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CASICASI Pharmaceuticals, Inc.
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CASI logoCASI Pharmaceuticals, Inc.(CASI)Earnings, Financials & Key Ratios

CASI•NASDAQ
Price updated May 1, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Specialty Pharma
AboutCASI Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes therapeutics and pharmaceutical products in China, the United States, and internationally. It offers EVOMELA, an intravenous formulation of melphalan for use as a conditioning treatment prior to stem cell transplantation, and as a palliative treatment for patients with multiple myeloma. The company's product pipeline includes CNCT19, an autologous CD19 CAR-T investigative product for the treatment of patients with B-cell acute lymphoblastic leukemia (B-ALL) and B-cell non-Hodgkin lymphoma (B-NHL); BI-1206 that is in Phase I/II trial in combination with anti-PD1 therapy Keytruda for solid tumors, and in a Phase I/IIa trial in combination with MabThera (rituximab) in patients with relapsed/refractory NHL; and CB-5339, which is in Phase I clinical trial for acute myeloid leukemia and myelodysplastic syndrome. Its product pipeline also comprises CID-103 for the treatment of patients with multiple myeloma; Thiotepa, which has multiple indications including use as a conditioning treatment for various allogeneic haemopoietic stem cell transplants; and Octreotide long acting injectable formulations for the treatment of acromegaly and for the control of symptoms associated with various neuroendocrine tumors. The company has licensing agreements with Juventas Cell Therapy Ltd; BioInvent International AB; Black Belt Therapeutics Limited; and Cleave Therapeutics, Inc. It also has distribution agreements with China Resources Pharmaceutical Commercial Group International Trading Co., Ltd; Pharmathen Global BV; and Riemser Pharma GmbH. The company was formerly known as EntreMed, Inc. and changed its name to CASI Pharmaceuticals, Inc. in June 2014. CASI Pharmaceuticals, Inc. was incorporated in 1991 and is based in Rockville, Maryland.Show more
  • Revenue$29M-15.8%
  • EBITDA-$37M-74.8%
  • Net Income-$39M-45.7%
  • EPS (Diluted)-2.56-26.7%
  • Gross Margin39.06%-34.0%
  • EBITDA Margin-130.67%-107.5%
  • Operating Margin-138.84%-87.6%
  • Net Margin-137.57%-73.0%
  • ROE-301.8%-410.3%

CASI Key Insights

CASI Pharmaceuticals, Inc. (CASI) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 47.2%
  • ✓Trading at only 1.2x book value

✗Weaknesses

  • ✗High debt to equity ratio of 12.0x
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 1 (bottom 1%)
  • ✗Shares diluted 14.8% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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CASI Price & Volume

CASI Pharmaceuticals, Inc. (CASI) stock price & volume — 10-year historical chart

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CASI Growth Metrics

CASI Pharmaceuticals, Inc. (CASI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years103.24%
5 Years47.19%
3 Years-1.84%
TTM21.72%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-59.58%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-41.7%

Return on Capital

10 Years-20.22%
5 Years-50.01%
3 Years-55.64%
Last Year-104.59%

CASI Peer Comparison

CASI Pharmaceuticals, Inc. (CASI) competitors in Commercial Specialty Pharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ZLAB logoZLABZai Lab LimitedDirect Competitor1.98B17.88-11.1815.33%-39.29%-24.32%0.31
LEGN logoLEGNLegend Biotech CorporationDirect Competitor6.2B33.52-20.9564.04%-21.97%-24.91%0.41
ZYME logoZYMEZymeworks Inc.Direct Competitor1.7B23.14-21.4338.87%-126.33%-0.25%0.07
CAN logoCANCanaan Inc.Direct Competitor209.89M0.33-0.7496.69%-39.68%-60.72%0.13
HALO logoHALOHalozyme Therapeutics, Inc.Product Competitor8.13B68.5726.7937.55%23.13%126.27%43.89
ACAD logoACADACADIA Pharmaceuticals Inc.Product Competitor3.7B21.609.4311.87%34.3%35.65%0.04
SUPN logoSUPNSupernus Pharmaceuticals, Inc.Product Competitor2.51B43.58-64.098.63%-3.74%-2.73%0.04
LXRX logoLXRXLexicon Pharmaceuticals, Inc.Product Competitor906.16M2.04-14.5760.24%-37.46%-18.64%0.58

Compare CASI vs Peers

CASI Pharmaceuticals, Inc. (CASI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ZLAB

Most directly comparable listed peer for CASI.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare CASI against a more recognizable public peer.

Peer Set

Compare Top 5

vs ZLAB, LEGN, ZYME, CAN

CASI Income Statement

CASI Pharmaceuticals, Inc. (CASI) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue
0004.13M15.14M30.17M43.11M33.88M28.54M26.85M
Revenue Growth %
-100%---266.52%99.25%42.89%-21.41%-15.77%21.72%
Cost of Goods Sold
66.45K117.78K1.67M3.94M9.51M12.56M15.83M13.83M17.39M17.23M
COGS % of Revenue
---95.26%62.8%41.62%36.72%40.81%60.94%-
Gross Profit
-66.45K▲ 0%
-117.78K▼ 77.2%
-1.67M▼ 1318.7%
196K▲ 111.7%
5.63M▲ 2774.0%
17.61M▲ 212.6%
27.28M▲ 54.9%
20.05M▼ 26.5%
11.15M▼ 44.4%
9.61M▲ 0%
Gross Margin %
---4.74%37.2%58.38%63.28%59.19%39.06%35.8%
Gross Profit Growth %
-260.36%-77.24%-1318.7%111.73%2773.98%212.64%54.9%-26.5%-44.41%-
Operating Expenses
9.42M10.75M26.5M40.19M58.41M59.13M53.77M45.13M50.77M54.71M
OpEx % of Revenue
---972.82%385.8%195.99%124.74%133.22%177.9%-
Selling, General & Admin
4.78M3.16M18M30.44M27.48M38.41M37.77M41.84M41.44M44.42M
SG&A % of Revenue
---736.84%181.47%127.31%87.63%123.49%145.23%-
Research & Development
4.65M7.6M8.51M9.75M11.47M14.42M16M9.86M8.92M8.74M
R&D % of Revenue
---235.97%75.75%47.81%37.11%29.11%31.25%-
Other Operating Expenses
000019.47M6.3M0-6.57M407K1.55M
Operating Income
9.42M▲ 0%
-10.75M▼ 214.1%
-26.5M▼ 146.5%
-39.99M▼ 50.9%
-52.78M▼ 32.0%
-41.52M▲ 21.3%
-26.49M▲ 36.2%
-25.08M▲ 5.3%
-39.62M▼ 58.0%
-45.09M▲ 0%
Operating Margin %
----968.07%-348.6%-137.62%-61.45%-74.03%-138.84%-167.98%
Operating Income Growth %
31.71%-214.13%-146.52%-50.88%-31.98%21.34%36.19%5.33%-57.98%-
EBITDA
9.49M-10.63M-24.83M-37.84M-50.82M-39.7M-24.07M-21.34M-37.29M-43.94M
EBITDA Margin %
----915.95%-335.66%-131.6%-55.84%-62.99%-130.67%-163.66%
EBITDA Growth %
31.39%-212.08%-133.54%-52.37%-34.31%21.88%39.37%11.34%-74.75%-59.97%
D&A (Non-Cash Add-back)
66.45K117.78K1.67M2.15M1.96M1.81M2.42M3.74M2.33M1.17M
EBIT
-9.42M-10.76M-27.46M-39.58M-33.31M-35.22M-26.49M-25.28M-37.2M-42.54M
Net Interest Income
-26.09K1.01K39.99K1.06M866K321K127K614K-332K-504K
Interest Income
7.72K15.98K48.2K1.06M866K321K189K614K539K132K
Interest Expense
33.81K14.98K8.21K00062K0871K636K
Other Income/Expense
-32.88K-18.88K-967.57K-5.37M5.27M5.67M-11.79M-1.21M1.55M-2.11M
Pretax Income
-9.45M▲ 0%
-10.77M▼ 13.9%
-27.47M▼ 155.1%
-45.36M▼ 65.1%
-47.51M▼ 4.7%
-35.84M▲ 24.6%
-38.28M▼ 6.8%
-26.29M▲ 31.3%
-38.07M▼ 44.8%
-47.2M▲ 0%
Pretax Margin %
----1098.09%-313.79%-118.81%-88.8%-77.61%-133.4%-175.83%
Income Tax
33.81K14.98K00001.98M-81K1.19M2.17M
Effective Tax Rate %
-0.36%-0.14%0%0%0%0%-5.17%0.31%-3.12%-4.61%
Net Income
-9.45M▲ 0%
-10.77M▼ 13.9%
-27.47M▼ 155.1%
-45.36M▼ 65.1%
-48.29M▼ 6.4%
-36.65M▲ 24.1%
-41.01M▼ 11.9%
-26.94M▲ 34.3%
-39.26M▼ 45.7%
-49.38M▲ 0%
Net Margin %
----1098.09%-318.92%-121.5%-95.14%-79.51%-137.57%-183.93%
Net Income Growth %
-31.18%-13.93%-155.07%-65.12%-6.45%24.09%-11.89%34.32%-45.73%-59.58%
Net Income (Continuing)
-9.45M-10.77M-27.47M-45.36M-47.51M-35.84M-40.26M-26.21M-39.26M-49.38M
Discontinued Operations
0000000000
Minority Interest
00020.67M22.03M23.46M22.36M000
EPS (Diluted)
-1.69▲ 0%
-1.75▼ 3.6%
-3.24▼ 85.1%
-4.80▼ 48.1%
-4.37▲ 9.0%
-2.69▲ 38.4%
-3.01▼ 11.9%
-2.02▲ 32.9%
-2.56▼ 26.7%
-3.08▲ 0%
EPS Growth %
23.87%-3.55%-85.14%-48.15%8.96%38.44%-11.9%32.89%-26.73%-41.7%
EPS (Basic)
-1.69-1.75-3.24-4.80-4.37-2.69-3.01-2.02-2.56-
Diluted Shares Outstanding
5.59M6.15M8.48M9.59M11.05M13.61M13.65M13.36M15.34M16.05M
Basic Shares Outstanding
5.59M6.15M8.48M9.59M11.05M13.61M13.65M13.36M15.34M16.05M
Dividend Payout Ratio
----------

CASI Balance Sheet

CASI Pharmaceuticals, Inc. (CASI) balance sheet — assets, liabilities & shareholders' equity

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets
27.45M43.81M92.56M61.5M74.03M61.97M73.42M59.34M39.58M11.91M
Cash & Short-Term Investments
27.09M43.49M85.12M54.25M66.37M48.57M51.34M30.77M16.09M4.68M
Cash Only
27.09M43.49M84.2M53.62M57.06M38.7M47.11M17.08M13.47M4.68M
Short-Term Investments
00912.2K625K9.31M9.87M4.22M13.69M2.62M0
Accounts Receivable
0001.29M4.64M9.8M12.97M10.14M15.35M2.61M
Days Sales Outstanding
---114.24111.98118.61109.85109.22196.27105.09
Inventory
00283K4.54M1.36M1.91M6.14M15.88M5.25M2.61M
Days Inventory Outstanding
--61.82421.352.0655.43141.55419.12110.2381.6
Other Current Assets
355.89K322.49K911.81K0002.98M2.56M2.89M0
Total Non-Current Assets
264.08K1.29M20.85M41.13M53.71M76.33M22.81M15.92M13.9M12.55M
Property, Plant & Equipment
229.59K1.05M1.75M9.69M10.76M21.82M13.23M11.63M11.36M9.95M
Fixed Asset Turnover
---0.43x1.41x1.38x3.26x2.91x2.51x2.52x
Goodwill
0000000000
Intangible Assets
0018.78M16.89M13.21M12.2M1.06M1.84M238K224K
Long-Term Investments
00014.04M29.44M40.13M7.46M1.68M1.72M7.06M
Other Non-Current Assets
34.48K242.02K310.02K504K299K2.18M1.06M771K587K660K
Total Assets
27.71M▲ 0%
45.1M▲ 62.7%
113.41M▲ 151.5%
102.63M▼ 9.5%
127.73M▲ 24.5%
138.3M▲ 8.3%
96.23M▼ 30.4%
75.27M▼ 21.8%
53.67M▼ 28.7%
24.46M▲ 0%
Asset Turnover
---0.04x0.12x0.22x0.45x0.45x0.53x0.72x
Asset Growth %
375.65%62.74%151.46%-9.5%24.46%8.27%-30.42%-21.79%-28.69%-159.01%
Total Current Liabilities
1.32M5.06M3.87M7.95M7.98M13.19M17M16.73M36.45M39.42M
Accounts Payable
1.06M2.09M968K5.11M3.26M4.79M3.29M4.44M2.72M560K
Days Payables Outstanding
5.85K6.47K211.45474.27125.15139.275.85117.1557.1527.97
Short-Term Debt
001.5M01.29M2.17M0018.39M18.86M
Deferred Revenue (Current)
0000002.62M2.54M2.47M2.47M
Other Current Liabilities
02.23M944-1.18M0-7.62M0010.31M0
Current Ratio
20.86x8.65x23.89x7.74x9.28x4.70x4.32x3.55x1.09x0.30x
Quick Ratio
20.86x8.65x23.82x7.17x9.11x4.56x3.96x2.60x0.94x0.24x
Cash Conversion Cycle
---61.2838.8834.83175.55411.19249.35158.72
Total Non-Current Liabilities
5.61M1.5M73.59K1.02M16.18M17.15M12.3M34.38M15.37M13.63M
Long-Term Debt
1.49M1.5M0000018.89M00
Capital Lease Obligations
0001.02M965K1.1M476K1.62M2.54M2.54M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
4.12M073.59K012.87M13.22M11.82M13.87M12.84M13.63M
Total Liabilities
6.93M6.56M3.95M8.97M24.16M30.34M29.3M51.1M51.82M53.05M
Total Debt
1.49M1.5M1.5M2.2M3.2M4.33M1.34M21.24M22.14M18.86M
Net Debt
-25.6M-41.99M-82.71M-51.42M-53.87M-34.37M-45.77M4.16M8.67M14.17M
Debt / Equity
0.07x0.04x0.01x0.02x0.03x0.04x0.02x0.88x11.96x-0.66x
Debt / EBITDA
0.16x---------0.43x
Net Debt / EBITDA
-2.70x---------0.32x
Interest Coverage
-278.62x-718.16x-3345.93x----427.27x--42.71x-66.88x
Total Equity
20.78M▲ 0%
38.54M▲ 85.4%
109.46M▲ 184.0%
93.67M▼ 14.4%
103.57M▲ 10.6%
107.96M▲ 4.2%
66.93M▼ 38.0%
24.16M▼ 63.9%
1.85M▼ 92.3%
-28.59M▲ 0%
Equity Growth %
441.42%85.43%184.02%-14.43%10.58%4.23%-38%-63.9%-92.34%-876.14%
Book Value per Share
3.726.2712.929.769.387.934.901.810.12-1.78
Total Shareholders' Equity
20.78M38.54M109.46M73M81.54M84.5M44.57M24.16M1.85M-28.59M
Common Stock
602.76K699.01K953.67K979K1.24M1.4M1K1K2K2K
Retained Earnings
-441.93M-452.7M-478.94M-523.91M-570.5M-605.64M-637.16M-660.82M-700.08M-735.09M
Treasury Stock
-8.03M-8.03M-8.03M-8.03M-8.03M-8.03M-9.33M-9.6M-9.6M-9.6M
Accumulated OCI
-262.02K-372.27K-1.23M-2.73M589K1.95M-703K-1.2M-1.77M-5.14M
Minority Interest
00020.67M22.03M23.46M22.36M000

CASI Cash Flow Statement

CASI Pharmaceuticals, Inc. (CASI) cash flow — operating, investing & free cash flow history

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations
-6.02M-6.4M-28.58M-23.24M-25.89M-26.84M-21.09M-19.97M-29.22M0
Operating CF Margin %
----562.65%-170.97%-88.98%-48.92%-58.94%-102.41%-
Operating CF Growth %
-9.24%-6.29%-346.47%18.69%-11.37%-3.69%21.44%5.32%-46.36%0%
Net Income
-9.45M-10.77M-27.47M-45.36M-47.51M-35.84M-40.26M-26.94M-39.26M-49.38M
Depreciation & Amortization
66.45K117.78K1.67M2.15M1.96M1.81M2.42M3.74M2.33M0
Stock-Based Compensation
3M650.44K6.12M7.31M7.82M7.77M7.01M7.22M1.31M1.31M
Deferred Taxes
-5.67K19.89K325.46K1.24M-3.94M-5.2M0000
Other Non-Cash Items
26.31K7.48K553.57K6.97M19.1M7.83M16.39M3.83M5.63M48.07M
Working Capital Changes
348.04K3.57M-9.78M4.45M-3.32M-3.22M-6.65M-7.82M771K0
Change in Receivables
000-1.29M-3.35M-5.16M-3.17M2.83M-5.21M0
Change in Inventory
00-283K-4.41M3.19M-551K-4.23M-9.74M5.83M0
Change in Payables
180.53K849.37K-1.1M4M-1.54M1.49M1.07M1.15M-1.72M0
Cash from Investing
-64.79K-934.7K-21.77M-28.06M-20.72M-20.69M31.16M-9.67M11.24M0
Capital Expenditures
-223.23K-934.7K-21.77M-14.02M-19.33M-15.5M-5.61M-204K-223K0
CapEx % of Revenue
---339.39%127.65%51.38%13.02%0.6%0.78%0%
Acquisitions
158.45K0-20.64M20M010K138K0-1.37M0
Investments
----------
Other Investing
158.45K020.64M-6.97M-1.31M7.03M6.44M-2.04M483K0
Cash from Financing
28.05M23.73M92.27M22.05M47.15M29.64M-3.27M-907K15.43M0
Debt Issued (Net)
0326K258K-1.5M1.25M-839K0000
Equity Issued (Net)
28.15M23.87M87.99M182K45.1M32.5M-3.27M-169K15M0
Dividends Paid
0000000-738K-718K0
Share Repurchases
000000-3.27M-278K00
Other Financing
-96.51K-462.84K4.02M23.36M805K-2.02M001.15M0
Net Change in Cash
21.96M▲ 0%
16.4M▼ 25.3%
40.71M▲ 148.3%
-30.58M▼ 175.1%
3.44M▲ 111.3%
-18.36M▼ 633.3%
8.41M▲ 145.8%
-30.03M▼ 457.1%
-3.62M▲ 88.0%
-11.85M▲ 0%
Free Cash Flow
-6.25M▲ 0%
-7.34M▼ 17.5%
-50.36M▼ 586.4%
-37.26M▲ 26.0%
-45.21M▼ 21.3%
-42.34M▲ 6.3%
-26.7M▲ 36.9%
-22.21M▲ 16.8%
-29.46M▼ 32.7%
0▲ 0%
FCF Margin %
----902.03%-298.61%-140.35%-61.94%-65.55%-103.25%0%
FCF Growth %
-12.77%-17.46%-586.36%26%-21.33%6.35%36.94%16.82%-32.67%-
FCF per Share
-1.12-1.19-5.94-3.88-4.09-3.11-1.96-1.66-1.920.00
FCF Conversion (FCF/Net Income)
0.64x0.59x1.04x0.51x0.54x0.73x0.51x0.74x0.74x-0.00x
Interest Paid
0000000000
Taxes Paid
00000001.81M00

CASI Key Ratios

CASI Pharmaceuticals, Inc. (CASI) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)
-128.65%-36.31%-37.12%-44.66%-48.96%-34.66%-46.9%-59.14%-301.8%358.32%
Return on Invested Capital (ROIC)
---170.59%-86.93%-86.1%-50.51%-41.94%-76.02%-153%1066.16%
Gross Margin
---4.74%37.2%58.38%63.28%59.19%39.06%35.8%
Net Margin
----1098.09%-318.92%-121.5%-95.14%-79.51%-137.57%-183.93%
Debt / Equity
0.07x0.04x0.01x0.02x0.03x0.04x0.02x0.88x11.96x-0.66x
Interest Coverage
-278.62x-718.16x-3345.93x----427.27x--42.71x-66.88x
FCF Conversion
0.64x0.59x1.04x0.51x0.54x0.73x0.51x0.74x0.74x-0.00x
Revenue Growth
-100%---266.52%99.25%42.89%-21.41%-15.77%21.72%
Related:CASI Dividend History·CASI Revenue History·CASI Price History·CASI P/E History·CASI Financial Ratios·CASI Institutional Holders

CASI SEC Filings & Documents

CASI Pharmaceuticals, Inc. (CASI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 21, 2023·SEC

Material company update

Jan 31, 2023·SEC

Material company update

Nov 14, 2022·SEC

10-K Annual Reports

1
FY 2022

Mar 28, 2022·SEC

10-Q Quarterly Reports

4
FY 2022

Nov 14, 2022·SEC

FY 2022

Aug 12, 2022·SEC

FY 2022

May 12, 2022·SEC

CASI Frequently Asked Questions

CASI Pharmaceuticals, Inc. (CASI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

CASI Pharmaceuticals, Inc. (CASI) reported $26.8M in revenue for fiscal year 2024. This represents a 3629% increase from $0.7M in 1995.

CASI Pharmaceuticals, Inc. (CASI) saw revenue decline by 15.8% over the past year.

CASI Pharmaceuticals, Inc. (CASI) reported a net loss of $49.4M for fiscal year 2024.

Dividend & Returns

Yes, CASI Pharmaceuticals, Inc. (CASI) pays a dividend with a yield of 31.10%. This makes it attractive for income-focused investors.

CASI Pharmaceuticals, Inc. (CASI) has a return on equity (ROE) of -301.8%. Negative ROE indicates the company is unprofitable.

CASI Pharmaceuticals, Inc. (CASI) had negative free cash flow of $29.5M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in CASI back in 1995?

Total return calculator · dividends reinvested · 31+ years of data

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How much would $100/month in CASI be worth today?

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