Biotechnology
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Side-by-side financial analysisStock Comparison
MAZE vs ACMR vs ICHR vs RARE vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Semiconductors
Semiconductors
Biotechnology
Beverages - Non-Alcoholic
MAZE vs ACMR vs ICHR vs RARE vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Semiconductors | Semiconductors | Biotechnology | Beverages - Non-Alcoholic |
| Market Cap | $1.33B | $6.22B | $3.02B | $2.39B | $355.61B |
| Revenue (TTM) | $20M | $960M | $959M | $669M | $49.28B |
| Net Income (TTM) | $-123M | $91M | $-51M | $-609M | $13.70B |
| Gross Margin | 92.0% | 44.2% | 11.3% | 83.6% | 61.7% |
| Operating Margin | -6.7% | 12.5% | -3.8% | -83.9% | 29.3% |
| Forward P/E | — | 47.1x | 63.0x | — | 25.3x |
| Total Debt | $23M | $303M | $186M | $1.28B | $45.49B |
| Cash & Equiv. | $189M | $766M | $98M | $434M | $10.27B |
MAZE vs ACMR vs ICHR vs RARE vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 25 | Jun 26 | Return |
|---|---|---|---|
| Maze Therapeutics, … (MAZE) | 100 | 150.8 | +50.8% |
| ACM Research, Inc. (ACMR) | 100 | 457.2 | +357.2% |
| Ichor Holdings, Ltd. (ICHR) | 100 | 316.1 | +216.1% |
| Ultragenyx Pharmace… (RARE) | 100 | 56.6 | -43.4% |
| The Coca-Cola Compa… (KO) | 100 | 130.2 | +30.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MAZE vs ACMR vs ICHR vs RARE vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MAZE is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 1.13, Low D/E 6.6%, current ratio 15.50x
- Beta 1.13, current ratio 15.50x
- Beta 1.13 vs ICHR's 3.97, lower leverage
ACMR ranks third and is worth considering specifically for long-term compounding and valuation efficiency.
- 49.2% 10Y total return vs ICHR's 7.9%
- PEG 1.33 vs KO's 2.26
- Better valuation composite
ICHR is the clearest fit if your priority is momentum.
- +361.7% vs RARE's -38.0%
RARE is the clearest fit if your priority is growth exposure.
- Rev growth 20.1%, EPS growth 7.3%, 3Y rev CAGR 22.8%
- 20.1% revenue growth vs MAZE's -100.0%
KO carries the broadest edge in this set and is the clearest fit for income & stability.
- Dividend streak 56 yrs, beta -0.20, yield 2.5%
- 27.8% margin vs MAZE's -6.1%
- 2.5% yield, 56-year raise streak, vs ACMR's 0.1%, (3 stocks pay no dividend)
- 13.1% ROA vs RARE's -45.8%, ROIC 15.8% vs -89.4%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 20.1% revenue growth vs MAZE's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 27.8% margin vs MAZE's -6.1% | |
| Stability / Safety | Beta 1.13 vs ICHR's 3.97, lower leverage | |
| Dividends | 2.5% yield, 56-year raise streak, vs ACMR's 0.1%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +361.7% vs RARE's -38.0% | |
| Efficiency (ROA) | 13.1% ROA vs RARE's -45.8%, ROIC 15.8% vs -89.4% |
MAZE vs ACMR vs ICHR vs RARE vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
MAZE vs ACMR vs ICHR vs RARE vs KO — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
KO leads in 3 of 6 categories
ACMR leads 1 • MAZE leads 0 • ICHR leads 0 • RARE leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
KO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
KO is the larger business by revenue, generating $49.3B annually — 2464.2x MAZE's $20M. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to MAZE's -6.1%. On growth, ACMR holds the edge at +34.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $20M | $960M | $959M | $669M | $49.3B |
| EBITDAEarnings before interest/tax | -$132M | $139M | -$11M | -$536M | $15.5B |
| Net IncomeAfter-tax profit | -$123M | $91M | -$51M | -$609M | $13.7B |
| Free Cash FlowCash after capex | -$122M | -$108M | -$17M | -$487M | $12.6B |
| Gross MarginGross profit ÷ Revenue | +92.0% | +44.2% | +11.3% | +83.6% | +61.7% |
| Operating MarginEBIT ÷ Revenue | -6.7% | +12.5% | -3.8% | -83.9% | +29.3% |
| Net MarginNet income ÷ Revenue | -6.1% | +9.5% | -5.3% | -91.0% | +27.8% |
| FCF MarginFCF ÷ Revenue | -6.1% | -11.3% | -1.7% | -72.8% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +34.2% | +4.7% | -2.4% | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +39.9% | -20.0% | +46.2% | -17.2% | +18.2% |
Valuation Metrics
Evenly matched — ICHR and KO each lead in 2 of 6 comparable metrics.
Valuation Metrics
At 27.2x trailing earnings, KO trades at a 60% valuation discount to ACMR's 68.6x P/E. Adjusting for growth (PEG ratio), ACMR offers better value at 1.93x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.3B | $6.2B | $3.0B | $2.4B | $355.6B |
| Enterprise ValueMkt cap + debt − cash | $1.2B | $5.8B | $3.1B | $3.2B | $390.8B |
| Trailing P/EPrice ÷ TTM EPS | -7.89x | 68.58x | -56.36x | -4.18x | 27.18x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 47.09x | 62.96x | — | 25.27x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.93x | — | — | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 45.79x | — | — | 26.39x |
| Price / SalesMarket cap ÷ Revenue | — | 6.90x | 3.18x | 3.56x | 7.42x |
| Price / BookPrice ÷ Book value/share | 2.91x | 3.28x | 4.48x | — | 10.40x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 67.15x |
Profitability & Efficiency
KO leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-6 for RARE. MAZE carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ACMR's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -36.6% | +5.1% | -7.5% | -6.1% | +41.1% |
| ROA (TTM)Return on assets | -31.8% | +3.4% | -5.2% | -45.8% | +13.1% |
| ROICReturn on invested capital | -99.4% | +7.0% | -3.9% | -89.4% | +15.8% |
| ROCEReturn on capital employed | -48.1% | +6.6% | -4.7% | -46.4% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 3 | 4 | 7 |
| Debt / EquityFinancial leverage | 0.07x | 0.16x | 0.28x | — | 1.33x |
| Net DebtTotal debt minus cash | -$166M | -$463M | $87M | $842M | $35.2B |
| Cash & Equiv.Liquid assets | $189M | $766M | $98M | $434M | $10.3B |
| Total DebtShort + long-term debt | $23M | $303M | $186M | $1.3B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -148.24x | 20.41x | -5.97x | -14.49x | 10.70x |
Total Returns (Dividends Reinvested)
ACMR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACMR five years ago would be worth $29,241 today (with dividends reinvested), compared to $2,367 for RARE. Over the past 12 months, ICHR leads with a +361.7% total return vs RARE's -38.0%. The 3-year compound annual growth rate (CAGR) favors ACMR at 107.4% vs RARE's -22.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -39.5% | +109.3% | +325.3% | +3.2% | +20.3% |
| 1-Year ReturnPast 12 months | +77.5% | +265.1% | +361.7% | -38.0% | +17.2% |
| 3-Year ReturnCumulative with dividends | +50.8% | +792.2% | +141.6% | -52.6% | +47.0% |
| 5-Year ReturnCumulative with dividends | +50.8% | +192.4% | +55.5% | -76.3% | +65.6% |
| 10-Year ReturnCumulative with dividends | +50.8% | +4924.1% | +788.4% | -59.4% | +121.1% |
| CAGR (3Y)Annualised 3-year return | +14.7% | +107.4% | +34.2% | -22.0% | +13.7% |
Risk & Volatility
Evenly matched — ICHR and KO each lead in 1 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ICHR's 3.97 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ICHR currently trades 98.5% from its 52-week high vs MAZE's 44.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.13x | 3.46x | 3.97x | 1.43x | -0.20x |
| 52-Week HighHighest price in past year | $53.65 | $99.45 | $88.15 | $42.37 | $84.04 |
| 52-Week LowLowest price in past year | $9.83 | $23.03 | $13.12 | $18.29 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +44.8% | +94.5% | +98.5% | +57.5% | +98.3% |
| RSI (14)Momentum oscillator 0–100 | 40.2 | 64.2 | 65.4 | 53.2 | 60.6 |
| Avg Volume (50D)Average daily shares traded | 642K | 1.5M | 990K | 1.5M | 12.7M |
Analyst Outlook
KO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: MAZE as "Buy", ACMR as "Buy", ICHR as "Buy", RARE as "Buy", KO as "Buy". Consensus price targets imply 163.0% upside for MAZE (target: $63) vs -37.1% for ICHR (target: $55). For income investors, KO offers the higher dividend yield at 2.46% vs ACMR's 0.12%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $63.25 | $87.50 | $54.60 | $48.36 | $86.13 |
| # AnalystsCovering analysts | 6 | 10 | 14 | 33 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.1% | — | — | +2.5% |
| Dividend StreakConsecutive years of raises | — | 3 | 1 | 1 | 56 |
| Dividend / ShareAnnual DPS | — | $0.11 | — | — | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.1% | 0.0% | 0.0% | +0.2% |
KO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ACMR leads in 1 (Total Returns). 2 tied.
MAZE vs ACMR vs ICHR vs RARE vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MAZE or ACMR or ICHR or RARE or KO a better buy right now?
For growth investors, Ultragenyx Pharmaceutical Inc.
(RARE) is the stronger pick with 20. 1% revenue growth year-over-year, versus -100. 0% for Maze Therapeutics, Inc. (MAZE). The Coca-Cola Company (KO) offers the better valuation at 27. 2x trailing P/E (25. 3x forward), making it the more compelling value choice. Analysts rate Maze Therapeutics, Inc. (MAZE) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MAZE or ACMR or ICHR or RARE or KO?
On trailing P/E, The Coca-Cola Company (KO) is the cheapest at 27.
2x versus ACM Research, Inc. at 68. 6x. On forward P/E, The Coca-Cola Company is actually cheaper at 25. 3x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: ACM Research, Inc. wins at 1. 33x versus The Coca-Cola Company's 2. 26x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — MAZE or ACMR or ICHR or RARE or KO?
Over the past 5 years, ACM Research, Inc.
(ACMR) delivered a total return of +192. 4%, compared to -76. 3% for Ultragenyx Pharmaceutical Inc. (RARE). Over 10 years, the gap is even starker: ACMR returned +49. 2% versus RARE's -59. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MAZE or ACMR or ICHR or RARE or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Ichor Holdings, Ltd. 's 3. 97β — meaning ICHR is approximately -2084% more volatile than KO relative to the S&P 500. On balance sheet safety, Maze Therapeutics, Inc. (MAZE) carries a lower debt/equity ratio of 7% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.
05Which is growing faster — MAZE or ACMR or ICHR or RARE or KO?
By revenue growth (latest reported year), Ultragenyx Pharmaceutical Inc.
(RARE) is pulling ahead at 20. 1% versus -100. 0% for Maze Therapeutics, Inc. (MAZE). On earnings-per-share growth, the picture is similar: The Coca-Cola Company grew EPS 23. 6% year-over-year, compared to -40. 2% for Maze Therapeutics, Inc.. Over a 3-year CAGR, ACMR leads at 32. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MAZE or ACMR or ICHR or RARE or KO?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -612. 7% for Maze Therapeutics, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -670. 3% for MAZE. At the gross margin level — before operating expenses — MAZE leads at 92. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MAZE or ACMR or ICHR or RARE or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, ACM Research, Inc. (ACMR) is the more undervalued stock at a PEG of 1. 33x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, The Coca-Cola Company (KO) trades at 25. 3x forward P/E versus 63. 0x for Ichor Holdings, Ltd. — 37. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MAZE: 163. 0% to $63. 25.
08Which pays a better dividend — MAZE or ACMR or ICHR or RARE or KO?
In this comparison, KO (2.
5% yield), ACMR (0. 1% yield) pay a dividend. MAZE, ICHR, RARE do not pay a meaningful dividend and should not be held primarily for income.
09Is MAZE or ACMR or ICHR or RARE or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). ACM Research, Inc. (ACMR) carries a higher beta of 3. 46 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, ACMR: +49. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MAZE and ACMR and ICHR and RARE and KO?
These companies operate in different sectors (MAZE (Healthcare) and ACMR (Technology) and ICHR (Technology) and RARE (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: MAZE is a small-cap quality compounder stock; ACMR is a small-cap high-growth stock; ICHR is a small-cap quality compounder stock; RARE is a small-cap high-growth stock; KO is a large-cap quality compounder stock. KO pays a dividend while MAZE, ACMR, ICHR, RARE do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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