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VKTX vs GPCR vs TERN vs PEPG
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
VKTX vs GPCR vs TERN vs PEPG — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $3.66B | $2.25B | $4.63B | $123M |
| Revenue (TTM) | $0.00 | $0.00 | $0.00 | $0.00 |
| Net Income (TTM) | $-472M | $-170M | $-94M | $-90M |
| Total Debt | $137K | $6M | $1M | $17M |
| Cash & Equiv. | $166M | $800M | $161M | $61M |
VKTX vs GPCR vs TERN vs PEPG — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 23 | May 26 | Return |
|---|---|---|---|
| Viking Therapeutics… (VKTX) | 100 | 286.8 | +186.8% |
| Structure Therapeut… (GPCR) | 100 | 153.2 | +53.2% |
| Terns Pharmaceutica… (TERN) | 100 | 522.5 | +422.5% |
| PepGen Inc. (PEPG) | 100 | 11.7 | -88.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: VKTX vs GPCR vs TERN vs PEPG
Each card shows where this stock fits in a portfolio — not just who wins on paper.
VKTX is the #2 pick in this set and the best alternative if long-term compounding is your priority.
- 25.8% 10Y total return vs TERN's 187.9%
- 4.7% margin vs GPCR's 2.3%
GPCR is the clearest fit if your priority is efficiency.
- -14.4% ROA vs VKTX's -65.3%, ROIC -30.3% vs -44.4%
TERN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.39, Low D/E 0.4%, current ratio 23.14x
- +16.5% vs VKTX's +14.6%
PEPG carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.17
- EPS growth 25.6%
- Beta 0.17, current ratio 11.94x
- -1.0% revenue growth vs VKTX's -270.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -1.0% revenue growth vs VKTX's -270.1% | |
| Quality / Margins | 4.7% margin vs GPCR's 2.3% | |
| Stability / Safety | Beta 0.17 vs VKTX's 1.61 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +16.5% vs VKTX's +14.6% | |
| Efficiency (ROA) | -14.4% ROA vs VKTX's -65.3%, ROIC -30.3% vs -44.4% |
VKTX vs GPCR vs TERN vs PEPG — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PEPG leads in 1 of 6 categories
GPCR leads 1 • TERN leads 1 • VKTX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
PEPG leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
VKTX and PEPG operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $0 | $0 |
| EBITDAEarnings before interest/tax | -$502M | -$209M | -$108M | -$90M |
| Net IncomeAfter-tax profit | -$472M | -$170M | -$94M | -$90M |
| Free Cash FlowCash after capex | -$340M | -$159M | -$78M | -$82M |
| Gross MarginGross profit ÷ Revenue | — | — | — | — |
| Operating MarginEBIT ÷ Revenue | — | — | — | — |
| Net MarginNet income ÷ Revenue | — | — | — | — |
| FCF MarginFCF ÷ Revenue | — | — | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | -2.3% | -29.6% | +3.6% | +60.3% |
Valuation Metrics
Evenly matched — TERN and PEPG each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $3.7B | $2.3B | $4.6B | $123M |
| Enterprise ValueMkt cap + debt − cash | $3.5B | $1.5B | $4.5B | $80M |
| Trailing P/EPrice ÷ TTM EPS | -9.90x | -16.31x | -47.28x | -0.84x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | — | — |
| Price / BookPrice ÷ Book value/share | 5.57x | 1.53x | 12.17x | 0.51x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
GPCR leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
GPCR delivers a -15.1% return on equity — every $100 of shareholder capital generates $-15 in annual profit, vs $-76 for PEPG. VKTX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to PEPG's 0.12x. On the Piotroski fundamental quality scale (0–9), PEPG scores 4/9 vs VKTX's 2/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -71.3% | -15.1% | -30.0% | -75.7% |
| ROA (TTM)Return on assets | -65.3% | -14.4% | -28.5% | -60.4% |
| ROICReturn on invested capital | -44.4% | -30.3% | -42.2% | -73.2% |
| ROCEReturn on capital employed | -51.8% | -24.1% | -33.7% | -63.4% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 3 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.00x | 0.00x | 0.12x |
| Net DebtTotal debt minus cash | -$166M | -$793M | -$160M | -$44M |
| Cash & Equiv.Liquid assets | $166M | $800M | $161M | $61M |
| Total DebtShort + long-term debt | $137,000 | $6M | $1M | $17M |
| Interest CoverageEBIT ÷ Interest expense | -15687.44x | — | — | — |
Total Returns (Dividends Reinvested)
TERN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in VKTX five years ago would be worth $53,526 today (with dividends reinvested), compared to $1,389 for PEPG. Over the past 12 months, TERN leads with a +1647.5% total return vs VKTX's +14.6%. The 3-year compound annual growth rate (CAGR) favors TERN at 59.1% vs PEPG's -50.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -10.8% | -42.5% | +32.0% | -75.0% |
| 1-Year ReturnPast 12 months | +14.6% | +47.2% | +1647.5% | +42.1% |
| 3-Year ReturnCumulative with dividends | +38.1% | +63.1% | +302.7% | -88.1% |
| 5-Year ReturnCumulative with dividends | +435.3% | +50.6% | +218.6% | -86.1% |
| 10-Year ReturnCumulative with dividends | +2576.3% | +50.6% | +187.9% | -86.1% |
| CAGR (3Y)Annualised 3-year return | +11.4% | +17.7% | +59.1% | -50.7% |
Risk & Volatility
Evenly matched — TERN and PEPG each lead in 1 of 2 comparable metrics.
Risk & Volatility
PEPG is the less volatile stock with a 0.17 beta — it tends to amplify market swings less than VKTX's 1.61 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TERN currently trades 99.6% from its 52-week high vs PEPG's 22.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.61x | 0.96x | 0.39x | 0.17x |
| 52-Week HighHighest price in past year | $43.15 | $94.90 | $53.18 | $7.80 |
| 52-Week LowLowest price in past year | $22.96 | $15.80 | $2.66 | $1.01 |
| % of 52W HighCurrent price vs 52-week peak | +73.2% | +41.3% | +99.6% | +22.9% |
| RSI (14)Momentum oscillator 0–100 | 47.1 | 30.2 | 74.2 | 37.6 |
| Avg Volume (50D)Average daily shares traded | 2.3M | 953K | 6.7M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: VKTX as "Buy", GPCR as "Buy", TERN as "Buy", PEPG as "Buy". Consensus price targets imply 291.1% upside for PEPG (target: $7) vs 4.9% for TERN (target: $56).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $100.75 | $114.75 | $55.56 | $7.00 |
| # AnalystsCovering analysts | 24 | 14 | 16 | 6 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
PEPG leads in 1 of 6 categories (Income & Cash Flow). GPCR leads in 1 (Profitability & Efficiency). 2 tied.
VKTX vs GPCR vs TERN vs PEPG: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is VKTX or GPCR or TERN or PEPG a better buy right now?
Analysts rate Viking Therapeutics, Inc.
(VKTX) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — VKTX or GPCR or TERN or PEPG?
Over the past 5 years, Viking Therapeutics, Inc.
(VKTX) delivered a total return of +435. 3%, compared to -86. 1% for PepGen Inc. (PEPG). Over 10 years, the gap is even starker: VKTX returned +25. 8% versus PEPG's -86. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — VKTX or GPCR or TERN or PEPG?
By beta (market sensitivity over 5 years), PepGen Inc.
(PEPG) is the lower-risk stock at 0. 17β versus Viking Therapeutics, Inc. 's 1. 61β — meaning VKTX is approximately 829% more volatile than PEPG relative to the S&P 500. On balance sheet safety, Viking Therapeutics, Inc. (VKTX) carries a lower debt/equity ratio of 0% versus 12% for PepGen Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — VKTX or GPCR or TERN or PEPG?
On earnings-per-share growth, the picture is similar: PepGen Inc.
grew EPS 25. 6% year-over-year, compared to -215. 8% for Viking Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — VKTX or GPCR or TERN or PEPG?
Viking Therapeutics, Inc.
(VKTX) is the more profitable company, earning 0. 0% net margin versus 0. 0% for PepGen Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: VKTX leads at 0. 0% versus 0. 0% for PEPG. At the gross margin level — before operating expenses — VKTX leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — VKTX or GPCR or TERN or PEPG?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is VKTX or GPCR or TERN or PEPG better for a retirement portfolio?
For long-horizon retirement investors, PepGen Inc.
(PEPG) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 17)). Viking Therapeutics, Inc. (VKTX) carries a higher beta of 1. 61 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PEPG: -86. 1%, VKTX: +25. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between VKTX and GPCR and TERN and PEPG?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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