57% buyers of institutions opening or closing positions this quarter
12 more new buyers than exits, ownership rose 38.90 percentage points vs the prior quarter, and no widely-followed fund managers in the top 25.
57% buyers of institutions opening or closing positions this quarter
95.8% institutional ownership
Index Venture Life portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in CNTA across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CNTA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Medicxi Ventures Management (Jersey) Ltd | 20.0M | $792.9M | 0.0% | 12.902% | 80.76% |
| 2 | Avoro Capital Advisors LLC | 11.4M | $454.0M | -21.5% | 7.387% | 4.47% |
| 3 | Index Venture Life Associates VI Ltd | 10.0M | $395.7M | 0.0% | 6.438% | 100.00% |
| 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 8.9M | $354.5M | -20.9% | 5.768% | 0.55% |
| 5 | Pentwater Capital Management LP | 8.2M | $324.5M | β | 5.280% | 1.68% |
| 6 | FMR LLC | 6.9M | $272.2M | -23.5% | 4.428% | 0.01% |
| 7 | EcoR1 Capital, LLC | 6.4M | $254.6M | +105.8% | 4.143% | 10.81% |
| 8 | PERCEPTIVE ADVISORS LLC | 5.3M | $208.9M | +80.3% | 3.399% | 4.09% |
| 9 | Capital World Investors | 4.8M | $191.9M | +317.1% | 3.123% | 0.03% |
| 10 | FARALLON CAPITAL MANAGEMENT LLC | 4.8M | $191.0M | -10.6% | 3.108% | 1.09% |
| 11 | TCG Crossover Management, LLC | 4.3M | $170.3M | 0.0% | 2.770% | 4.87% |
| 12 | MORGAN STANLEY | 4.3M | $169.5M | +284.9% | 2.759% | 0.01% |
| 13 | Paradigm Biocapital Advisors LP | 3.6M | $142.0M | β | 2.310% | 2.90% |
| 14 | JANUS HENDERSON GROUP PLC | 3.5M | $138.7M | -14.7% | 2.258% | 0.07% |
| 15 | Deep Track Capital, LP | 3.2M | $125.4M | +57.9% | 2.041% | 2.05% |
| 16 | Logos Global Management LP | 2.1M | $84.4M | +962.5% | 1.373% | 4.21% |
| 17 | RTW INVESTMENTS, LP | 2.1M | $81.6M | +14.7% | 1.328% | 0.81% |
| 18 | FEDERATED HERMES, INC. | 2.0M | $81.4M | -12.5% | 1.325% | 0.13% |
| 19 | BRAIDWELL LP | 2.0M | $78.9M | -9.2% | 1.284% | 2.63% |
| 20 | BANK OF AMERICA CORP /DE/ | 1.9M | $76.8M | +103.5% | 1.249% | 0.01% |
| 21 | MAVERICK CAPITAL LTD | 1.9M | $73.7M | +12.8% | 1.199% | 0.85% |
| 22 | First Light Asset Management, LLC | 1.6M | $62.0M | -31.5% | 1.009% | 5.56% |
| 23 | Affinity Asset Advisors, LLC | 1.4M | $55.6M | +133.1% | 0.905% | 2.87% |
| 24 | Foresite Capital Management VI LLC | 1.4M | $54.2M | 0.0% | 0.882% | 11.77% |
| 25 | GENERAL ATLANTIC, L.P. | 1.4M | $53.8M | -77.8% | 0.876% | 2.50% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in CNTA β a direct measure of their conviction.
Filings activity in CNTA during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new CNTA position in Q1 2026
Institutions that fully closed their CNTA position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 158 | +8.2% | 95.78% | +38.90 pp | $5.90B | +68% |
| Q4 2025 | 146 | +19% | 56.88% | +8.57 pp | $3.50B | +18% |
| Q3 2025 | 123 | +4.2% | 48.31% | +23.20 pp | $2.97B | +92% |
| Q2 2025 | 118 | 8.5% | 25.11% | 2.00 pp | $1.55B | 7.4% |
| Q1 2025 | 129 | +13% | 27.11% | 3.50 pp | $1.67B | 11% |
| Q4 2024 | 114 | +12% | 30.61% | +4.76 pp | $1.88B | +18% |
| Q3 2024 | 102 | +28% | 25.85% | +13.83 pp | $1.59B | +115% |
| Q2 2024 | 80 | β | 12.02% | β | $740M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for CNTA.
Quick answers to the most common questions about buying CNTA stock.
Based on Q1 2026 13F filings, institutional ownership of Centessa Pharmaceuticals plc stands at 95.8%, held across 158 reporting institutions.
Medicxi Ventures Management (Jersey) Ltd is the largest reported institutional holder of CNTA, with approximately 19,963,157 shares worth $0.79B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of CNTA.
Our composite Smart Money Score for CNTA is 47 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
48 institutions opened new positions in CNTA during Q1 2026, while 36 fully exited. 86 added to existing positions and 24 trimmed.
CNTA institutional ownership rose by 38.90 percentage points quarter-over-quarter, with a net change of β holders.
The top 10 institutions account for 58.4% of all reported 13F value in CNTA, and the top 25 account for 82.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.