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Stock Comparison

ZLAB vs LEGN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ZLAB
Zai Lab Limited

Biotechnology

HealthcareNASDAQ • CN
Market Cap$2.06B
5Y Perf.-77.4%
LEGN
Legend Biotech Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.19B
5Y Perf.-33.9%

ZLAB vs LEGN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ZLAB logoZLAB
LEGN logoLEGN
IndustryBiotechnologyBiotechnology
Market Cap$2.06B$5.19B
Revenue (TTM)$453M$1.03B
Net Income (TTM)$-178M$-297M
Gross Margin57.9%60.3%
Operating Margin-53.5%-13.2%
Forward P/E116.2x
Total Debt$224M$414M
Cash & Equiv.$680M$902M

ZLAB vs LEGNLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ZLAB
LEGN
StockJun 20May 26Return
Zai Lab Limited (ZLAB)10022.6-77.4%
Legend Biotech Corp… (LEGN)10066.1-33.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: ZLAB vs LEGN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LEGN leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Zai Lab Limited is the stronger pick specifically for operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
ZLAB
Zai Lab Limited
The Defensive Pick

ZLAB is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 1.17, Low D/E 31.3%, current ratio 2.45x
  • -15.5% ROA vs LEGN's -17.6%, ROIC -41.7% vs -12.7%
Best for: sleep-well-at-night
LEGN
Legend Biotech Corporation
The Income Pick

LEGN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.76
  • Rev growth 64.5%, EPS growth -66.0%, 3Y rev CAGR 106.6%
  • -24.0% 10Y total return vs ZLAB's -33.4%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthLEGN logoLEGN64.5% revenue growth vs ZLAB's 15.3%
Quality / MarginsLEGN logoLEGN-28.8% margin vs ZLAB's -39.3%
Stability / SafetyLEGN logoLEGNBeta 0.76 vs ZLAB's 1.17
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)LEGN logoLEGN-12.2% vs ZLAB's -36.2%
Efficiency (ROA)ZLAB logoZLAB-15.5% ROA vs LEGN's -17.6%, ROIC -41.7% vs -12.7%

ZLAB vs LEGN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ZLABZai Lab Limited
FY 2025
Zejula
56.5%$189M
Nuzyra
18.2%$61M
Optune
14.4%$48M
Qinlock
10.6%$36M
Product and Service, Other
0.2%$717,000
LEGNLegend Biotech Corporation
FY 2021
Licensing Of Intellectual Property
100.0%$5M

ZLAB vs LEGN — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLEGNLAGGINGZLAB

Income & Cash Flow (Last 12 Months)

LEGN leads this category, winning 5 of 6 comparable metrics.

LEGN is the larger business by revenue, generating $1.0B annually — 2.3x ZLAB's $453M. LEGN is the more profitable business, keeping -28.8% of every revenue dollar as net income compared to ZLAB's -39.3%. On growth, LEGN holds the edge at +64.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
RevenueTrailing 12 months$453M$1.0B
EBITDAEarnings before interest/tax-$231M-$107M
Net IncomeAfter-tax profit-$178M-$297M
Free Cash FlowCash after capex-$108M-$231M
Gross MarginGross profit ÷ Revenue+57.9%+60.3%
Operating MarginEBIT ÷ Revenue-53.5%-13.2%
Net MarginNet income ÷ Revenue-39.3%-28.8%
FCF MarginFCF ÷ Revenue-23.9%-22.4%
Rev. Growth (YoY)Latest quarter vs prior year-6.5%+64.9%
EPS Growth (YoY)Latest quarter vs prior year-11.1%-2.2%
LEGN leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

ZLAB leads this category, winning 2 of 3 comparable metrics.
MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
Market CapShares × price$2.1B$5.2B
Enterprise ValueMkt cap + debt − cash$1.6B$4.7B
Trailing P/EPrice ÷ TTM EPS-11.63x-8.73x
Forward P/EPrice ÷ next-FY EPS est.116.25x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue4.47x5.03x
Price / BookPrice ÷ Book value/share2.85x2.59x
Price / FCFMarket cap ÷ FCF
ZLAB leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ZLAB leads this category, winning 5 of 9 comparable metrics.

ZLAB delivers a -24.3% return on equity — every $100 of shareholder capital generates $-24 in annual profit, vs $-29 for LEGN. ZLAB carries lower financial leverage with a 0.31x debt-to-equity ratio, signaling a more conservative balance sheet compared to LEGN's 0.41x. On the Piotroski fundamental quality scale (0–9), ZLAB scores 3/9 vs LEGN's 2/9, reflecting mixed financial health.

MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
ROE (TTM)Return on equity-24.3%-29.2%
ROA (TTM)Return on assets-15.5%-17.6%
ROICReturn on invested capital-41.7%-12.7%
ROCEReturn on capital employed-27.2%-11.0%
Piotroski ScoreFundamental quality 0–932
Debt / EquityFinancial leverage0.31x0.41x
Net DebtTotal debt minus cash-$455M-$488M
Cash & Equiv.Liquid assets$680M$902M
Total DebtShort + long-term debt$224M$414M
Interest CoverageEBIT ÷ Interest expense-81.89x-12.69x
ZLAB leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

LEGN leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in LEGN five years ago would be worth $9,584 today (with dividends reinvested), compared to $1,245 for ZLAB. Over the past 12 months, LEGN leads with a -12.2% total return vs ZLAB's -36.2%. The 3-year compound annual growth rate (CAGR) favors ZLAB at -20.5% vs LEGN's -25.8% — a key indicator of consistent wealth creation.

MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
YTD ReturnYear-to-date+7.3%+30.7%
1-Year ReturnPast 12 months-36.2%-12.2%
3-Year ReturnCumulative with dividends-49.7%-59.1%
5-Year ReturnCumulative with dividends-87.6%-4.2%
10-Year ReturnCumulative with dividends-33.4%-24.0%
CAGR (3Y)Annualised 3-year return-20.5%-25.8%
LEGN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

LEGN leads this category, winning 2 of 2 comparable metrics.

LEGN is the less volatile stock with a 0.76 beta — it tends to amplify market swings less than ZLAB's 1.17 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LEGN currently trades 62.1% from its 52-week high vs ZLAB's 41.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
Beta (5Y)Sensitivity to S&P 5001.17x0.76x
52-Week HighHighest price in past year$44.34$45.30
52-Week LowLowest price in past year$15.96$16.24
% of 52W HighCurrent price vs 52-week peak+41.9%+62.1%
RSI (14)Momentum oscillator 0–10041.074.8
Avg Volume (50D)Average daily shares traded743K1.9M
LEGN leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates ZLAB as "Buy" and LEGN as "Buy". Consensus price targets imply 105.9% upside for LEGN (target: $58) vs 88.2% for ZLAB (target: $35).

MetricZLAB logoZLABZai Lab LimitedLEGN logoLEGNLegend Biotech Co…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$35.00$57.89
# AnalystsCovering analysts1119
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

LEGN leads in 3 of 6 categories (Income & Cash Flow, Total Returns). ZLAB leads in 2 (Valuation Metrics, Profitability & Efficiency).

Best OverallLegend Biotech Corporation (LEGN)Leads 3 of 6 categories
Loading custom metrics...

ZLAB vs LEGN: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is ZLAB or LEGN a better buy right now?

For growth investors, Legend Biotech Corporation (LEGN) is the stronger pick with 64.

5% revenue growth year-over-year, versus 15. 3% for Zai Lab Limited (ZLAB). Analysts rate Zai Lab Limited (ZLAB) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ZLAB or LEGN?

Over the past 5 years, Legend Biotech Corporation (LEGN) delivered a total return of -4.

2%, compared to -87. 6% for Zai Lab Limited (ZLAB). Over 10 years, the gap is even starker: LEGN returned -24. 0% versus ZLAB's -33. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ZLAB or LEGN?

By beta (market sensitivity over 5 years), Legend Biotech Corporation (LEGN) is the lower-risk stock at 0.

76β versus Zai Lab Limited's 1. 17β — meaning ZLAB is approximately 55% more volatile than LEGN relative to the S&P 500. On balance sheet safety, Zai Lab Limited (ZLAB) carries a lower debt/equity ratio of 31% versus 41% for Legend Biotech Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — ZLAB or LEGN?

By revenue growth (latest reported year), Legend Biotech Corporation (LEGN) is pulling ahead at 64.

5% versus 15. 3% for Zai Lab Limited (ZLAB). On earnings-per-share growth, the picture is similar: Zai Lab Limited grew EPS 38. 5% year-over-year, compared to -66. 0% for Legend Biotech Corporation. Over a 3-year CAGR, LEGN leads at 106. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ZLAB or LEGN?

Legend Biotech Corporation (LEGN) is the more profitable company, earning -28.

8% net margin versus -38. 1% for Zai Lab Limited — meaning it keeps -28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LEGN leads at -13. 3% versus -48. 6% for ZLAB. At the gross margin level — before operating expenses — LEGN leads at 60. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is ZLAB or LEGN more undervalued right now?

Analyst consensus price targets imply the most upside for LEGN: 105.

9% to $57. 89.

07

Which pays a better dividend — ZLAB or LEGN?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is ZLAB or LEGN better for a retirement portfolio?

For long-horizon retirement investors, Legend Biotech Corporation (LEGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

76)). Both have compounded well over 10 years (LEGN: -24. 0%, ZLAB: -33. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ZLAB and LEGN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ZLAB

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 34%
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LEGN

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 32%
  • Gross Margin > 36%
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