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Stock Comparison

XTLB vs NRXP vs SIGA vs BFRI vs AEYE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
XTLB
XTL Biopharmaceuticals Ltd.

Biotechnology

HealthcareNASDAQ • IL
Market Cap$294K
5Y Perf.-82.5%
NRXP
NRx Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$85M
5Y Perf.-97.0%
SIGA
SIGA Technologies, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$339M
5Y Perf.-34.4%
BFRI
Biofrontera Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$13M
5Y Perf.-98.7%
AEYE
AudioEye, Inc.

Software - Application

TechnologyNASDAQ • US
Market Cap$100M
5Y Perf.-18.6%

XTLB vs NRXP vs SIGA vs BFRI vs AEYE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
XTLB logoXTLB
NRXP logoNRXP
SIGA logoSIGA
BFRI logoBFRI
AEYE logoAEYE
IndustryBiotechnologyBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericSoftware - Application
Market Cap$294K$85M$339M$13M$100M
Revenue (TTM)$451K$242K$94M$42M$40M
Net Income (TTM)$-1M$-38M$-4.04T$-11M$-3M
Gross Margin26.4%59.5%61.8%75.8%78.3%
Operating Margin-481.6%-63.0%27.7%-27.2%-7.9%
Forward P/E2.8x
Total Debt$138K$631K$595K$6M$721K
Cash & Equiv.$371K$8M$155M$6M$5M

XTLB vs NRXP vs SIGA vs BFRI vs AEYELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

XTLB
NRXP
SIGA
BFRI
AEYE
StockOct 21May 26Return
XTL Biopharmaceutic… (XTLB)10017.5-82.5%
NRx Pharmaceuticals… (NRXP)1003.0-97.0%
SIGA Technologies, … (SIGA)10065.6-34.4%
Biofrontera Inc. (BFRI)1001.3-98.7%
AudioEye, Inc. (AEYE)10081.4-18.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: XTLB vs NRXP vs SIGA vs BFRI vs AEYE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SIGA leads in 3 of 6 categories (5-stock set), making it the strongest pick for capital preservation and lower volatility and dividend income and shareholder returns. NRx Pharmaceuticals, Inc. is the stronger pick specifically for growth and revenue expansion. BFRI and AEYE also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
XTLB
XTL Biopharmaceuticals Ltd.
The Healthcare Pick

Among these 5 stocks, XTLB doesn't own a clear edge in any measured category.

Best for: healthcare exposure
NRXP
NRx Pharmaceuticals, Inc.
The Growth Leader

NRXP is the #2 pick in this set and the best alternative if growth is your priority.

  • 101.1% revenue growth vs XTLB's -173.2%
Best for: growth
SIGA
SIGA Technologies, Inc.
The Income Pick

SIGA carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 4 yrs, beta 1.15, yield 12.7%
  • 7.6% 10Y total return vs AEYE's 102.2%
  • Lower volatility, beta 1.15, Low D/E 0.3%, current ratio 11.83x
  • Beta 1.15, yield 12.7%, current ratio 11.83x
Best for: income & stability and long-term compounding
BFRI
Biofrontera Inc.
The Growth Play

BFRI ranks third and is worth considering specifically for growth exposure.

  • Rev growth 11.8%, EPS growth 100.0%, 3Y rev CAGR 13.3%
  • +62.5% vs XTLB's -50.9%
Best for: growth exposure
AEYE
AudioEye, Inc.
The Quality Compounder

AEYE is the clearest fit if your priority is quality.

  • -7.6% margin vs SIGA's -43K%
Best for: quality
See the full category breakdown
CategoryWinnerWhy
GrowthNRXP logoNRXP101.1% revenue growth vs XTLB's -173.2%
Quality / MarginsAEYE logoAEYE-7.6% margin vs SIGA's -43K%
Stability / SafetySIGA logoSIGABeta 1.15 vs AEYE's 2.29, lower leverage
DividendsSIGA logoSIGA12.7% yield; 4-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)BFRI logoBFRI+62.5% vs XTLB's -50.9%
Efficiency (ROA)SIGA logoSIGA-7.4% ROA vs NRXP's -489.9%

XTLB vs NRXP vs SIGA vs BFRI vs AEYE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

XTLBXTL Biopharmaceuticals Ltd.

Segment breakdown not available.

NRXPNRx Pharmaceuticals, Inc.
FY 2025
Therapy
100.0%$854,000
SIGASIGA Technologies, Inc.
FY 2025
Product Sales and Supportive Services
93.1%$88M
Research and Development
6.9%$7M
BFRIBiofrontera Inc.
FY 2023
Government and Payor Rebates
58.2%$310,000
Co-pay Assistance Program
31.0%$165,000
Returns
9.8%$52,000
Prompt Pay Discounts
1.1%$6,000
AEYEAudioEye, Inc.
FY 2024
Enterprise
100.0%$15M

XTLB vs NRXP vs SIGA vs BFRI vs AEYE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSIGALAGGINGAEYE

Income & Cash Flow (Last 12 Months)

Evenly matched — SIGA and BFRI and AEYE each lead in 2 of 6 comparable metrics.

SIGA is the larger business by revenue, generating $94M annually — 387.5x NRXP's $242,000. AEYE is the more profitable business, keeping -7.6% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, BFRI holds the edge at +36.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
RevenueTrailing 12 months$451,000$242,000$94M$42M$40M
EBITDAEarnings before interest/tax-$1M-$31M$26M-$11M-$504,000
Net IncomeAfter-tax profit-$1M-$38M-$4.04T-$11M-$3M
Free Cash FlowCash after capex$0-$12M$33M-$13M$2M
Gross MarginGross profit ÷ Revenue+26.4%+59.5%+61.8%+75.8%+78.3%
Operating MarginEBIT ÷ Revenue-4.8%-63.0%+27.7%-27.2%-7.9%
Net MarginNet income ÷ Revenue-2.3%-157.3%-43117.4%-25.3%-7.6%
FCF MarginFCF ÷ Revenue-3.7%-49.0%+35.2%-32.0%+5.5%
Rev. Growth (YoY)Latest quarter vs prior year-11.3%+36.2%+7.9%
EPS Growth (YoY)Latest quarter vs prior year+20.0%-80.0%+100.0%+29.0%
Evenly matched — SIGA and BFRI and AEYE each lead in 2 of 6 comparable metrics.

Valuation Metrics

Evenly matched — XTLB and BFRI and AEYE each lead in 1 of 3 comparable metrics.
MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
Market CapShares × price$293,767$85M$339M$13M$100M
Enterprise ValueMkt cap + debt − cash$60,767$78M$185M$13M$96M
Trailing P/EPrice ÷ TTM EPS-0.28x-2.28x14.33x-32.36x
Forward P/EPrice ÷ next-FY EPS est.2.78x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple7.60x
Price / SalesMarket cap ÷ Revenue0.65x69.15x3.58x0.32x2.49x
Price / BookPrice ÷ Book value/share0.05x1.70x20.91x
Price / FCFMarket cap ÷ FCF6.96x
Evenly matched — XTLB and BFRI and AEYE each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

SIGA leads this category, winning 7 of 9 comparable metrics.

SIGA delivers a -10.7% return on equity — every $100 of shareholder capital generates $-11 in annual profit, vs $-11 for BFRI. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to BFRI's 0.59x. On the Piotroski fundamental quality scale (0–9), NRXP scores 5/9 vs XTLB's 3/9, reflecting solid financial health.

MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
ROE (TTM)Return on equity-25.5%-10.7%-11.4%-47.8%
ROA (TTM)Return on assets-17.7%-4.9%-7.4%-52.2%-9.5%
ROICReturn on invested capital-54.1%+33.7%-124.3%-42.4%
ROCEReturn on capital employed-50.7%+11.3%-84.8%-17.7%
Piotroski ScoreFundamental quality 0–935544
Debt / EquityFinancial leverage0.03x0.00x0.59x0.15x
Net DebtTotal debt minus cash-$233,000-$7M-$154M-$231,000-$5M
Cash & Equiv.Liquid assets$371,000$8M$155M$6M$5M
Total DebtShort + long-term debt$138,000$631,000$595,169$6M$721,000
Interest CoverageEBIT ÷ Interest expense-13.31x-24.18x-69.93x-2.79x
SIGA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

SIGA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in SIGA five years ago would be worth $10,136 today (with dividends reinvested), compared to $92 for NRXP. Over the past 12 months, BFRI leads with a +62.5% total return vs XTLB's -50.9%. The 3-year compound annual growth rate (CAGR) favors SIGA at 6.9% vs BFRI's -54.4% — a key indicator of consistent wealth creation.

MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
YTD ReturnYear-to-date+11.3%+16.8%-15.0%+57.2%-18.7%
1-Year ReturnPast 12 months-50.9%+55.3%+1.5%+62.5%-27.9%
3-Year ReturnCumulative with dividends-45.7%-50.6%+22.2%-90.5%+20.6%
5-Year ReturnCumulative with dividends-80.4%-99.1%+1.4%-98.7%-60.2%
10-Year ReturnCumulative with dividends-87.3%-96.8%+764.0%-98.7%+102.2%
CAGR (3Y)Annualised 3-year return-18.4%-21.0%+6.9%-54.4%+6.4%
SIGA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SIGA and BFRI each lead in 1 of 2 comparable metrics.

SIGA is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than AEYE's 2.29 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BFRI currently trades 95.8% from its 52-week high vs XTLB's 26.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
Beta (5Y)Sensitivity to S&P 5001.71x1.91x1.15x1.67x2.29x
52-Week HighHighest price in past year$10.28$3.84$9.62$1.19$16.39
52-Week LowLowest price in past year$1.05$1.62$4.29$0.54$5.31
% of 52W HighCurrent price vs 52-week peak+26.0%+79.7%+49.2%+95.8%+49.4%
RSI (14)Momentum oscillator 0–10057.064.747.063.661.3
Avg Volume (50D)Average daily shares traded2.4M913K688K122K194K
Evenly matched — SIGA and BFRI each lead in 1 of 2 comparable metrics.

Analyst Outlook

SIGA leads this category, winning 1 of 1 comparable metric.

SIGA is the only dividend payer here at 12.73% yield — a key consideration for income-focused portfolios.

MetricXTLB logoXTLBXTL Biopharmaceut…NRXP logoNRXPNRx Pharmaceutica…SIGA logoSIGASIGA Technologies…BFRI logoBFRIBiofrontera Inc.AEYE logoAEYEAudioEye, Inc.
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target
# AnalystsCovering analysts1
Dividend YieldAnnual dividend ÷ price+12.7%
Dividend StreakConsecutive years of raises41
Dividend / ShareAnnual DPS$0.60
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
SIGA leads this category, winning 1 of 1 comparable metric.
Key Takeaway

SIGA leads in 3 of 6 categories — strongest in Profitability & Efficiency and Total Returns. 3 categories are tied.

Best OverallSIGA Technologies, Inc. (SIGA)Leads 3 of 6 categories
Loading custom metrics...

XTLB vs NRXP vs SIGA vs BFRI vs AEYE: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is XTLB or NRXP or SIGA or BFRI or AEYE a better buy right now?

For growth investors, AudioEye, Inc.

(AEYE) is the stronger pick with 14. 5% revenue growth year-over-year, versus -31. 8% for SIGA Technologies, Inc. (SIGA). SIGA Technologies, Inc. (SIGA) offers the better valuation at 14. 3x trailing P/E (2. 8x forward), making it the more compelling value choice. Analysts rate SIGA Technologies, Inc. (SIGA) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — XTLB or NRXP or SIGA or BFRI or AEYE?

Over the past 5 years, SIGA Technologies, Inc.

(SIGA) delivered a total return of +1. 4%, compared to -99. 1% for NRx Pharmaceuticals, Inc. (NRXP). Over 10 years, the gap is even starker: SIGA returned +764. 0% versus BFRI's -98. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — XTLB or NRXP or SIGA or BFRI or AEYE?

By beta (market sensitivity over 5 years), SIGA Technologies, Inc.

(SIGA) is the lower-risk stock at 1. 15β versus AudioEye, Inc. 's 2. 29β — meaning AEYE is approximately 99% more volatile than SIGA relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 59% for Biofrontera Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — XTLB or NRXP or SIGA or BFRI or AEYE?

By revenue growth (latest reported year), AudioEye, Inc.

(AEYE) is pulling ahead at 14. 5% versus -31. 8% for SIGA Technologies, Inc. (SIGA). On earnings-per-share growth, the picture is similar: Biofrontera Inc. grew EPS 100. 0% year-over-year, compared to -60. 2% for SIGA Technologies, Inc.. Over a 3-year CAGR, BFRI leads at 13. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — XTLB or NRXP or SIGA or BFRI or AEYE?

SIGA Technologies, Inc.

(SIGA) is the more profitable company, earning 24. 6% net margin versus -23. 4% for NRx Pharmaceuticals, Inc. — meaning it keeps 24. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: SIGA leads at 25. 1% versus -1324. 4% for NRXP. At the gross margin level — before operating expenses — AEYE leads at 78. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — XTLB or NRXP or SIGA or BFRI or AEYE?

In this comparison, SIGA (12.

7% yield) pays a dividend. XTLB, NRXP, BFRI, AEYE do not pay a meaningful dividend and should not be held primarily for income.

07

Is XTLB or NRXP or SIGA or BFRI or AEYE better for a retirement portfolio?

For long-horizon retirement investors, SIGA Technologies, Inc.

(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), 12. 7% yield, +764. 0% 10Y return). NRx Pharmaceuticals, Inc. (NRXP) carries a higher beta of 1. 91 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +764. 0%, NRXP: -96. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between XTLB and NRXP and SIGA and BFRI and AEYE?

These companies operate in different sectors (XTLB (Healthcare) and NRXP (Healthcare) and SIGA (Healthcare) and BFRI (Healthcare) and AEYE (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: XTLB is a small-cap quality compounder stock; NRXP is a small-cap quality compounder stock; SIGA is a small-cap deep-value stock; BFRI is a small-cap quality compounder stock; AEYE is a small-cap quality compounder stock. SIGA pays a dividend while XTLB, NRXP, BFRI, AEYE do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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XTLB

Quality Business

  • Sector: Healthcare
  • Market Cap > $20B
  • Gross Margin > 15%
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NRXP

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 35%
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SIGA

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 37%
  • Dividend Yield > 5.0%
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BFRI

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 18%
  • Gross Margin > 45%
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AEYE

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  • Sector: Technology
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Gross Margin > 46%
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