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XCURExicure, Inc.
$2.40$15M
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XCUR logoExicure, Inc.(XCUR)Earnings, Financials & Key Ratios

XCUR•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryRNA and Genome Editing Developers
AboutExicure, Inc., a biotechnology company, develops therapies for neurological disorders and hair loss based on its proprietary spherical nucleic acid (SNA) technology. Its lead program candidate includes SCN9A that is in preclinical studies for neuropathic and chronic pain. The company has a collaboration, option, and license agreement with AbbVie Inc. to develop SNA-based treatments for hair loss disorders; and collaboration agreement with Ipsen S.A. to research, develop, and commercialize novel spherical nucleic acids for Huntington's disease and Angelman syndrome. Exicure, Inc. was founded in 2011 and is headquartered in Chicago, Illinois.Show more
  • Revenue$0-100.0%
  • EBITDA-$10M+15.3%
  • Net Income-$5M+49.0%
  • EPS (Diluted)-0.79+50.3%
  • ROE-92.47%+53.3%

XCUR Key Insights

Exicure, Inc. (XCUR) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y profit CAGR of 27.5%
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Healthy 5Y average net margin of 3774.2%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Weak momentum: RS Rating 6 (bottom 6%)
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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XCUR Price & Volume

Exicure, Inc. (XCUR) stock price & volume — 10-year historical chart

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XCUR Growth Metrics

Exicure, Inc. (XCUR) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-66.91%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-67.5%

Return on Capital

10 Years-76.19%
5 Years-83.71%
3 Years-101.7%
Last Year-91.4%

XCUR Recent Earnings

Exicure, Inc. (XCUR) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 3/12 qtrs (100%)●Beat Revenue 1/12 qtrs (100%)
Q2 2026Latest
May 29, 2026
Metric
Actual
Est
EPS
$0.29+98.4%
$18.60
Rev
—
$2M
Q2 2026
Mar 25, 2026
Metric
Actual
Est
EPS
$0.46+51.6%
$0.95
Rev
—
$4M
Q4 2025
Nov 7, 2025
Metric
Actual
Est
EPS
$0.39
—
Rev
—
—
Q3 2025
Aug 8, 2025
Metric
Actual
Est
EPS
$0.41
—
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 29, 2026
$0.29vs $18.60+98.4%
—vs $2M
Q2 2026Mar 25, 2026
$0.46vs $0.95+51.6%
—vs $4M
Q4 2025Nov 7, 2025
$0.39
—
Q3 2025Aug 8, 2025
$0.41
—
Based on last 12 quarters of dataView full earnings history →

XCUR Peer Comparison

Exicure, Inc. (XCUR) competitors in RNA and Genome Editing Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
SRPT logoSRPTSarepta Therapeutics, Inc.Direct Competitor1.85B17.53-2.4615.58%2.98%4.89%0.91
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor11.52B81.82-6706.56232.58%-48.38%-55.09%0.73
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.76B15.67-4.1116.92%-5.97%-57.27%0.14
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.51B34.14-42.15120.01%-49.17%-5.89%0.24
EDIT logoEDITEditas Medicine, Inc.Direct Competitor263.37M2.69-1.4925.39%-281.59%-6.77%2.81
CRSP logoCRSPCRISPR Therapeutics AGDirect Competitor5.22B54.09-8.36-89.97%-138.57%-30.88%0.21
IONS logoIONSIonis Pharmaceuticals, Inc.Product Competitor12.25B74.12-31.1433.87%-30.87%-58.57%5.35
REGN logoREGNRegeneron Pharmaceuticals, Inc.Product Competitor63.37B609.9414.700.99%29.65%14.32%0.09

Compare XCUR vs Peers

Exicure, Inc. (XCUR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for XCUR.

Scale Benchmark

vs TMO

Larger-name benchmark to compare XCUR against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, ARWR, NTLA, BEAM

XCUR Income Statement

Exicure, Inc. (XCUR) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
9.72M118K1.3M16.61M-483K28.83M0500K00
Revenue Growth %
838.13%-98.79%998.31%1181.87%-102.91%6068.12%-100%--100%-
Cost of Goods Sold
13.08M14.12M032.09M01.86M1.42M0460K263K
COGS % of Revenue
134.58%11965.25%-193.19%-6.44%----
Gross Profit
-3.36M▲ 0%
-14M▼ 316.6%
1.3M▲ 109.3%
-15.48M▼ 1294.5%
-483K▲ 96.9%
26.97M▲ 5683.9%
-1.42M▼ 105.3%
500K▲ 135.1%
-460K▼ 192.0%
-263K▲ 0%
Gross Margin %
-34.58%-11865.25%100%-93.19%100%93.56%-100%--
Gross Profit Growth %
73.37%-316.57%109.26%-1294.52%96.88%5683.85%-105.28%135.14%-192%-
Operating Expenses
20.13M21.94M27.91M9.96M62.07M28.8M13.57M12.73M9.66M8.5M
OpEx % of Revenue
207.08%18590.68%2153.78%59.92%-12850.1%99.91%-2546.4%--
Selling, General & Admin
7.05M7.82M8.57M9.96M13.09M10.89M12.65M5.45M6.83M5.8M
SG&A % of Revenue
72.5%6625.42%661.5%59.92%-2709.52%37.78%-1089.8%--
Research & Development
13.08M14.12M19.34M32.09M48.98M19.77M1.42M03.29M2.79M
R&D % of Revenue
134.58%11965.25%1492.28%193.19%-10140.58%68.57%----
Other Operating Expenses
191K-249K0-32.09M0-1.86M-503K7.28M-460K-93K
Operating Income
-10.41M▲ 0%
-21.82M▼ 109.7%
-26.62M▼ 22.0%
-25.44M▲ 4.4%
-62.55M▼ 145.9%
-1.83M▲ 97.1%
-15M▼ 719.0%
-12.23M▲ 18.4%
-10.12M▲ 17.3%
-8.76M▲ 0%
Operating Margin %
-107.08%-18490.68%-2053.78%-153.11%12950.1%-6.35%--2446.4%--
Operating Income Growth %
35.61%-109.66%-21.99%4.44%-145.91%97.07%-719.01%18.43%17.29%-
EBITDA
-10.18M-21.46M-25.89M-23.99M-60.77M25K-13.62M-11.41M-9.66M-8.3M
EBITDA Margin %
-104.69%-18187.29%-1997.92%-144.4%12581.78%0.09%--2281.6%--
EBITDA Growth %
36.33%-110.92%-20.65%7.35%-153.32%100.04%-54584%16.25%15.35%-7.53%
D&A (Non-Cash Add-back)
232K358K724K1.45M1.78M1.86M1.38M824K460K462K
EBIT
-10.22M-21.74M-25.52M-24.09M-62.41M-1.78M-16.91M-9.68M-10.12M-8.74M
Net Interest Income
-795K-668K-608K399K-1.55M-580K32K-10K28K23K
Interest Income
04K178K972K141K15K32K8K29K24K
Interest Expense
795K672K786K573K1.69M595K018K1K1K
Other Income/Expense
-604K-594K314K768K-1.55M-542K-1.92M2.54M4.54M-1.66M
Pretax Income
-11.01M▲ 0%
-22.41M▼ 103.6%
-26.3M▼ 17.4%
-24.67M▲ 6.2%
-64.1M▼ 159.9%
-2.37M▲ 96.3%
-16.91M▼ 612.8%
-9.69M▲ 42.7%
-5.58M▲ 42.4%
-10.42M▲ 0%
Pretax Margin %
-113.29%-18994.07%-2029.55%-148.49%13271.64%-8.23%--1938.6%--
Income Tax
00000209K08K-634K-634K
Effective Tax Rate %
0%0%0%0%0%-8.81%0%-0.08%11.36%6.09%
Net Income
-11.01M▲ 0%
-22.41M▼ 103.6%
-26.3M▼ 17.4%
-24.67M▲ 6.2%
-64.1M▼ 159.9%
-2.58M▲ 96.0%
-16.91M▼ 555.1%
-9.7M▲ 42.6%
-4.95M▲ 49.0%
-9.78M▲ 0%
Net Margin %
-113.29%-18994.07%-2029.55%-148.49%13271.64%-8.96%--1940.2%--
Net Income Growth %
35%-103.55%-17.36%6.22%-159.86%95.97%-555.07%42.65%49.02%-66.91%
Net Income (Continuing)
-11.01M-22.41M-26.3M-24.67M-64.1M-2.58M-16.91M-9.7M-4.95M-9.78M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-8.37▲ 0%
-16.32▼ 95.0%
-13.68▲ 16.2%
-8.49▲ 37.9%
-21.70▼ 155.6%
-0.56▲ 97.4%
-2.11▼ 276.8%
-1.59▲ 24.6%
-0.79▲ 50.3%
-1.54▲ 0%
EPS Growth %
35.02%-94.98%16.18%37.94%-155.59%97.42%-276.79%24.64%50.31%-67.5%
EPS (Basic)
-8.37-16.32-13.68-8.49-21.70-0.56-2.11-1.59-0.79-
Diluted Shares Outstanding
1.32M1.37M1.92M2.91M2.95M4.62M8.01M6.1M6.3M6.37M
Basic Shares Outstanding
1.32M1.37M1.92M2.91M2.95M4.62M8.01M6.1M6.3M6.37M
Dividend Payout Ratio
----------

XCUR Balance Sheet

Exicure, Inc. (XCUR) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
27.64M27.66M112.78M86.32M43.67M10.05M2.02M13.67M4.62M3.53M
Cash & Short-Term Investments
25.76M26.27M110.79M82.08M39.14M8.58M816K12.51M3.75M2.6M
Cash Only
25.76M26.27M48.46M33.26M34.64M8.58M816K12.51M3.75M2.6M
Short-Term Investments
0062.33M48.82M4.5M00000
Accounts Receivable
30K3K35K11K00250K521K58K60K
Days Sales Outstanding
1.139.289.860.24---380.33--
Inventory
0646K00000000
Days Inventory Outstanding
-16.7--------
Other Current Assets
0746K01.2M1.28M853K24K69K820K868K
Total Non-Current Assets
1.35M1.09M2.49M14.12M21.2M13.28M9.56M1.38M9.42M9.22M
Property, Plant & Equipment
1.32M1.06M2.46M12.73M11.88M9.79M6.57M26K306K219K
Fixed Asset Turnover
7.38x0.11x0.53x1.31x-0.04x2.95x-19.23x-0.00x
Goodwill
000000004.4M4.4M
Intangible Assets
000000003.78M3.78M
Long-Term Investments
000001.2M1.2M000
Other Non-Current Assets
32K32K32K1.39M9.32M2.29M1.78M1.36M928K821K
Total Assets
28.99M▲ 0%
28.76M▼ 0.8%
115.26M▲ 300.8%
100.44M▼ 12.9%
64.87M▼ 35.4%
23.33M▼ 64.0%
11.58M▼ 50.4%
15.06M▲ 30.0%
14.04M▼ 6.7%
12.76M▲ 0%
Asset Turnover
0.34x0.00x0.01x0.17x-0.01x1.24x-0.03x-0.00x
Asset Growth %
40.88%-0.8%300.83%-12.86%-35.42%-64.04%-50.36%30.02%-6.74%73.86%
Total Current Liabilities
3.36M2.04M31.09M13.73M34.07M1.64M2.51M3.07M3.89M4.46M
Accounts Payable
1.05M500K1.81M1.87M3.41M361K1.63M1.03M1.69M2.44M
Days Payables Outstanding
29.2712.93-21.22-70.99418.35-1.34K2.53K
Short-Term Debt
004.96M06.87M539K00176K22K
Deferred Revenue (Current)
1.03M021.87M017.32M00000
Other Current Liabilities
001.22M8.34M0707K002.02M1.99M
Current Ratio
8.24x13.54x3.63x6.29x1.28x6.13x0.81x4.45x1.19x0.79x
Quick Ratio
8.24x13.22x3.63x6.29x1.28x6.13x0.81x4.45x1.19x0.79x
Cash Conversion Cycle
-13.05--------
Total Non-Current Liabilities
5.66M5.76M3.43M25.2M19.57M6.77M6.04M5.21M6.23M6.2M
Long-Term Debt
4.86M4.92M016.59M000000
Capital Lease Obligations
0059K7.96M7.4M6.77M6.04M5.21M026K
Deferred Tax Liabilities
00000000423K846K
Other Non-Current Liabilities
801K836K414K656K656K0005.8M5.77M
Total Liabilities
9.01M7.8M34.52M38.94M53.64M8.41M8.55M8.28M10.12M10.66M
Total Debt
4.86M4.92M5.32M24.77M14.74M7.31M6.67M5.93M176K22K
Net Debt
-20.91M-21.34M-43.14M-8.49M-19.91M-1.27M5.85M-6.57M-3.57M-2.58M
Debt / Equity
0.24x0.24x0.07x0.40x1.31x0.49x2.20x0.88x0.04x0.01x
Debt / EBITDA
-----292.24x----0.00x
Net Debt / EBITDA
------50.84x---0.31x
Interest Coverage
-12.85x-32.35x-32.46x-42.05x-36.91x-2.99x--537.50x-10117.00x-8745.00x
Total Equity
19.98M▲ 0%
20.95M▲ 4.9%
80.75M▲ 285.4%
61.51M▼ 23.8%
11.23M▼ 81.7%
14.92M▲ 32.9%
3.03M▼ 79.7%
6.77M▲ 123.4%
3.93M▼ 42.0%
2.1M▲ 0%
Equity Growth %
715.97%4.89%285.39%-23.83%-81.74%32.85%-79.69%123.42%-42.03%674.23%
Book Value per Share
15.1915.2642.0021.163.803.230.381.110.620.33
Total Shareholders' Equity
19.98M20.95M80.75M61.51M11.23M14.92M3.03M6.77M3.93M2.1M
Common Stock
4K4K9K9K11K001K1K1K
Retained Earnings
-33.62M-54.99M-81.3M-105.97M-170.07M-172.65M-189.56M-199.26M-204.21M-206.04M
Treasury Stock
0000000000
Accumulated OCI
00-27K83K-2K000-2K-2K
Minority Interest
0000000000

XCUR Cash Flow Statement

Exicure, Inc. (XCUR) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-19.79M-19.49M1.32M-39.27M-34.82M-35.66M-10.36M-2.91M-8.55M-8.1M
Operating CF Margin %
-203.61%-16514.41%101.62%-236.38%7208.9%-123.7%--582%--
Operating CF Growth %
-291.86%1.53%106.76%-3081.78%11.33%-2.41%70.95%71.9%-193.99%-788.66%
Net Income
-11.01M-22.41M-26.3M-24.67M-64.1M-2.58M-16.91M-9.7M-4.95M-9.78M
Depreciation & Amortization
232K358K724K1.45M1.78M1.86M1.38M824K460K586K
Stock-Based Compensation
1.46M1.81M1.84M2.18M2.94M1.37M1.35M22K2K3K
Deferred Taxes
-214K274K-386K00000-634K-634K
Other Non-Cash Items
-25K496K228K99K460K514K2.92M5.31M-4.58M6.81M
Working Capital Changes
-10.45M-11K25.21M-18.33M24.11M-36.81M914K631K1.14M-145K
Change in Receivables
-13K10K-32K24K11K00-506K1.34M3K
Change in Inventory
-2.35M775K-372K0000000
Change in Payables
195K-557K789K364K1.58M-3.05M1.27M-193K177K1.36M
Cash from Investing
-926K-94K-63.43M10.14M43.09M4.7M-1.08M0-1.81M283K
Capital Expenditures
-926K-94K-1.08M-3.17M-968K-10K00-1K-215K
CapEx % of Revenue
9.53%79.66%83.49%19.09%-200.41%0.03%----
Acquisitions
00000000-1.81M42K
Investments
----------
Other Investing
00000205K922K00456K
Cash from Financing
26.86M20.09M84.31M15.13M1.12M-3.1M3.67M13.4M1.6M0
Debt Issued (Net)
-1M0012.5M-10M-7.5M01M00
Equity Issued (Net)
31.51M22M90.75M2.97M11.48M5.04M5.44M12.4M1.6M0
Dividends Paid
000000000-79K
Share Repurchases
0000000000
Other Financing
-3.66M-1.92M-6.44M-344K-362K-645K-1.77M0079K
Net Change in Cash
6.14M▲ 0%
504K▼ 91.8%
22.19M▲ 4303.2%
-14M▼ 163.1%
9.38M▲ 167.0%
-34.07M▼ 463.1%
-7.76M▲ 77.2%
10.49M▲ 235.2%
-8.76M▼ 183.5%
-7.82M▲ 0%
Free Cash Flow
-20.71M▲ 0%
-19.58M▲ 5.5%
235K▲ 101.2%
-42.44M▼ 18160.0%
-35.79M▲ 15.7%
-35.67M▲ 0.3%
-10.36M▲ 71.0%
-2.91M▲ 71.9%
-8.56M▼ 194.0%
-8.1M▲ 0%
FCF Margin %
-213.14%-16594.07%18.13%-255.47%7409.32%-123.74%--582%--
FCF Growth %
-280.51%5.47%101.2%-18160%15.68%0.33%70.96%71.9%-194.02%-99.61%
FCF per Share
-15.75-14.260.12-14.60-12.12-7.72-1.29-0.48-1.36-1.27
FCF Conversion (FCF/Net Income)
1.80x0.87x-0.05x1.59x0.54x13.81x0.61x0.30x1.73x0.83x
Interest Paid
0000000000
Taxes Paid
0000000000

XCUR Key Ratios

Exicure, Inc. (XCUR) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-98.21%-109.53%-51.73%-34.68%-176.25%-19.74%-188.43%-197.92%-92.47%-179.41%
Return on Invested Capital (ROIC)
---107.29%-42.1%-211.6%-55.21%-99.84%-202.09%-2734.32%-624.45%
Gross Margin
-34.58%-11865.25%100%-93.19%100%93.56%-100%--
Net Margin
-113.29%-18994.07%-2029.55%-148.49%13271.64%-8.96%--1940.2%--
Debt / Equity
0.24x0.24x0.07x0.40x1.31x0.49x2.20x0.88x0.04x0.01x
Interest Coverage
-12.85x-32.35x-32.46x-42.05x-36.91x-2.99x--537.50x-10117.00x-8745.00x
FCF Conversion
1.80x0.87x-0.05x1.59x0.54x13.81x0.61x0.30x1.73x0.83x
Revenue Growth
838.13%-98.79%998.31%1181.87%-102.91%6068.12%-100%--100%-
Related:XCUR Dividend History·XCUR Revenue History·XCUR Price History·XCUR P/E History·XCUR Financial Ratios·XCUR Institutional Holders

XCUR SEC Filings & Documents

Exicure, Inc. (XCUR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jun 1, 2026·SEC

Material company update

Apr 10, 2026·SEC

Material company update

Apr 2, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 25, 2026·SEC

FY 2025

Mar 18, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 29, 2026·SEC

FY 2025

Nov 7, 2025·SEC

FY 2025

Aug 8, 2025·SEC

XCUR Frequently Asked Questions

Exicure, Inc. (XCUR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Exicure, Inc. (XCUR) saw revenue decline by 100.0% over the past year.

Exicure, Inc. (XCUR) reported a net loss of $9.8M for fiscal year 2025.

Dividend & Returns

Exicure, Inc. (XCUR) has a return on equity (ROE) of -92.5%. Negative ROE indicates the company is unprofitable.

Exicure, Inc. (XCUR) had negative free cash flow of $8.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in XCUR back in 2015?

Total return calculator · dividends reinvested · 11+ years of data

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How much would $100/month in XCUR be worth today?

Dollar cost averaging calculator · DCA vs lump sum

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