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CBIOCrescent Biopharma, Inc.$18.34$506M
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CBIO logoCrescent Biopharma, Inc. (CBIO) Earnings History

Net Loss

15 years of earnings data (2011–2025) · Currently unprofitable on a TTM basis

TTM Net Income
-$162M
● Net Loss
TTM EPS (Diluted)
$-5.33
Per share, diluted
YoY EPS Growth
-815.0%
Declining
Net Margin
-1419.6%
After-tax profitability
EPS Growth Rate (CAGR)
1YN/A
3YN/A
5YN/A
10YN/A
Operating Margin-1407.5%
Gross Margin100.0%
Return on Equity-164.2%
Return on Assets-111.6%
Record Annual Net Income$4MFY2012
Record Quarterly EPS$0.51Q2 2015
Consecutive Profitable Years0years
Q1 2026
Net Income-$23M
EPS (Diluted)$-0.70
YoY Growth-815.0%Declining
QoQ Growth+74.8%Excellent

Loading earnings history...

Crescent Biopharma, Inc. (CBIO) Earnings Overview

As of June 12, 2026, Crescent Biopharma, Inc. (CBIO) reported trailing twelve-month net income of -$162M, reflecting -815.0% year-over-year growth. The company earned $-5.33 per diluted share over the past four quarters, with a net profit margin of -1419.6%.

Looking at the long-term picture, CBIO's historical earnings data spans multiple years. The company achieved its highest annual net income of $4M in fiscal 2012.

Crescent Biopharma, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including RCUS (-$369M net income, -142.9% margin), IMVT (-$506M net income), KYMR (-$315M net income, -794.4% margin), CBIO has room to improve margins relative to the peer group. Compare CBIO vs RCUS →

CBIO Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
CBIO logoCBIOCurrent
-$162M$-5.33-1419.6%-164.2%-815.0%—
RCUS logoRCUS
-$369M$-2.94-142.9%-63.3%-4.8%
IMVT logoIMVT
-$506M$-2.48--64.8%-1.5%
KYMR logoKYMR
-$315M$-3.23-794.4%-25.8%-23.8%
TPST logoTPST
-$43M$-3.94--203.6%-322.0%
AGEN logoAGEN
$65M$1.690.1%-+100.0%
Best in group
Lowest in group

CBIO Historical Earnings Data (2011–2025)

15 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$154M-217.3%-$153M$-12.81-1419.6%-1407.5%
2024-$49M-31.5%-$50M$-1.40--
2023-$37M+21.0%-$39M$-0.58-368994.2%-392752.9%
2022-$47M+26.4%-$47M$-0.89-62251.7%-63204.4%
2021-$63M-24.3%-$63M$-1.23-5469.0%-5470.7%
2020-$51M+5.7%-$52M$-1.12-502.1%-506.8%
2019-$54M-12.1%-$61M$-1.34--
2018-$48M-45.0%-$52M$-1.18--
2017-$33M-4.6%-$34M$-1.13--
2016-$32M-149.1%-$32M$-1.50-171945.1%-172505.3%
2015-$13M-14.8%-$13M$-0.67-63.6%-63.7%
2014-$11M-4.9%-$11M$-0.60-74.0%-74.1%
2013-$11M-390.1%-$11M$-8.87-265.6%-265.7%
2012$4M+159.8%$4M$3.0624.0%23.8%
2011-$6M--$6M$-5.11-160.3%-159.5%

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What if you invested $1,000 in CBIO back in 2011?

Total return with dividends reinvested · 15+ years of data

Calculate Returns

How much would $100/month in CBIO be worth today?

Dollar cost averaging vs lump sum · see how regular investing compounds over time

Run the Numbers

Is CBIO Undervalued Right Now?

DCF intrinsic value, peer multiples, and analyst estimates — see what the stock is really worth.

View Valuation

CBIO vs LLY — which is the better buy?

Side-by-side revenue, margins, P/E and 10-year returns vs Eli Lilly and Company.

Compare Now

CBIO — Frequently Asked Questions

Quick answers to the most common questions about buying CBIO stock.

What is CBIO earnings per share (EPS)?

CBIO trailing twelve-month (TTM) diluted EPS is $-5.33, reflecting -815.0% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2011 to 2025 is available in the table on this page.

What is Crescent Biopharma, Inc.'s net income?

Crescent Biopharma, Inc. (CBIO) trailing twelve-month net income is $-162M as of 2025. Earnings declined -815.0% year-over-year.

Is CBIO profitable?

CBIO is not currently profitable on a TTM basis, reporting a net loss of $-162M. Net margin is -1419.6%. Investors should monitor for a return to profitability.

What is CBIO's earnings growth rate?

CBIO compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2011 to 2025.

What are CBIO's profit margins?

Crescent Biopharma, Inc. net profit margin is -1419.6%, operating margin is -1407.5%, and gross margin is +100.0%. Below-average margins reflect competitive or cost pressures. Return on Equity is -164.2%.

Is CBIO growing earnings?

CBIO earnings are declining — EPS fell -815.0% year-over-year. TTM net income dropped to $-162M. This contrasts with the 5-year CAGR of N/A.

What was CBIO's best earnings year?

Crescent Biopharma, Inc.'s highest annual net income on record is $4M, achieved in fiscal year 2012. Earnings history on this page spans 2011 to 2025 and includes all annual and quarterly figures.

What were CBIO's earnings last quarter?

CBIO's most recent reported quarter was Q1 2026. Net income was $-23M with diluted EPS of $-0.70. For a full breakdown of all quarters, see the quarterly earnings table on this page.

CBIO Earnings Over Time (2011–2025)

Net income & EPS — annual and quarterly view