Last 34 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -10.37 | — | — | — | 1.54 | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 3.71 | 20.26 | 3.71 | 6.00 | 0.68 | 5.84 | 4.34 | 6.25 | 29.25 | — | 7.68 | 6.08 | 11.20 |
| — | +247.0% | -14.5% | -4.1% | -97.7% | — | -43.5% | +2.9% | +161.1% | — | -56.9% | -63.3% | -66.7% | |
| P/B Ratio | 1.98 | 1.77 | 1.10 | 0.88 | 0.77 | 2.46 | 3.03 | 3.19 | 4.85 | 3.81 | 2.32 | 2.86 | 2.85 |
| — | -27.9% | -63.7% | -72.4% | -84.1% | -35.4% | +30.4% | +11.6% | +70.4% | +18.3% | -39.0% | -14.4% | -42.2% | |
| P/FCF | — | — | — | — | — | — | — | 9.65 | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | 1.51 | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | 1.54 | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Arvinas, Inc.'s operating margin was -785.3% in Q4 2025, down 680.7 pp QoQ and down 687.0 pp YoY. The trailing four-quarter average of -292.8% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 6960.0% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | -151.8% | -6860.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 97.8% | 93.3% | 103.9% | 95.1% | 97.1% | 94.8% |
| — | -6960.0% | 0.0% | +2.3% | +7.2% | -3.8% | +5.2% | +0.7% | -1.6% | +10.0% | +1.5% | +2.8% | +2.9% | |
| Operating Margin | -45.1% | -785.3% | -104.5% | -319.2% | 37.8% | -98.3% | -58.9% | -63.4% | -329.2% | 383.5% | -213.6% | -136.9% | -269.8% |
| — | -698.8% | -77.5% | -403.5% | +111.5% | -125.6% | +72.4% | +53.7% | -22.0% | +293.3% | -10.3% | +29.7% | -23.9% | |
| Net Margin | -30.8% | -709.5% | -83.8% | -273.2% | 43.9% | -76.2% | -48.0% | -46.0% | -274.3% | 359.2% | -185.0% | -122.2% | -252.0% |
| — | -831.3% | -74.4% | -493.8% | +116.0% | -121.2% | +74.0% | +62.3% | -8.9% | +264.6% | +7.2% | +41.0% | -5.3% |
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -16.2% | -13.5% | -6.0% | -9.6% | 13.6% | -7.9% | -8.3% | -5.8% | -10.9% | -27.7% | -13.9% | -13.7% | -15.2% |
| — | -71.8% | +27.9% | -65.7% | +224.1% | +71.6% | +40.3% | +57.4% | +28.2% | -98.3% | -35.7% | -36.1% | -80.7% | |
| ROA | -8.9% | -8.6% | -4.0% | -6.4% | 7.9% | -4.0% | -4.0% | -2.8% | -5.5% | -13.1% | -6.0% | -5.9% | -6.7% |
| — | -116.1% | +0.5% | -126.8% | +243.7% | +69.5% | +32.7% | +52.1% | +17.7% | -105.8% | -23.8% | -21.9% | -62.2% | |
| ROIC | -23.1% | -14.5% | -6.7% | -9.8% | 10.1% | -9.0% | -9.5% | -7.5% | -14.3% | -35.5% | -15.3% | -14.7% | -15.0% |
| — | -61.6% | +29.4% | -31.0% | +170.8% | +74.7% | +37.7% | +48.9% | +5.1% | -208.6% | -71.0% | -85.9% | -133.9% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has improved 5.9% YoY to 4.92x, strengthening the short-term liquidity position.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.00 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 |
| — | +13.4% | +557.5% | +364.4% | +273.1% | +256.2% | -70.7% | -64.0% | -56.4% | -50.2% | -7.8% | +3.3% | +4.1% | |
| Debt / EBITDA | — | — | — | — | 0.14 | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 4.92 | 4.92 | 5.70 | 5.64 | 4.58 | 4.64 | 4.17 | 3.62 | 4.94 | 4.98 | 3.26 | 3.44 | 4.06 |
| — | +5.9% | +36.9% | +55.7% | -7.4% | -6.7% | +28.0% | +5.1% | +21.8% | +18.5% | -39.0% | -40.4% | -33.7% | |
| Quick Ratio | 4.92 | 4.92 | 5.70 | 5.64 | 4.58 | 4.64 | 4.17 | 3.62 | 4.94 | 4.98 | 3.26 | 3.44 | 4.06 |
| — | +5.9% | +36.9% | +55.7% | -7.4% | -6.7% | +28.0% | +5.1% | +21.8% | +18.5% | -39.0% | -40.4% | -33.7% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 34 years · Updated daily
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Start ComparisonArvinas, Inc.'s current P/E is -10.4x. The average P/E over the last 1 quarters is 1.5x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Arvinas, Inc.'s current operating margin is -45.1%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Arvinas, Inc.'s business trajectory between earnings reports.