Biotechnology
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Side-by-side financial analysisStock Comparison
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Biotechnology
Biotechnology
Banks - Diversified
Beverages - Non-Alcoholic
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||||
|---|---|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Biotechnology | Biotechnology | Banks - Diversified | Beverages - Non-Alcoholic |
| Market Cap | $54M | $1.07T | $194.99B | $1.46B | $134M | $896.00B | $355.61B |
| Revenue (TTM) | $0.00 | $72.25B | $327.80B | $286M | $79M | $280.33B | $49.28B |
| Net Income (TTM) | $-47M | $25.27B | $121.96B | $-354M | $-137M | $57.05B | $13.70B |
| Gross Margin | — | 83.5% | 81.8% | 114.5% | 90.7% | 60.0% | 61.7% |
| Operating Margin | — | 45.9% | 45.3% | -127.2% | -149.6% | 25.9% | 29.3% |
| Forward P/E | — | 30.9x | 2.0x | — | — | 14.4x | 25.3x |
| Total Debt | $85M | $42.50B | $130.96B | $48M | $439M | $942.38B | $45.49B |
| Cash & Equiv. | $7M | $7.16B | $26.46B | $163M | $261M | $343.34B | $10.27B |
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Mar 21 | Jun 26 | Return |
|---|---|---|---|
| Instil Bio, Inc. (TIL) | 100 | 1.6 | -98.4% |
| Eli Lilly and Compa… (LLY) | 100 | 606.5 | +506.5% |
| Novo Nordisk A/S (NVO) | 100 | 130.2 | +30.2% |
| Iovance Biotherapeu… (IOVA) | 100 | 12.9 | -87.1% |
| ADC Therapeutics S.… (ADCT) | 100 | 4.3 | -95.7% |
| JPMorgan Chase & Co. (JPM) | 100 | 210.7 | +110.7% |
| The Coca-Cola Compa… (KO) | 100 | 156.7 | +56.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TIL lags the leaders in this set but could rank higher in a more targeted comparison.
LLY ranks third and is worth considering specifically for growth exposure and long-term compounding.
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 14.8% 10Y total return vs JPM's 465.8%
- Lower volatility, beta 0.53, current ratio 1.58x
- Beta 0.53 vs ADCT's 1.84
NVO carries the broadest edge in this set and is the clearest fit for income & stability and valuation efficiency.
- Dividend streak 1 yrs, beta 1.47, yield 4.1%
- PEG 0.10 vs KO's 2.26
- Beta 1.47, yield 4.1%, current ratio 0.80x
- Lower P/E (2.0x vs 25.3x), PEG 0.10 vs 2.26
- 37.2% margin vs ADCT's -173.0%
IOVA is the #2 pick in this set and the best alternative if growth and momentum is your priority.
- 60.6% revenue growth vs KO's 1.9%
- +76.6% vs TIL's -78.9%
Among these 7 stocks, ADCT doesn't own a clear edge in any measured category.
JPM doesn't hold a clear category lead here; it's more of a secondary option in this specific comparison.
In this particular matchup, KO is outpaced on most metrics by others in the set.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 60.6% revenue growth vs KO's 1.9% | |
| Value | Lower P/E (2.0x vs 25.3x), PEG 0.10 vs 2.26 | |
| Quality / Margins | 37.2% margin vs ADCT's -173.0% | |
| Stability / Safety | Beta 0.53 vs ADCT's 1.84 | |
| Dividends | 4.1% yield, 1-year raise streak, vs KO's 2.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +76.6% vs TIL's -78.9% | |
| Efficiency (ROA) | 23.3% ROA vs ADCT's -44.7% |
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO — Financial Metrics
Side-by-side numbers across 7 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 3 of 6 categories
NVO leads 1 • KO leads 1 • TIL leads 0 • IOVA leads 0 • ADCT leads 0 • JPM leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVO and TIL operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to ADCT's -173.0%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $72.2B | $327.8B | $286M | $79M | $280.3B | $49.3B |
| EBITDAEarnings before interest/tax | -$54M | $34.7B | $170.2B | -$330M | -$117M | $81.4B | $15.5B |
| Net IncomeAfter-tax profit | -$47M | $25.3B | $122.0B | -$354M | -$137M | $57.0B | $13.7B |
| Free Cash FlowCash after capex | -$34M | $13.6B | $31.0B | -$305M | -$115M | $100.9B | $12.6B |
| Gross MarginGross profit ÷ Revenue | — | +83.5% | +81.8% | +114.5% | +90.7% | +60.0% | +61.7% |
| Operating MarginEBIT ÷ Revenue | — | +45.9% | +45.3% | -127.2% | -149.6% | +25.9% | +29.3% |
| Net MarginNet income ÷ Revenue | — | +35.0% | +37.2% | -123.9% | -173.0% | +20.4% | +27.8% |
| FCF MarginFCF ÷ Revenue | — | +18.8% | +9.5% | -106.8% | -144.7% | +36.0% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% | +24.0% | +44.8% | -9.5% | — | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +85.6% | +169.9% | +67.1% | +47.2% | +41.7% | +16.0% | +18.2% |
Valuation Metrics
NVO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 12.3x trailing earnings, NVO trades at a 75% valuation discount to LLY's 49.4x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.60x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Market CapShares × price | $54M | $1.07T | $195.0B | $1.5B | $134M | $896.0B | $355.6B |
| Enterprise ValueMkt cap + debt − cash | $132M | $1.11T | $211.2B | $1.3B | $311M | $1.50T | $390.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.74x | 49.37x | 12.31x | -3.74x | -0.94x | 16.00x | 27.18x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 30.95x | 2.03x | — | — | 14.40x | 25.27x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.71x | 0.60x | — | — | 0.90x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 35.38x | 9.12x | — | — | 18.36x | 26.39x |
| Price / SalesMarket cap ÷ Revenue | — | 16.42x | 4.08x | 5.54x | 1.64x | 3.20x | 7.42x |
| Price / BookPrice ÷ Book value/share | 0.46x | 38.34x | 6.50x | 2.09x | — | 2.47x | 10.40x |
| Price / FCFMarket cap ÷ FCF | — | 119.31x | 43.48x | — | — | 8.88x | 67.15x |
Profitability & Efficiency
LLY leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-50 for IOVA. IOVA carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs TIL's 2/9, reflecting strong financial health.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -39.8% | +101.2% | +66.4% | -50.2% | — | +15.9% | +41.1% |
| ROA (TTM)Return on assets | -22.4% | +22.7% | +23.3% | -38.8% | -44.7% | +1.3% | +13.1% |
| ROICReturn on invested capital | -18.0% | +41.8% | +36.2% | -48.9% | — | +4.5% | +15.8% |
| ROCEReturn on capital employed | -23.3% | +46.6% | +44.4% | -51.6% | -43.8% | +8.9% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 8 | 5 | 5 | 4 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.75x | 1.60x | 0.67x | 0.07x | — | 2.60x | 1.33x |
| Net DebtTotal debt minus cash | $79M | $35.3B | $104.5B | -$115M | $178M | $599.0B | $35.2B |
| Cash & Equiv.Liquid assets | $7M | $7.2B | $26.5B | $163M | $261M | $343.3B | $10.3B |
| Total DebtShort + long-term debt | $85M | $42.5B | $131.0B | $48M | $439M | $942.4B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -8.24x | 35.68x | 18.90x | — | -1.72x | 0.74x | 10.70x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,207 today (with dividends reinvested), compared to $239 for TIL. Over the past 12 months, IOVA leads with a +76.6% total return vs TIL's -78.9%. The 3-year compound annual growth rate (CAGR) favors LLY at 37.2% vs ADCT's -25.4% — a key indicator of consistent wealth creation.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -29.7% | +5.2% | -13.9% | +61.9% | -70.2% | -0.5% | +20.3% |
| 1-Year ReturnPast 12 months | -78.9% | +40.3% | -43.6% | +76.6% | -71.4% | +21.8% | +17.2% |
| 3-Year ReturnCumulative with dividends | -29.8% | +158.2% | -38.6% | -51.9% | -58.5% | +138.2% | +47.0% |
| 5-Year ReturnCumulative with dividends | -97.6% | +412.1% | +19.3% | -82.9% | -95.5% | +118.2% | +65.6% |
| 10-Year ReturnCumulative with dividends | -98.5% | +1484.6% | +95.7% | -44.6% | -96.5% | +465.8% | +121.1% |
| CAGR (3Y)Annualised 3-year return | -11.1% | +37.2% | -15.0% | -21.7% | -25.4% | +33.6% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than ADCT's 1.84 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs TIL's 20.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.55x | 0.53x | 1.47x | 1.80x | 1.84x | 0.94x | -0.20x |
| 52-Week HighHighest price in past year | $38.50 | $1182.73 | $81.44 | $5.63 | $4.97 | $337.25 | $84.04 |
| 52-Week LowLowest price in past year | $5.67 | $623.78 | $35.12 | $1.66 | $0.78 | $262.71 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +20.6% | +95.8% | +53.9% | +72.5% | +21.1% | +95.1% | +98.3% |
| RSI (14)Momentum oscillator 0–100 | 40.9 | 70.0 | 52.4 | 51.6 | 14.9 | 59.1 | 60.6 |
| Avg Volume (50D)Average daily shares traded | 26K | 2.6M | 14.8M | 14.4M | 1.8M | 7.0M | 12.7M |
Analyst Outlook
Evenly matched — NVO and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: LLY as "Buy", NVO as "Buy", IOVA as "Buy", ADCT as "Hold", JPM as "Buy", KO as "Buy". Consensus price targets imply 233.3% upside for ADCT (target: $4) vs -2.0% for IOVA (target: $4). For income investors, NVO offers the higher dividend yield at 4.10% vs LLY's 0.53%.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $1268.94 | $45.00 | $4.00 | $3.50 | $339.75 | $86.13 |
| # AnalystsCovering analysts | — | 45 | 39 | 20 | 12 | 61 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% | +4.1% | — | — | +1.9% | +2.5% |
| Dividend StreakConsecutive years of raises | — | 11 | 1 | 1 | — | 15 | 56 |
| Dividend / ShareAnnual DPS | — | $6.00 | $11.64 | — | — | $5.95 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | +0.1% | 0.0% | 0.0% | +3.9% | +0.2% |
LLY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVO leads in 1 (Valuation Metrics). 1 tied.
TIL vs LLY vs NVO vs IOVA vs ADCT vs JPM vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TIL or LLY or NVO or IOVA or ADCT or JPM or KO a better buy right now?
For growth investors, Iovance Biotherapeutics, Inc.
(IOVA) is the stronger pick with 60. 6% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). Novo Nordisk A/S (NVO) offers the better valuation at 12. 3x trailing P/E (2. 0x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.
3x versus Eli Lilly and Company at 49. 4x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 0x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +412.
1%, compared to -97. 6% for Instil Bio, Inc. (TIL). Over 10 years, the gap is even starker: LLY returned +1485% versus TIL's -98. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus ADC Therapeutics S. A. 's 1. 84β — meaning ADCT is approximately -1018% more volatile than KO relative to the S&P 500. On balance sheet safety, Iovance Biotherapeutics, Inc. (IOVA) carries a lower debt/equity ratio of 7% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
By revenue growth (latest reported year), Iovance Biotherapeutics, Inc.
(IOVA) is pulling ahead at 60. 6% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to 1. 5% for JPMorgan Chase & Co.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
Novo Nordisk A/S (NVO) is the more profitable company, earning 33.
1% net margin versus -175. 3% for ADC Therapeutics S. A. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus -153. 1% for IOVA. At the gross margin level — before operating expenses — IOVA leads at 97. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TIL or LLY or NVO or IOVA or ADCT or JPM or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 0x forward P/E versus 30. 9x for Eli Lilly and Company — 28. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADCT: 233. 3% to $3. 50.
08Which pays a better dividend — TIL or LLY or NVO or IOVA or ADCT or JPM or KO?
In this comparison, NVO (4.
1% yield), KO (2. 5% yield), JPM (1. 9% yield), LLY (0. 5% yield) pay a dividend. TIL, IOVA, ADCT do not pay a meaningful dividend and should not be held primarily for income.
09Is TIL or LLY or NVO or IOVA or ADCT or JPM or KO better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
53), 0. 5% yield, +1485% 10Y return). ADC Therapeutics S. A. (ADCT) carries a higher beta of 1. 84 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LLY: +1485%, ADCT: -96. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TIL and LLY and NVO and IOVA and ADCT and JPM and KO?
These companies operate in different sectors (TIL (Healthcare) and LLY (Healthcare) and NVO (Healthcare) and IOVA (Healthcare) and ADCT (Healthcare) and JPM (Financial Services) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: TIL is a small-cap quality compounder stock; LLY is a mega-cap high-growth stock; NVO is a mid-cap deep-value stock; IOVA is a small-cap high-growth stock; ADCT is a small-cap quality compounder stock; JPM is a large-cap deep-value stock; KO is a large-cap quality compounder stock. LLY, NVO, JPM, KO pay a dividend while TIL, IOVA, ADCT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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