Revenue growth rebounded to 5.4% YoY in 2026Q2 with gross margin recovering to 50.8%, but operating margin remains below the 30.3% peak in 2024Q2, reflecting R&D and SG&A investment surges.
Amphastar Pharmaceuticals, Inc. (AMPH) annual income statement — 14-year revenue, gross profit & net income history
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 |
|---|
| Sales/Revenue | 730.02M | 719.89M | 731.97M | 644.39M | 498.99M | 437.77M | 349.85M | 322.36M | 294.67M | 240.18M | 255.16M | 251.52M | 210.46M | 229.68M | 204.32M |
| Revenue Growth % | 1.35% | -1.65% | 13.59% | 29.14% | 13.98% | 25.13% | 8.53% | 9.4% | 22.69% | -5.87% | 1.45% | 19.51% | -8.37% | 12.41% | - |
| Cost of Goods Sold | 381.91M | 363.83M | 358.11M | 293.27M | 250.13M | 238.03M | 206.51M | 190.43M | 187.68M | 149.38M | 150.98M | 174.17M | 159.21M | 142.72M | 114.02M |
| COGS % of Revenue | - | 50.54% | 48.92% | 45.51% | 50.13% | 54.37% | 59.03% | 59.08% | 63.69% | 62.2% | 59.17% | 69.25% | 75.65% | 62.14% | 55.8% |
| Gross Profit | 348.11M | 356.06M | 373.86M | 351.12M | 248.86M | 199.74M | 143.34M | 131.92M | 106.98M | 90.8M | 104.19M | 77.35M | 51.26M | 86.96M | 90.3M |
| Gross Margin % | 47.68% | 49.46% | 51.08% | 54.49% | 49.87% | 45.63% | 40.97% | 40.92% | 36.31% | 37.8% | 40.83% | 30.75% | 24.35% | 37.86% | 44.2% |
| Gross Profit Growth % | - | -4.76% | 6.47% | 41.09% | 24.59% | 39.35% | 8.65% | 23.31% | 17.83% | -12.86% | 34.7% | 50.9% | -41.06% | -3.71% | - |
| Operating Expenses | 233.82M | 215.65M | 168.44M | 154.13M | 141.36M | 129.85M | 132.39M | 131.96M | 115.61M | 94.33M | 88.5M | 84.04M | 68.8M | 69.34M | 62.81M |
| OpEx % of Revenue | - | 29.96% | 23.01% | 23.92% | 28.33% | 29.66% | 37.84% | 40.94% | 39.23% | 39.28% | 34.68% | 33.41% | 32.69% | 30.19% | 30.74% |
| Selling, General & Admin | 139.25M | 129.81M | 94.52M | 80.39M | 66.59M | 68.92M | 65.16M | 63.11M | 58.04M | 50.92M | 47.3M | 46.97M | 40.37M | 36.32M | 31.65M |
| SG&A % of Revenue | - | 18.03% | 12.91% | 12.48% | 13.35% | 15.74% | 18.62% | 19.58% | 19.7% | 21.2% | 18.54% | 18.68% | 19.18% | 15.81% | 15.49% |
| Research & Development | 94.57M | 85.84M | 73.91M | 73.74M | 74.77M | 60.93M | 67.23M | 68.85M | 57.56M | 43.41M | 41.2M | 37.06M | 28.43M | 33.02M | 31.16M |
| R&D % of Revenue | - | 11.92% | 10.1% | 11.44% | 14.98% | 13.92% | 19.22% | 21.36% | 19.54% | 18.08% | 16.15% | 14.74% | 13.51% | 14.38% | 15.25% |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -746K | 0 | -165K | 508K | 0 |
| Operating Income | 114.28M | 140.4M | 205.42M | 196.99M | 107.5M | 69.89M | 10.95M | -39K | -8.62M | -895K | 15.69M | -6.9M | -17.98M | 17.49M | 25.4M |
| Operating Margin % | 15.66% | 19.5% | 28.06% | 30.57% | 21.54% | 15.96% | 3.13% | -0.01% | -2.93% | -0.37% | 6.15% | -2.74% | -8.54% | 7.61% | 12.43% |
| Operating Income Growth % | - | -31.65% | 4.28% | 83.25% | 53.82% | 538% | 28187.18% | 99.55% | -863.46% | -105.7% | 327.49% | 61.64% | -202.82% | -31.13% | - |
| EBITDA | 166.37M | 203.6M | 262.62M | 238.76M | 135.77M | 96.42M | 36.13M | 21.08M | 7.89M | 14.91M | 30.26M | 6.35M | -3.54M | 30.57M | 36.89M |
| EBITDA Margin % | 22.79% | 28.28% | 35.88% | 37.05% | 27.21% | 22.03% | 10.33% | 6.54% | 2.68% | 6.21% | 11.86% | 2.53% | -1.68% | 13.31% | 18.06% |
| EBITDA Growth % | -31.31% | -22.47% | 9.99% | 75.86% | 40.81% | 166.84% | 71.4% | 167.1% | -47.08% | -50.7% | 376.17% | 279.75% | -111.56% | -17.15% | - |
| D&A (Non-Cash Add-back) | 46.61M | 63.2M | 57.2M | 41.78M | 28.27M | 26.53M | 25.18M | 21.12M | 16.52M | 15.81M | 14.56M | 13.25M | 14.45M | 13.08M | 11.5M |
| EBIT | 128.15M | 149.1M | 220.11M | 198.52M | 117.89M | 85.02M | 5.01M | 60.35M | -9.68M | 2.08M | 15.97M | -9.38M | -17.54M | 17.62M | 26.66M |
| Net Interest Income | -16.77M | -16.8M | -19.73M | -21.7M | -525K | -284K | 268K | 878K | 213K | -401K | -754K | -672K | -366K | -771K | -542K |
| Interest Income | 9.36M | 8.68M | 10.61M | 5.46M | 1.32M | 601K | 642K | 997K | 456K | 425K | 270K | 315K | 243K | 187K | 242K |
| Interest Expense | 26.13M | 25.48M | 30.34M | 27.16M | 1.85M | 885K | 374K | 119K | 243K | 826K | 1.02M | 987K | 609K | 958K | 784K |
| Other Income/Expense | -12.26M | -16.78M | -16.23M | -27.61M | 7.37M | 14.04M | -6.32M | 60.27M | -1.3M | 2.52M | -746K | -3.47M | -165K | -263K | -1.61M |
| Pretax Income | 102.02M | 123.62M | 189.19M | 169.38M | 114.86M | 83.93M | 4.64M | 60.23M | -9.93M | 1.62M | 14.95M | -10.36M | -18.15M | 17.23M | 25.88M |
| Pretax Margin % | 13.98% | 17.17% | 25.85% | 26.28% | 23.02% | 19.17% | 1.33% | 18.68% | -3.37% | 0.68% | 5.86% | -4.12% | -8.62% | 7.5% | 12.67% |
| Income Tax | 23.48M | 25.53M | 29.67M | 31.83M | 23.48M | 20.63M | 3.54M | 13.72M | -3.27M | -2.88M | 4.41M | -7.58M | -7.45M | 5.37M | 7.78M |
| Effective Tax Rate % | 23.01% | 20.65% | 15.68% | 18.79% | 20.44% | 24.58% | 76.34% | 22.79% | 32.9% | -177.76% | 29.53% | 73.11% | 41.05% | 31.14% | 30.08% |
| Net Income | 78.55M | 98.09M | 159.52M | 137.54M | 91.39M | 62.12M | 1.4M | 48.94M | -5.74M | 4.51M | 10.53M | -2.79M | -10.7M | 11.86M | 18.09M |
| Net Margin % | 10.76% | 13.63% | 21.79% | 21.34% | 18.31% | 14.19% | 0.4% | 15.18% | -1.95% | 1.88% | 4.13% | -1.11% | -5.08% | 5.16% | 8.86% |
| Net Income Growth % | -41.69% | -38.51% | 15.98% | 50.51% | 47.12% | 4327.37% | -97.13% | 952.89% | -227.28% | -57.2% | 477.9% | 73.95% | -190.2% | -34.44% | - |
| Net Income (Continuing) | 78.55M | 98.09M | 159.52M | 137.54M | 91.39M | 63.3M | 1.1M | 46.51M | -6.66M | 3.65M | 9.82M | -2.79M | -10.7M | 11.86M | 18.09M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 46.42M | 46.16M | 31.92M | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | 1.78 | 2.03 | 3.06 | 2.60 | 1.74 | 1.25 | 0.03 | 0.98 | -0.12 | 0.09 | 0.22 | -0.06 | -0.25 | 1.48 | 2.26 |
| EPS Growth % | -36.7% | -33.66% | 17.69% | 49.43% | 39.2% | 4270.63% | -97.08% | 916.67% | -233.33% | -59.09% | 454.84% | 75.2% | -116.89% | -34.51% | - |
| EPS (Basic) | - | 2.10 | 3.29 | 2.85 | 1.88 | 1.30 | 0.03 | 1.04 | -0.12 | 0.10 | 0.23 | -0.06 | -0.25 | 1.48 | 2.26 |
| Diluted Shares Outstanding | 44.23M | 48.22M | 52.06M | 53M | 52.43M | 49.78M | 49.12M | 49.91M | 46.4M | 48.37M | 47.5M | 44.96M | 41.96M | 8M | 8M |
| Basic Shares Outstanding | 43.64M | 46.74M | 48.43M | 48.27M | 48.55M | 47.78M | 47.04M | 46.98M | 46.4M | 46.11M | 45.38M | 44.96M | 41.96M | 8M | 8M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Quick answers to the most common questions about buying AMPH stock.
For fiscal year 2025, Amphastar Pharmaceuticals, Inc. (AMPH) reported total revenue of $719.9M. This represents a 252.3% increase compared to $204.3M in 2012.
Amphastar Pharmaceuticals, Inc. (AMPH) is profitable, generating $98.1M in net income for the fiscal year ending 2025 with a net profit margin of 13.6%.
Amphastar Pharmaceuticals, Inc. (AMPH) reported an operating income of $140.4M, resulting in an operating profit margin of 19.5%. This margin reflects the operational efficiency of the business before interest and taxes.
Amphastar Pharmaceuticals, Inc. (AMPH) generated $356.1M in gross profit for the year, representing a gross profit margin of 49.5%. This demonstrates the company's core pricing power and production efficiency.
Key Metrics
Top Statement Risk
Legacy generic pricing pressure
Metrics are mathematically derived from official filings.
Revenue Growth Stalls Amid Mix Shift
Revenue growth has decelerated to -1.7% YoY in 2025Q4, with 2026Q2 showing a modest 5.4% rebound, suggesting a transition phase as legacy generics face pricing headwinds.
The top line has been essentially flat over the past year, with quarterly growth oscillating between -4.4% and +5.4%. The recent uptick in 2026Q2 may reflect early contributions from new product launches, but the overall trend indicates that the portfolio is in a transition, with legacy products like enoxaparin likely experiencing volume and price erosion. The acquisition of Baqsimi is expected to shift the mix toward branded products, but its full impact on revenue growth is not yet visible in the reported figures.
Gross Margin Volatility Signals Mix Complexity
Gross margin swung from 54.0% in 2024Q3 to 41.1% in 2026Q1, reflecting product mix shifts and potential integration costs, before recovering to 50.8% in 2026Q2.
The wide range in gross margin suggests that the company's product mix is not stable, with high-margin proprietary products like Primatene Mist and Baqsimi potentially offset by lower-margin generics and API sales. The dip in 2026Q1 to 41.1% may indicate one-time costs or a temporary unfavorable mix, but the recovery to 50.8% in the following quarter suggests that the underlying margin structure remains intact. Investors should monitor whether the branded mix can sustain margins above 50% as the company scales its commercial infrastructure.
Operating Leverage Shows Signs of Strain
Operating margin compressed from 30.3% in 2024Q2 to 8.0% in 2026Q1, but rebounded to 21.6% in 2026Q2, indicating that SG&A and R&D costs are not scaling proportionally with revenue.
The operating margin volatility is more pronounced than gross margin, suggesting that operating expenses are not well controlled relative to revenue fluctuations. In 2025Q3, SG&A spiked to $51.0M, nearly double the typical level, which may reflect one-time charges or increased investment in the Baqsimi launch. The subsequent quarters show a return to more normal expense levels, but the lack of consistent operating leverage suggests that the company is investing heavily in its commercial infrastructure, which may pressure margins in the near term.
EPS Beat Masks Underlying Volatility
Q2 2026 EPS of $0.67 beat consensus by $0.06, but net income has swung from $43.2M in 2024Q1 to $6.4M in 2026Q1, indicating non-operating items and tax effects are significant.
The reported net income and EPS are highly volatile, with a 72.5% YoY decline in EPS in 2026Q1 followed by a recovery. This suggests that earnings quality is affected by one-time items, such as acquisition-related costs or tax benefits, rather than stable operational performance. The SBC expense has been relatively consistent at around $6-9M per quarter, which is not excessive, but the tax rate appears to fluctuate, as seen in the net margin varying from 25.1% to 3.8%. Investors should adjust for these non-operating items to assess the underlying profitability.
R&D and SG&A Investment Surge
R&D spending rose from $14.2M in 2024Q1 to $26.7M in 2026Q1, while SG&A spiked to $51.0M in 2025Q3, reflecting increased investment in pipeline and commercial capabilities.
The increase in R&D is consistent with the company's focus on complex generics and proprietary products, but the jump in SG&A in 2025Q3 is notable and may be tied to the Baqsimi acquisition and the build-out of a branded sales force. While these investments are necessary for long-term growth, they are currently compressing operating margins. The company's ability to manage these costs while scaling revenue will be critical to restoring operating leverage.
Baqsimi Acquisition Marks Strategic Pivot
The acquisition of Baqsimi in 2025 represents a pivotal shift from a generic-focused model to a branded specialty portfolio, with the full financial impact still unfolding.
The acquisition is likely to change the revenue mix and margin profile, but the reported data shows that gross margins have not yet consistently improved, and operating expenses have increased. The company's historical success with Primatene Mist suggests it can execute on complex products, but the integration of Baqsimi introduces new risks, including commercial execution and potential competition. The lasting impact will depend on whether the branded portfolio can offset the decline in legacy generics and deliver sustainable growth.
What Could Invalidate the Base Case
Despite the Q2 2026 EPS beat, revenue growth remains negative YoY, and the reliance on legacy generics exposes AMPH to continued pricing erosion that could undermine margin recovery.
Short-sellers might argue that the recent earnings beat is not sustainable, as it was driven by cost controls and one-time items rather than top-line growth. The flat-to-negative revenue trend, coupled with competitive pressures in the generic portfolio, suggests that the company may struggle to maintain margins if pricing pressures persist. Additionally, the integration of Baqsimi carries execution risk, and any failure to capture market share could lead to write-downs or margin compression. Investors should monitor whether the company can deliver consistent organic growth to justify its current valuation.