ANIP) trades at 9. 2x forward P/E versus 16. 4x for Progyny, Inc. — 7. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PGNY: 60. 8% to $30. 80.

08

Which pays a better dividend — TXMD or PGNY or DARE or ANIP or EVAX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is TXMD or PGNY or DARE or ANIP or EVAX better for a retirement portfolio?

For long-horizon retirement investors, Daré Bioscience, Inc.

(DARE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48)). Both have compounded well over 10 years (DARE: -99. 0%, EVAX: -99. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TXMD and PGNY and DARE and ANIP and EVAX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TXMD is a small-cap high-growth stock; PGNY is a small-cap quality compounder stock; DARE is a small-cap quality compounder stock; ANIP is a small-cap high-growth stock; EVAX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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EVAX

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 59%
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Beat Both

Find stocks that outperform TXMD and PGNY and DARE and ANIP and EVAX on the metrics below

Revenue Growth>
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(TXMD: 43.3% · PGNY: 1.4%)
Net Margin>
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(TXMD: 10.8% · PGNY: 5.2%)

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