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LPTX logoLeap Therapeutics, Inc.(LPTX)Earnings, Financials & Key Ratios

LPTX•NASDAQ
11.0× P/E·Price updated May 29, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutLeap Therapeutics, Inc., a biopharmaceutical company, acquires and develops therapies for the treatment of cancer. Its lead clinical stage programs include DKN-01, a monoclonal antibody that inhibits Dickkopf-related protein 1, which is in multiple ongoing clinical trials for treating esophagogastric, hepatobiliary, gynecologic, and prostate cancers. Leap Therapeutics, Inc. has an option and license agreement with BeiGene, Ltd. to develop and commercialize DKN-01 in Asia (excluding Japan), Australia, and New Zealand. The company was formerly known as HealthCare Pharmaceuticals, Inc. and changed its name to Leap Therapeutics, Inc. in November 2015. Leap Therapeutics, Inc. was incorporated in 2011 and is based in Cambridge, Massachusetts.Show more
  • Revenue$0
  • EBITDA-$37M+47.8%
  • Net Income$5M+107.1%
  • EPS (Diluted)0.07+103.8%
  • ROE5.11%+103.6%

LPTX Key Insights

Leap Therapeutics, Inc. (LPTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 82 (top 18%)
  • ✓Trading at only 0.4x book value

✗Weaknesses

  • ✗Shares diluted 88.2% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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LPTX Price & Volume

Leap Therapeutics, Inc. (LPTX) stock price & volume — 10-year historical chart

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LPTX Growth Metrics

Leap Therapeutics, Inc. (LPTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-10.68%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM39.4%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM98.82%

Return on Capital

10 Years-90.07%
5 Years-90.56%
3 Years-112.05%
Last Year-37.73%

LPTX Peer Comparison

Leap Therapeutics, Inc. (LPTX) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IMVT logoIMVTImmunovant, Inc.Direct Competitor7.26B35.34-12.76-68.16%0.00
AGEN logoAGENAgenus Inc.Direct Competitor124.93M3.00-882.3510.37%52.16%
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor8.15B53.2219.2187.32%65.95%87.36%0.40
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.45B24.31-7.39-4.26%-156.36%-68.97%0.16
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
MGNX logoMGNXMacroGenics, Inc.Direct Competitor262.52M4.13-3.500.78%-44.79%-147.8%1.92
ZYME logoZYMEZymeworks Inc.Product Competitor1.7B23.14-21.4338.87%-126.33%-0.25%0.07
ALLO logoALLOAllogene Therapeutics, Inc.Product Competitor487.74M2.00-2.30-100%-56.45%0.26

Compare LPTX vs Peers

Leap Therapeutics, Inc. (LPTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for LPTX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare LPTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, AGEN, TGTX, RCUS

LPTX Income Statement

Leap Therapeutics, Inc. (LPTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
009.68M10.05M1.5M0000209K
Revenue Growth %
---3.85%-85.08%-100%----10.68%
Cost of Goods Sold
48K49K4.56M4.93M00427K0020.34M
COGS % of Revenue
--47.07%49.06%------
Gross Profit
-48K▲ 0%
-49K▼ 2.1%
5.12M▲ 10557.1%
5.12M▼ 0.1%
1.5M▼ 70.7%
0▼ 100.0%
-427K▲ 0%
0▲ 100.0%
0▲ 0%
-20.13M▲ 0%
Gross Margin %
--52.93%50.94%100%-----9631.58%
Gross Profit Growth %
-92%-2.08%10557.14%-0.06%-70.71%-100%-100%--
Operating Expenses
32.35M30M8.6M8.57M42.93M56.76M86.61M70.06M36.54M25.44M
OpEx % of Revenue
--88.84%85.22%2861.73%-----
Selling, General & Admin
9.85M8.92M7.44M7.02M10.77M11.8M13.38M12.85M10.87M12.52M
SG&A % of Revenue
--76.86%69.85%717.73%-----
Research & Development
22.5M21.07M1.13M1.43M32.16M44.97M73.23M57.21M25.67M32.01M
R&D % of Revenue
--11.63%14.19%2144%-----
Other Operating Expenses
0034K118K000001000K
Operating Income
-32.35M▲ 0%
-30.75M▲ 4.9%
-3.48M▲ 88.7%
-3.45M▲ 0.9%
-41.43M▼ 1102.1%
-56.76M▼ 37.0%
-87.04M▼ 53.3%
-70.06M▲ 19.5%
-36.54M▲ 47.8%
-29.97M▲ 0%
Operating Margin %
---35.91%-34.28%-2761.73%-----14338.28%
Operating Income Growth %
-17.55%4.95%88.7%0.86%-1102.15%-37.02%-53.34%19.51%47.84%-
EBITDA
-32.3M-30.7M-3.27M-3.24M-41.4M-56.75M-86.61M-70.05M-36.54M-29.72M
EBITDA Margin %
---33.78%-32.19%-2759.8%-----14221.05%
EBITDA Growth %
-17.49%4.96%89.35%1.04%-1179.26%-37.08%-52.63%19.12%47.84%70.01%
D&A (Non-Cash Add-back)
48K49K206K210K29K16K427K5K00
EBIT
-29.76M-23.1M-3.48M-3.44M-40.57M-54.4M-81.41M-70.06M-36.54M-29.72M
Net Interest Income
49K428K290K54K-32K871K4.03M3.13M892K549K
Interest Income
170K447K313K93K9K925K4.03M3.13M916K574K
Interest Expense
121K19K23K39K41K54K0024K25K
Other Income/Expense
2.47M7.63M30K59K815K2.31M5.63M3.09M46.62M-31.33M
Pretax Income
-29.88M▲ 0%
-23.12M▲ 22.6%
-3.45M▲ 85.1%
-3.39M▲ 1.7%
-40.61M▼ 1099.0%
-54.45M▼ 34.1%
-81.41M▼ 49.5%
-66.97M▲ 17.7%
10.08M▲ 115.0%
-56.77M▲ 0%
Pretax Margin %
---35.6%-33.69%-2707.4%-----27163.64%
Income Tax
-157K20K00-24K147K0585K5.25M137K
Effective Tax Rate %
0.53%-0.09%0%0%0.06%-0.27%0%-0.87%52.15%-0.24%
Net Income
-29.73M▲ 0%
-23.14M▲ 22.2%
-3.45M▲ 85.1%
-3.39M▲ 1.7%
-40.59M▼ 1098.3%
-54.6M▼ 34.5%
-81.41M▼ 49.1%
-67.56M▲ 17.0%
4.82M▲ 107.1%
-56.91M▲ 0%
Net Margin %
---35.6%-33.69%-2705.8%-----27229.19%
Net Income Growth %
-15.98%22.17%85.11%1.71%-1098.32%-34.52%-49.12%17.02%107.14%39.4%
Net Income (Continuing)
-29.73M-23.14M-3.45M-3.39M-40.59M-54.6M-81.41M-67.56M4.82M-79.58M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-32.35▲ 0%
-16.05▲ 50.4%
-14.57▲ 9.2%
-4.64▲ 68.2%
-4.73▼ 1.9%
-4.82▼ 1.9%
-3.98▲ 17.4%
-1.81▲ 54.5%
0.07▲ 103.8%
-0.34▲ 0%
EPS Growth %
-18.54%50.39%9.22%68.15%-1.94%-1.9%17.43%54.52%103.77%98.82%
EPS (Basic)
-32.45-16.36-14.57-4.64-4.73-4.82-3.98-1.810.07-
Diluted Shares Outstanding
918.86K1.44M2.26M5.93M8.58M11.32M20.45M37.55M70.67M168.1M
Basic Shares Outstanding
916.18K1.41M2.26M5.93M8.58M11.32M20.45M37.55M66.14M168.1M
Dividend Payout Ratio
----------

LPTX Balance Sheet

Leap Therapeutics, Inc. (LPTX) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
27.66M17.32M5.51M67.3M116.87M53.22M71.6M48.04M162.08M81.92M
Cash & Short-Term Investments
25.74M16.28M2.39M63.83M114.92M43.76M70.64M47.25M14.04M6.69M
Cash Only
25.74M16.28M2.39M63.83M114.92M20.99M70.64M47.25M14.04M6.69M
Short-Term Investments
0000022.76M0000
Accounts Receivable
1.74M836K2.04M2.01M1.19M1.36M771K704K148.01M74.47M
Days Sales Outstanding
--77.0773.09289.32----97.53K
Inventory
00645K980K01.4M0000
Days Inventory Outstanding
--51.6772.53------
Other Current Assets
0058K59K06.26M183K86K40K768K
Total Non-Current Assets
1.4M1.75M3.19M3.11M1.04M4.88M1.23M1.08M1.1M5.46M
Property, Plant & Equipment
135K86K2.74M2.73M495K371K262K262K38K38K
Fixed Asset Turnover
--3.54x3.69x3.03x----0.01x
Goodwill
0000000000
Intangible Assets
00138K130K025K0000
Long-Term Investments
00000150K00150K5.21M
Other Non-Current Assets
1.11M1.54M318K258K383K4.33M966K823K913K418K
Total Assets
29.06M▲ 0%
19.07M▼ 34.4%
8.7M▼ 54.4%
70.42M▲ 709.5%
117.91M▲ 67.4%
58.09M▼ 50.7%
72.83M▲ 25.4%
49.12M▼ 32.5%
163.18M▲ 232.2%
87.38M▲ 0%
Asset Turnover
--1.11x0.14x0.01x----0.00x
Asset Growth %
350.09%-34.37%-54.39%709.47%67.45%-50.73%25.36%-32.55%232.18%641.14%
Total Current Liabilities
6.08M6.45M1.57M1.8M9.99M3.12M12.68M14.08M4.56M3M
Accounts Payable
2.62M3.58M654K730K4.19M1.54M6.46M4.74M1.98M516K
Days Payables Outstanding
19.94K26.66K52.3954.02--5.53K--102.22
Short-Term Debt
0000000038K38K
Deferred Revenue (Current)
0000000000
Other Current Liabilities
000008K2.78M02.07M1.97M
Current Ratio
4.55x2.69x3.50x37.37x11.70x17.07x5.64x3.41x35.56x27.28x
Quick Ratio
4.55x2.69x3.09x36.83x11.70x16.62x5.64x3.41x35.56x27.28x
Cash Conversion Cycle
--76.3591.59-----97.43K
Total Non-Current Liabilities
11.86M3.45M1.4M1.21M37K331K005.12M0
Long-Term Debt
0000000000
Capital Lease Obligations
00769K524K37K256K000971K
Deferred Tax Liabilities
000000005.12M5.12M
Other Non-Current Liabilities
11.86M3.45M632K685K075K0000
Total Liabilities
17.95M9.9M2.98M3.01M10.02M3.45M12.68M14.08M9.68M3M
Total Debt
001M776K469K524K262K266K38K38K
Net Debt
-25.74M-16.28M-1.39M-63.05M-114.45M-20.47M-70.38M-46.98M-14M-6.65M
Debt / Equity
--0.18x0.01x0.00x0.01x0.00x0.01x0.00x0.00x
Debt / EBITDA
----------0.00x
Net Debt / EBITDA
---------0.22x
Interest Coverage
-245.98x-1215.74x-151.13x-88.13x-989.51x-1007.31x---1522.50x-1188.88x
Total Equity
11.12M▲ 0%
9.18M▼ 17.5%
5.72M▼ 37.6%
67.41M▲ 1077.8%
107.89M▲ 60.1%
54.64M▼ 49.4%
60.14M▲ 10.1%
35.05M▼ 41.7%
153.51M▲ 338.0%
84.38M▲ 0%
Equity Growth %
111.09%-17.47%-37.62%1077.81%60.06%-49.35%10.06%-41.72%337.99%939.32%
Book Value per Share
12.106.372.5311.3612.574.832.940.932.170.50
Total Shareholders' Equity
11.12M9.18M5.72M67.41M107.89M54.64M60.14M35.05M153.51M84.38M
Common Stock
12K15K69K142K88K142K26K38K84K94K
Retained Earnings
-130.4M-153.53M-87.94M-91.33M-263.57M-105.93M-399.58M-467.37M-462.55M-539.72M
Treasury Stock
0000000000
Accumulated OCI
-268K302K00-267K0106K-120K-95K-86K
Minority Interest
0000000000

LPTX Cash Flow Statement

Leap Therapeutics, Inc. (LPTX) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-22.14M-26.03M-26.9M-25.96M-35.16M-49.04M-43.75M-60.3M-43.9M-40.83M
Operating CF Margin %
---277.91%-258.2%-2343.8%-----
Operating CF Growth %
12.63%-17.6%-3.34%3.51%-35.44%-39.5%10.79%-37.82%27.19%123.24%
Net Income
-29.73M-23.14M-32.9M-27.51M-40.59M-54.6M-81.41M-67.56M4.82M-56.91M
Depreciation & Amortization
48K49K47K34K29K16K15K5K0775K
Stock-Based Compensation
5.6M3.47M3.89M2.62M3.48M5.18M5.13M5.5M4.9M9.67M
Deferred Taxes
-158K20K00379K0005.12M-5.12M
Other Non-Cash Items
-194K-7.3M729K-104K527K1.01M30.01M457K-50.19M123.1M
Working Capital Changes
2.29M871K1.33M-990K1.01M-651K2.51M1.29M-8.56M-1.97M
Change in Receivables
1.46M780K643K117K-1.16M-1.01M1.3M0149K42K
Change in Inventory
00001.16M00000
Change in Payables
1.09M368K003.9M0712K902K-10.42M-5.36M
Cash from Investing
-64K0-85K25K0048.97M0-97M-92.01M
Capital Expenditures
-64K0-100K00000-97M-102.99M
CapEx % of Revenue
--1.03%------49278.47%
Acquisitions
00000050.36M000
Investments
----------
Other Investing
-64K015K25K00-1.39M0015.98M
Cash from Financing
47.76M15.91M14.82M74M98.03M-210K-30K37.18M107.65M113.12M
Debt Issued (Net)
750K0000000-440K-437K
Equity Issued (Net)
49.16M15.03M15.25M75.5M97.22M0-29K40M108.09M113.18M
Dividends Paid
0000000000
Share Repurchases
000000-1K000
Other Financing
-2.15M872K-437K-1.51M813K-210K-1K-2.81M0376K
Net Change in Cash
24.94M▲ 0%
-9.45M▼ 137.9%
-12.39M▼ 31.1%
48.18M▲ 488.8%
62.84M▲ 30.4%
-49.42M▼ 178.6%
5.14M▲ 110.4%
-23.39M▼ 554.9%
-33.21M▼ 42.0%
-19.67M▲ 0%
Free Cash Flow
-22.2M▲ 0%
-26.03M▼ 17.3%
-27M▼ 3.7%
-25.96M▲ 3.9%
-35.16M▼ 35.4%
-49.04M▼ 39.5%
-43.75M▲ 10.8%
-60.3M▼ 37.8%
-43.9M▲ 27.2%
-79.65M▲ 0%
FCF Margin %
---278.95%-258.2%-2343.8%-----38108.13%
FCF Growth %
12.87%-17.26%-3.72%3.87%-35.44%-39.5%10.79%-37.82%27.19%-34.39%
FCF per Share
-24.16-18.06-11.96-4.38-4.10-4.33-2.14-1.61-0.62-0.47
FCF Conversion (FCF/Net Income)
0.74x1.13x7.81x7.66x0.87x0.90x0.54x0.89x-9.10x1.40x
Interest Paid
0000000000
Taxes Paid
0000000000

LPTX Key Ratios

Leap Therapeutics, Inc. (LPTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-267.4%-228.05%-46.26%-9.26%-46.31%-67.18%-141.86%-141.94%5.11%-46.86%
Return on Invested Capital (ROIC)
----59.48%--308.35%-545.53%--42.96%-21.22%
Gross Margin
--52.93%50.94%100%-----9631.58%
Net Margin
---35.6%-33.69%-2705.8%-----27229.19%
Debt / Equity
--0.18x0.01x0.00x0.01x0.00x0.01x0.00x0.00x
Interest Coverage
-245.98x-1215.74x-151.13x-88.13x-989.51x-1007.31x---1522.50x-1188.88x
FCF Conversion
0.74x1.13x7.81x7.66x0.87x0.90x0.54x0.89x-9.10x1.40x
Revenue Growth
---3.85%-85.08%-100%----10.68%
Related:LPTX Dividend History·LPTX Revenue History·LPTX Price History·LPTX P/E History·LPTX Financial Ratios·LPTX Institutional Holders

LPTX SEC Filings & Documents

Leap Therapeutics, Inc. (LPTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 26, 2026·SEC

Material company update

May 14, 2026·SEC

Material company update

Apr 10, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 16, 2026·SEC

FY 2025

Mar 26, 2025·SEC

FY 2024

Mar 18, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 14, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 14, 2025·SEC

LPTX Frequently Asked Questions

Leap Therapeutics, Inc. (LPTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Leap Therapeutics, Inc. (LPTX) reported $0.2M in revenue for fiscal year 2025.

Leap Therapeutics, Inc. (LPTX) grew revenue by 0.0% over the past year. Growth has been modest.

Leap Therapeutics, Inc. (LPTX) reported a net loss of $56.9M for fiscal year 2025.

Dividend & Returns

Leap Therapeutics, Inc. (LPTX) has a return on equity (ROE) of 5.1%. This is below average, suggesting room for improvement.

Leap Therapeutics, Inc. (LPTX) had negative free cash flow of $79.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in LPTX back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

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