Last 22 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -27.21 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 409.72 | — | — | — | — | 31.88 | — | — | — | — | 28.44 | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/B Ratio | 10.23 | 12.51 | 6.44 | 10.79 | 5.09 | 4.95 | 5.51 | 3.72 | 3.45 | 5.25 | 3.30 | 2.41 | 2.13 |
| — | +152.7% | +17.0% | +189.7% | +47.8% | -5.6% | +66.9% | +54.5% | +61.8% | +320.9% | +278.2% | +137.1% | +95.2% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | — | — | — | — | 100.0% | — | — | — | — | 100.0% | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Operating Margin | -1384.6% | — | — | — | — | -205.2% | — | — | — | — | -513.3% | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Net Margin | -1316.9% | — | — | — | — | -174.2% | — | — | — | — | -537.5% | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -42.6% | -15.6% | -16.0% | -17.0% | -13.8% | -6.6% | -24.7% | -10.8% | -17.5% | -16.9% | -14.9% | -14.4% | -8.7% |
| — | -135.5% | +35.4% | -56.8% | +21.1% | +60.6% | -66.3% | +24.9% | -99.8% | -4.6% | -22.1% | -6.1% | +39.2% | |
| ROA | -31.2% | -11.9% | -11.7% | -11.7% | -9.9% | -4.7% | -18.8% | -8.4% | -12.1% | -11.1% | -10.0% | -10.0% | -6.2% |
| — | -152.0% | +37.9% | -38.3% | +18.1% | +57.2% | -87.9% | +15.9% | -93.0% | +7.6% | -6.8% | +6.8% | +46.7% | |
| ROIC | -51.2% | -13.2% | -12.2% | -10.2% | -10.0% | -8.6% | -34.5% | -16.0% | -15.4% | -14.4% | -14.5% | -15.6% | -21.4% |
| — | -53.1% | +64.6% | +36.1% | +34.9% | +40.1% | -138.0% | -2.5% | +28.2% | +75.1% | +98.0% | — | +97.1% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 33.6% YoY to 9.53x, tightening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.01 | 0.02 | 0.01 | 0.39 | 0.34 | 0.31 | 0.29 | 0.17 | 0.30 | 0.40 | 0.36 | 0.32 | 0.30 |
| — | -95.0% | -95.1% | +131.0% | +14.8% | -23.6% | -18.5% | -47.3% | -0.4% | +44.3% | +72.4% | +76.0% | +86.8% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 8.57 | 9.53 | 8.57 | 10.57 | 10.12 | 14.37 | 9.25 | 21.52 | 13.29 | 10.37 | 8.00 | 9.51 | 10.35 |
| — | -33.6% | -7.4% | -50.9% | -23.9% | +38.6% | +15.6% | +126.3% | +28.4% | -19.9% | -29.9% | -23.8% | -33.1% | |
| Quick Ratio | 8.57 | 9.53 | 8.57 | 10.57 | 10.12 | 14.37 | 9.25 | 21.52 | 13.29 | 10.37 | 8.00 | 9.51 | 10.35 |
| — | -33.6% | -7.4% | -50.9% | -23.9% | +38.6% | +15.6% | +126.3% | +28.4% | -17.4% | -29.9% | -22.4% | -31.5% | |
| Interest Coverage | -18.12 | -29.21 | -31.10 | -17.94 | -16.19 | -7.60 | -43.49 | -15.41 | -16.07 | -13.85 | -12.89 | -15.32 | -18.97 |
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Includes 30+ ratios · 22 years · Updated daily
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Centessa Pharmaceuticals plc's current P/E is -27.2x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Centessa Pharmaceuticals plc's current operating margin is -1384.6%. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Centessa Pharmaceuticals plc's business trajectory between earnings reports.