Biotechnology
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Side-by-side financial analysisStock Comparison
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Biotechnology
Drug Manufacturers - General
Banks - Diversified
Beverages - Non-Alcoholic
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||||
|---|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Biotechnology | Drug Manufacturers - General | Banks - Diversified | Beverages - Non-Alcoholic |
| Market Cap | $3.19B | $397.56B | $82M | $298.30B | $875.80B | $355.22B |
| Revenue (TTM) | $1M | $61.16B | $0.00 | $64.93B | $280.33B | $49.28B |
| Net Income (TTM) | $-11M | $4.23B | $-89M | $18.25B | $57.05B | $13.70B |
| Gross Margin | 94.3% | 70.2% | — | 74.2% | 60.0% | 61.7% |
| Operating Margin | -143.2% | 26.7% | — | 41.1% | 25.9% | 29.3% |
| Forward P/E | — | 15.8x | — | 23.5x | 14.1x | 25.2x |
| Total Debt | $1M | $69.07B | $5M | $50.53B | $942.38B | $45.49B |
| Cash & Equiv. | $51M | $5.23B | $16M | $14.56B | $343.34B | $10.27B |
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 20 | Jun 26 | Return |
|---|---|---|---|
| Dianthus Therapeuti… (DNTH) | 100 | 68.1 | -31.9% |
| AbbVie Inc. (ABBV) | 100 | 236.8 | +136.8% |
| ALX Oncology Holdin… (ALXO) | 100 | 4.6 | -95.4% |
| Merck & Co., Inc. (MRK) | 100 | 157.9 | +57.9% |
| JPMorgan Chase & Co. (JPM) | 100 | 324.4 | +224.4% |
| The Coca-Cola Compa… (KO) | 100 | 174.7 | +74.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
DNTH ranks third and is worth considering specifically for momentum.
- +321.9% vs KO's +17.4%
ABBV has the current edge in this matchup, primarily because of its strength in income & stability and defensive.
- Dividend streak 43 yrs, beta 0.15, yield 2.9%
- Beta 0.15, yield 2.9%, current ratio 0.67x
- Beta 0.15 vs ALXO's 1.49
- 2.9% yield, 43-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
ALXO is the clearest fit if your priority is growth.
- 31.7% revenue growth vs DNTH's -67.3%
MRK is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 0.34, Low D/E 96.0%, current ratio 1.54x
- 28.1% margin vs DNTH's -8.5%
- 14.6% ROA vs ALXO's -85.6%, ROIC 22.0% vs -122.0%
JPM is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 454.4% 10Y total return vs ABBV's 357.3%
- PEG 1.08 vs KO's 2.26
- Lower P/E (14.1x vs 25.2x), PEG 1.08 vs 2.26
KO is the clearest fit if your priority is growth exposure.
- Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 31.7% revenue growth vs DNTH's -67.3% | |
| Value | Lower P/E (14.1x vs 25.2x), PEG 1.08 vs 2.26 | |
| Quality / Margins | 28.1% margin vs DNTH's -8.5% | |
| Stability / Safety | Beta 0.15 vs ALXO's 1.49 | |
| Dividends | 2.9% yield, 43-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +321.9% vs KO's +17.4% | |
| Efficiency (ROA) | 14.6% ROA vs ALXO's -85.6%, ROIC 22.0% vs -122.0% |
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO — Financial Metrics
Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
MRK leads in 1 of 6 categories
JPM leads 1 • DNTH leads 1 • KO leads 1 • ABBV leads 0 • ALXO leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
MRK leads this category, winning 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM and ALXO operate at a comparable scale, with $280.3B and $0 in trailing revenue. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to DNTH's -8.5%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||||
|---|---|---|---|---|---|---|
| RevenueTrailing 12 months | $1M | $61.2B | $0 | $64.9B | $280.3B | $49.3B |
| EBITDAEarnings before interest/tax | -$191M | $24.5B | -$91M | $32.4B | $81.4B | $15.5B |
| Net IncomeAfter-tax profit | -$11M | $4.2B | -$89M | $18.3B | $57.0B | $13.7B |
| Free Cash FlowCash after capex | -$130M | $18.7B | -$78M | $12.4B | $100.9B | $12.6B |
| Gross MarginGross profit ÷ Revenue | +94.3% | +70.2% | — | +74.2% | +60.0% | +61.7% |
| Operating MarginEBIT ÷ Revenue | -143.2% | +26.7% | — | +41.1% | +25.9% | +29.3% |
| Net MarginNet income ÷ Revenue | -8.5% | +6.9% | — | +28.1% | +20.4% | +27.8% |
| FCF MarginFCF ÷ Revenue | -97.7% | +30.6% | — | +19.0% | +36.0% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | -60.2% | +10.0% | — | +4.5% | — | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -3.7% | +57.4% | +43.1% | -19.6% | +16.0% | +18.2% |
Valuation Metrics
JPM leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 15.6x trailing earnings, JPM trades at a 84% valuation discount to ABBV's 94.8x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.78x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Market CapShares × price | $3.2B | $397.6B | $82M | $298.3B | $875.8B | $355.2B |
| Enterprise ValueMkt cap + debt − cash | $3.1B | $461.4B | $71M | $334.3B | $1.47T | $390.4B |
| Trailing P/EPrice ÷ TTM EPS | -18.20x | 94.84x | -0.80x | 16.59x | 15.64x | 27.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.75x | — | 23.50x | 14.08x | 25.24x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.78x | 1.20x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 16.34x | — | 11.40x | 18.11x | 26.36x |
| Price / SalesMarket cap ÷ Revenue | 1567.68x | 6.50x | — | 4.59x | 3.13x | 7.41x |
| Price / BookPrice ÷ Book value/share | 5.86x | — | 3.14x | 5.75x | 2.42x | 10.39x |
| Price / FCFMarket cap ÷ FCF | — | 22.32x | — | 24.13x | 8.68x | 67.07x |
Profitability & Efficiency
Evenly matched — DNTH and MRK each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-124 for ALXO. DNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ALXO's 2/9, reflecting strong financial health.
| Metric | ||||||
|---|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -1.8% | +62.1% | -124.1% | +36.1% | +15.9% | +41.1% |
| ROA (TTM)Return on assets | -1.7% | +3.1% | -85.6% | +14.6% | +1.3% | +13.1% |
| ROICReturn on invested capital | -34.4% | +23.9% | -122.0% | +22.0% | +4.5% | +15.8% |
| ROCEReturn on capital employed | -41.6% | +21.5% | -127.0% | +23.8% | +8.9% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 6 | 2 | 4 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.00x | — | 0.20x | 0.96x | 2.60x | 1.33x |
| Net DebtTotal debt minus cash | -$50M | $63.8B | -$11M | $36.0B | $599.0B | $35.2B |
| Cash & Equiv.Liquid assets | $51M | $5.2B | $16M | $14.6B | $343.3B | $10.3B |
| Total DebtShort + long-term debt | $1M | $69.1B | $5M | $50.5B | $942.4B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | — | 3.28x | -58.09x | 19.68x | 0.74x | 10.70x |
Total Returns (Dividends Reinvested)
DNTH leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $22,106 today (with dividends reinvested), compared to $255 for ALXO. Over the past 12 months, DNTH leads with a +321.9% total return vs KO's +17.4%. The 3-year compound annual growth rate (CAGR) favors DNTH at 89.0% vs ALXO's -44.2% — a key indicator of consistent wealth creation.
| Metric | ||||||
|---|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +92.7% | -0.5% | +32.2% | +14.3% | -2.8% | +20.2% |
| 1-Year ReturnPast 12 months | +321.9% | +20.9% | +177.1% | +54.5% | +19.1% | +17.4% |
| 3-Year ReturnCumulative with dividends | +574.8% | +77.1% | -82.6% | +18.6% | +133.1% | +46.9% |
| 5-Year ReturnCumulative with dividends | -58.7% | +121.1% | -97.5% | +78.0% | +110.0% | +63.6% |
| 10-Year ReturnCumulative with dividends | -67.1% | +357.3% | -94.9% | +172.8% | +454.4% | +120.9% |
| CAGR (3Y)Annualised 3-year return | +89.0% | +21.0% | -44.2% | +5.8% | +32.6% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than ALXO's 1.49 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs ALXO's 57.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.29x | 0.15x | 1.49x | 0.34x | 0.95x | -0.15x |
| 52-Week HighHighest price in past year | $96.50 | $244.81 | $2.66 | $125.14 | $337.25 | $84.04 |
| 52-Week LowLowest price in past year | $16.64 | $181.73 | $0.40 | $76.66 | $262.71 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +79.2% | +91.8% | +57.1% | +96.5% | +93.0% | +98.2% |
| RSI (14)Momentum oscillator 0–100 | 37.8 | 63.2 | 27.9 | 55.4 | 54.8 | 65.7 |
| Avg Volume (50D)Average daily shares traded | 674K | 4.6M | 1.1M | 7.1M | 7.0M | 12.6M |
Analyst Outlook
Evenly matched — ABBV and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: DNTH as "Buy", ABBV as "Buy", ALXO as "Buy", MRK as "Buy", JPM as "Buy", KO as "Buy". Consensus price targets imply 163.2% upside for ALXO (target: $4) vs 4.6% for KO (target: $86). For income investors, ABBV offers the higher dividend yield at 2.92% vs JPM's 1.90%.
| Metric | ||||||
|---|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $111.91 | $257.54 | $4.00 | $130.69 | $338.78 | $86.29 |
| # AnalystsCovering analysts | 10 | 41 | 7 | 37 | 61 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +2.9% | — | +2.7% | +1.9% | +2.5% |
| Dividend StreakConsecutive years of raises | — | 43 | — | 15 | 15 | 56 |
| Dividend / ShareAnnual DPS | — | $6.57 | — | $3.26 | $5.95 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.2% | 0.0% | +1.7% | +3.9% | +0.2% |
MRK leads in 1 of 6 categories (Income & Cash Flow). JPM leads in 1 (Valuation Metrics). 2 tied.
DNTH vs ABBV vs ALXO vs MRK vs JPM vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is DNTH or ABBV or ALXO or MRK or JPM or KO a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -67. 3% for Dianthus Therapeutics, Inc. (DNTH). JPMorgan Chase & Co. (JPM) offers the better valuation at 15. 6x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Dianthus Therapeutics, Inc. (DNTH) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — DNTH or ABBV or ALXO or MRK or JPM or KO?
On trailing P/E, JPMorgan Chase & Co.
(JPM) is the cheapest at 15. 6x versus AbbVie Inc. at 94. 8x. On forward P/E, JPMorgan Chase & Co. is actually cheaper at 14. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 1. 08x versus The Coca-Cola Company's 2. 26x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — DNTH or ABBV or ALXO or MRK or JPM or KO?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +121. 1%, compared to -97. 5% for ALX Oncology Holdings Inc. (ALXO). Over 10 years, the gap is even starker: JPM returned +454. 4% versus ALXO's -94. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — DNTH or ABBV or ALXO or MRK or JPM or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
15β versus ALX Oncology Holdings Inc. 's 1. 49β — meaning ALXO is approximately -1109% more volatile than KO relative to the S&P 500. On balance sheet safety, Dianthus Therapeutics, Inc. (DNTH) carries a lower debt/equity ratio of 0% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — DNTH or ABBV or ALXO or MRK or JPM or KO?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -67. 3% for Dianthus Therapeutics, Inc. (DNTH). On earnings-per-share growth, the picture is similar: ALX Oncology Holdings Inc. grew EPS 26. 4% year-over-year, compared to -64. 7% for Dianthus Therapeutics, Inc.. Over a 3-year CAGR, KO leads at 3. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — DNTH or ABBV or ALXO or MRK or JPM or KO?
Merck & Co.
, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus -79. 7% for Dianthus Therapeutics, Inc. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus -87. 4% for DNTH. At the gross margin level — before operating expenses — DNTH leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is DNTH or ABBV or ALXO or MRK or JPM or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 1. 08x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, JPMorgan Chase & Co. (JPM) trades at 14. 1x forward P/E versus 25. 2x for The Coca-Cola Company — 11. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ALXO: 163. 2% to $4. 00.
08Which pays a better dividend — DNTH or ABBV or ALXO or MRK or JPM or KO?
In this comparison, ABBV (2.
9% yield), MRK (2. 7% yield), KO (2. 5% yield), JPM (1. 9% yield) pay a dividend. DNTH, ALXO do not pay a meaningful dividend and should not be held primarily for income.
09Is DNTH or ABBV or ALXO or MRK or JPM or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
15), 2. 5% yield, +120. 9% 10Y return). Both have compounded well over 10 years (KO: +120. 9%, ALXO: -94. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between DNTH and ABBV and ALXO and MRK and JPM and KO?
These companies operate in different sectors (DNTH (Healthcare) and ABBV (Healthcare) and ALXO (Healthcare) and MRK (Healthcare) and JPM (Financial Services) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: DNTH is a small-cap quality compounder stock; ABBV is a large-cap quality compounder stock; ALXO is a small-cap quality compounder stock; MRK is a large-cap deep-value stock; JPM is a large-cap deep-value stock; KO is a large-cap quality compounder stock. ABBV, MRK, JPM, KO pay a dividend while DNTH, ALXO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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