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Stock Comparison

XTLB vs BFRI

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
XTLB
XTL Biopharmaceuticals Ltd.

Biotechnology

HealthcareNASDAQ • IL
Market Cap$294K
5Y Perf.-82.5%
BFRI
Biofrontera Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$13M
5Y Perf.-98.7%

XTLB vs BFRI — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
XTLB logoXTLB
BFRI logoBFRI
IndustryBiotechnologyDrug Manufacturers - Specialty & Generic
Market Cap$294K$13M
Revenue (TTM)$451K$42M
Net Income (TTM)$-1M$-11M
Gross Margin26.4%75.8%
Operating Margin-481.6%-27.2%
Total Debt$138K$6M
Cash & Equiv.$371K$6M

XTLB vs BFRILong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

XTLB
BFRI
StockOct 21May 26Return
XTL Biopharmaceutic… (XTLB)10017.5-82.5%
Biofrontera Inc. (BFRI)1001.3-98.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: XTLB vs BFRI

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BFRI leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. XTL Biopharmaceuticals Ltd. is the stronger pick specifically for operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
XTLB
XTL Biopharmaceuticals Ltd.
The Long-Run Compounder

XTLB is the clearest fit if your priority is long-term compounding.

  • -87.3% 10Y total return vs BFRI's -98.7%
  • -17.7% ROA vs BFRI's -52.2%, ROIC -54.1% vs -124.3%
Best for: long-term compounding
BFRI
Biofrontera Inc.
The Income Pick

BFRI carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.67
  • Rev growth 11.8%, EPS growth 100.0%, 3Y rev CAGR 13.3%
  • Lower volatility, beta 1.67, Low D/E 58.8%, current ratio 1.52x
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBFRI logoBFRI11.8% revenue growth vs XTLB's -173.2%
Quality / MarginsBFRI logoBFRI-25.3% margin vs XTLB's -227.7%
Stability / SafetyBFRI logoBFRIBeta 1.67 vs XTLB's 1.71
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)BFRI logoBFRI+62.5% vs XTLB's -50.9%
Efficiency (ROA)XTLB logoXTLB-17.7% ROA vs BFRI's -52.2%, ROIC -54.1% vs -124.3%

XTLB vs BFRI — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

XTLBXTL Biopharmaceuticals Ltd.

Segment breakdown not available.

BFRIBiofrontera Inc.
FY 2023
Government and Payor Rebates
58.2%$310,000
Co-pay Assistance Program
31.0%$165,000
Returns
9.8%$52,000
Prompt Pay Discounts
1.1%$6,000

XTLB vs BFRI — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBFRILAGGINGXTLB

Income & Cash Flow (Last 12 Months)

BFRI leads this category, winning 5 of 5 comparable metrics.

BFRI is the larger business by revenue, generating $42M annually — 92.5x XTLB's $451,000. Profitability is closely matched — net margins range from -25.3% (BFRI) to -2.3% (XTLB).

MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
RevenueTrailing 12 months$451,000$42M
EBITDAEarnings before interest/tax-$1M-$11M
Net IncomeAfter-tax profit-$1M-$11M
Free Cash FlowCash after capex$0-$13M
Gross MarginGross profit ÷ Revenue+26.4%+75.8%
Operating MarginEBIT ÷ Revenue-4.8%-27.2%
Net MarginNet income ÷ Revenue-2.3%-25.3%
FCF MarginFCF ÷ Revenue-3.7%-32.0%
Rev. Growth (YoY)Latest quarter vs prior year+36.2%
EPS Growth (YoY)Latest quarter vs prior year+20.0%+100.0%
BFRI leads this category, winning 5 of 5 comparable metrics.

Valuation Metrics

BFRI leads this category, winning 1 of 1 comparable metric.
MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
Market CapShares × price$293,767$13M
Enterprise ValueMkt cap + debt − cash$60,767$13M
Trailing P/EPrice ÷ TTM EPS-0.28x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue0.65x0.32x
Price / BookPrice ÷ Book value/share0.05x
Price / FCFMarket cap ÷ FCF
BFRI leads this category, winning 1 of 1 comparable metric.

Profitability & Efficiency

XTLB leads this category, winning 8 of 9 comparable metrics.

XTLB delivers a -25.5% return on equity — every $100 of shareholder capital generates $-26 in annual profit, vs $-11 for BFRI. XTLB carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to BFRI's 0.59x. On the Piotroski fundamental quality scale (0–9), BFRI scores 4/9 vs XTLB's 3/9, reflecting mixed financial health.

MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
ROE (TTM)Return on equity-25.5%-11.4%
ROA (TTM)Return on assets-17.7%-52.2%
ROICReturn on invested capital-54.1%-124.3%
ROCEReturn on capital employed-50.7%-84.8%
Piotroski ScoreFundamental quality 0–934
Debt / EquityFinancial leverage0.03x0.59x
Net DebtTotal debt minus cash-$233,000-$231,000
Cash & Equiv.Liquid assets$371,000$6M
Total DebtShort + long-term debt$138,000$6M
Interest CoverageEBIT ÷ Interest expense-13.31x-69.93x
XTLB leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

XTLB leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in XTLB five years ago would be worth $1,963 today (with dividends reinvested), compared to $129 for BFRI. Over the past 12 months, BFRI leads with a +62.5% total return vs XTLB's -50.9%. The 3-year compound annual growth rate (CAGR) favors XTLB at -18.4% vs BFRI's -54.4% — a key indicator of consistent wealth creation.

MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
YTD ReturnYear-to-date+11.3%+57.2%
1-Year ReturnPast 12 months-50.9%+62.5%
3-Year ReturnCumulative with dividends-45.7%-90.5%
5-Year ReturnCumulative with dividends-80.4%-98.7%
10-Year ReturnCumulative with dividends-87.3%-98.7%
CAGR (3Y)Annualised 3-year return-18.4%-54.4%
XTLB leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

BFRI leads this category, winning 2 of 2 comparable metrics.

BFRI is the less volatile stock with a 1.67 beta — it tends to amplify market swings less than XTLB's 1.71 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BFRI currently trades 95.8% from its 52-week high vs XTLB's 26.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
Beta (5Y)Sensitivity to S&P 5001.71x1.67x
52-Week HighHighest price in past year$10.28$1.19
52-Week LowLowest price in past year$1.05$0.54
% of 52W HighCurrent price vs 52-week peak+26.0%+95.8%
RSI (14)Momentum oscillator 0–10057.063.6
Avg Volume (50D)Average daily shares traded2.4M122K
BFRI leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricXTLB logoXTLBXTL Biopharmaceut…BFRI logoBFRIBiofrontera Inc.
Analyst RatingConsensus buy/hold/sell
Price TargetConsensus 12-month target
# AnalystsCovering analysts
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

BFRI leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). XTLB leads in 2 (Profitability & Efficiency, Total Returns).

Best OverallBiofrontera Inc. (BFRI)Leads 3 of 6 categories
Loading custom metrics...

XTLB vs BFRI: Frequently Asked Questions

6 questions · data-driven answers · updated daily

01

Which is the better long-term investment — XTLB or BFRI?

Over the past 5 years, XTL Biopharmaceuticals Ltd.

(XTLB) delivered a total return of -80. 4%, compared to -98. 7% for Biofrontera Inc. (BFRI). Over 10 years, the gap is even starker: XTLB returned -87. 3% versus BFRI's -98. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

02

Which is safer — XTLB or BFRI?

By beta (market sensitivity over 5 years), Biofrontera Inc.

(BFRI) is the lower-risk stock at 1. 67β versus XTL Biopharmaceuticals Ltd. 's 1. 71β — meaning XTLB is approximately 2% more volatile than BFRI relative to the S&P 500. On balance sheet safety, XTL Biopharmaceuticals Ltd. (XTLB) carries a lower debt/equity ratio of 3% versus 59% for Biofrontera Inc. — giving it more financial flexibility in a downturn.

03

Which has better profit margins — XTLB or BFRI?

Biofrontera Inc.

(BFRI) is the more profitable company, earning -25. 3% net margin versus -227. 7% for XTL Biopharmaceuticals Ltd. — meaning it keeps -25. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BFRI leads at -27. 2% versus -481. 6% for XTLB. At the gross margin level — before operating expenses — BFRI leads at 75. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

04

Which pays a better dividend — XTLB or BFRI?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

05

Is XTLB or BFRI better for a retirement portfolio?

For long-horizon retirement investors, Biofrontera Inc.

(BFRI) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. XTL Biopharmaceuticals Ltd. (XTLB) carries a higher beta of 1. 71 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BFRI: -98. 7%, XTLB: -87. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

06

What are the main differences between XTLB and BFRI?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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XTLB

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  • Market Cap > $20B
  • Gross Margin > 15%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 18%
  • Gross Margin > 45%
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