79% buyers of institutions opening or closing positions this quarter
14 more new buyers than exits, ownership rose 11.68 percentage points vs the prior quarter, and 3 well-known fund managers in the top 25.
79% buyers of institutions opening or closing positions this quarter
36.4% institutional ownership
Decheng Capital LLC portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in EQ across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in EQ held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON GROUP PLC | 6.5M | $13.0M | +10.8% | 6.746% | 0.01% |
| 2 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 5.3M | $10.7M | 0.0% | 5.535% | 0.02% |
| 3 | Decheng Capital LLC | 4.4M | $8.9M | 0.0% | 4.619% | 1.34% |
| 4 | ADAR1 Capital Management, LLC | 3.7M | $7.5M | -33.6% | 3.871% | 0.44% |
| 5 | Woodline Partners LP | 3.5M | $7.0M | 0.0% | 3.636% | 0.03% |
| 6 | abrdn plc | 3.4M | $6.7M | +41.7% | 3.482% | 0.01% |
| 7 | RA CAPITAL MANAGEMENT, L.P. | 3.1M | $6.2M | β | 3.216% | 0.07% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 1.8M | $3.6M | β | 1.853% | 0.00% |
| 9 | BALYASNY ASSET MANAGEMENT LLC | 1.6M | $3.3M | -21.1% | 1.702% | 0.00% |
| 10 | Eversept Partners, LP | 1.5M | $3.0M | β | 1.557% | 0.16% |
| 11 | Affinity Asset Advisors, LLC | 1.2M | $2.5M | β | 1.274% | 0.13% |
| 12 | RENAISSANCE TECHNOLOGIES LLC | 657K | $1.3M | -10.4% | 0.682% | 0.00% |
| 13 | DIADEMA PARTNERS LP | 434K | $868K | +24.9% | 0.451% | 0.15% |
| 14 | Hudson Bay Capital Management LP | 429K | $857K | 0.0% | 0.445% | 0.00% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 379K | $758K | +9.7% | 0.394% | 0.00% |
| 16 | Ikarian Capital, LLC | 304K | $607K | 0.0% | 0.315% | 0.05% |
| 17 | CANTOR FITZGERALD, L. P. | 263K | $525K | -53.3% | 0.273% | 0.01% |
| 18 | TWO SIGMA INVESTMENTS, LP | 246K | $492K | -24.2% | 0.256% | 0.00% |
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 231K | $462K | +1.5% | 0.240% | 0.00% |
| 20 | JANE STREET GROUP, LLC | 221K | $442K | +78.2% | 0.230% | 0.00% |
| 21 | CITADEL ADVISORS LLC | 190K | $380K | β | 0.197% | 0.00% |
| 22 | VANGUARD FIDUCIARY TRUST CO | 190K | $379K | β | 0.197% | 0.00% |
| 23 | STATE STREET CORP | 174K | $348K | +12.0% | 0.181% | 0.00% |
| 24 | BlackRock, Inc. | 128K | $256K | +1.4% | 0.133% | 0.00% |
| 25 | Persistent Asset Partners Ltd | 110K | $220K | +18.3% | 0.114% | 0.08% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in EQ β a direct measure of their conviction.
Filings activity in EQ during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new EQ position in Q1 2026
Institutions that fully closed their EQ position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 51 | +38% | 36.38% | +11.68 pp | $81M | +47% |
| Q4 2025 | 37 | 7.5% | 24.70% | +5.79 pp | $55M | +31% |
| Q3 2025 | 40 | +38% | 18.91% | +17.69 pp | $42M | +1455% |
| Q2 2025 | 29 | +16% | 1.22% | 0.26 pp | $3M | 18% |
| Q1 2025 | 25 | 11% | 1.48% | 5.10 pp | $3M | 77% |
| Q4 2024 | 28 | +3.7% | 6.58% | +4.07 pp | $15M | +163% |
| Q3 2024 | 27 | +3.8% | 2.51% | +0.36 pp | $6M | +17% |
| Q2 2024 | 26 | β | 2.15% | β | $5M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for EQ.
Quick answers to the most common questions about buying EQ stock.
Based on Q1 2026 13F filings, institutional ownership of Equillium, Inc. stands at 36.4%, held across 51 reporting institutions.
JANUS HENDERSON GROUP PLC is the largest reported institutional holder of EQ, with approximately 6,494,571 shares worth $0.01B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of EQ, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for EQ is 78 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
19 institutions opened new positions in EQ during Q1 2026, while 5 fully exited. 23 added to existing positions and 7 trimmed.
EQ institutional ownership rose by 11.68 percentage points quarter-over-quarter, with a net change of β holders.
The top 10 institutions account for 85.8% of all reported 13F value in EQ, and the top 25 account for 98.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.