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ENTOEntero Therapeutics, Inc.
$2.85$10M
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HomeStocksENTOCash Flow

Entero Therapeutics, Inc. (ENTO) Cash Flow Statement

13Y historyFree accessUpdated daily

Free cash flow remains deeply negative with a $4.0 million outflow in 2025Q4, highlighting a persistent disconnect between accounting losses and the cash required to sustain clinical operations.

ENTO Cash Flow Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18Dec'17Dec'16Dec'15Dec'14Dec'13
Cash from Operations-5.7M-9.22M-12.38M-22.34M-32.29M-11.22M-14.03K-10.87M-7.18M-4.53M-4.17K-1.01K57
Operating CF Margin %-15731.49%------------
Operating CF Growth %38.13%25.53%44.6%30.8%-187.73%-79862.49%99.87%-51.29%-58.43%-108642.99%-311.92%-1890.13%-
Net Income-6.55M-18.06M-15.79M-14.63M-58.54M-32.67M-15.18K-13.53M-11.1M-14.59M-5.93K-2.95K-1.01K
Depreciation & Amortization574.71K48.95K29.27K29.27K542.25K565.35K635798.45K754K734.5K73443412
Stock-Based Compensation733.95K631.55K1.04M769.12K1.37M549.42K1.39K2.84K2.02K604000
Deferred Taxes-418.63K000000000000
Other Non-Cash Items-39.27K5.63M157.02K277.43K3.46M5.4M3976.62M5.16M9.95M1.68K653-17
Working Capital Changes02.53M2.19M-10.5M17.1M14.15M-1.28K-1.71M-268.2K704.87K-6538531.08K
Change in Receivables7.29K093.01K-935512.08K-750-2.19M3.44K132.04K-63835638
Change in Inventory0000000000000
Change in Payables464.2K1.64M-165.76K-1.99M1.42M-750.03K-420.79K741.62K-233.78K0000
Cash from Investing323.48K88.17K-500K0-10.32M87.35K-24-305.47K-32.17K-12.36K-24-7520
Capital Expenditures00-500K0-10.32M-4.17K-24.1K-305.47K-32.17K-12.36K-24-1910
CapEx % of Revenue-------------
Acquisitions-8.72M88.17K00091.52K00000-5610
Investments-------------
Other Investing9.04M000-10.25K920000000
Cash from Financing5.89M5.58M15.23M15.74M44.76M17.05M13.14K11.71M6.01M5.75M4.68K1.85K-10
Debt Issued (Net)0-644.58K-603.49K-641.24K88.83K2.86M3.61M-190.68K1M1.89M5.02M991K0
Equity Issued (Net)06.23M15.83M23.25M39.77M14.19M9.48M11.9M5.01M5.28M0859.49K0
Dividends Paid-337.24K000000000000
Share Repurchases0000000000000
Other Financing6.23M45657-6.87M4.91M061.59K00-1.42M-340.52K0-10
Net Change in Cash714.79K-3.55M2.35M-6.86M2.19M5.89M-939540.87K-1.2M1.77M4488648
Free Cash Flow-5.7M-9.22M-12.88M-22.34M-42.61M-11.23M-38.13K-11.17M-7.22M-4.55M-4.2K-1.2K57
FCF Margin %-15731.49%------------
FCF Growth %38.13%28.42%42.37%47.56%-279.55%-29339.45%99.66%-54.84%-58.71%-108305.5%-248.57%-2227.87%-
FCF per Share-3.53-2.68-38.29-622.19-20049.05-16580.21-71.42-30399.11-28517.32-29360.37-18.02-5.170.24
FCF Conversion (FCF/Net Income)0.87x0.51x0.78x1.53x0.55x0.34x0.00x0.80x0.65x0.31x0.00x0.00x-0.06x
Interest Paid036.16K00000000000
Taxes Paid0000000000000

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Imminent liquidity and dilution

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2025Q4)

Earnings Disconnect Masks Cash Burn

According to recent financial statements, ENTO's operating cash flow consistently trails net income, with the 2025Q4 period showing a $4.0 million cash outflow despite a $3.1 million net loss, highlighting the persistent gap between accounting losses and the actual cash required to sustain clinical operations.

The divergence between net income and operating cash flow suggests that non-cash items and working capital adjustments are insufficient to bridge the company's fundamental funding gap. Investors should interpret this persistent negative cash flow as a signal that the company's clinical development costs are not being offset by any meaningful operational efficiency.

Negative Free Cash Flow Trajectory

As reported in quarterly filings, ENTO's free cash flow remains deeply negative, reaching a $4.0 million outflow in 2025Q4, which underscores the company's reliance on external capital markets to fund its ongoing research and development activities rather than generating internal cash from its clinical pipeline.

The lack of positive free cash flow is a structural reality for a pre-commercial entity, yet the magnitude of these outflows relative to the company's limited cash reserves warrants extreme caution. This trajectory suggests that without a significant change in funding strategy or clinical milestones, the company will continue to face severe liquidity pressure.

Working Capital Volatility Signals Instability

Based on historical data, ENTO's working capital changes have been erratic, with a $604,200 inflow in 2025Q2 followed by a $0 change in 2025Q4, indicating that management's ability to optimize cash cycles is secondary to the overwhelming pressure of funding clinical trial expenditures.

The inconsistency in working capital movements appears to reflect the timing of vendor payments and clinical trial milestones rather than operational improvements. Analysts should monitor these fluctuations as they may indicate the company's struggle to manage payables while maintaining critical research operations.

Capital Deployment Prioritizes Asset Acquisition

As indicated in recent SEC filings, ENTO utilized $8.7 million for acquisitions in 2025Q4, a move that significantly depleted available liquidity and shifted the company's strategic focus toward the latiglutenase program at the expense of its already strained cash position.

This aggressive deployment of capital into intangible assets suggests a high-stakes pivot intended to secure a viable clinical future. However, the timing of such expenditures, given the company's limited cash runway, implies a high degree of risk regarding the company's ability to sustain operations through the next phase of development.

ENTO — Frequently Asked Questions

Quick answers to the most common questions about buying ENTO stock.

How much cash does Entero Therapeutics, Inc. (ENTO) generate from operations?

Entero Therapeutics, Inc. (ENTO) generated $-5.7M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.

What is Entero Therapeutics, Inc.'s free cash flow?

Entero Therapeutics, Inc. (ENTO) reported negative free cash flow of $5.7M in 2025, indicating capital requirements exceeded cash from operations.

What is Entero Therapeutics, Inc.'s capital expenditure (CapEx)?

Entero Therapeutics, Inc. (ENTO) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.

How does Entero Therapeutics, Inc. distribute cash to shareholders?

In 2025, Entero Therapeutics, Inc. (ENTO) returned $0.3M to shareholders via cash dividends. This shows the company's commitment to returning capital to its equity investors.