Last 23 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -1.81 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 3.92 | 4.69 | 3.45 | 5.22 | 3.11 | 1.60 | 2.91 | 1.20 | 3.06 | 15.28 | 24.06 | 15.93 | 11.16 | 7.90 | 7.98 | 19.16 | 6.67 | 9.62 | 21.43 | 49.41 | 73.76 |
| — | +193.0% | +18.7% | +336.8% | +1.8% | -89.5% | -87.9% | -92.5% | -72.6% | +93.5% | +201.4% | -16.9% | +67.3% | -17.9% | -62.8% | -61.2% | -91.0% | — | — | — | — | |
| P/B Ratio | 1.11 | 0.82 | 0.91 | 1.45 | 1.01 | 0.48 | 0.71 | 0.53 | 0.82 | 2.35 | 3.05 | 2.82 | 2.39 | 1.59 | 1.81 | 3.53 | 2.46 | 4.01 | 8.12 | 9.48 | 36.18 |
| — | +72.5% | +27.3% | +171.5% | +22.1% | -79.7% | -76.7% | -81.1% | -65.5% | +48.2% | +68.7% | -20.2% | -2.8% | -60.5% | -77.7% | -62.7% | -93.2% | — | — | — | — | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 81.5% | 18.4% | 124.4% | 67.0% | 70.1% | 75.1% | 78.1% | 88.8% | 75.6% | 75.7% | 81.0% | 87.5% | 77.5% | 72.3% | 69.3% | 62.9% | 55.8% | 49.3% | 55.2% | 71.3% | 60.8% |
| — | -75.5% | +59.4% | -24.5% | -7.2% | -0.9% | -3.6% | +1.5% | -2.5% | +4.8% | +16.9% | +39.2% | +38.9% | +46.7% | +25.5% | -11.8% | -8.2% | +6.5% | -2.9% | -28.7% | — | |
| Operating Margin | -185.3% | -366.5% | -211.9% | -231.8% | -132.1% | -184.1% | -236.3% | -62.0% | -396.7% | -469.1% | -512.5% | -516.7% | -228.6% | -267.3% | -238.6% | -986.4% | -447.9% | -401.0% | -1134.5% | -34.4% | -137.4% |
| — | -99.0% | +10.3% | -273.9% | +66.7% | +60.7% | +53.9% | +88.0% | -73.5% | -75.5% | -114.8% | +47.6% | +49.0% | +33.3% | +79.0% | -2770.2% | -226.1% | -209.6% | -550.8% | +53.6% | — | |
| Net Margin | -183.8% | -424.1% | -241.8% | -207.9% | -121.6% | -188.2% | -245.2% | -63.3% | -386.4% | -437.3% | -609.1% | -546.4% | -215.1% | -254.0% | -179.6% | -1009.3% | -462.5% | -350.6% | -1077.9% | -131.3% | -123.6% |
| — | -125.3% | +1.4% | -228.3% | +68.5% | +56.9% | +59.7% | +88.4% | -79.6% | -72.2% | -239.1% | +45.9% | +53.5% | +27.6% | +83.3% | -668.8% | -274.1% | -110.2% | -636.4% | -11.1% | — |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -51.1% | -17.4% | -15.1% | -13.8% | -9.6% | -13.3% | -14.2% | -6.9% | -23.9% | -15.9% | -18.0% | -22.0% | -11.1% | -12.3% | -11.1% | -44.6% | -42.0% | -37.1% | -100.5% | -10.3% | -14.4% |
| — | -30.1% | -6.4% | -99.1% | +59.9% | +16.2% | +21.2% | +68.5% | -114.2% | -29.9% | -62.1% | +50.7% | +73.5% | +67.0% | +88.9% | -331.8% | -192.9% | -118.4% | -940.8% | -107.5% | — | |
| ROA | -25.0% | -7.7% | -7.0% | -6.7% | -4.8% | -6.8% | -7.5% | -3.6% | -13.5% | -10.2% | -11.5% | -14.0% | -7.4% | -8.3% | -8.0% | -34.7% | -33.0% | -28.6% | -75.8% | -7.4% | -8.8% |
| — | -12.7% | +7.0% | -83.8% | +64.7% | +33.4% | +34.4% | +74.1% | -84.0% | -23.6% | -43.2% | +59.5% | +77.7% | +71.1% | +89.4% | -365.9% | -276.6% | -156.4% | -991.1% | — | — | |
| ROIC | -34.3% | -7.3% | -6.5% | -7.9% | -6.1% | -9.6% | -12.4% | -7.0% | -35.8% | -34.7% | -26.7% | -30.3% | -17.1% | -19.4% | -33.2% | -224.1% | -249.3% | -536.6% | -3127.2% | -127.3% | -37.4% |
| — | +24.0% | +47.7% | -12.8% | +82.9% | +72.3% | +53.5% | +76.9% | -109.5% | -78.7% | +19.4% | +86.5% | +93.1% | +96.4% | +98.9% | -76.1% | -565.6% | -1216.2% | -41060.6% | -10698.9% | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.82 | 0.93 | 0.82 | 0.76 | 0.70 | 0.67 | 0.65 | 0.56 | 0.54 | 0.24 | 0.22 | 0.32 | 0.27 | 0.25 | 0.25 | 0.04 | 0.03 | 0.02 | 0.01 | 0.01 | 0.05 |
| — | +38.1% | +25.5% | +35.3% | +28.9% | +182.6% | +199.5% | +73.3% | +98.6% | -5.5% | -14.4% | +675.3% | +730.9% | +1385.6% | +1634.9% | +313.4% | -28.5% | -59.3% | -59.4% | — | — | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 4.92 | 5.15 | 4.92 | 4.39 | 5.41 | 4.88 | 5.62 | 5.79 | 4.71 | 5.34 | 6.11 | 6.78 | 7.49 | 6.92 | 8.38 | 11.71 | 11.84 | 10.71 | 12.79 | 20.05 | 3.50 |
| — | +5.5% | -12.5% | -24.2% | +14.7% | -8.6% | -8.1% | -14.6% | -37.1% | -22.8% | -27.1% | -42.1% | -36.7% | -35.4% | -34.4% | -41.6% | +238.0% | +192.8% | +119.5% | — | — | |
| Quick Ratio | 4.92 | 5.15 | 4.92 | 4.39 | 5.41 | 4.88 | 5.62 | 5.79 | 4.71 | 5.34 | 6.11 | 6.78 | 7.49 | 6.91 | 8.36 | 11.67 | 11.78 | 10.66 | 12.76 | 20.01 | 3.47 |
| — | +5.5% | -12.5% | -24.2% | +14.7% | -8.6% | -8.1% | -14.6% | -37.0% | -22.7% | -26.9% | -41.9% | -36.4% | -35.2% | -34.5% | -41.7% | +239.6% | +194.1% | +123.9% | — | — | |
| Interest Coverage | — | — | — | — | — | — | -1692.94 | — | — | — | -3255.57 | — | — | — | — | — | — | -1701.19 | -2913.12 | -41.10 | -125.41 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 23 years · Updated daily
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Ginkgo Bioworks Holdings, Inc.'s current P/E is -1.8x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Ginkgo Bioworks Holdings, Inc.'s current operating margin is -185.3%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Ginkgo Bioworks Holdings, Inc.'s business trajectory between earnings reports.