52% buyers of institutions opening or closing positions this quarter
1 more new buyers than exits, ownership rose 0.00 percentage points vs the prior quarter, and no widely-followed fund managers in the top 25.
52% buyers of institutions opening or closing positions this quarter
200.0% institutional ownership
FCPM III SERVICES portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in ENGN across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ENGN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FCPM III SERVICES B.V. | 9.6M | $65.6M | 0.0% | 18.815% | 9.08% |
| 2 | PERCEPTIVE ADVISORS LLC | 5.8M | $39.7M | -0.7% | 11.383% | 0.78% |
| 3 | Siren, L.L.C. | 5.3M | $35.8M | +57.5% | 10.261% | 0.99% |
| 4 | VR Adviser, LLC | 4.8M | $32.5M | 0.0% | 9.320% | 1.21% |
| 5 | Blue Owl Capital Holdings LP | 4.4M | $30.1M | +31.4% | 8.627% | 8.08% |
| 6 | Deep Track Capital, LP | 4.4M | $29.8M | 0.0% | 8.551% | 0.49% |
| 7 | BRAIDWELL LP | 2.5M | $16.7M | -21.5% | 4.799% | 0.56% |
| 8 | Nextech Invest, Ltd. | 2.3M | $15.8M | +9.4% | 4.541% | 1.11% |
| 9 | Vestal Point Capital, LP | 2.2M | $14.7M | +105.2% | 4.229% | 0.41% |
| 10 | MPM Oncology Impact Management LP | 1.8M | $12.6M | +0.2% | 3.605% | 0.97% |
| 11 | Kynam Capital Management, LP | 1.4M | $9.2M | -9.1% | 2.650% | 0.57% |
| 12 | FRANKLIN RESOURCES INC | 1.3M | $9.0M | -5.3% | 2.569% | 0.00% |
| 13 | Polar Capital Holdings Plc | 1.2M | $8.3M | +7.1% | 2.391% | 0.03% |
| 14 | BALYASNY ASSET MANAGEMENT LLC | 1.1M | $7.8M | — | 2.244% | 0.01% |
| 15 | MILLENNIUM MANAGEMENT LLC | 960K | $6.5M | -36.0% | 1.875% | 0.00% |
| 16 | Omega Fund Management, LLC | 876K | $6.0M | 0.0% | 1.712% | 3.66% |
| 17 | SR ONE CAPITAL MANAGEMENT, LP | 748K | $5.1M | 0.0% | 1.461% | 0.56% |
| 18 | Affinity Asset Advisors, LLC | 610K | $4.2M | -5.1% | 1.192% | 0.21% |
| 19 | Eversept Partners, LP | 511K | $3.5M | +12.0% | 0.997% | 0.18% |
| 20 | KENNEDY CAPITAL MANAGEMENT, INC. | 426K | $2.9M | +454.7% | 0.832% | 0.06% |
| 21 | Privium Fund Management B.V. | 352K | $2.4M | 0.0% | 0.688% | 0.50% |
| 22 | Monashee Investment Management LLC | 320K | $2.2M | +8.5% | 0.625% | 1.19% |
| 23 | Woodline Partners LP | 250K | $1.7M | 0.0% | 0.488% | 0.01% |
| 24 | Birchview Capital, LP | 250K | $1.7M | — | 0.488% | 0.97% |
| 25 | FMR LLC | 232K | $1.6M | — | 0.454% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ENGN — a direct measure of their conviction.
Filings activity in ENGN during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 58 | +1.8% | 199.99% | +0.00 pp | $380M | 28% |
| Q4 2025 | 57 | +50% | 199.99% | +0.00 pp | $529M | +90% |
| Q3 2025 | 38 | +0.0% | 199.99% | +75.20 pp | $279M | +90% |
| Q2 2025 | 38 | +19% | 124.79% | 75.20 pp | $147M | 20% |
| Q1 2025 | 32 | 8.6% | 199.99% | +0.00 pp | $183M | 33% |
| Q4 2024 | 35 | +13% | 199.99% | +6.87 pp | $275M | +21% |
| Q3 2024 | 31 | +0.0% | 193.12% | 6.87 pp | $228M | 26% |
| Q2 2024 | 31 | — | 199.99% | — | $307M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for ENGN.
Quick answers to the most common questions about buying ENGN stock.
Based on Q1 2026 13F filings, institutional ownership of enGene Holdings Inc. stands at 200.0%, held across 58 reporting institutions.
FCPM III SERVICES B.V. is the largest reported institutional holder of ENGN, with approximately 9,632,561 shares worth $0.07B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of ENGN.
Our composite Smart Money Score for ENGN is 38 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
12 institutions opened new positions in ENGN during Q1 2026, while 11 fully exited. 13 added to existing positions and 33 trimmed.
ENGN institutional ownership rose by 0.00 percentage points quarter-over-quarter, with a net change of +1 holders.
The top 10 institutions account for 77.2% of all reported 13F value in ENGN, and the top 25 account for 96.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.