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ZYXI vs UNH vs MCK vs INVA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ZYXI
Zynex, Inc.

Medical - Distribution

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-99.7%
UNH
UnitedHealth Group Incorporated

Medical - Healthcare Plans

HealthcareNYSE • US
Market Cap$335.60B
5Y Perf.-5.9%
MCK
McKesson Corporation

Medical - Distribution

HealthcareNYSE • US
Market Cap$92.15B
5Y Perf.+423.9%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+43.2%

ZYXI vs UNH vs MCK vs INVA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ZYXI logoZYXI
UNH logoUNH
MCK logoMCK
INVA logoINVA
IndustryMedical - DistributionMedical - Healthcare PlansMedical - DistributionBiotechnology
Market Cap$2M$335.60B$92.15B$1.93B
Revenue (TTM)$108M$449.71B$403.43B$424M
Net Income (TTM)$-74M$12.04B$4.76B$504M
Gross Margin71.6%18.8%3.6%76.2%
Operating Margin-62.8%4.2%1.5%14.8%
Forward P/E0.6x20.2x19.3x11.9x
Total Debt$74M$78.39B$7.39B$269M
Cash & Equiv.$40M$24.36B$5.69B$551M

ZYXI vs UNH vs MCK vs INVALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ZYXI
UNH
MCK
INVA
StockMay 20Mar 26Return
Zynex, Inc. (ZYXI)1000.3-99.7%
UnitedHealth Group … (UNH)10094.1-5.9%
McKesson Corporation (MCK)100523.9+423.9%
Innoviva, Inc. (INVA)100143.2+43.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ZYXI vs UNH vs MCK vs INVA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Zynex, Inc. is the stronger pick specifically for valuation and capital efficiency. UNH and MCK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
ZYXI
Zynex, Inc.
The Value Play

ZYXI is the #2 pick in this set and the best alternative if value is your priority.

  • Lower P/E (0.6x vs 11.9x)
Best for: value
UNH
UnitedHealth Group Incorporated
The Insurance Pick

UNH is the clearest fit if your priority is income & stability.

  • Dividend streak 25 yrs, beta 0.59, yield 2.4%
  • 2.4% yield, 25-year raise streak, vs ZYXI's 0.5%, (1 stock pays no dividend)
Best for: income & stability
MCK
McKesson Corporation
The Long-Run Compounder

MCK is the clearest fit if your priority is long-term compounding and valuation efficiency.

  • 348.1% 10Y total return vs UNH's 220.6%
  • PEG 0.49 vs INVA's 1.15
  • Beta 0.04, yield 0.4%, current ratio 0.90x
  • Beta 0.04 vs ZYXI's 4.55
Best for: long-term compounding and valuation efficiency
INVA
Innoviva, Inc.
The Growth Play

INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.

  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
  • 18.5% revenue growth vs ZYXI's 4.4%
  • 118.9% margin vs ZYXI's -68.4%
Best for: growth exposure and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthINVA logoINVA18.5% revenue growth vs ZYXI's 4.4%
ValueZYXI logoZYXILower P/E (0.6x vs 11.9x)
Quality / MarginsINVA logoINVA118.9% margin vs ZYXI's -68.4%
Stability / SafetyMCK logoMCKBeta 0.04 vs ZYXI's 4.55
DividendsUNH logoUNH2.4% yield, 25-year raise streak, vs ZYXI's 0.5%, (1 stock pays no dividend)
Momentum (1Y)INVA logoINVA+21.7% vs ZYXI's -97.4%
Efficiency (ROA)INVA logoINVA32.4% ROA vs ZYXI's -82.4%, ROIC 14.2% vs 6.1%

ZYXI vs UNH vs MCK vs INVA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ZYXIZynex, Inc.
FY 2024
Supplies
69.0%$133M
Device
31.0%$60M
UNHUnitedHealth Group Incorporated
FY 2025
Unitedhealthcare
94.4%$332.4B
Optumhealth
5.6%$19.8B
MCKMcKesson Corporation
FY 2025
U.S. Pharmaceutical Segment
91.3%$327.7B
International Segment
4.1%$14.7B
Medical-Surgical Solutions Segment
3.2%$11.4B
Prescription Technology Solutions
1.5%$5.2B
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M

ZYXI vs UNH vs MCK vs INVA — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLZYXILAGGINGINVA

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 6 of 6 comparable metrics.

UNH is the larger business by revenue, generating $449.7B annually — 4156.2x ZYXI's $108M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to ZYXI's -68.4%. On growth, INVA holds the edge at +10.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
RevenueTrailing 12 months$108M$449.7B$403.4B$424M
EBITDAEarnings before interest/tax-$64M$23.2B$6.8B$86M
Net IncomeAfter-tax profit-$74M$12.0B$4.8B$504M
Free Cash FlowCash after capex-$21M$19.7B$6.0B$181M
Gross MarginGross profit ÷ Revenue+71.6%+18.8%+3.6%+76.2%
Operating MarginEBIT ÷ Revenue-62.8%+4.2%+1.5%+14.8%
Net MarginNet income ÷ Revenue-68.4%+2.7%+1.2%+118.9%
FCF MarginFCF ÷ Revenue-19.4%+4.4%+1.5%+42.8%
Rev. Growth (YoY)Latest quarter vs prior year-73.3%+2.0%+6.0%+10.6%
EPS Growth (YoY)Latest quarter vs prior year-20.1%+0.7%+37.0%+4.0%
INVA leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

ZYXI leads this category, winning 5 of 7 comparable metrics.

At 0.6x trailing earnings, ZYXI trades at a 98% valuation discount to MCK's 29.2x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs MCK's 0.75x — a lower PEG means you pay less per unit of expected earnings growth.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
Market CapShares × price$2M$335.6B$92.1B$1.9B
Enterprise ValueMkt cap + debt − cash$36M$389.6B$93.8B$1.7B
Trailing P/EPrice ÷ TTM EPS0.61x27.95x29.25x6.91x
Forward P/EPrice ÷ next-FY EPS est.20.19x19.28x11.91x
PEG RatioP/E ÷ EPS growth rate0.75x0.67x
EV / EBITDAEnterprise value multiple3.33x16.70x18.74x8.10x
Price / SalesMarket cap ÷ Revenue0.01x0.75x0.26x4.55x
Price / BookPrice ÷ Book value/share0.05x3.31x1.65x
Price / FCFMarket cap ÷ FCF0.14x20.88x17.63x9.88x
ZYXI leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — MCK and INVA each lead in 4 of 9 comparable metrics.

MCK delivers a 3.0% return on equity — every $100 of shareholder capital generates $3 in annual profit, vs $-18 for ZYXI. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to ZYXI's 2.07x. On the Piotroski fundamental quality scale (0–9), ZYXI scores 6/9 vs INVA's 5/9, reflecting solid financial health.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
ROE (TTM)Return on equity-18.1%+11.5%+3.0%+46.5%
ROA (TTM)Return on assets-82.4%+3.9%+5.7%+32.4%
ROICReturn on invested capital+6.1%+9.2%+5.4%+14.2%
ROCEReturn on capital employed+5.4%+9.7%+30.5%+12.4%
Piotroski ScoreFundamental quality 0–96665
Debt / EquityFinancial leverage2.07x0.77x0.23x
Net DebtTotal debt minus cash$34M$54.0B$1.7B-$282M
Cash & Equiv.Liquid assets$40M$24.4B$5.7B$551M
Total DebtShort + long-term debt$74M$78.4B$7.4B$269M
Interest CoverageEBIT ÷ Interest expense-22.32x4.71x33.79x63.45x
Evenly matched — MCK and INVA each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

MCK leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in MCK five years ago would be worth $38,689 today (with dividends reinvested), compared to $111 for ZYXI. Over the past 12 months, INVA leads with a +21.7% total return vs ZYXI's -97.4%. The 3-year compound annual growth rate (CAGR) favors MCK at 27.3% vs ZYXI's -82.1% — a key indicator of consistent wealth creation.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
YTD ReturnYear-to-date-49.1%+10.6%-8.5%+14.7%
1-Year ReturnPast 12 months-97.4%-3.2%+4.6%+21.7%
3-Year ReturnCumulative with dividends-99.4%-19.9%+106.4%+95.2%
5-Year ReturnCumulative with dividends-98.9%-2.6%+286.9%+94.4%
10-Year ReturnCumulative with dividends-29.4%+220.6%+348.1%+94.9%
CAGR (3Y)Annualised 3-year return-82.1%-7.1%+27.3%+25.0%
MCK leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — UNH and MCK each lead in 1 of 2 comparable metrics.

MCK is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than ZYXI's 4.55 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. UNH currently trades 93.5% from its 52-week high vs ZYXI's 2.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
Beta (5Y)Sensitivity to S&P 5004.55x0.59x0.04x0.13x
52-Week HighHighest price in past year$2.82$395.52$999.00$25.15
52-Week LowLowest price in past year$0.02$234.60$637.00$16.52
% of 52W HighCurrent price vs 52-week peak+2.0%+93.5%+75.3%+90.7%
RSI (14)Momentum oscillator 0–10059.575.916.239.9
Avg Volume (50D)Average daily shares traded96K7.9M757K621K
Evenly matched — UNH and MCK each lead in 1 of 2 comparable metrics.

Analyst Outlook

UNH leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: UNH as "Buy", MCK as "Buy", INVA as "Buy". Consensus price targets imply 65.2% upside for INVA (target: $38) vs 4.2% for UNH (target: $385). For income investors, UNH offers the higher dividend yield at 2.35% vs MCK's 0.36%.

MetricZYXI logoZYXIZynex, Inc.UNH logoUNHUnitedHealth Grou…MCK logoMCKMcKesson Corporat…INVA logoINVAInnoviva, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$385.43$1006.50$37.67
# AnalystsCovering analysts523110
Dividend YieldAnnual dividend ÷ price+0.5%+2.4%+0.4%
Dividend StreakConsecutive years of raises125170
Dividend / ShareAnnual DPS$0.00$8.70$2.69
Buyback YieldShare repurchases ÷ mkt cap+100.0%+1.7%+3.4%+0.2%
UNH leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

INVA leads in 1 of 6 categories (Income & Cash Flow). ZYXI leads in 1 (Valuation Metrics). 2 tied.

Best OverallZynex, Inc. (ZYXI)Leads 1 of 6 categories
Loading custom metrics...

ZYXI vs UNH vs MCK vs INVA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ZYXI or UNH or MCK or INVA a better buy right now?

For growth investors, Innoviva, Inc.

(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus 4. 4% for Zynex, Inc. (ZYXI). Zynex, Inc. (ZYXI) offers the better valuation at 0. 6x trailing P/E, making it the more compelling value choice. Analysts rate UnitedHealth Group Incorporated (UNH) a "Buy" — based on 52 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ZYXI or UNH or MCK or INVA?

On trailing P/E, Zynex, Inc.

(ZYXI) is the cheapest at 0. 6x versus McKesson Corporation at 29. 2x. On forward P/E, Innoviva, Inc. is actually cheaper at 11. 9x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: McKesson Corporation wins at 0. 49x versus Innoviva, Inc. 's 1. 15x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ZYXI or UNH or MCK or INVA?

Over the past 5 years, McKesson Corporation (MCK) delivered a total return of +286.

9%, compared to -98. 9% for Zynex, Inc. (ZYXI). Over 10 years, the gap is even starker: MCK returned +348. 1% versus ZYXI's -29. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ZYXI or UNH or MCK or INVA?

By beta (market sensitivity over 5 years), McKesson Corporation (MCK) is the lower-risk stock at 0.

04β versus Zynex, Inc. 's 4. 55β — meaning ZYXI is approximately 10453% more volatile than MCK relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 2% for Zynex, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ZYXI or UNH or MCK or INVA?

By revenue growth (latest reported year), Innoviva, Inc.

(INVA) is pulling ahead at 18. 5% versus 4. 4% for Zynex, Inc. (ZYXI). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -66. 7% for Zynex, Inc.. Over a 3-year CAGR, ZYXI leads at 13. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ZYXI or UNH or MCK or INVA?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus 0. 9% for McKesson Corporation — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus 1. 2% for MCK. At the gross margin level — before operating expenses — ZYXI leads at 79. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ZYXI or UNH or MCK or INVA more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, McKesson Corporation (MCK) is the more undervalued stock at a PEG of 0. 49x versus Innoviva, Inc. 's 1. 15x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 11. 9x forward P/E versus 20. 2x for UnitedHealth Group Incorporated — 8. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INVA: 65. 2% to $37. 67.

08

Which pays a better dividend — ZYXI or UNH or MCK or INVA?

In this comparison, UNH (2.

4% yield), ZYXI (0. 5% yield), MCK (0. 4% yield) pay a dividend. INVA does not pay a meaningful dividend and should not be held primarily for income.

09

Is ZYXI or UNH or MCK or INVA better for a retirement portfolio?

For long-horizon retirement investors, McKesson Corporation (MCK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

04), +348. 1% 10Y return). Zynex, Inc. (ZYXI) carries a higher beta of 4. 55 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (MCK: +348. 1%, ZYXI: -29. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ZYXI and UNH and MCK and INVA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ZYXI is a small-cap deep-value stock; UNH is a large-cap quality compounder stock; MCK is a mid-cap high-growth stock; INVA is a small-cap high-growth stock. ZYXI, UNH pay a dividend while MCK, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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Beat Both

Find stocks that outperform ZYXI and UNH and MCK and INVA on the metrics below

Revenue Growth>
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(ZYXI: -73.3% · UNH: 2.0%)
P/E Ratio<
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(ZYXI: 0.6x · UNH: 27.9x)

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