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MAZEMaze Therapeutics, Inc.
$28.43$1.6B
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MAZE logoMaze Therapeutics, Inc.(MAZE)Earnings, Financials & Key Ratios

MAZE•NASDAQ
$28.43
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryMetabolic and Obesity Therapies
AboutMaze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of renal, cardiovascular, related metabolic diseases, and obesity in the United States. Its lead programs includes MZE829, an oral small molecule inhibitor of apolipoprotein L1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor of the solute transporter SLC6A19, which is in phase I clinical trial for the treatment of chronic kidney disease. Maze Therapeutics, Inc. was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.Show more
  • Revenue$0-100.0%
  • EBITDA-$140M-330.8%
  • Net Income-$131M-351.0%
  • EPS (Diluted)-3.05-4020.3%
  • ROE-47.52%-194.1%

MAZE Price & Volume

Maze Therapeutics, Inc. (MAZE) stock price & volume — 10-year historical chart

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Clinical Development Costs Outpace Erratic Revenue Streams

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical Trial Funding Gap
"Maze Therapeutics faces a precarious outlook as its reliance on sporadic milestone payments, such as the $20.0 million recognized in 2026Q1, fails to offset the substantial R&D expenditures required to sustain its Compass platform. The loss of key strategic partnerships has significantly increased the firm's reliance on its $198.8 million cash reserve, heightening the probability of future dilutive equity financing. Investors should monitor the company's ability to achieve clinical milestones without the support of a stable, recurring commercial revenue model."

Verdict Logic

the company's fundamental instability is underscored by a persistent free cash flow burn of $39.2 million in 2026Q1 and the absence of a sustainable, recurring revenue stream to support its long-term clinical development.

MAZE Growth Metrics

Maze Therapeutics, Inc. (MAZE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-88.06%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-335.93%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-4396.88%

Return on Capital

10 Years-49.77%
5 Years-49.77%
3 Years-37.71%
Last Year-48.08%

MAZE Recent Earnings

Maze Therapeutics, Inc. (MAZE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/11 qtrs (50%)●Beat Revenue 1/11 qtrs (100%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.45-4.7%
$0.43
Rev
$20M+88.2%
$11M
Q2 2026
Mar 25, 2026
Metric
Actual
Est
EPS
$0.65+11.0%
$0.73
Rev
—
$375,000
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.66+10.8%
$0.74
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.77+2.5%
$0.79
Rev
—
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.45vs $0.43-4.7%
$20Mvs $11M+88.2%
Q2 2026Mar 25, 2026
$0.65vs $0.73+11.0%
—vs $375,000
Q4 2025Nov 6, 2025
$0.66vs $0.74+10.8%
—
Q3 2025Aug 12, 2025
$0.77vs $0.79+2.5%
—vs $3M
Based on last 11 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Maze Therapeutics, Inc. (MAZE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MAZE logoMAZEMaze Therapeutics, Inc.Current
$28.43$1.57B-9.32-100%—-47.52%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$30.77$3.03B-5.2820.13%-91.03%——
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
ACMR logoACMRACM Research, Inc.
$104.50$6.92B76.2815.24%9.48%5.13%—
BEAM logoBEAMBeam Therapeutics Inc.
$34.81$3.58B-42.98120.01%-49.17%-5.89%—
NTLA logoNTLAIntellia Therapeutics, Inc.
$16.68$1.87B-4.3816.92%-597.04%-57.27%—

Compare MAZE vs Peers

Maze Therapeutics, Inc. (MAZE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RARE

Most directly comparable listed peer for MAZE.

Scale Benchmark

vs TMO

Larger-name benchmark to compare MAZE against a more recognizable public peer.

Peer Set

Compare Top 5

vs RARE, FOLD, ACMR, BEAM

MAZE SEC Filings & Documents

Maze Therapeutics, Inc. (MAZE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Apr 22, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

4
FY 2026

May 12, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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MAZE Frequently Asked Questions

Maze Therapeutics, Inc. (MAZE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Maze Therapeutics, Inc.'s revenue?

Maze Therapeutics, Inc. (MAZE) reported $20.0M in revenue for fiscal year 2025.

How fast is Maze Therapeutics, Inc. growing?

Maze Therapeutics, Inc. (MAZE) saw revenue decline by 100.0% over the past year.

Is MAZE profitable?

Maze Therapeutics, Inc. (MAZE) reported a net loss of $122.5M for fiscal year 2025.

Dividend & Returns
What is MAZE's return on equity?

Maze Therapeutics, Inc. (MAZE) has a return on equity (ROE) of -47.5%. Negative ROE indicates the company is unprofitable.

What is Maze Therapeutics, Inc.'s free cash flow?

Maze Therapeutics, Inc. (MAZE) had negative free cash flow of $122.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MAZE back in 2022?

Total return calculator · dividends reinvested · 4+ years of data

See returns →