Biotechnology
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VIR vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
VIR vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $1.66B | $74.89B |
| Revenue (TTM) | $69M | $14.92B |
| Net Income (TTM) | $-438M | $4.42B |
| Gross Margin | 100.0% | 84.5% |
| Operating Margin | -6.8% | 24.3% |
| Forward P/E | — | 15.6x |
| Total Debt | $187M | $2.71B |
| Cash & Equiv. | $234M | $3.12B |
VIR vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Vir Biotechnology, … (VIR) | 100 | 30.1 | -69.9% |
| Regeneron Pharmaceu… (REGN) | 100 | 117.6 | +17.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: VIR vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
VIR is the clearest fit if your priority is momentum.
- +82.8% vs REGN's +29.7%
REGN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 0.81, yield 0.5%
- Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
- 96.0% 10Y total return vs VIR's -26.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 1.0% revenue growth vs VIR's -7.6% | |
| Quality / Margins | 29.6% margin vs VIR's -6.4% | |
| Stability / Safety | Beta 0.81 vs VIR's 2.05, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other pay no meaningful dividend | |
| Momentum (1Y) | +82.8% vs REGN's +29.7% | |
| Efficiency (ROA) | 11.1% ROA vs VIR's -38.7%, ROIC 8.9% vs -40.3% |
VIR vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
VIR vs REGN — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
Evenly matched — VIR and REGN each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN is the larger business by revenue, generating $14.9B annually — 217.6x VIR's $69M. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to VIR's -6.4%. On growth, VIR holds the edge at +4.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $69M | $14.9B |
| EBITDAEarnings before interest/tax | -$456M | $4.2B |
| Net IncomeAfter-tax profit | -$438M | $4.4B |
| Free Cash FlowCash after capex | -$392M | $4.2B |
| Gross MarginGross profit ÷ Revenue | +100.0% | +84.5% |
| Operating MarginEBIT ÷ Revenue | -6.8% | +24.3% |
| Net MarginNet income ÷ Revenue | -6.4% | +29.6% |
| FCF MarginFCF ÷ Revenue | -5.7% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | +4.2% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +59.2% | -7.2% |
Valuation Metrics
VIR leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $1.7B | $74.9B |
| Enterprise ValueMkt cap + debt − cash | $1.6B | $74.5B |
| Trailing P/EPrice ÷ TTM EPS | -3.26x | 17.38x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.60x |
| PEG RatioP/E ÷ EPS growth rate | — | 2.75x |
| EV / EBITDAEnterprise value multiple | — | 18.07x |
| Price / SalesMarket cap ÷ Revenue | 24.20x | 5.22x |
| Price / BookPrice ÷ Book value/share | 1.86x | 2.50x |
| Price / FCFMarket cap ÷ FCF | — | 18.35x |
Profitability & Efficiency
REGN leads this category, winning 7 of 8 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-49 for VIR. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to VIR's 0.24x. On the Piotroski fundamental quality scale (0–9), REGN scores 5/9 vs VIR's 3/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -49.3% | +14.3% |
| ROA (TTM)Return on assets | -38.7% | +11.1% |
| ROICReturn on invested capital | -40.3% | +8.9% |
| ROCEReturn on capital employed | -42.8% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 |
| Debt / EquityFinancial leverage | 0.24x | 0.09x |
| Net DebtTotal debt minus cash | -$47M | -$412M |
| Cash & Equiv.Liquid assets | $234M | $3.1B |
| Total DebtShort + long-term debt | $187M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | 108.44x |
Total Returns (Dividends Reinvested)
REGN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in REGN five years ago would be worth $14,543 today (with dividends reinvested), compared to $2,473 for VIR. Over the past 12 months, VIR leads with a +82.8% total return vs REGN's +29.7%. The 3-year compound annual growth rate (CAGR) favors REGN at -1.2% vs VIR's -24.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +73.2% | -7.0% |
| 1-Year ReturnPast 12 months | +82.8% | +29.7% |
| 3-Year ReturnCumulative with dividends | -57.4% | -3.6% |
| 5-Year ReturnCumulative with dividends | -75.3% | +45.4% |
| 10-Year ReturnCumulative with dividends | -26.6% | +96.0% |
| CAGR (3Y)Annualised 3-year return | -24.7% | -1.2% |
Risk & Volatility
Evenly matched — VIR and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than VIR's 2.05 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.05x | 0.81x |
| 52-Week HighHighest price in past year | $11.66 | $821.11 |
| 52-Week LowLowest price in past year | $4.16 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +88.3% | +87.8% |
| RSI (14)Momentum oscillator 0–100 | 51.0 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 2.9M | 634K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates VIR as "Buy" and REGN as "Buy". Consensus price targets imply 106.9% upside for VIR (target: $21) vs 20.1% for REGN (target: $866). REGN is the only dividend payer here at 0.47% yield — a key consideration for income-focused portfolios.
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $21.29 | $865.68 |
| # AnalystsCovering analysts | 12 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.3% |
REGN leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). VIR leads in 1 (Valuation Metrics). 2 tied.
VIR vs REGN: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is VIR or REGN a better buy right now?
For growth investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger pick with 1. 0% revenue growth year-over-year, versus -7. 6% for Vir Biotechnology, Inc. (VIR). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 4x trailing P/E (15. 6x forward), making it the more compelling value choice. Analysts rate Vir Biotechnology, Inc. (VIR) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — VIR or REGN?
Over the past 5 years, Regeneron Pharmaceuticals, Inc.
(REGN) delivered a total return of +45. 4%, compared to -75. 3% for Vir Biotechnology, Inc. (VIR). Over 10 years, the gap is even starker: REGN returned +96. 0% versus VIR's -26. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — VIR or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 81β versus Vir Biotechnology, Inc. 's 2. 05β — meaning VIR is approximately 155% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 24% for Vir Biotechnology, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — VIR or REGN?
By revenue growth (latest reported year), Regeneron Pharmaceuticals, Inc.
(REGN) is pulling ahead at 1. 0% versus -7. 6% for Vir Biotechnology, Inc. (VIR). On earnings-per-share growth, the picture is similar: Vir Biotechnology, Inc. grew EPS 17. 5% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — VIR or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -638. 9% for Vir Biotechnology, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus -682. 7% for VIR. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is VIR or REGN more undervalued right now?
Analyst consensus price targets imply the most upside for VIR: 106.
9% to $21. 29.
07Which pays a better dividend — VIR or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. VIR does not pay a meaningful dividend and should not be held primarily for income.
08Is VIR or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Vir Biotechnology, Inc. (VIR) carries a higher beta of 2. 05 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +96. 0%, VIR: -26. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between VIR and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: VIR is a small-cap quality compounder stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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