Latest Ratios: P/E Ratio -1.9x · EV/EBITDA N/A · ROE -53.4%. (2017–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $576M | $302M | $415M | $504M | $900M | $2.0B | $3.0B | $2.6B | $2.4B | — |
| Enterprise Value | $608M | $334M | $430M | $516M | $940M | $1.9B | $2.9B | $2.5B | $1.7B | — |
| P/E Ratio → | -1.92 | — | — | — | — | — | — | — | — | — |
| P/S Ratio | — | — | 18861.34 | 5302.65 | 5771.76 | 17.76 | — | — | — | — |
| P/B Ratio | 1.26 | 1.03 | 0.98 | 0.98 | 1.35 | 2.19 | 2.81 | 4.17 | 3.43 | — |
| P/FCF | — | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | — | 19567.62 | 5428.61 | 6023.17 | 16.88 | — | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | 100.0% | 100.0% | -9063.5% | 100.0% | — | — | — | — |
| Operating Margin | — | — | -1241813.6% | -344986.3% | -215087.2% | -157.9% | — | — | — | — |
| Net Profit Margin | — | — | -1170863.6% | -344489.5% | -218214.1% | -159.6% | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -53.4% | -53.4% | -55.1% | -55.5% | -42.8% | -18.2% | -29.3% | -27.7% | -60.2% | — |
| ROA | -39.6% | -39.6% | -43.2% | -44.7% | -36.4% | -16.0% | -25.7% | -24.8% | -27.3% | — |
| ROIC | -40.7% | -40.7% | -42.6% | -40.0% | -32.9% | -15.2% | -26.6% | -57.9% | -1778.1% | — |
| ROCE | -46.2% | -46.2% | -48.8% | -47.7% | -37.9% | -16.9% | -28.4% | -28.3% | -25.4% | — |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.28 | 0.28 | 0.21 | 0.19 | 0.15 | 0.08 | 0.05 | 0.08 | 0.05 | — |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | 0.11 | 0.04 | 0.02 | 0.06 | -0.11 | -0.12 | -0.19 | -0.98 | — |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | 0.00 |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — |
| Interest Coverage | -176.57 | -176.57 | -1419.70 | — | — | — | — | — | -62.02 | — |
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.93 | 7.93 | 8.54 | 12.38 | 9.84 | 9.84 | 8.96 | 16.46 | 15.89 | — |
| Quick Ratio | 7.93 | 7.93 | 8.54 | 12.38 | 9.84 | 9.84 | 8.96 | 16.46 | 24.78 | — |
| Cash Ratio | 7.70 | 7.70 | 8.23 | 12.10 | 9.63 | 9.55 | 8.78 | 16.04 | 24.49 | — |
| Asset Turnover | — | — | 0.00 | 0.00 | 0.00 | 0.11 | — | — | — | — |
| Inventory Turnover | — | — | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | — | 31522.73 | 6531.58 | — | — | — | — | — | — |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — |
| Shares Outstanding | — | $221M | $195M | $157M | $143M | $136M | $120M | $101M | $90M | $44M |
Includes 30+ ratios · 9 years · Updated daily
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Quick answers to the most common questions about buying ALLO stock.
Allogene Therapeutics, Inc.'s current P/E ratio is -1.9x. This places it at the 50th percentile of its historical range.
Allogene Therapeutics, Inc.'s return on equity (ROE) is -53.4%. The historical average is -42.8%.
Based on historical data, Allogene Therapeutics, Inc. is trading at a P/E of -1.9x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Key Metrics
Top Statement Risk
Cash runway insufficient
Metrics are mathematically derived from official filings.
Liquidity Buffer Shrinking Rapidly
Current ratio remains high at 10.72, but cash fell from $170.7M to $38.6M over eight quarters, per balance sheet data, implying less than one quarter of runway at current burn.
The current ratio of 10.72 in 2026Q2 appears robust, yet it is inflated by the absence of near-term liabilities rather than by ample cash. Cash and equivalents dropped 77% from $170.7M in 2024Q2 to $38.6M in 2026Q2, while quarterly net losses averaged around $45M, suggesting the liquidity cushion is largely illusory. Investors should monitor whether the company can secure additional financing or partnerships before the cash balance is fully depleted.
Modest Debt but Rising Risk
Debt-to-equity improved to 0.16 from 0.21, but interest coverage is deeply negative at -136.8, per reported figures, indicating that debt service is not a current concern but refinancing risk looms.
Total debt declined from $95.8M to $70.4M, and the D/E ratio fell to 0.16, suggesting a conservative capital structure. However, with negative EBITDA and interest coverage of -136.8, the company is not generating any earnings to service debt, making it reliant on cash reserves or new financing. The low absolute debt level provides some cushion, but the lack of revenue and persistent losses heighten the risk of covenant breaches or forced dilution.
Working Capital Distortions
Asset turnover is near zero and DSO is unavailable, but DPO swings from 11 to 155 days, per quarterly data, indicating erratic supplier payment patterns that obscure true cash conversion.
The efficiency metrics are largely uninformative for a pre-revenue biotech, as asset turnover is effectively zero and DSO is not reported. The wide fluctuation in days payable outstanding, from 11 days in 2025Q2 to 155 days in 2024Q4, suggests that working capital management is not a strategic focus but rather a byproduct of irregular spending and payment timing. This volatility complicates any assessment of operational efficiency, and investors should instead focus on the cash burn rate relative to clinical milestones.
Persistent Negative Returns
ROIC has hovered around -10% for eight quarters, with ROE at -11.9% in 2026Q2, per reported figures, indicating the company is consistently destroying capital as it funds R&D.
Return on invested capital has remained deeply negative, ranging from -8.8% to -11.5% over the past two years, reflecting the absence of revenue and heavy R&D spending. ROE similarly stayed around -13% to -15%, with a slight improvement to -11.9% in 2026Q2, but this is due to cost cuts rather than value creation. The negative returns are expected for a clinical-stage company, but the lack of improvement suggests that the capital deployed has not yet generated any tangible progress toward commercialization.
Relative Burn Efficiency
Allogene's ROE of -11.9% is less negative than Fate's -58.9% and Editas' -196.6%, per peer data, but its cash position is far weaker, suggesting a shorter runway than peers.
Compared to allogeneic peers, Allogene's ROE and ROIC are less negative than Fate Therapeutics and Editas Medicine, indicating a relatively more controlled burn rate. However, with only $51.7M in cash versus CRISPR's $5.2B market cap and Fate's $317M, Allogene's financial flexibility is significantly constrained. The peer comparison suggests that while Allogene is not the worst capital consumer, its liquidity position is the most precarious, making it more vulnerable to adverse clinical outcomes.
Misapplied P/B Multiple
The price-to-book ratio of 1.56 appears low, but for a pre-revenue biotech, book value is largely cash and PP&E, obscuring the true value of the pipeline, per reported figures.
Investors often use P/B to gauge downside support, but for Allogene, book value is dominated by cash, manufacturing assets, and accumulated deficits, not by revenue-generating assets. The P/B of 1.56 may seem attractive, but it fails to capture the value of the clinical pipeline, which is the primary driver of the stock. A more appropriate metric would be EV/Invested Capital or a risk-adjusted NPV of the pipeline, as the book value provides little insight into the company's future earning potential.