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LPTX logoLeap Therapeutics, Inc.(LPTX)Earnings, Financials & Key Ratios

LPTX•NASDAQ
$0.77
$65M mkt cap·11.0× P/E·Price updated Apr 24, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutLeap Therapeutics, Inc., a biopharmaceutical company, acquires and develops therapies for the treatment of cancer. Its lead clinical stage programs include DKN-01, a monoclonal antibody that inhibits Dickkopf-related protein 1, which is in multiple ongoing clinical trials for treating esophagogastric, hepatobiliary, gynecologic, and prostate cancers. Leap Therapeutics, Inc. has an option and license agreement with BeiGene, Ltd. to develop and commercialize DKN-01 in Asia (excluding Japan), Australia, and New Zealand. The company was formerly known as HealthCare Pharmaceuticals, Inc. and changed its name to Leap Therapeutics, Inc. in November 2015. Leap Therapeutics, Inc. was incorporated in 2011 and is based in Cambridge, Massachusetts.Show more
  • Revenue$0
  • EBITDA-$41M+41.4%
  • Net Income$15M+122.7%
  • EPS (Diluted)0.07+103.9%
  • ROE16.26%+111.5%
  • ROIC-48.29%
  • Debt/Equity0.00-96.7%
Technical→

LPTX Key Insights

Leap Therapeutics, Inc. (LPTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 82 (top 18%)
  • ✓Trading at only 0.4x book value

✗Weaknesses

  • ✗Shares diluted 88.2% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

LPTX Price & Volume

Leap Therapeutics, Inc. (LPTX) stock price & volume — 10-year historical chart

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LPTX Growth Metrics

Leap Therapeutics, Inc. (LPTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-10.68%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM116.61%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM104.37%

Return on Capital

10 Years-90.59%
5 Years-91.49%
3 Years-113.61%
Last Year-42.41%

LPTX Peer Comparison

Leap Therapeutics, Inc. (LPTX) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IMVT logoIMVTImmunovant, Inc.Direct Competitor5.53B27.22-9.97-47.07%0.00
AGEN logoAGENAgenus Inc.Direct Competitor132.45M3.75-1102.9410.37%0.1%
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor6.87B43.0315.5387.32%65.95%87.36%0.40
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.5B24.80-7.54-4.26%-156.36%-68.97%0.16
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.69B83.37-8.57-43.89%-297.07%-399.1%1.66
MGNX logoMGNXMacroGenics, Inc.Direct Competitor186.16M2.94-2.490.78%-49.91%-120.2%0.66
ZYME logoZYMEZymeworks Inc.Product Competitor1.98B26.60-24.6338.87%-560.78%-107.52%0.07
ALLO logoALLOAllogene Therapeutics, Inc.Product Competitor520.77M2.27-2.61-100%-57.07%0.26

Compare LPTX vs Peers

Leap Therapeutics, Inc. (LPTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for LPTX.

Scale Benchmark

vs AZN

Larger-name benchmark to compare LPTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, AGEN, TGTX, RCUS

LPTX Income Statement

Leap Therapeutics, Inc. (LPTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue009.68M10.05M1.5M0000
Revenue Growth %---3.85%-85.08%-100%---
Cost of Goods Sold48K49K4.56M4.93M00427K00
COGS % of Revenue--47.07%49.06%-----
Gross Profit
-48K▲ 0%
-49K▼ 2.1%
5.12M▲ 10557.1%
5.12M▼ 0.1%
1.5M▼ 70.7%
0▼ 100.0%
-427K▲ 0%
0▲ 100.0%
0▲ 0%
Gross Margin %--52.93%50.94%100%----
Gross Profit Growth %-92%-2.08%10557.14%-0.06%-70.71%-100%-100%-
Operating Expenses32.35M30M8.6M8.57M42.93M56.76M86.61M70.06M41.07M
OpEx % of Revenue--88.84%85.22%2861.73%----
Selling, General & Admin9.85M8.92M7.44M7.02M10.77M11.8M13.38M12.85M10.87M
SG&A % of Revenue--76.86%69.85%717.73%----
Research & Development22.5M21.07M1.13M1.43M32.16M44.97M73.23M57.21M25.67M
R&D % of Revenue--11.63%14.19%2144%----
Other Operating Expenses0034K118K00004.53M
Operating Income
-32.35M▲ 0%
-30.75M▲ 4.9%
-3.48M▲ 88.7%
-3.45M▲ 0.9%
-41.43M▼ 1102.1%
-56.76M▼ 37.0%
-87.04M▼ 53.3%
-70.06M▲ 19.5%
-41.07M▲ 41.4%
Operating Margin %---35.91%-34.28%-2761.73%----
Operating Income Growth %-17.55%4.95%88.7%0.86%-1102.15%-37.02%-53.34%19.51%41.38%
EBITDA-32.3M-30.7M-3.27M-3.24M-41.4M-56.75M-86.61M-70.05M-41.07M
EBITDA Margin %---33.78%-32.19%-2759.8%----
EBITDA Growth %-17.49%4.96%89.35%1.04%-1179.26%-37.08%-52.63%19.12%41.38%
D&A (Non-Cash Add-back)48K49K206K210K29K16K427K5K0
EBIT-29.76M-23.1M-3.48M-3.44M-40.57M-54.4M-81.41M-70.06M0
Net Interest Income49K428K290K54K-32K871K4.03M3.13M0
Interest Income170K447K313K93K9K925K4.03M3.13M916K
Interest Expense121K19K23K39K41K54K00-24K
Other Income/Expense2.47M7.63M30K59K815K2.31M5.63M3.09M0
Pretax Income
-29.88M▲ 0%
-23.12M▲ 22.6%
-3.45M▲ 85.1%
-3.39M▲ 1.7%
-40.61M▼ 1099.0%
-54.45M▼ 34.1%
-81.41M▼ 49.5%
-66.97M▲ 17.7%
10.08M▲ 115.0%
Pretax Margin %---35.6%-33.69%-2707.4%----
Income Tax-157K20K00-24K147K0585K-5.25M
Effective Tax Rate %0.53%-0.09%0%0%0.06%-0.27%0%-0.87%-52.15%
Net Income
-29.73M▲ 0%
-23.14M▲ 22.2%
-3.45M▲ 85.1%
-3.39M▲ 1.7%
-40.59M▼ 1098.3%
-54.6M▼ 34.5%
-81.41M▼ 49.1%
-67.56M▲ 17.0%
15.33M▲ 122.7%
Net Margin %---35.6%-33.69%-2705.8%----
Net Income Growth %-15.98%22.17%85.11%1.71%-1098.32%-34.52%-49.12%17.02%122.7%
Net Income (Continuing)-29.73M-23.14M-3.45M-3.39M-40.59M-54.6M-81.41M-67.56M15.33M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-32.35▲ 0%
-16.05▲ 50.4%
-14.57▲ 9.2%
-4.64▲ 68.2%
-4.73▼ 1.9%
-4.82▼ 1.9%
-3.98▲ 17.4%
-1.81▲ 54.5%
0.07▲ 103.9%
EPS Growth %-18.54%50.39%9.22%68.15%-1.94%-1.9%17.43%54.52%103.87%
EPS (Basic)-32.45-16.36-14.57-4.64-4.73-4.82-3.98-1.810.07
Diluted Shares Outstanding918.86K1.44M2.26M5.93M8.58M11.32M20.45M37.55M70.67M
Basic Shares Outstanding916.18K1.41M2.26M5.93M8.58M11.32M20.45M37.55M66.14M
Dividend Payout Ratio---------

LPTX Balance Sheet

Leap Therapeutics, Inc. (LPTX) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets27.66M17.32M5.51M67.3M116.87M53.22M71.6M48.04M162.08M
Cash & Short-Term Investments25.74M16.28M2.39M63.83M114.92M43.76M70.64M47.25M14.04M
Cash Only25.74M16.28M2.39M63.83M114.92M20.99M70.64M47.25M14.04M
Short-Term Investments0000022.76M000
Accounts Receivable1.74M836K2.04M2.01M1.19M1.36M771K704K0
Days Sales Outstanding--77.0773.09289.32----
Inventory00645K980K01.4M000
Days Inventory Outstanding--51.6772.53-----
Other Current Assets0058K59K06.26M183K86K148.05M
Total Non-Current Assets1.4M1.75M3.19M3.11M1.04M4.88M1.23M1.08M1.1M
Property, Plant & Equipment135K86K2.74M2.73M495K371K262K262K38K
Fixed Asset Turnover--3.54x3.69x3.03x----
Goodwill000000000
Intangible Assets00138K130K025K000
Long-Term Investments00000150K000
Other Non-Current Assets1.11M1.54M318K258K383K4.33M966K823K1.06M
Total Assets
29.06M▲ 0%
19.07M▼ 34.4%
8.7M▼ 54.4%
70.42M▲ 709.5%
117.91M▲ 67.4%
58.09M▼ 50.7%
72.83M▲ 25.4%
49.12M▼ 32.5%
163.18M▲ 232.2%
Asset Turnover--1.11x0.14x0.01x----
Asset Growth %350.09%-34.37%-54.39%709.47%67.45%-50.73%25.36%-32.55%232.18%
Total Current Liabilities6.08M6.45M1.57M1.8M9.99M3.12M12.68M14.08M4.56M
Accounts Payable2.62M3.58M654K730K4.19M1.54M6.46M4.74M1.98M
Days Payables Outstanding19.94K26.66K52.3954.02--5.53K--
Short-Term Debt0000000038K
Deferred Revenue (Current)000000000
Other Current Liabilities000008K2.78M04.52M
Current Ratio4.55x2.69x3.50x37.37x11.70x17.07x5.64x3.41x35.56x
Quick Ratio4.55x2.69x3.09x36.83x11.70x16.62x5.64x3.41x35.56x
Cash Conversion Cycle--76.3591.59-----
Total Non-Current Liabilities11.86M3.45M1.4M1.21M37K331K005.12M
Long-Term Debt000000000
Capital Lease Obligations00769K524K37K256K000
Deferred Tax Liabilities000000005.12M
Other Non-Current Liabilities11.86M3.45M632K685K075K000
Total Liabilities17.95M9.9M2.98M3.01M10.02M3.45M12.68M14.08M9.68M
Total Debt001M776K469K524K262K266K38K
Net Debt-25.74M-16.28M-1.39M-63.05M-114.45M-20.47M-70.38M-46.98M-14M
Debt / Equity--0.18x0.01x0.00x0.01x0.00x0.01x0.00x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage-267.37x-1618.47x-151.13x-88.36x-1010.39x-1051.17x---
Total Equity
11.12M▲ 0%
9.18M▼ 17.5%
5.72M▼ 37.6%
67.41M▲ 1077.8%
107.89M▲ 60.1%
54.64M▼ 49.4%
60.14M▲ 10.1%
35.05M▼ 41.7%
153.51M▲ 338.0%
Equity Growth %111.09%-17.47%-37.62%1077.81%60.06%-49.35%10.06%-41.72%337.99%
Book Value per Share12.106.372.5311.3612.574.832.940.932.17
Total Shareholders' Equity11.12M9.18M5.72M67.41M107.89M54.64M60.14M35.05M153.51M
Common Stock12K15K69K142K88K142K26K38K84K
Retained Earnings-130.4M-153.53M-87.94M-91.33M-263.57M-105.93M-399.58M-467.37M-462.55M
Treasury Stock000000000
Accumulated OCI-268K302K00-267K0106K-120K-95K
Minority Interest000000000

LPTX Cash Flow Statement

Leap Therapeutics, Inc. (LPTX) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-22.14M-26.03M-26.9M-25.96M-35.16M-49.04M-43.75M-60.3M-43.9M
Operating CF Margin %---277.91%-258.2%-2343.8%----
Operating CF Growth %12.63%-17.6%-3.34%3.51%-35.44%-39.5%10.79%-37.82%27.19%
Net Income-29.73M-23.14M-32.9M-27.51M-40.59M-54.6M-81.41M-67.56M4.82M
Depreciation & Amortization48K49K47K34K29K16K15K5K0
Stock-Based Compensation5.6M3.47M3.89M2.62M3.48M5.18M5.13M5.5M4.9M
Deferred Taxes-158K20K00379K0005.12M
Other Non-Cash Items-194K-7.3M729K-104K527K1.01M30.01M457K-58.74M
Working Capital Changes2.29M871K1.33M-990K1.01M-651K2.51M1.29M0
Change in Receivables1.46M780K643K117K-1.16M-1.01M1.3M00
Change in Inventory00001.16M0000
Change in Payables1.09M368K003.9M0712K902K-10.42M
Cash from Investing-64K0-85K25K0048.97M0-97M
Capital Expenditures-64K0-100K000000
CapEx % of Revenue--1.03%------
Acquisitions00000050.36M00
Investments---------
Other Investing-64K015K25K00-1.39M0-97M
Cash from Financing47.76M15.91M14.82M74M98.03M-210K-30K37.18M107.65M
Debt Issued (Net)750K00000000
Equity Issued (Net)1000K1000K1000K1000K1000K0-29K1000K0
Dividends Paid000000000
Share Repurchases000000-1K00
Other Financing-2.15M872K-437K-1.51M813K-210K-1K-2.81M107.65M
Net Change in Cash
24.94M▲ 0%
-9.45M▼ 137.9%
-12.39M▼ 31.1%
48.18M▲ 488.8%
62.84M▲ 30.4%
-49.42M▼ 178.6%
5.14M▲ 110.4%
-23.39M▼ 554.9%
-33.21M▼ 42.0%
Free Cash Flow
-22.2M▲ 0%
-26.03M▼ 17.3%
-27M▼ 3.7%
-25.96M▲ 3.9%
-35.16M▼ 35.4%
-49.04M▼ 39.5%
-43.75M▲ 10.8%
-60.3M▼ 37.8%
-43.9M▲ 27.2%
FCF Margin %---278.95%-258.2%-2343.8%----
FCF Growth %12.87%-17.26%-3.72%3.87%-35.44%-39.5%10.79%-37.82%27.19%
FCF per Share-24.16-18.06-11.96-4.38-4.10-4.33-2.14-1.61-0.62
FCF Conversion (FCF/Net Income)0.74x1.13x7.81x7.66x0.87x0.90x0.54x0.89x-2.86x
Interest Paid000000000
Taxes Paid000000000

LPTX Key Ratios

Leap Therapeutics, Inc. (LPTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)--267.4%-228.05%-46.26%-9.26%-46.31%-67.18%-141.86%-141.94%16.26%
Return on Invested Capital (ROIC)-----59.48%--308.35%-545.53%--48.29%
Gross Margin---52.93%50.94%100%----
Net Margin----35.6%-33.69%-2705.8%----
Debt / Equity---0.18x0.01x0.00x0.01x0.00x0.01x0.00x
Interest Coverage-22.32x-267.37x-1618.47x-151.13x-88.36x-1010.39x-1051.17x---
FCF Conversion0.99x0.74x1.13x7.81x7.66x0.87x0.90x0.54x0.89x-2.86x
Revenue Growth----3.85%-85.08%-100%---

LPTX Frequently Asked Questions

Leap Therapeutics, Inc. (LPTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Leap Therapeutics, Inc. (LPTX) reported $0.2M in revenue for fiscal year 2025.

Leap Therapeutics, Inc. (LPTX) grew revenue by 0.0% over the past year. Growth has been modest.

Yes, Leap Therapeutics, Inc. (LPTX) is profitable, generating $15.3M in net income for fiscal year 2025 (7335.9% net margin).

Dividend & Returns

Leap Therapeutics, Inc. (LPTX) has a return on equity (ROE) of 16.3%. This is reasonable for most industries.

Leap Therapeutics, Inc. (LPTX) had negative free cash flow of $90.7M in fiscal year 2025, likely due to heavy capital investments.

Explore More LPTX

Leap Therapeutics, Inc. (LPTX) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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